BR0318631A - os agonistas receptores peptìdeo-1 similares ao glucagon, a preparação e o uso do mesmo - Google Patents

os agonistas receptores peptìdeo-1 similares ao glucagon, a preparação e o uso do mesmo

Info

Publication number
BR0318631A
BR0318631A BRPI0318631-8A BR0318631A BR0318631A BR 0318631 A BR0318631 A BR 0318631A BR 0318631 A BR0318631 A BR 0318631A BR 0318631 A BR0318631 A BR 0318631A
Authority
BR
Brazil
Prior art keywords
glucagon
peptide
preparation
receptor agonists
agonists
Prior art date
Application number
BRPI0318631-8A
Other languages
English (en)
Inventor
Fajun Nan
Mingwei Wang
Wenlong Wang
Caihong Zhou
Original Assignee
Shanghai Inst Materia Medica
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Inst Materia Medica filed Critical Shanghai Inst Materia Medica
Publication of BR0318631A publication Critical patent/BR0318631A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)

Abstract

"OS AGONISTAS RECEPTORES PEPTìDEO-1 SIMILARES AO GLUCAGON, A PREPARAçãO E O USO DO MESMO". A presente invenção apresenta agonistas receptores peptídeo-1 similares ao glucagon. é indicado que os agonistas tenham uma boa capacidade de ligação com o receptor peptídeo-1 similar ao glucagon através de testes farmacológicos. A presente invenção também apresenta a preparação dos agonistas.
BRPI0318631-8A 2003-12-12 2003-12-25 os agonistas receptores peptìdeo-1 similares ao glucagon, a preparação e o uso do mesmo BR0318631A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CNB2003101093310A CN100453533C (zh) 2003-12-12 2003-12-12 一类胰高血糖样肽－1受体激动剂及其制备方法和用途
PCT/CN2003/001115 WO2005056537A1 (fr) 2003-12-12 2003-12-25 Agonistes du recepteur peptidique 1 de type glucagon, leur preparation et leur utilisation

Publications (1)

Publication Number Publication Date
BR0318631A true BR0318631A (pt) 2006-10-31

Family

ID=34661371

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0318631-8A BR0318631A (pt) 2003-12-12 2003-12-25 os agonistas receptores peptìdeo-1 similares ao glucagon, a preparação e o uso do mesmo

Country Status (13)

Country Link
US (1) US7838682B2 (pt)
EP (1) EP1695968A4 (pt)
JP (1) JP4527665B2 (pt)
KR (1) KR100764863B1 (pt)
CN (1) CN100453533C (pt)
AU (1) AU2003296205B2 (pt)
BR (1) BR0318631A (pt)
CA (1) CA2549355A1 (pt)
IL (1) IL176223A0 (pt)
RU (1) RU2342368C2 (pt)
UA (1) UA87122C2 (pt)
WO (1) WO2005056537A1 (pt)
ZA (1) ZA200605721B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1884278A (zh) 2005-06-24 2006-12-27 中国科学院上海药物研究所 一类胰高血糖样肽－1受体调节剂、制备方法和用途
CN1896069B (zh) * 2005-07-15 2011-10-05 中国科学院上海药物研究所 一类取代噻唑-4酮化合物、制备方法和用途
CN101195585A (zh) * 2006-12-05 2008-06-11 中国科学院上海药物研究所 一类具有取代环己烷结构的化合物、及其制备方法和医学用途
CN101195612B (zh) * 2006-12-05 2012-08-08 中国科学院上海药物研究所 一类具有取代环丁烷结构的化合物、及其制备方法和医学用途
CN101195584A (zh) * 2006-12-05 2008-06-11 中国科学院上海药物研究所 一类具有取代环丙烷结构的化合物、制备方法及其医学用途
CN101195586A (zh) * 2006-12-05 2008-06-11 中国科学院上海药物研究所 一类具有取代环戊烷结构的化合物、制备方法及其医学用途
CN101195613B (zh) * 2006-12-05 2012-08-08 中国科学院上海药物研究所 一类具有取代四元环结构的化合物及其医学用途
CN101274927B (zh) * 2007-03-29 2011-04-27 中国科学院上海药物研究所 一类四元环状化合物的光化学反应制备方法及其用途
WO2011048614A2 (en) 2009-10-22 2011-04-28 Cadila Healthcare Limited Short chain peptidomimetics based orally active glp-1 agonist and glucagon receptor antagonist
US9050347B2 (en) 2011-01-25 2015-06-09 Viviabiotech, S.L. 1,2,4-oxadiazole derivatives as drugs modulating the GLP-1 peptide receptor
US9409006B2 (en) 2011-04-10 2016-08-09 David Hirshberg Fat removal device and obesity treatment
WO2020204602A1 (ko) * 2019-04-02 2020-10-08 연세대학교 산학협력단 신규 화합물 및 이를 유효성분으로 포함하는 호흡기 질환의 예방 또는 치료용 조성물

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5811950B2 (ja) * 1976-12-25 1983-03-05 味の素株式会社 ２，４−置換−５−オキサゾロンの製法
US4912221A (en) * 1988-10-27 1990-03-27 Occidental Chemical Corporation Chiral 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid and precursors and preparation thereof
JPH0350532A (ja) * 1989-07-19 1991-03-05 Ajinomoto Co Inc 有機非線形光学材料
JPH09244229A (ja) * 1996-03-07 1997-09-19 Toshiba Corp 感光性組成物及びそれを用いたパターン形成方法
JP3050532B2 (ja) * 1997-04-02 2000-06-12 山進工業株式会社 ロール
JP3092583B2 (ja) * 1998-03-23 2000-09-25 日本電気株式会社 有機エレクトロルミネッセンス素子材料およびそれを使用した有機エレクトロルミネッセンス素子
AR037714A1 (es) * 2001-12-06 2004-12-01 Maxia Pharmaceuticals Inc Derivados de tiazolidinona y oxazolidinona 2-sustituidos para la inhibicion de fosfatasas y el tratamiento de cancer

Also Published As

Publication number Publication date
CN1626521A (zh) 2005-06-15
US7838682B2 (en) 2010-11-23
ZA200605721B (en) 2007-04-25
KR20060097065A (ko) 2006-09-13
EP1695968A4 (en) 2007-08-22
RU2342368C2 (ru) 2008-12-27
AU2003296205A1 (en) 2005-06-29
US20070043093A1 (en) 2007-02-22
IL176223A0 (en) 2006-10-05
KR100764863B1 (ko) 2007-10-09
AU2003296205B2 (en) 2008-09-25
UA87122C2 (ru) 2009-06-25
JP2007523828A (ja) 2007-08-23
CN100453533C (zh) 2009-01-21
RU2006124796A (ru) 2008-01-27
JP4527665B2 (ja) 2010-08-18
CA2549355A1 (en) 2005-06-23
WO2005056537A1 (fr) 2005-06-23
EP1695968A1 (en) 2006-08-30

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: PARA INT.CL: C07D 263/42, C07D 263/46, C07D 277/34, C07D 277/36, C07D 233/70, C07D 233/84, A61K 31/4164, A61K 31/421, A61K 31/426, A61P 3/04, A61P 3/10

Ipc: C07D 263/42 (2011.01), C07D 263/46 (2011.01), C07D

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2144 DE 07/02/2012.