DE69002623D1 - Verfahren zur abtrennung und reinigung von sialyl-transferasen. - Google Patents

Verfahren zur abtrennung und reinigung von sialyl-transferasen.

Info

Publication number
DE69002623D1
DE69002623D1 DE9090906090T DE69002623T DE69002623D1 DE 69002623 D1 DE69002623 D1 DE 69002623D1 DE 9090906090 T DE9090906090 T DE 9090906090T DE 69002623 T DE69002623 T DE 69002623T DE 69002623 D1 DE69002623 D1 DE 69002623D1
Authority
DE
Germany
Prior art keywords
specific
sialyl
separating
cleaning
lacnac
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE9090906090T
Other languages
English (en)
Other versions
DE69002623T2 (de
Inventor
M Mazid
Mohammed Kashem
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chembiomed Ltd
Original Assignee
Chembiomed Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chembiomed Ltd filed Critical Chembiomed Ltd
Application granted granted Critical
Publication of DE69002623D1 publication Critical patent/DE69002623D1/de
Publication of DE69002623T2 publication Critical patent/DE69002623T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/803—Physical recovery methods, e.g. chromatography, grinding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y10S435/815—Enzyme separation or purification by sorption

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
DE90906090T 1989-04-12 1990-04-12 Verfahren zur abtrennung und reinigung von sialyl-transferasen. Expired - Fee Related DE69002623T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/336,932 US5059535A (en) 1989-04-12 1989-04-12 Process for the separation and purification of sialyl transferases

Publications (2)

Publication Number Publication Date
DE69002623D1 true DE69002623D1 (de) 1993-09-09
DE69002623T2 DE69002623T2 (de) 1993-11-25

Family

ID=23318345

Family Applications (1)

Application Number Title Priority Date Filing Date
DE90906090T Expired - Fee Related DE69002623T2 (de) 1989-04-12 1990-04-12 Verfahren zur abtrennung und reinigung von sialyl-transferasen.

Country Status (10)

Country Link
US (1) US5059535A (de)
EP (1) EP0470969B1 (de)
JP (1) JPH05500154A (de)
AT (1) ATE92523T1 (de)
AU (1) AU633912B2 (de)
CA (1) CA2051374C (de)
DE (1) DE69002623T2 (de)
DK (1) DK0470969T3 (de)
ES (1) ES2058908T3 (de)
WO (1) WO1990012090A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5079353A (en) * 1987-12-02 1992-01-07 Chembiomed, Ltd. Sialic acid glycosides, antigens, immunoadsorbents, and methods for their preparation
DE4009630C2 (de) * 1990-03-26 1995-09-28 Reinhard Prof Dr Dr Brossmer CMP-aktivierte fluoreszierende Sialinsäuren sowie Verfahren zu ihrer Herstellung
WO1992022563A1 (en) * 1991-06-10 1992-12-23 Alberta Research Council Modified sialyl lewisa compounds
US5646123A (en) * 1991-06-10 1997-07-08 Alberta Research Council Time dependent administration of oligosaccharide glycosides related to blood group determinants having a type I or type II core structure in reducing inflammation in a sensitized mammal arising form exposure to an antigen
US5374655A (en) * 1991-06-10 1994-12-20 Alberta Research Council Methods for the synthesis of monofucosylated oligosaccharides terminating in di-N-acetyllactosaminyl structures
US5352670A (en) * 1991-06-10 1994-10-04 Alberta Research Council Methods for the enzymatic synthesis of alpha-sialylated oligosaccharide glycosides
WO1992022565A1 (en) * 1991-06-10 1992-12-23 Alberta Research Council Modified sialyl lewisx compounds
SK108894A3 (en) * 1992-03-09 1995-07-11 Univ California Sialyltransferases and isolated dna fraction coding sialyltransferases
US5854042A (en) * 1993-12-24 1998-12-29 The Institute Of Physical And Chemical Research Sugar-chain synthetase and process for producing the same
US7214660B2 (en) 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
WO2004099231A2 (en) 2003-04-09 2004-11-18 Neose Technologies, Inc. Glycopegylation methods and proteins/peptides produced by the methods
WO2005012484A2 (en) 2003-07-25 2005-02-10 Neose Technologies, Inc. Antibody-toxin conjugates
US20080305992A1 (en) 2003-11-24 2008-12-11 Neose Technologies, Inc. Glycopegylated erythropoietin
EP1814573B1 (de) 2004-10-29 2016-03-09 ratiopharm GmbH Remodellierung und glykopegylierung von fibroblasten-wachstumsfaktor (fgf)
CA2593682C (en) 2005-01-10 2016-03-22 Neose Technologies, Inc. Glycopegylated granulocyte colony stimulating factor
US9187546B2 (en) 2005-04-08 2015-11-17 Novo Nordisk A/S Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
US20070105755A1 (en) 2005-10-26 2007-05-10 Neose Technologies, Inc. One pot desialylation and glycopegylation of therapeutic peptides
WO2007056191A2 (en) 2005-11-03 2007-05-18 Neose Technologies, Inc. Nucleotide sugar purification using membranes
JP2009544327A (ja) 2006-07-21 2009-12-17 ノヴォ ノルディスク アー／エス Ｏ−結合型グリコシル化配列によるペプチドのグリコシル化
EP2054521A4 (de) 2006-10-03 2012-12-19 Novo Nordisk As Verfahren zur reinigung von polypeptid-konjugate
KR20150064246A (ko) 2007-04-03 2015-06-10 바이오제너릭스 게엠베하 글리코페길화 ｇ―ｃｓｆ를 이용하는 치료 방법
ES2551123T3 (es) 2007-06-12 2015-11-16 Ratiopharm Gmbh Proceso mejorado para la producción de azúcares de nucleótido
DE102008005159B4 (de) 2008-01-18 2018-02-15 Robert Bosch Gmbh Verfahren und Steuergerät zur Ansteuerung von Personenschutzmittel für ein Fahrzeug
CN101965200B (zh) 2008-02-27 2013-06-19 诺沃-诺迪斯克有限公司 缀合的因子ⅷ分子

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4250262A (en) * 1979-12-14 1981-02-10 Forsyth Dental Infirmary For Children Method of preparing a purified glucosyltransferase
JPS58209980A (ja) * 1982-04-27 1983-12-07 Kyowa Hakko Kogyo Co Ltd 酵素の精製法
ATE37984T1 (de) * 1983-03-01 1988-11-15 Crc Ricerca Chim Pharmazeutische zusammensetzung welche 5acetamido-3,5-dideoxy-d-glycero-dgalactononulosamins|ure cytidin monophosphat enthaelt.
US4925796A (en) * 1986-03-07 1990-05-15 Massachusetts Institute Of Technology Method for enhancing glycoprotein stability

Also Published As

Publication number Publication date
ES2058908T3 (es) 1994-11-01
US5059535A (en) 1991-10-22
AU5528990A (en) 1990-11-05
EP0470969B1 (de) 1993-08-04
ATE92523T1 (de) 1993-08-15
WO1990012090A1 (en) 1990-10-18
DE69002623T2 (de) 1993-11-25
CA2051374C (en) 1996-02-27
AU633912B2 (en) 1993-02-11
JPH05500154A (ja) 1993-01-21
CA2051374A1 (en) 1990-10-13
DK0470969T3 (da) 1994-01-03
EP0470969A1 (de) 1992-02-19

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee