BR9811846A - Derivados microbicidas de n-sulfonilglicina alquiniloxifenetil amida - Google Patents

Derivados microbicidas de n-sulfonilglicina alquiniloxifenetil amida

Info

Publication number
BR9811846A
BR9811846A BR9811846-3A BR9811846A BR9811846A BR 9811846 A BR9811846 A BR 9811846A BR 9811846 A BR9811846 A BR 9811846A BR 9811846 A BR9811846 A BR 9811846A
Authority
BR
Brazil
Prior art keywords
alkyl
cycloalkyl
alkynyl
unsubstituted
alkenyl
Prior art date
Application number
BR9811846-3A
Other languages
English (en)
Other versions
BR9811846B1 (pt
Inventor
Martin Zeller
Andre Jeanguenat
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BR9811846A publication Critical patent/BR9811846A/pt
Publication of BR9811846B1 publication Critical patent/BR9811846B1/pt

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/03Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C311/06Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms to acyclic carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N41/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom
    • A01N41/02Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom containing a sulfur-to-oxygen double bond
    • A01N41/04Sulfonic acids; Derivatives thereof
    • A01N41/06Sulfonic acid amides
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/06Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings
    • A01N43/10Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings with sulfur as the ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/60Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/08Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C307/00Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C307/04Diamides of sulfuric acids
    • C07C307/06Diamides of sulfuric acids having nitrogen atoms of the sulfamide groups bound to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/11Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic unsaturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C313/00Sulfinic acids; Sulfenic acids; Halides, esters or anhydrides thereof; Amides of sulfinic or sulfenic acids, i.e. compounds having singly-bound oxygen atoms of sulfinic or sulfenic groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C313/02Sulfinic acids; Derivatives thereof
    • C07C313/06Sulfinamides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Patente de Invenção: <B>"DERIVADOS MICROBICIDAS DE N-SULFONILGLICINA ALQUINILOXIFENETIL AMIDA"<D>. A invenção refere-se a novos compostos da fórmula geral I pesticidamente ativos assim como aos isómeros possíveis e misturas de isómeros dos mesmos, onde n é o número zero ou um; e R~ 1~ é C~ 1-C~ 12~ alquila que é não-substituída ou pode ser substituída com C~ 1~-C~ 4~ alcóxi, C~ 1~-C~ 4~ alquiltio, C~ 1~-C~ C4~ alquilsulfonila, C~ 3~-C~ 8~ cicloalquila, ciano, C~ 1~-C~ 6~ alcoxicarbonila, C~ 3~-C~ 6~ alqueniloxicarbonila ou com C~ 3~-C~ 6~ alquiniloxicarbonila; C~ 3~-C~ 8~ cicloalquila; C~ 2~-C~ 12~ alquenila; C~ 2~-C~ 12~ alquinila; C~ 1~-C~ 12~ haloalquila; ou um grupo NR~ 11~R~ 12~ onde R~ 11~ e R~ 12~ são independentemente um do outro hidrogênio ou C~ 1~-C~ 6~ alquila, ou juntos são tetra- ou pentametileno; R~ 2~ e R~ 3~ são independentemente um do outro hidrogênio; C~ 1~-C~ 8~ alquila; C~ 1~-C~ 8~ alquila substituída com hidróxi, C~ 1~-C~ 4~ alcóxi, mercapto ou com C~ 1~-C~ 4~ alquiltio; C~ 3~-C~ 8~ alquenila; C~ 3~-C~ 8~ alquinila; C~ 3~-C~ 8~ cicloalquila; C~ 3~-C~ 8~ cicloalquil-C~ 1~-C~ 4~ alquila; ou os dois grupos R~ 2~ e R~ 3~ juntos com o átomo de carbono ao qual estão ligados formam um anel de três a oito membros; R~ 4~, R~ 5~, R~ 6~ e R~ 7~ são iguais ou diferentes e cada um é independentemente dos outros hidrogênio ou C~ 1~-C~ 4~ alquila; R~ 8~ é C~ 1~-C~ 6~ alquila, C~ 3~-C~ 6~ alquenila ou C~ 3~-C~ 6~ alquinila; A é C~ 1~-C~ 6~ alquileno; e B é arila não-substituída ou substituída, opcionalmente mono ou polinuclear; heteroarila não-substituída ou substituída, opcionalmente mono ou polinuclear; C~ 4~-C~ 12~ alquila; ou C~ 3~-C~ 8~ cicloalquila. Os compostos possuem propriedades protetoras de plantas e são adequados para proteger plantas contra infestação por microorganismos fitopatogênicos.
BRPI9811846-3A 1997-08-06 1998-08-04 compostos derivados microbicidas de n-sulfonilglicina alquiniloxifenetil amida, seu uso e processo de preparação, composição e método para controle e prevenção contra microorganismos fitopatogênicos, bem como intermediários e seus respectivos processos de preparação. BR9811846B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH1864/97 1997-08-06
CH186497 1997-08-06
PCT/EP1998/004849 WO1999007674A2 (en) 1997-08-06 1998-08-04 Microbicidal n-sulfonylglycin alkynyloxyphenemethyl amide derivatives

Publications (2)

Publication Number Publication Date
BR9811846A true BR9811846A (pt) 2000-08-08
BR9811846B1 BR9811846B1 (pt) 2010-03-09

Family

ID=4220395

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9811846-3A BR9811846B1 (pt) 1997-08-06 1998-08-04 compostos derivados microbicidas de n-sulfonilglicina alquiniloxifenetil amida, seu uso e processo de preparação, composição e método para controle e prevenção contra microorganismos fitopatogênicos, bem como intermediários e seus respectivos processos de preparação.

Country Status (24)

Country Link
US (1) US6482859B1 (pt)
EP (1) EP1003719B1 (pt)
JP (1) JP4163379B2 (pt)
KR (1) KR100609625B1 (pt)
CN (1) CN1215054C (pt)
AR (1) AR013391A1 (pt)
AT (1) ATE218540T1 (pt)
AU (1) AU738007B2 (pt)
BR (1) BR9811846B1 (pt)
CA (1) CA2293451A1 (pt)
DE (1) DE69805807T2 (pt)
DK (1) DK1003719T3 (pt)
ES (1) ES2178259T3 (pt)
GT (1) GT199800109A (pt)
HU (1) HUP0004819A3 (pt)
IL (1) IL134266A (pt)
NZ (1) NZ502508A (pt)
PL (1) PL195781B1 (pt)
PT (1) PT1003719E (pt)
RU (1) RU2221778C2 (pt)
TR (1) TR200000213T2 (pt)
TW (1) TW491832B (pt)
WO (1) WO1999007674A2 (pt)
ZA (1) ZA987017B (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9826650D0 (en) * 1998-12-03 1999-01-27 Novartis Ag Organic compounds
TW564244B (en) * 1999-01-11 2003-12-01 Novartis Ag Novel propargylether derivatives
AR033800A1 (es) * 2000-01-25 2004-01-07 Syngenta Participations Ag Derivados de 3-fenoxi-1-fenilacetileno sustituido, metodo para la preparacion de dichos derivados, composicion herbicida e inhibidora del crecimiento de las plantas, metodo para controlar el desarrollo de plantas perjudiciales, metodo para inhibir el desarrollo de plantas perjudiciales, y uso de dic
GB0011944D0 (en) 2000-05-17 2000-07-05 Novartis Ag Organic compounds
US20030189958A1 (en) * 2000-09-12 2003-10-09 Cosima Nuninger Fungicidal compositions
GB0022338D0 (en) * 2000-09-12 2000-10-25 Novartis Ag Organic Compounds
GB0127554D0 (en) * 2001-11-16 2002-01-09 Syngenta Participations Ag Organic compounds
GB0227966D0 (en) * 2002-11-29 2003-01-08 Syngenta Participations Ag Organic Compounds
EP1605011B1 (en) 2003-02-28 2013-01-23 Daikin Industries, Ltd. Granulated powder of low-molecular polytetrafluoro- ethylene and powder of low-molecular polytetrafluoro- ethylene and processes for producing both
GB0403864D0 (en) 2004-02-20 2004-03-24 Ucl Ventures Modulator
BRPI0520306B1 (pt) * 2004-08-17 2014-08-26 Syngenta Participations Ag Composições aquosas inseticidas formuladas, material de propagação de planta resistente a pragas e método para sua proteção, e sistema de armazenamento e transporte
PE20060796A1 (es) 2004-11-25 2006-09-29 Basf Ag Procedimiento para intensificar la eficiencia de etaboxam
GB0516705D0 (en) * 2005-08-15 2005-09-21 Syngenta Participations Ag Process
US9266984B2 (en) 2008-09-30 2016-02-23 Raytech Corporation Polytetrafluoroethylene resins that can be processed by shaping, shaped products thereof, and processes for producing the resins and shaped products
CN101503381B (zh) * 2009-03-05 2012-09-05 中国农业大学 1-氧代四氢萘基-2-磺酰胺,其制备方法和作为杀菌剂的用途
GB0906515D0 (en) 2009-04-15 2009-05-20 Syngenta Participations Ag Fungical compositions
PL2636668T3 (pl) * 2010-11-05 2019-03-29 Oat Agrio Co., Ltd. Związek etynylofenyloamidynowy jego sól, sposób jego wytwarzania i fungicyd do zastosowania w rolnictwie i ogrodnictwie
CN108503508B (zh) * 2018-05-14 2021-02-02 广州润霖医药科技有限公司 一种抗凝血药物替卡格雷原料中间体的合成方法
CN108503528B (zh) * 2018-05-14 2021-02-09 韦丽 一种抗凝血药物替卡格雷中间体原料的合成方法
WO2021218863A1 (zh) * 2020-04-26 2021-11-04 江苏恩华药业股份有限公司 1,5-二氢-2,4-苯二氮䓬-3-酮衍生物及其应用
CN112110800B (zh) * 2020-09-25 2022-06-24 哈尔滨工业大学(深圳) 一种3-芳基-2-丙炔-1-醇类衍生物及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RO117375B1 (ro) * 1994-05-04 2002-02-28 Novartis Ag Derivaţi amidici n-sulfonil şi n-sulfinil de a-aminoacizi, procedee pentru prepararea acestora, compoziţie microbicidă şi metodă de control şi prevenire a infestării plantelor
PL185836B1 (pl) * 1995-10-18 2003-08-29 Syngenta Participations Ag N-sulfonylowe pochodne aminokwasów, sposób otrzymyN-sulfonylowe pochodne aminokwasów, sposób otrzymywania N-sulfonylowych pochodnych aminokwasów orazwania N-sulfonylowych pochodnych aminokwasów orazkompozycja do zwalczania i zapobiegania inwazji fikompozycja do zwalczania i zapobiegania inwazji fitopatogennych grzybów na uprawy roślinnetopatogennych grzybów na uprawy roślinne
PT968178E (pt) * 1997-02-25 2002-11-29 Syngenta Participations Ag N-sulfonil e n-sulfinil amidas de aminoacidos como microbicidas
JP2001515474A (ja) * 1997-02-25 2001-09-18 ノバルティス アクチェンゲゼルシャフト 殺微生物剤としてのn−スルホニル及びn−スルフィニルアミノ酸アミド

Also Published As

Publication number Publication date
KR20010022635A (ko) 2001-03-26
TW491832B (en) 2002-06-21
ES2178259T3 (es) 2002-12-16
EP1003719B1 (en) 2002-06-05
WO1999007674A3 (en) 1999-04-15
DE69805807D1 (de) 2002-07-11
RU2221778C2 (ru) 2004-01-20
JP4163379B2 (ja) 2008-10-08
PT1003719E (pt) 2002-10-31
US6482859B1 (en) 2002-11-19
WO1999007674A2 (en) 1999-02-18
AU738007B2 (en) 2001-09-06
BR9811846B1 (pt) 2010-03-09
HUP0004819A2 (hu) 2001-05-28
ZA987017B (en) 1999-02-08
DK1003719T3 (da) 2002-10-14
AU9338898A (en) 1999-03-01
KR100609625B1 (ko) 2006-08-09
EP1003719A2 (en) 2000-05-31
PL337827A1 (en) 2000-09-11
IL134266A (en) 2005-11-20
ATE218540T1 (de) 2002-06-15
TR200000213T2 (tr) 2000-08-21
PL195781B1 (pl) 2007-10-31
IL134266A0 (en) 2001-04-30
AR013391A1 (es) 2000-12-27
HUP0004819A3 (en) 2002-01-28
DE69805807T2 (de) 2003-02-06
CN1266426A (zh) 2000-09-13
JP2001513529A (ja) 2001-09-04
GT199800109A (es) 2000-01-13
CN1215054C (zh) 2005-08-17
NZ502508A (en) 2002-05-31
CA2293451A1 (en) 1999-02-18

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B25A Requested transfer of rights approved

Owner name: SYNGENTA PARTICIPATIONS AG (CH)

Free format text: TRANSFERIDO DE: NOVARTIS AG (NOVARTIS SA) (NOVARTIS INC.)

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 09/03/2010, OBSERVADAS AS CONDICOES LEGAIS.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time
B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)