BR9206313A - Anticorpos recombinantes para terapia humana. - Google Patents

Anticorpos recombinantes para terapia humana.

Info

Publication number
BR9206313A
BR9206313A BR9206313A BR9206313A BR9206313A BR 9206313 A BR9206313 A BR 9206313A BR 9206313 A BR9206313 A BR 9206313A BR 9206313 A BR9206313 A BR 9206313A BR 9206313 A BR9206313 A BR 9206313A
Authority
BR
Brazil
Prior art keywords
recombinant antibodies
human therapy
therapy
human
recombinant
Prior art date
Application number
BR9206313A
Other languages
English (en)
Inventor
Roland A Newman
Nabil Hanna
Ronald W Raab
Original Assignee
Idec Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27112830&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9206313(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Idec Pharma Corp filed Critical Idec Pharma Corp
Publication of BR9206313A publication Critical patent/BR9206313A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2812Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2821Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • C07K16/461Igs containing Ig-regions, -domains or -residues form different species
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • C07K16/461Igs containing Ig-regions, -domains or -residues form different species
    • C07K16/462Igs containing a variable region (Fv) from one specie and a constant region (Fc) from another
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
BR9206313A 1991-07-25 1992-07-24 Anticorpos recombinantes para terapia humana. BR9206313A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US73506491A 1991-07-25 1991-07-25
US85628192A 1992-03-23 1992-03-23
PCT/US1992/006194 WO1993002108A1 (en) 1991-07-25 1992-07-24 Recombinant antibodies for human therapy

Publications (1)

Publication Number Publication Date
BR9206313A true BR9206313A (pt) 1995-04-11

Family

ID=27112830

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9206313A BR9206313A (pt) 1991-07-25 1992-07-24 Anticorpos recombinantes para terapia humana.

Country Status (24)

Country Link
EP (3) EP0605442B1 (pt)
JP (1) JP3048640B2 (pt)
KR (1) KR0137806B1 (pt)
AP (1) AP307A (pt)
AT (2) ATE237638T1 (pt)
AU (1) AU673499B2 (pt)
BG (1) BG62656B1 (pt)
BR (1) BR9206313A (pt)
CA (1) CA2114015C (pt)
CZ (1) CZ289472B6 (pt)
DE (2) DE69233628T2 (pt)
DK (2) DK1266965T3 (pt)
ES (2) ES2265005T3 (pt)
FI (1) FI117703B (pt)
HU (2) HUT70272A (pt)
IL (1) IL102640A0 (pt)
MY (1) MY121185A (pt)
NO (1) NO318097B1 (pt)
NZ (1) NZ243706A (pt)
OA (1) OA09879A (pt)
PT (1) PT100735B (pt)
RO (1) RO116404B1 (pt)
SK (2) SK285960B6 (pt)
WO (1) WO1993002108A1 (pt)

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US6277969B1 (en) 1991-03-18 2001-08-21 New York University Anti-TNF antibodies and peptides of human tumor necrosis factor
US5919452A (en) * 1991-03-18 1999-07-06 New York University Methods of treating TNFα-mediated disease using chimeric anti-TNF antibodies
DE69233104T2 (de) * 1991-07-15 2004-05-13 The Wellcome Foundation Ltd., Greenford Herstellung von Antikörpern
US6136310A (en) * 1991-07-25 2000-10-24 Idec Pharmaceuticals Corporation Recombinant anti-CD4 antibodies for human therapy
US7744877B2 (en) 1992-11-13 2010-06-29 Biogen Idec Inc. Expression and use of anti-CD20 Antibodies
DE69329503T2 (de) 1992-11-13 2001-05-03 Idec Pharma Corp Therapeutische Verwendung von chimerischen und markierten Antikörpern, die gegen ein Differenzierung-Antigen gerichtet sind, dessen Expression auf menschliche B Lymphozyt beschränkt ist, für die Behandlung von B-Zell-Lymphoma
RU2139092C1 (ru) 1993-06-03 1999-10-10 Терапьютик Антибодиз Инк. Фрагменты антител в терапии
US5429746A (en) 1994-02-22 1995-07-04 Smith Kline Beecham Corporation Antibody purification
ATE195428T1 (de) * 1994-04-26 2000-09-15 Kanebo Ltd Arznei für rheumatoide arthritis
DE69519997T2 (de) * 1994-10-25 2001-06-21 Glaxo Group Ltd., Greenford Verwendung von bindungsreagenzien gegen cd23 in der behandlung von autoimmunkrankheiten
CA2206471A1 (en) * 1994-12-07 1996-06-13 Hoffmann-La Roche Inc. Monoclonal antibody fragments having immunosuppressant activity
US6113898A (en) 1995-06-07 2000-09-05 Idec Pharmaceuticals Corporation Human B7.1-specific primatized antibodies and transfectomas expressing said antibodies
US7153508B2 (en) 1995-06-07 2006-12-26 Biogen Idec Inc. Treatment of B cell lymphoma using anti-CD80 antibodies that do not inhibit the binding of CD80 to CTLA-4
US7175847B1 (en) 1995-06-07 2007-02-13 Biogen Idec Inc. Treating intestinal inflammation with anti-CD80 antibodies that do not inhibit CD80 binding to CTLA-4
GB9624038D0 (en) * 1996-11-19 1997-01-08 Sandoz Ltd Organic compounds
US6011138A (en) * 1997-02-20 2000-01-04 Idec Pharmaceuticals Corporation Gamma-1 anti-human CD23 monoclonal antibodies
US6893636B2 (en) 1997-02-20 2005-05-17 Biogen Idec Ma Inc. Gamma-1 and gamma-3 anti-human CD23 monoclonal antibodies and use thereof as therapeutics
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JP2002512776A (ja) * 1998-04-28 2002-05-08 スミスクライン・ビーチャム・コーポレイション 免疫原性の低下したモノクローナル抗体
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EP2990054A1 (en) 1998-08-11 2016-03-02 Biogen Inc. Combination therapies for B-cell lyphomas comprising administration of anti-CD20 antibody
PT2055313E (pt) 1998-11-09 2015-08-25 Biogen Idec Inc Tratamento de malignidades hematológicas associadas a células tumorais em circulação utilizando anticorpo quimérico anti-cd20
ATE311199T1 (de) 1999-05-07 2005-12-15 Genentech Inc Behandlung von autoimmunkrankheiten mit antagonisten die oberflächenmarker von b zellen binden
US8557244B1 (en) 1999-08-11 2013-10-15 Biogen Idec Inc. Treatment of aggressive non-Hodgkins lymphoma with anti-CD20 antibody
AU2001271614B2 (en) * 2000-07-03 2007-05-31 Catalent Pharma Solutions, Llc Host cells containing multiple integrating vectors
ES2389141T3 (es) * 2000-07-03 2012-10-23 Catalent Pharma Solutions, Llc Células huésped que contienen vectores de integración múltiple
AU7025201A (en) 2000-07-03 2002-01-14 Gala Design Inc Expression vectors
UA81743C2 (uk) 2000-08-07 2008-02-11 Центокор, Инк. МОНОКЛОНАЛЬНЕ АНТИТІЛО ЛЮДИНИ, ЩО СПЕЦИФІЧНО ЗВ'ЯЗУЄТЬСЯ З ФАКТОРОМ НЕКРОЗУ ПУХЛИН АЛЬФА (ФНПα), ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ, ЩО ЙОГО МІСТИТЬ, ТА СПОСІБ ЛІКУВАННЯ РЕВМАТОЇДНОГО АРТРИТУ
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KR102188544B1 (ko) 2010-11-30 2020-12-08 제넨테크, 인크. 저친화도 혈액-뇌 장벽 수용체 항체 및 그의 용도
US10894087B2 (en) 2010-12-22 2021-01-19 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds
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Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69233104T2 (de) * 1991-07-15 2004-05-13 The Wellcome Foundation Ltd., Greenford Herstellung von Antikörpern

Also Published As

Publication number Publication date
CA2114015C (en) 2002-12-10
PT100735A (pt) 1993-10-29
DE69233011T2 (de) 2003-11-06
SK8894A3 (en) 1994-09-07
KR0137806B1 (ko) 1998-04-30
BG62656B1 (bg) 2000-04-28
ATE237638T1 (de) 2003-05-15
ES2196002T3 (es) 2003-12-16
EP0605442B1 (en) 2003-04-16
CZ14994A3 (en) 1994-07-13
EP1266965A2 (en) 2002-12-18
MY121185A (en) 2006-01-28
SK285960B6 (sk) 2007-12-06
AU673499B2 (en) 1996-11-14
NO940219D0 (no) 1994-01-21
SK285046B6 (sk) 2006-05-04
NO318097B1 (no) 2005-01-31
JP3048640B2 (ja) 2000-06-05
NO940219L (no) 1994-03-25
AU2425592A (en) 1993-02-23
EP1266965B1 (en) 2006-05-24
DK0605442T3 (da) 2003-08-04
ES2265005T3 (es) 2007-02-01
AP307A (en) 1994-01-31
HU9400201D0 (en) 1994-05-30
HU211881A9 (en) 1995-12-28
DE69233628D1 (de) 2006-06-29
EP1715045A2 (en) 2006-10-25
EP0605442A4 (en) 1995-07-12
HUT70272A (en) 1995-09-28
RO116404B1 (ro) 2001-01-30
CZ289472B6 (cs) 2002-01-16
DK1266965T3 (da) 2006-09-25
OA09879A (en) 1994-09-15
WO1993002108A1 (en) 1993-02-04
NZ243706A (en) 1994-08-26
EP1715045A3 (en) 2006-12-13
DE69233011D1 (de) 2003-05-22
EP0605442A1 (en) 1994-07-13
EP1266965A3 (en) 2003-01-02
IL102640A0 (en) 1993-01-14
FI940336A0 (fi) 1994-01-24
FI117703B (fi) 2007-01-31
ATE327331T1 (de) 2006-06-15
FI940336A (fi) 1994-03-10
DE69233628T2 (de) 2007-04-26
BG98411A (bg) 1995-02-28
CA2114015A1 (en) 1993-02-04
AP9200413A0 (en) 1992-07-31
PT100735B (pt) 1999-07-30
JPH06509708A (ja) 1994-11-02

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EG Technical examination (opinion): publication of technical examination (opinion)
HIFC Refusal cancelled
FC Decision: refusal
CKFC Appeal: appeal against refusal
B15K Others concerning applications: alteration of classification

Ipc: C07K 16/18 (2006.01), C07K 16/00 (2006.0