BR9407079A - Imidazois tri-substituídos possuindo múltiplas propriedades terapêuticas - Google Patents

Imidazois tri-substituídos possuindo múltiplas propriedades terapêuticas

Info

Publication number
BR9407079A
BR9407079A BR9407079A BR9407079A BR9407079A BR 9407079 A BR9407079 A BR 9407079A BR 9407079 A BR9407079 A BR 9407079A BR 9407079 A BR9407079 A BR 9407079A BR 9407079 A BR9407079 A BR 9407079A
Authority
BR
Brazil
Prior art keywords
imidazois
tri
substituted
therapeutic properties
multiple therapeutic
Prior art date
Application number
BR9407079A
Other languages
English (en)
Inventor
Jerry Leroy Adams
Peter William Sheldrake
Timothy Francis Gallagher
Ravi Shanker Garigipati
Paul Elliot Bender
Jeffrey Charles Boehm
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of BR9407079A publication Critical patent/BR9407079A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Emergency Medicine (AREA)
  • Toxicology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
BR9407079A 1993-07-16 1994-07-15 Imidazois tri-substituídos possuindo múltiplas propriedades terapêuticas BR9407079A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9273393A 1993-07-16 1993-07-16
PCT/US1994/007969 WO1995002591A1 (en) 1993-07-16 1994-07-15 Tri-substituted imidazoles having multiple therapeutic properties

Publications (1)

Publication Number Publication Date
BR9407079A true BR9407079A (pt) 1996-08-27

Family

ID=22234840

Family Applications (2)

Application Number Title Priority Date Filing Date
BR9407079A BR9407079A (pt) 1993-07-16 1994-07-15 Imidazois tri-substituídos possuindo múltiplas propriedades terapêuticas
BR1100546-7A BR1100546A (pt) 1993-07-16 1997-05-13 Compostos e composições de piridil imidazol.

Family Applications After (1)

Application Number Title Priority Date Filing Date
BR1100546-7A BR1100546A (pt) 1993-07-16 1997-05-13 Compostos e composições de piridil imidazol.

Country Status (31)

Country Link
EP (5) EP1291346B1 (pt)
JP (4) JPH09500137A (pt)
CN (2) CN1050126C (pt)
AP (1) AP484A (pt)
AT (2) ATE291576T1 (pt)
AU (1) AU694130C (pt)
BR (2) BR9407079A (pt)
CA (1) CA2167311A1 (pt)
CZ (1) CZ11996A3 (pt)
DE (2) DE69432463T2 (pt)
DK (1) DK0708768T3 (pt)
DZ (1) DZ1798A1 (pt)
ES (2) ES2237650T3 (pt)
FI (1) FI960177A0 (pt)
HK (4) HK1049658A1 (pt)
HU (1) HUT75313A (pt)
IL (2) IL110296A (pt)
MA (1) MA23270A1 (pt)
MY (1) MY116478A (pt)
NO (4) NO316881B1 (pt)
NZ (2) NZ329994A (pt)
PL (4) PL181723B1 (pt)
PT (1) PT708768E (pt)
RU (1) RU2140918C1 (pt)
SG (1) SG52368A1 (pt)
SI (1) SI0708768T1 (pt)
SK (1) SK282342B6 (pt)
TW (1) TW330934B (pt)
UA (1) UA63875C2 (pt)
WO (1) WO1995002591A1 (pt)
ZA (1) ZA945193B (pt)

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EP0563286A4 (en) * 1990-12-13 1995-01-11 Smithkline Beecham Corp Novel csaids
KR930703321A (ko) * 1990-12-13 1993-11-29 스튜어트 알. 슈터 신규한 사이토킨 억제성 소염 의약
IL104369A0 (en) * 1992-01-13 1993-05-13 Smithkline Beecham Corp Novel compounds and compositions

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JP2004099622A (ja) 2004-04-02
JPH09500137A (ja) 1997-01-07
PT708768E (pt) 2003-08-29
EP0708768A4 (en) 1996-08-21
CN1218801A (zh) 1999-06-09
ATE236896T1 (de) 2003-04-15
NO10837A (no) 1996-01-15
AU7185098A (en) 1998-08-27
HK1049658A1 (zh) 2003-05-23
EP1227092A3 (en) 2002-08-07
EP1229035A1 (en) 2002-08-07
HUT75313A (en) 1997-05-28
SI0708768T1 (en) 2003-10-31
EP1291346B1 (en) 2005-03-23
CN1050126C (zh) 2000-03-08
AU694130B2 (en) 1998-07-16
DZ1798A1 (fr) 2002-02-17
AP484A (en) 1996-04-23
NZ329994A (en) 1999-07-29
UA63875C2 (en) 2004-02-16
ZA945193B (en) 1995-04-20
EP0708768A1 (en) 1996-05-01
CN1129447A (zh) 1996-08-21
PL312614A1 (en) 1996-04-29
DE69432463D1 (de) 2003-05-15
DE69434316T2 (de) 2006-03-09
EP1227092A2 (en) 2002-07-31
MA23270A1 (fr) 1995-04-01
EP1291346A1 (en) 2003-03-12
DK0708768T3 (da) 2003-08-04
HK1012392A1 (en) 1999-07-30
SG52368A1 (en) 1998-09-28
RU2140918C1 (ru) 1999-11-10
NO960173L (no) 1996-01-15
PL181705B1 (pl) 2001-09-28
EP0708768B1 (en) 2003-04-09
FI960177A (fi) 1996-01-15
DE69434316D1 (de) 2005-04-28
CZ11996A3 (en) 1996-10-16
FI960177A0 (fi) 1996-01-15
WO1995002591A1 (en) 1995-01-26
HU9503855D0 (en) 1996-02-28
JP2004149541A (ja) 2004-05-27
IL110296A (en) 1999-12-31
NO20010838D0 (no) 2001-02-19
AU7335494A (en) 1995-02-13
ATE291576T1 (de) 2005-04-15
NZ269457A (en) 1998-08-26
NO10839A (no) 1996-01-15
AP9400654A0 (en) 1994-07-31
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NO20010839D0 (no) 2001-02-19
NO960173D0 (no) 1996-01-15
PL181723B1 (pl) 2001-09-28
BR1100546A (pt) 2004-08-31
ES2197167T3 (es) 2004-01-01
IL124318A0 (en) 1998-12-06
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NO10838A (no) 1996-01-15
AU694130C (en) 2002-12-05
SK282342B6 (sk) 2002-01-07
IL110296A0 (en) 1994-10-21
ES2237650T3 (es) 2005-08-01
EP1227091A3 (en) 2002-08-07
EP1227091A2 (en) 2002-07-31
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HK1049657A1 (zh) 2003-05-23
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DE69432463T2 (de) 2004-02-12
CA2167311A1 (en) 1995-01-26

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