BR112021008930A2 - Métodos e combinações para o tratamento e modulação de célula t - Google Patents
Métodos e combinações para o tratamento e modulação de célula tInfo
- Publication number
- BR112021008930A2 BR112021008930A2 BR112021008930A BR112021008930A BR112021008930A2 BR 112021008930 A2 BR112021008930 A2 BR 112021008930A2 BR 112021008930 A BR112021008930 A BR 112021008930A BR 112021008930 A BR112021008930 A BR 112021008930A BR 112021008930 A2 BR112021008930 A2 BR 112021008930A2
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- cells
- cell therapy
- compositions
- involving
- Prior art date
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862757755P | 2018-11-08 | 2018-11-08 | |
| US201962826928P | 2019-03-29 | 2019-03-29 | |
| PCT/US2019/060367 WO2020097403A1 (en) | 2018-11-08 | 2019-11-07 | Methods and combinations for treatment and t cell modulation |
Publications (1)
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| MA54078A (fr) | 2018-11-01 | 2021-09-15 | Juno Therapeutics Inc | Méthodes pour le traitement au moyen de récepteurs antigéniques chimériques spécifiques de l'antigene de maturation des lymphocytes b |
| CA3117978A1 (en) * | 2018-11-08 | 2020-05-14 | Juno Therapeutics, Inc. | Methods and combinations for treatment and t cell modulation |
| AR119715A1 (es) | 2019-04-12 | 2022-01-05 | Celgene Corp | Métodos para tratar linfoma no hodgkin con el uso de 2-(2,6-dioxopiperidin-3-il)-4-((2-fluoro-4-((3-morfolinoazetidin-1-il)metil)bencil)amino)isoindolin-1,3-diona |
| WO2021091978A1 (en) | 2019-11-05 | 2021-05-14 | Celgene Corporation | Uses of anti-bcma chimeric antigen receptors |
| IL292667B1 (en) | 2019-11-07 | 2026-02-01 | Juno Therapeutics Inc | Combination of T-cell therapy and (s)-3-[4-(4-morpholin-4-ylmethyl-benzyloxy)-l-oxo-3,l-dihydro-isoindol-2-yl]-piperidine-6,2-dione |
| US20230165872A1 (en) | 2020-04-28 | 2023-06-01 | Juno Therapeutics, Inc. | Combination of bcma-directed t cell therapy and an immunomodulatory compound |
| MX2023011370A (es) | 2021-03-29 | 2023-11-24 | Juno Therapeutics Inc | Combinacion de una terapia con celulas t con receptores de antigenos quimericos (car) y un compuesto inmunomodulador para el tratamiento de linfoma. |
| CN118201618A (zh) | 2021-04-16 | 2024-06-14 | 细胞基因公司 | 与bcma定向t细胞疗法的组合疗法 |
-
2019
- 2019-11-07 CA CA3117978A patent/CA3117978A1/en active Pending
- 2019-11-07 CN CN201980088003.6A patent/CN113573719A/zh active Pending
- 2019-11-07 WO PCT/US2019/060367 patent/WO2020097403A1/en not_active Ceased
- 2019-11-07 SG SG11202104411VA patent/SG11202104411VA/en unknown
- 2019-11-07 BR BR112021008930A patent/BR112021008930A2/pt unknown
- 2019-11-07 EP EP19842432.7A patent/EP3876958A1/en active Pending
- 2019-11-07 IL IL282886A patent/IL282886B2/en unknown
- 2019-11-07 JP JP2021525078A patent/JP2022512971A/ja active Pending
- 2019-11-07 MX MX2021005366A patent/MX2021005366A/es unknown
- 2019-11-07 AU AU2019377854A patent/AU2019377854A1/en active Pending
- 2019-11-07 KR KR1020217017475A patent/KR20210111247A/ko not_active Ceased
- 2019-11-07 US US17/292,363 patent/US12263190B2/en active Active
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2025
- 2025-02-28 US US19/067,506 patent/US20250186503A1/en active Pending
- 2025-03-03 JP JP2025032611A patent/JP2025087780A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| MX2021005366A (es) | 2021-09-10 |
| SG11202104411VA (en) | 2021-05-28 |
| IL282886A (en) | 2021-06-30 |
| IL282886B2 (en) | 2025-07-01 |
| IL282886B1 (en) | 2025-03-01 |
| EP3876958A1 (en) | 2021-09-15 |
| CN113573719A (zh) | 2021-10-29 |
| JP2022512971A (ja) | 2022-02-07 |
| AU2019377854A1 (en) | 2021-05-27 |
| US20250186503A1 (en) | 2025-06-12 |
| KR20210111247A (ko) | 2021-09-10 |
| US12263190B2 (en) | 2025-04-01 |
| JP2025087780A (ja) | 2025-06-10 |
| US20220008477A1 (en) | 2022-01-13 |
| WO2020097403A1 (en) | 2020-05-14 |
| CA3117978A1 (en) | 2020-05-14 |
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