ATE92523T1 - Verfahren zur abtrennung und reinigung von sialyl-transferasen. - Google Patents

Verfahren zur abtrennung und reinigung von sialyl-transferasen.

Info

Publication number
ATE92523T1
ATE92523T1 AT90906090T AT90906090T ATE92523T1 AT E92523 T1 ATE92523 T1 AT E92523T1 AT 90906090 T AT90906090 T AT 90906090T AT 90906090 T AT90906090 T AT 90906090T AT E92523 T1 ATE92523 T1 AT E92523T1
Authority
AT
Austria
Prior art keywords
specific
sialyl
methods
lases
purification
Prior art date
Application number
AT90906090T
Other languages
English (en)
Inventor
M Abdul Mazid
Mohammed A Kashem
Original Assignee
Chembiomed Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chembiomed Ltd filed Critical Chembiomed Ltd
Application granted granted Critical
Publication of ATE92523T1 publication Critical patent/ATE92523T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/803—Physical recovery methods, e.g. chromatography, grinding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y10S435/815—Enzyme separation or purification by sorption

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
AT90906090T 1989-04-12 1990-04-12 Verfahren zur abtrennung und reinigung von sialyl-transferasen. ATE92523T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/336,932 US5059535A (en) 1989-04-12 1989-04-12 Process for the separation and purification of sialyl transferases
PCT/CA1990/000124 WO1990012090A1 (en) 1989-04-12 1990-04-12 Process for the separation and purification of sialyl transferases

Publications (1)

Publication Number Publication Date
ATE92523T1 true ATE92523T1 (de) 1993-08-15

Family

ID=23318345

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90906090T ATE92523T1 (de) 1989-04-12 1990-04-12 Verfahren zur abtrennung und reinigung von sialyl-transferasen.

Country Status (10)

Country Link
US (1) US5059535A (de)
EP (1) EP0470969B1 (de)
JP (1) JPH05500154A (de)
AT (1) ATE92523T1 (de)
AU (1) AU633912B2 (de)
CA (1) CA2051374C (de)
DE (1) DE69002623T2 (de)
DK (1) DK0470969T3 (de)
ES (1) ES2058908T3 (de)
WO (1) WO1990012090A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5079353A (en) * 1987-12-02 1992-01-07 Chembiomed, Ltd. Sialic acid glycosides, antigens, immunoadsorbents, and methods for their preparation
DE4009630C2 (de) * 1990-03-26 1995-09-28 Reinhard Prof Dr Dr Brossmer CMP-aktivierte fluoreszierende Sialinsäuren sowie Verfahren zu ihrer Herstellung
US5374655A (en) * 1991-06-10 1994-12-20 Alberta Research Council Methods for the synthesis of monofucosylated oligosaccharides terminating in di-N-acetyllactosaminyl structures
EP0589951A1 (de) * 1991-06-10 1994-04-06 Glycomed Incorporated Modifizierte Sialyl Lewis X-Verbindungen
JPH06510745A (ja) * 1991-06-10 1994-12-01 グライカムド　インコーポレイテッド 修飾シアリルルイスａ化合物
US5352670A (en) * 1991-06-10 1994-10-04 Alberta Research Council Methods for the enzymatic synthesis of alpha-sialylated oligosaccharide glycosides
US5646123A (en) * 1991-06-10 1997-07-08 Alberta Research Council Time dependent administration of oligosaccharide glycosides related to blood group determinants having a type I or type II core structure in reducing inflammation in a sensitized mammal arising form exposure to an antigen
ATE228565T1 (de) * 1992-03-09 2002-12-15 Univ California Nukleinsäure, expressionsvektor und zusammensetzungen zur identifizierung und herstellung von rekombinanten sialyltransferasen
WO1995018217A1 (en) 1993-12-24 1995-07-06 The Institute Of Physical And Chemical Research Novel sugar-chain synthetase and process for producing the same
US7214660B2 (en) 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
CA2522345A1 (en) 2003-04-09 2004-11-18 Neose Technologies, Inc. Glycopegylation methods and proteins/peptides produced by the methods
WO2005012484A2 (en) 2003-07-25 2005-02-10 Neose Technologies, Inc. Antibody-toxin conjugates
US20080305992A1 (en) 2003-11-24 2008-12-11 Neose Technologies, Inc. Glycopegylated erythropoietin
EP1814573B1 (de) 2004-10-29 2016-03-09 ratiopharm GmbH Remodellierung und glykopegylierung von fibroblasten-wachstumsfaktor (fgf)
CA2593682C (en) 2005-01-10 2016-03-22 Neose Technologies, Inc. Glycopegylated granulocyte colony stimulating factor
US9187546B2 (en) 2005-04-08 2015-11-17 Novo Nordisk A/S Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
US20070105755A1 (en) 2005-10-26 2007-05-10 Neose Technologies, Inc. One pot desialylation and glycopegylation of therapeutic peptides
US20090048440A1 (en) 2005-11-03 2009-02-19 Neose Technologies, Inc. Nucleotide Sugar Purification Using Membranes
CN101516388B (zh) 2006-07-21 2012-10-31 诺和诺德公司 通过o-联糖基化序列的肽的糖基化
US8969532B2 (en) 2006-10-03 2015-03-03 Novo Nordisk A/S Methods for the purification of polypeptide conjugates comprising polyalkylene oxide using hydrophobic interaction chromatography
EP2144923B1 (de) 2007-04-03 2013-02-13 BioGeneriX AG Behandlungsverfahren mit glycopegyliertem g-csf
WO2008154639A2 (en) 2007-06-12 2008-12-18 Neose Technologies, Inc. Improved process for the production of nucleotide sugars
DE102008005159B4 (de) 2008-01-18 2018-02-15 Robert Bosch Gmbh Verfahren und Steuergerät zur Ansteuerung von Personenschutzmittel für ein Fahrzeug
US20130189239A1 (en) 2008-02-27 2013-07-25 Novo Nordisk A/S Conjugated Factor VIII Molecules
EP3500244B1 (de) * 2016-08-22 2026-07-08 Lonza Sales AG Verfahren zur unterdrückung der abgabe von exosomen an die leber und die milz
AU2021314104A1 (en) * 2020-07-20 2023-01-19 Insmed, Inc. Methods for extracting neutrophil serine proteases and treating dipeptidyl peptidase 1-mediated conditions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4250262A (en) * 1979-12-14 1981-02-10 Forsyth Dental Infirmary For Children Method of preparing a purified glucosyltransferase
JPS58209980A (ja) * 1982-04-27 1983-12-07 Kyowa Hakko Kogyo Co Ltd 酵素の精製法
ATE37984T1 (de) * 1983-03-01 1988-11-15 Crc Ricerca Chim Pharmazeutische zusammensetzung welche 5acetamido-3,5-dideoxy-d-glycero-dgalactononulosamins|ure cytidin monophosphat enthaelt.
US4925796A (en) * 1986-03-07 1990-05-15 Massachusetts Institute Of Technology Method for enhancing glycoprotein stability

Also Published As

Publication number Publication date
AU633912B2 (en) 1993-02-11
CA2051374A1 (en) 1990-10-13
DE69002623T2 (de) 1993-11-25
DE69002623D1 (de) 1993-09-09
EP0470969A1 (de) 1992-02-19
DK0470969T3 (da) 1994-01-03
ES2058908T3 (es) 1994-11-01
EP0470969B1 (de) 1993-08-04
CA2051374C (en) 1996-02-27
WO1990012090A1 (en) 1990-10-18
US5059535A (en) 1991-10-22
JPH05500154A (ja) 1993-01-21
AU5528990A (en) 1990-11-05

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Legal Events

Date Code Title Description
EEIH Change in the person of patent owner
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee