BR112013033661A2 - inibidores de ativação de células t - Google Patents

inibidores de ativação de células t

Info

Publication number
BR112013033661A2
BR112013033661A2 BR112013033661A BR112013033661A BR112013033661A2 BR 112013033661 A2 BR112013033661 A2 BR 112013033661A2 BR 112013033661 A BR112013033661 A BR 112013033661A BR 112013033661 A BR112013033661 A BR 112013033661A BR 112013033661 A2 BR112013033661 A2 BR 112013033661A2
Authority
BR
Brazil
Prior art keywords
cell activation
activation inhibitors
specific binder
inhibitors
ctla
Prior art date
Application number
BR112013033661A
Other languages
English (en)
Inventor
Canwen Jiang
Jozsef Karman
Ronnie Wei
Seng Chen
Yunxiang Zhu
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47424568&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112013033661(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of BR112013033661A2 publication Critical patent/BR112013033661A2/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
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    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70532—B7 molecules, e.g. CD80, CD86
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70539—MHC-molecules, e.g. HLA-molecules
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
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  • Obesity (AREA)
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  • Pain & Pain Management (AREA)
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Abstract

resumo patente de invenção: "inibidores de ativação de células t". a presente invenção refere-se a um produto biológico biespecífico compreendendo um ligante específico para ctla-4 e um ligante específico para um complexo pmhc.
BR112013033661A 2011-06-30 2012-06-29 inibidores de ativação de células t BR112013033661A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161503282P 2011-06-30 2011-06-30
PCT/US2012/045017 WO2013003761A1 (en) 2011-06-30 2012-06-29 Inhibitors of t-cell activation

Publications (1)

Publication Number Publication Date
BR112013033661A2 true BR112013033661A2 (pt) 2017-01-24

Family

ID=47424568

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013033661A BR112013033661A2 (pt) 2011-06-30 2012-06-29 inibidores de ativação de células t

Country Status (34)

Country Link
US (3) US9834604B2 (pt)
EP (2) EP3357511B1 (pt)
JP (4) JP6157461B2 (pt)
KR (1) KR20140058532A (pt)
CN (2) CN103796681B (pt)
AU (3) AU2012275133B2 (pt)
BR (1) BR112013033661A2 (pt)
CA (1) CA2839462A1 (pt)
CL (1) CL2013003725A1 (pt)
CO (1) CO6841996A2 (pt)
CR (1) CR20130661A (pt)
DK (2) DK2726101T3 (pt)
DO (1) DOP2013000313A (pt)
ES (2) ES2694749T3 (pt)
GT (1) GT201300323A (pt)
HK (1) HK1258401A1 (pt)
HR (1) HRP20181786T1 (pt)
HU (1) HUE040455T2 (pt)
LT (1) LT2726101T (pt)
MA (1) MA35280B1 (pt)
MX (1) MX354922B (pt)
MY (1) MY180616A (pt)
NI (1) NI201300140A (pt)
PE (1) PE20141469A1 (pt)
PL (2) PL2726101T3 (pt)
PT (2) PT3357511T (pt)
RS (1) RS57996B1 (pt)
RU (1) RU2657440C2 (pt)
SG (1) SG10201604715VA (pt)
SI (1) SI2726101T1 (pt)
TN (1) TN2013000532A1 (pt)
UA (1) UA116191C2 (pt)
WO (1) WO2013003761A1 (pt)
ZA (1) ZA201309532B (pt)

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