BR112021014805A2 - Métodos de produção para uma proteína recombinante e para aumentar o volume de produção - Google Patents
Métodos de produção para uma proteína recombinante e para aumentar o volume de produçãoInfo
- Publication number
- BR112021014805A2 BR112021014805A2 BR112021014805A BR112021014805A BR112021014805A2 BR 112021014805 A2 BR112021014805 A2 BR 112021014805A2 BR 112021014805 A BR112021014805 A BR 112021014805A BR 112021014805 A BR112021014805 A BR 112021014805A BR 112021014805 A2 BR112021014805 A2 BR 112021014805A2
- Authority
- BR
- Brazil
- Prior art keywords
- recombinant protein
- recombinant
- production
- recombinant cells
- protein
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 6
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 title abstract 5
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 title abstract 5
- 230000004663 cell proliferation Effects 0.000 abstract 3
- 230000035755 proliferation Effects 0.000 abstract 2
- 230000019552 anatomical structure morphogenesis Effects 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
- C07K14/43518—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from spiders
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Insects & Arthropods (AREA)
- Mycology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019015716 | 2019-01-31 | ||
| JP2019142388 | 2019-08-01 | ||
| PCT/JP2020/003487 WO2020158877A1 (ja) | 2019-01-31 | 2020-01-30 | 組換えタンパク質の製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112021014805A2 true BR112021014805A2 (pt) | 2022-01-04 |
Family
ID=71840352
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112021014805A BR112021014805A2 (pt) | 2019-01-31 | 2020-01-30 | Métodos de produção para uma proteína recombinante e para aumentar o volume de produção |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20220033870A1 (https=) |
| EP (1) | EP3919506A4 (https=) |
| JP (2) | JP6968468B2 (https=) |
| CN (1) | CN113439087A (https=) |
| BR (1) | BR112021014805A2 (https=) |
| CA (1) | CA3127177A1 (https=) |
| SG (1) | SG11202107697UA (https=) |
| WO (1) | WO2020158877A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021020546A1 (ja) * | 2019-08-01 | 2021-02-04 | Ｓｐｉｂｅｒ株式会社 | 組換え細胞及び組換えタンパク質の製造方法 |
| MX2024010846A (es) * | 2022-03-24 | 2024-09-11 | Richter Gedeon Nyrt | Metodo para la preparacion de biofarmacos. |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58110600A (ja) | 1981-12-25 | 1983-07-01 | Kyowa Hakko Kogyo Co Ltd | ヒトβ型インタ−フエロン遺伝子を含む組みかえ体プラスミド |
| JPS60221091A (ja) | 1983-12-21 | 1985-11-05 | Kyowa Hakko Kogyo Co Ltd | 新規プロモ−タ− |
| JP2564268B2 (ja) | 1985-08-28 | 1996-12-18 | 協和醗酵工業株式会社 | 融合抗原ポリペプチド |
| JP2545078B2 (ja) | 1987-04-06 | 1996-10-16 | 協和醗酵工業株式会社 | 核酸関連物質の製造法 |
| EP0326046A3 (en) | 1988-01-25 | 1990-06-13 | Takeda Chemical Industries, Ltd. | Production of human epidermal growth factor |
| JPH0322979A (ja) | 1989-06-19 | 1991-01-31 | Kyowa Hakko Kogyo Co Ltd | 新規プラスミノーゲン活性化因子 |
| JP3012026B2 (ja) | 1991-03-05 | 2000-02-21 | ヒゲタ醤油株式会社 | 高発現ベクター及び該高発現ベクター を保有する微生物並びに該微生物を 用いる有用物質の製造法 |
| JP3433807B2 (ja) | 1992-03-31 | 2003-08-04 | 鵜高 重三 | 新規アミノ酸配列及び該アミノ酸配列をコードするｄｎａを保有する発現ベクターを組み込んだバチルス・ブレビスを用いる有用物質の製造法 |
| JP2727391B2 (ja) | 1992-07-23 | 1998-03-11 | ヒゲタ醤油株式会社 | 高発現ベクター及び該高発現ベクターを保有する微生物並びに該微生物を用いる有用物質の製造法 |
| JP2771756B2 (ja) | 1993-04-09 | 1998-07-02 | 東洋エンジニアリング株式会社 | 組換え大腸菌の培養方法 |
| JP2002535007A (ja) * | 1999-01-27 | 2002-10-22 | エリトラ ファーマシューティカルズ，インコーポレイテッド | Ｅｓｃｈｅｒｉｃｈｉａｃｏｌｉの増殖に必要であると同定された遺伝子 |
| JP3753945B2 (ja) | 2001-02-14 | 2006-03-08 | ヒゲタ醤油株式会社 | 大腸菌とブレビバチルス属細菌間のプラスミドシャトルベクター |
| CN101712955B (zh) * | 2002-03-06 | 2013-06-05 | 东丽株式会社 | 利用基因重组蚕生产生理活性蛋白质的方法 |
| KR100499647B1 (ko) * | 2002-09-25 | 2005-07-05 | 한국과학기술원 | 박테리아에서의 외래단백질의 생산성을 증가시키는 방법 |
| AU2007250735A1 (en) * | 2006-05-16 | 2007-11-22 | Daiichi Sankyo Company, Limited | Method for high-level secretory production of protein |
| BRPI0701826B1 (pt) * | 2007-03-16 | 2021-02-17 | Embrapa - Empresa Brasileira De Pesquisa Agropecuária | proteínas da teia de aranha nephilengys cruentata, avicularia juruensis e parawixia bistriata isoladas da biodiversidade brasileira |
| WO2015178466A1 (ja) * | 2014-05-21 | 2015-11-26 | 味の素株式会社 | フィブロイン様タンパク質の製造法 |
| CN105331568B (zh) * | 2014-06-12 | 2019-01-04 | 清华大学 | 一种通过增大细菌体积而增加微生物胞内内含物积累量的方法 |
| JP7452830B2 (ja) * | 2016-08-02 | 2024-03-19 | Ｓｐｉｂｅｒ株式会社 | 組換えタンパク質の生産方法 |
-
2020
- 2020-01-30 SG SG11202107697UA patent/SG11202107697UA/en unknown
- 2020-01-30 CA CA3127177A patent/CA3127177A1/en active Pending
- 2020-01-30 CN CN202080011556.4A patent/CN113439087A/zh active Pending
- 2020-01-30 US US17/426,610 patent/US20220033870A1/en active Pending
- 2020-01-30 EP EP20749538.3A patent/EP3919506A4/en active Pending
- 2020-01-30 WO PCT/JP2020/003487 patent/WO2020158877A1/ja not_active Ceased
- 2020-01-30 BR BR112021014805A patent/BR112021014805A2/pt unknown
- 2020-01-30 JP JP2020560429A patent/JP6968468B2/ja active Active
-
2021
- 2021-04-15 JP JP2021069163A patent/JP7526489B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| SG11202107697UA (en) | 2021-08-30 |
| EP3919506A1 (en) | 2021-12-08 |
| CA3127177A1 (en) | 2020-08-06 |
| US20220033870A1 (en) | 2022-02-03 |
| JP2021101744A (ja) | 2021-07-15 |
| JP6968468B2 (ja) | 2021-11-17 |
| EP3919506A4 (en) | 2022-11-02 |
| WO2020158877A1 (ja) | 2020-08-06 |
| CN113439087A (zh) | 2021-09-24 |
| JPWO2020158877A1 (ja) | 2021-02-18 |
| JP7526489B2 (ja) | 2024-08-01 |
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