BR112022019124A2 - Composições e métodos para liberação de rna - Google Patents
Composições e métodos para liberação de rnaInfo
- Publication number
- BR112022019124A2 BR112022019124A2 BR112022019124A BR112022019124A BR112022019124A2 BR 112022019124 A2 BR112022019124 A2 BR 112022019124A2 BR 112022019124 A BR112022019124 A BR 112022019124A BR 112022019124 A BR112022019124 A BR 112022019124A BR 112022019124 A2 BR112022019124 A2 BR 112022019124A2
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- compositions
- release
- rna release
- rna
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 4
- 239000007908 nanoemulsion Substances 0.000 abstract 2
- 239000002105 nanoparticle Substances 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 239000012867 bioactive agent Substances 0.000 abstract 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- 238000003384 imaging method Methods 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 238000002255 vaccination Methods 0.000 abstract 1
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
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Abstract
COMPOSIÇÕES E MÉTODOS PARA LIBERAÇÃO DE RNA. A divulgação fornece composições de nanoemulsão e métodos de preparação e uso das mesmas para liberar um agente bioativo, tal como um ácido nucleico, a um indivíduo. A composição de nanoemulsão compreende um núcleo hidrofóbico baseado em nanopartículas inorgânicas em uma nanopartícula lipídica que permite a formação de imagem, bem como a liberação de ácidos nucleicos. Métodos de uso dessas partículas para tratamento e vacinação também são fornecidos.
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US202062993307P | 2020-03-23 | 2020-03-23 | |
US202063054754P | 2020-07-21 | 2020-07-21 | |
PCT/US2021/019103 WO2021194672A1 (en) | 2020-03-23 | 2021-02-22 | Compositions and methods for delivery of rna |
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BR112022019124A2 true BR112022019124A2 (pt) | 2023-02-14 |
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CA (1) | CA3172489A1 (pt) |
GB (2) | GB2605312B (pt) |
WO (1) | WO2021194672A1 (pt) |
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