BR112012023693A2 - Matriz de microagulha contendo proteoglicana - Google Patents

Matriz de microagulha contendo proteoglicana

Info

Publication number
BR112012023693A2
BR112012023693A2 BR112012023693A BR112012023693A BR112012023693A2 BR 112012023693 A2 BR112012023693 A2 BR 112012023693A2 BR 112012023693 A BR112012023693 A BR 112012023693A BR 112012023693 A BR112012023693 A BR 112012023693A BR 112012023693 A2 BR112012023693 A2 BR 112012023693A2
Authority
BR
Brazil
Prior art keywords
microneedle
skin
microneedle matrix
matrix containing
proteoglycan
Prior art date
Application number
BR112012023693A
Other languages
English (en)
Inventor
Quan Ying-Shu
Kamiyama Fumio
Taki Takao
Kawai Kazuyoshi
Takemoto Tadayoshi
Hamabuchi Takuya
Ohta Kazuhide
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of BR112012023693A2 publication Critical patent/BR112012023693A2/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/87—Application Devices; Containers; Packaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/91—Injection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053—Methods for producing microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Cosmetics (AREA)

Abstract

MATRIZ DE MICROAGULHA CONTENDO PROTEOGLICANA. A presente invenção refere-se a uma nova matriz de microagulha que tem (1) a resistência para suportar inserção na camada superficial da pele e/ou stratum comeum, (2) a fineza e flexibilidade para não causar dor ou sangramento na camada superficial da pele e/ou stratum comeum no local de inserção das microagulhas e (3) solubilidade ou biodegradabilidade das porções de microagulha sob a pele. A matriz microagulha é produzida mediante formação de microagulhas usando proteoglicana como um material de base.
BR112012023693A 2010-03-19 2011-03-18 Matriz de microagulha contendo proteoglicana BR112012023693A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2010065089 2010-03-19
PCT/JP2011/056643 WO2011115272A1 (ja) 2010-03-19 2011-03-18 プロテオグリカンを含有するマイクロニードルアレイ

Publications (1)

Publication Number Publication Date
BR112012023693A2 true BR112012023693A2 (pt) 2017-10-03

Family

ID=44649352

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012023693A BR112012023693A2 (pt) 2010-03-19 2011-03-18 Matriz de microagulha contendo proteoglicana

Country Status (17)

Country Link
US (1) US9539418B2 (pt)
EP (1) EP2548608B1 (pt)
JP (1) JP5800799B2 (pt)
KR (1) KR101813735B1 (pt)
CN (2) CN105107083B (pt)
AR (1) AR080778A1 (pt)
AU (1) AU2011228020A1 (pt)
BR (1) BR112012023693A2 (pt)
CA (1) CA2792927A1 (pt)
CO (1) CO6620002A2 (pt)
EA (1) EA201290928A1 (pt)
ES (1) ES2663095T3 (pt)
MX (1) MX2012010681A (pt)
NZ (1) NZ602692A (pt)
SG (1) SG183913A1 (pt)
TW (1) TW201138881A (pt)
WO (1) WO2011115272A1 (pt)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9149496B2 (en) 2007-05-10 2015-10-06 Cormatrix Cardiovascular, Inc. ECM Constructs for treating damaged biological tissue
JP5990913B2 (ja) * 2012-01-31 2016-09-14 凸版印刷株式会社 針状体の製造方法
ES2851234T3 (es) * 2012-09-13 2021-09-03 Avraham Amir Dispositivos de suministro y métodos para aumento cutáneo
US20150141910A1 (en) * 2013-11-14 2015-05-21 University Medical Pharmaceuticals Corporation Microneedles for therapeutic agent delivery with improved mechanical properties
WO2015108510A1 (en) * 2014-01-15 2015-07-23 Cormatrix Cardiovascular, Inc. Ecm constructs for treating damaged biological tissue
US20160279401A1 (en) 2015-03-27 2016-09-29 Allergan, Inc. Dissolvable microneedles for skin treatment
CN104888343A (zh) * 2015-05-07 2015-09-09 北京化工大学 一种高分子实心微针及其批量制备方法
CN104826228B (zh) * 2015-05-25 2017-12-29 成都凤磐生物科技有限公司 用于皮肤修复与保养的生物贴
US20170209553A1 (en) * 2016-01-22 2017-07-27 Transderm, Inc. Delivery of botulinum with microneedle arrays
JP2017145226A (ja) * 2016-02-19 2017-08-24 日本写真印刷株式会社 マイクロニードルシート
CN108883262B (zh) * 2016-03-25 2021-05-28 凸版印刷株式会社 经皮给药装置
US11241563B2 (en) 2016-12-22 2022-02-08 Johnson & Johnson Consumer Inc. Microneedle arrays and methods for making and using
WO2018151832A1 (en) 2017-02-17 2018-08-23 Allergan, Inc. Microneedle array with active ingredient
KR101993706B1 (ko) * 2017-06-13 2019-06-28 기 수 한 스탬프형 유체주입장치
KR20190005478A (ko) 2017-07-07 2019-01-16 경상대학교산학협력단 마이크로니들 디바이스
KR102139335B1 (ko) * 2017-11-24 2020-07-29 주식회사 엘지생활건강 니들 팁에 코팅부를 보유하는 마이크로니들을 제조하는 방법 및 장치
SG10201800072YA (en) * 2018-01-03 2019-08-27 Micropoint Tech Pte Ltd Microneedle Patches Comprising Corticosteroid
JP7476119B2 (ja) 2018-06-29 2024-04-30 ジョンソン アンド ジョンソン コンシューマー インコーポレイテッド 活性物質の送達のための三次元マイクロ流体デバイス
KR102075103B1 (ko) * 2018-09-28 2020-02-10 주식회사 코씨드바이오팜 홍어 발효 추출물을 유효성분으로 함유하는 화장료 조성물
CN109675185A (zh) * 2019-01-02 2019-04-26 浙江大学 一种苯硼酸水凝胶基糖敏微针贴及其制备方法
JP1664599S (pt) * 2019-09-19 2020-07-27
JP1664520S (pt) * 2019-09-19 2020-07-27
JP1664598S (pt) * 2019-09-19 2020-07-27
JP2021049141A (ja) * 2019-09-25 2021-04-01 富士フイルム株式会社 マイクロニードルアレイ、支持部材、マイクロニードルアレイの製造方法及びマイクロニードルアレイユニット
JP2021143146A (ja) * 2020-03-11 2021-09-24 コスメディ製薬株式会社 天然保湿因子含有貼付型化粧料
CN111939458A (zh) * 2020-08-25 2020-11-17 四川大学 一种具有超薄柔性背衬层的微针贴片及其制备方法
CN113197838B (zh) * 2021-03-31 2022-08-23 浙江大学 一种无酶糖敏微针贴及其温和制备方法
CN114366700B (zh) * 2022-01-19 2023-10-03 华工新颜(深圳)科技有限公司 一种祛眼袋的梅片龙脑香可溶性微针眼贴及其制备方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7799766B2 (en) 1998-04-08 2010-09-21 Theta Biomedical Consulting & Development Co., Inc. Composition for treating hormonally-dependent cancers
AU767122B2 (en) * 1998-06-10 2003-10-30 Georgia Tech Research Corporation Microneedle devices and methods of manufacture and use thereof
JP2001247602A (ja) * 2000-03-02 2001-09-11 Mitsuo Takai 鮭由来のコンドロイチン硫酸
JP2003299497A (ja) * 2002-02-05 2003-10-21 Masayoshi Kachi ムコ多糖類及びその製造方法
JP3756838B2 (ja) 2002-04-09 2006-03-15 日本メナード化粧品株式会社 皮膚外用剤
US7803787B2 (en) * 2002-10-16 2010-09-28 Arthrodynamic Technologies, Animal Health Division, Inc. Composition and method for treating connective tissue damage by transmucosal administration
KR20070100820A (ko) * 2005-01-31 2007-10-11 가부시키가이샤 바이오세렌택 경피 흡수 제제, 경피 흡수 제제 유지 시트 및 경피 흡수제제 유지 용구
EP1935438A4 (en) 2005-09-16 2011-10-19 St Marianna University School Of Medicine BIOMATERIAL FOR REGENERATIVE MEDICINE
JP2007131548A (ja) 2005-11-08 2007-05-31 Hirosaki Univ プロテオグリカンの新規医薬用途
RU2401839C2 (ru) * 2006-02-14 2010-10-20 Кусиро Индастриал Текнолоджи Сентер Способ получения протеогликана
US20090182306A1 (en) 2006-07-21 2009-07-16 Georgia Tech Research Corporation Microneedle Devices and Methods of Drug Delivery or Fluid Withdrawal
JPWO2008020632A1 (ja) * 2006-08-18 2010-01-07 凸版印刷株式会社 マイクロニードル及びマイクロニードルパッチ
EP2213284B1 (en) 2007-11-21 2017-11-15 BioSerenTach Co., Ltd. Preparation for application to body surface and preparation holding sheet for application to body surface
JP5252623B2 (ja) * 2008-01-22 2013-07-31 国立大学法人弘前大学 プロテオグリカンの抽出方法
JP5267910B2 (ja) 2008-02-28 2013-08-21 コスメディ製薬株式会社 マイクロニードルアレイ
EP2280720B1 (en) * 2008-03-27 2019-01-16 Purdue Research Foundation Collagen-binding synthetic peptidoglycans, preparation, and methods of use
JP2009254756A (ja) 2008-04-14 2009-11-05 Kosumedei Seiyaku Kk マイクロニードルアレイ
JP4427691B2 (ja) * 2008-04-14 2010-03-10 コスメディ製薬株式会社 マイクロニードルアレイ
JP2009254765A (ja) 2008-04-15 2009-11-05 Yoshisuke Watanabe 物干し装置
US9028463B2 (en) 2008-06-30 2015-05-12 Hisamitsu Pharmaceutical Co., Inc. Microneedle device, and method for enhancing the efficacy of influenza vaccine by using microneedle device
US8798933B2 (en) * 2008-10-31 2014-08-05 The Invention Science Fund I, Llc Frozen compositions and methods for piercing a substrate
JP2011012050A (ja) 2009-06-03 2011-01-20 Bioserentack Co Ltd 多孔性基盤を用いたマイクロニードル・アレイとその製造方法
EP2338557A1 (en) * 2009-12-23 2011-06-29 Debiotech S.A. Soluble microneedle

Also Published As

Publication number Publication date
EP2548608A4 (en) 2013-10-09
EA201290928A1 (ru) 2013-04-30
KR101813735B1 (ko) 2017-12-29
SG183913A1 (en) 2012-10-30
KR20130007615A (ko) 2013-01-18
TW201138881A (en) 2011-11-16
JPWO2011115272A1 (ja) 2013-07-04
US20130012882A1 (en) 2013-01-10
NZ602692A (en) 2013-12-20
JP5800799B2 (ja) 2015-10-28
AR080778A1 (es) 2012-05-09
CA2792927A1 (en) 2011-09-22
EP2548608A1 (en) 2013-01-23
CN105107083A (zh) 2015-12-02
AU2011228020A1 (en) 2012-09-27
CN105107083B (zh) 2018-04-24
ES2663095T3 (es) 2018-04-11
US9539418B2 (en) 2017-01-10
CN102811763A (zh) 2012-12-05
WO2011115272A1 (ja) 2011-09-22
EP2548608B1 (en) 2018-01-31
CN102811763B (zh) 2015-11-25
CO6620002A2 (es) 2013-02-15
MX2012010681A (es) 2012-10-09

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