BR9406820A - Reagente para a preparação de produto radiofarmacêutico conjuntos produtos radiofarmacêuticos métodos para visualizar os locais de deposição das palquetas compostos radio-rotulados composição radiofarmacêutica método para determinar a deposição das plaquetas e método para diagnosticar um disturbio - Google Patents
Reagente para a preparação de produto radiofarmacêutico conjuntos produtos radiofarmacêuticos métodos para visualizar os locais de deposição das palquetas compostos radio-rotulados composição radiofarmacêutica método para determinar a deposição das plaquetas e método para diagnosticar um disturbioInfo
- Publication number
- BR9406820A BR9406820A BR9406820A BR9406820A BR9406820A BR 9406820 A BR9406820 A BR 9406820A BR 9406820 A BR9406820 A BR 9406820A BR 9406820 A BR9406820 A BR 9406820A BR 9406820 A BR9406820 A BR 9406820A
- Authority
- BR
- Brazil
- Prior art keywords
- radiopharmaceutical
- deposition
- preparation
- pallets
- visualizing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/75—Fibrinogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/082—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being a RGD-containing peptide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/008—Peptides; Proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4033693A | 1993-03-30 | 1993-03-30 | |
US08/218,861 US5879657A (en) | 1993-03-30 | 1994-03-28 | Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders |
PCT/US1994/003256 WO1994022494A1 (en) | 1993-03-30 | 1994-03-29 | RADIOLABELED PLATELET GPIIb/IIIa RECEPTOR ANTAGONISTS AS IMAGING AGENTS FOR THE DIAGNOSIS OF THROMBOEMBOLIC DISORDERS |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9406820A true BR9406820A (pt) | 1996-09-10 |
Family
ID=21910453
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9406820A BR9406820A (pt) | 1993-03-30 | 1994-03-29 | Reagente para a preparação de produto radiofarmacêutico conjuntos produtos radiofarmacêuticos métodos para visualizar os locais de deposição das palquetas compostos radio-rotulados composição radiofarmacêutica método para determinar a deposição das plaquetas e método para diagnosticar um disturbio |
BR9406055A BR9406055A (pt) | 1993-03-30 | 1994-03-29 | Reagente para a preparação de produto radiofarmacêutico conjuntos produtos radiofarmacêuticos métodos para visualizar os locais de deposição das palquetas compostos radio-rotulados composição radiofarmacêutica método para determinar a deposição das plaquetas e método para diagnosticar um disturbio |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9406055A BR9406055A (pt) | 1993-03-30 | 1994-03-29 | Reagente para a preparação de produto radiofarmacêutico conjuntos produtos radiofarmacêuticos métodos para visualizar os locais de deposição das palquetas compostos radio-rotulados composição radiofarmacêutica método para determinar a deposição das plaquetas e método para diagnosticar um disturbio |
Country Status (26)
Country | Link |
---|---|
US (2) | US5879657A (pt) |
EP (2) | EP0692982B1 (pt) |
JP (1) | JP3042887B2 (pt) |
KR (1) | KR960701666A (pt) |
CN (1) | CN1122577A (pt) |
AT (1) | ATE194293T1 (pt) |
AU (2) | AU6524894A (pt) |
BG (1) | BG100036A (pt) |
BR (2) | BR9406820A (pt) |
CA (1) | CA2159445A1 (pt) |
DE (1) | DE69425138T2 (pt) |
DK (1) | DK0692982T3 (pt) |
ES (1) | ES2149266T3 (pt) |
FI (1) | FI954655A (pt) |
GR (1) | GR3034272T3 (pt) |
HU (1) | HUT72889A (pt) |
LV (1) | LV11106B (pt) |
NO (1) | NO307568B1 (pt) |
NZ (1) | NZ263970A (pt) |
PL (1) | PL178252B1 (pt) |
PT (1) | PT692982E (pt) |
RU (1) | RU2145608C1 (pt) |
TW (1) | TW445267B (pt) |
UA (1) | UA32577C2 (pt) |
WO (1) | WO1994022494A1 (pt) |
ZA (1) | ZA942262B (pt) |
Families Citing this family (53)
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US5736122A (en) * | 1991-02-08 | 1998-04-07 | Diatide, Inc. | Technetium-99m labeled peptides for thrombus imaging |
KR930703024A (ko) * | 1991-02-08 | 1993-11-29 | 리챠드 티. 딘 | 영상용 테크네튬-99m표지폴리펩티드 |
US5645815A (en) * | 1991-02-08 | 1997-07-08 | Diatide, Inc. | Radiolabled compounds for thrombus imaging |
US6083481A (en) * | 1992-05-21 | 2000-07-04 | Diatide, Inc. | Thrombus imaging agents |
US5968476A (en) * | 1992-05-21 | 1999-10-19 | Diatide, Inc. | Technetium-99m labeled peptides for thrombus imaging |
US5744120A (en) * | 1993-03-30 | 1998-04-28 | The Dupont Merick Pharmaceutical Company | Ternary radiopharmaceutical complexes |
US5879657A (en) * | 1993-03-30 | 1999-03-09 | The Dupont Merck Pharmaceutical Company | Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders |
US5750088A (en) * | 1993-03-30 | 1998-05-12 | The Dupont Merck Pharmaceutical Company | Stable hydrazones linked to a peptide moiety as reagents for the preparation of radiopharmaceuticals |
EP0693941B1 (en) * | 1993-04-08 | 2002-07-24 | Diatide, Inc. | Radiolabeled compounds for thrombus imaging |
ES2157422T3 (es) * | 1995-02-07 | 2001-08-16 | Brusilow Entpr Llc | Trigliceridos y esteres etilicos de acido fenilalcanoico y acido fenilalquenoico utiles en el tratamiento de diversos trastornos. |
ES2201284T3 (es) * | 1996-03-13 | 2004-03-16 | Bristol-Myers Squibb Pharma Company | Nuevos complejos radiofarmaceuticos ternarios. |
US5879659A (en) * | 1996-03-13 | 1999-03-09 | Dupont Pharmaceuticals Company | Ternary radiopharmaceutical complexes |
WO1997047329A2 (en) * | 1996-06-10 | 1997-12-18 | G.D. Searle & Co. | Radiopharmaceutical compositions capable of localizing at sites of thrombus |
ZA978758B (en) * | 1996-10-02 | 1999-03-30 | Du Pont Merck Pharma | Technetium-99m-labeled chelator incorporated cyclic peptides that bind to the GPIIb/IIIa receptor as imaging agents |
BR9712281A (pt) * | 1996-10-07 | 1999-08-31 | Du Pont Pharm Co | Reagentes, kit, agente de ligação de ltb4 radiorotulado, método para detectar locais de infecção e inflamação em um mamífero, método para a formação da imagem de locais de infecção e inflamação em um mamífero, método para diagnosticar doença em um mamífero associado com minfecção e inflamação, compostos e método de tratamento de doença em um mamífero associado com infecção e inflamação |
WO1999040882A2 (en) * | 1998-02-06 | 1999-08-19 | Trustees Of The University Of Pennsylvania | STEREOSELECTIVE Tc-99m LIGANDS |
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US6171578B1 (en) * | 1999-04-14 | 2001-01-09 | Diatide, Inc. | Benzodiazepine derivatives for imaging thrombi |
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US7045286B2 (en) | 2000-07-25 | 2006-05-16 | The Trustees Of The University Of Pennsylvania | Methods of detecting molecules expressing selected epitopes via fluorescent dyes |
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US7341831B2 (en) * | 2001-07-18 | 2008-03-11 | The Trustees Of The University Of Pennsylvania | Method for immuno-detection of epitopes |
WO2003099845A2 (en) | 2002-05-23 | 2003-12-04 | Trustees Of The University Of Pennsylvania | Fas peptide mimetics and uses thereof |
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WO2005027981A1 (en) * | 2003-09-17 | 2005-03-31 | Board Of Regents, The University Of Texas System | Mechanism-based targeted pancreatic beta cell imaging and therapy |
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WO2005081898A2 (en) | 2004-02-20 | 2005-09-09 | The Trustees Of The University Of Pennsylvania | Binding peptidomimetics and uses of the same |
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-
1994
- 1994-03-28 US US08/218,861 patent/US5879657A/en not_active Expired - Fee Related
- 1994-03-29 DK DK94912870T patent/DK0692982T3/da active
- 1994-03-29 ES ES94912870T patent/ES2149266T3/es not_active Expired - Lifetime
- 1994-03-29 UA UA95094341A patent/UA32577C2/uk unknown
- 1994-03-29 NZ NZ263970A patent/NZ263970A/en unknown
- 1994-03-29 HU HU9502862A patent/HUT72889A/hu unknown
- 1994-03-29 DE DE69425138T patent/DE69425138T2/de not_active Expired - Fee Related
- 1994-03-29 BR BR9406820A patent/BR9406820A/pt not_active Application Discontinuation
- 1994-03-29 CA CA002159445A patent/CA2159445A1/en not_active Abandoned
- 1994-03-29 PT PT94912870T patent/PT692982E/pt unknown
- 1994-03-29 BR BR9406055A patent/BR9406055A/pt not_active Application Discontinuation
- 1994-03-29 AU AU65248/94A patent/AU6524894A/en not_active Abandoned
- 1994-03-29 AT AT94912870T patent/ATE194293T1/de not_active IP Right Cessation
- 1994-03-29 JP JP6522205A patent/JP3042887B2/ja not_active Expired - Fee Related
- 1994-03-29 RU RU95118183A patent/RU2145608C1/ru active
- 1994-03-29 PL PL94311037A patent/PL178252B1/pl unknown
- 1994-03-29 CN CN94192010A patent/CN1122577A/zh active Pending
- 1994-03-29 WO PCT/US1994/003256 patent/WO1994022494A1/en active IP Right Grant
- 1994-03-29 EP EP94912870A patent/EP0692982B1/en not_active Expired - Lifetime
- 1994-03-29 EP EP99116915A patent/EP0995761A3/en not_active Withdrawn
- 1994-03-30 ZA ZA942262A patent/ZA942262B/xx unknown
- 1994-05-07 TW TW083104199A patent/TW445267B/zh active
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1995
- 1995-09-29 KR KR1019950704228A patent/KR960701666A/ko not_active Application Discontinuation
- 1995-09-29 BG BG100036A patent/BG100036A/bg unknown
- 1995-09-29 FI FI954655A patent/FI954655A/fi not_active IP Right Cessation
- 1995-09-29 NO NO953886A patent/NO307568B1/no unknown
- 1995-10-27 LV LVP-95-296A patent/LV11106B/en unknown
- 1995-10-30 AU AU34525/95A patent/AU689643B2/en not_active Ceased
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1997
- 1997-12-29 US US08/999,400 patent/US6022523A/en not_active Expired - Fee Related
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2000
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