CY1111486T1 - Μιμητικα αντισωματα (mimetibodies) δεσμευμενα με υποδοχεα μελανοκορτινης, συνθεσεις, μεθοδοι και χρησεις - Google Patents

Μιμητικα αντισωματα (mimetibodies) δεσμευμενα με υποδοχεα μελανοκορτινης, συνθεσεις, μεθοδοι και χρησεις

Info

Publication number
CY1111486T1
CY1111486T1 CY20111100502T CY111100502T CY1111486T1 CY 1111486 T1 CY1111486 T1 CY 1111486T1 CY 20111100502 T CY20111100502 T CY 20111100502T CY 111100502 T CY111100502 T CY 111100502T CY 1111486 T1 CY1111486 T1 CY 1111486T1
Authority
CY
Cyprus
Prior art keywords
mimetibodies
methods
binded
compositions
melanocortin receptors
Prior art date
Application number
CY20111100502T
Other languages
English (en)
Inventor
Mark Cunningham
Vedrana Stojanovic-Susulic
Neil Karyn O'
Chichi Huang
Jeffrey Luo
Original Assignee
Centocor Ortho Biotech, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centocor Ortho Biotech, Inc. filed Critical Centocor Ortho Biotech, Inc.
Publication of CY1111486T1 publication Critical patent/CY1111486T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/68—Melanocyte-stimulating hormone [MSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1796—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH] (Somatotropin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Abstract

Αποκαλύπτονται πολυπεπτίδια μιμητικών αντισωμάτων δεσμευόμενα με υποδοχέα μελανοκορτίνης. Αποκαλύπτονται επίσης πολυνουκλεοτίδια που κωδικοποιούν αυτά τα πολυπεπτίδια, κύτταρα που περιλαμβάνουν αυτά τα πολυνουκλεοτίδια ή που εκφράζουν τα μιμητικά αντισώματα, και μέθοδοι κατασκευής και χρήσης των προαναφερόμενων.
CY20111100502T 2004-10-25 2011-05-23 Μιμητικα αντισωματα (mimetibodies) δεσμευμενα με υποδοχεα μελανοκορτινης, συνθεσεις, μεθοδοι και χρησεις CY1111486T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62196004P 2004-10-25 2004-10-25
EP05819741A EP1812046B1 (en) 2004-10-25 2005-10-25 Melanocortin receptor binding mimetibodies, compositions, methods and uses

Publications (1)

Publication Number Publication Date
CY1111486T1 true CY1111486T1 (el) 2015-08-05

Family

ID=36228385

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20111100502T CY1111486T1 (el) 2004-10-25 2011-05-23 Μιμητικα αντισωματα (mimetibodies) δεσμευμενα με υποδοχεα μελανοκορτινης, συνθεσεις, μεθοδοι και χρησεις

Country Status (29)

Country Link
US (1) US20060105951A1 (el)
EP (1) EP1812046B1 (el)
JP (1) JP2008517605A (el)
KR (1) KR101255140B1 (el)
CN (1) CN101437540B (el)
AT (1) ATE501731T1 (el)
AU (1) AU2005299440B2 (el)
BR (1) BRPI0518411A2 (el)
CA (1) CA2585287A1 (el)
CY (1) CY1111486T1 (el)
DE (1) DE602005026970D1 (el)
DK (1) DK1812046T3 (el)
EA (1) EA200700944A1 (el)
EC (1) ECSP077416A (el)
ES (1) ES2363023T3 (el)
HK (1) HK1106445A1 (el)
HR (1) HRP20110405T1 (el)
IL (1) IL182683A0 (el)
MA (1) MA28943B1 (el)
ME (1) ME01234B (el)
MX (1) MX2007004974A (el)
NO (1) NO20072499L (el)
PL (1) PL1812046T3 (el)
PT (1) PT1812046E (el)
RS (1) RS51789B (el)
SI (1) SI1812046T1 (el)
TN (1) TNSN07157A1 (el)
WO (1) WO2006047535A2 (el)
ZA (1) ZA200704260B (el)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7910101B2 (en) * 2004-10-25 2011-03-22 Centocor, Inc. Melanocortin receptor binding mimetibodies, compositions, methods and uses
US7790671B2 (en) * 2005-10-07 2010-09-07 Codman & Shurtleff, Inc. Implantable pump for protein delivery for obesity control by drug infusion into the brain
NZ590254A (en) * 2008-06-09 2012-07-27 Palatin Technologies Inc Melanocortin receptor-specific cyclic peptides for treatment of sexual dysfunction
WO2009151383A1 (en) * 2008-06-09 2009-12-17 Palatin Technologies, Inc. Melanocortin receptor-specific peptides for the treatment of obesity and other diseases associated with melanocortin receptor function
US8614185B2 (en) * 2009-05-04 2013-12-24 Centocor Ortho Biotech Inc. Fusion proteins of alpha-MSH derivatives and Fc
UY32690A (es) 2009-06-08 2011-01-31 Astrazeneca Ab Péptidos específicos para receptores de melanocortina
WO2010144341A2 (en) 2009-06-08 2010-12-16 Palatin Technologies, Inc. Lactam-bridged melanocortin receptor-specific peptides
CN102458436B (zh) 2009-06-08 2015-06-03 帕拉丁科技公司 黑皮质素受体特异性肽
EP2504351A4 (en) 2009-11-23 2013-10-30 Palatin Technologies Inc MELANOCORTIN-1 RECEPTOR-SPECIFIC LINEAR PEPTIDE
BR112012011787B1 (pt) 2009-11-23 2022-03-03 Palatin Technologies, Inc Peptídeo cíclico e composição farmacêutica
JP2020141710A (ja) * 2011-07-06 2020-09-10 ゲンマブ エー／エス 抗体重鎖のｃ末端の修飾による補体依存性細胞傷害の調節
CN113272330A (zh) * 2019-03-02 2021-08-17 上海一宸医药科技有限公司 一种双特异抗体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1137340A4 (en) * 1998-12-09 2005-12-21 Eleanor Roosevelt Inst COMPOSITION AND METHOD FOR REGULATING BODY WEIGHT AND ASSOCIATED CONDITIONS
AU7593001A (en) * 2000-07-14 2002-01-30 Zycos Inc Alpha-msh related compounds and methods of use
EP1575499A2 (en) * 2002-06-28 2005-09-21 Centocor, Inc. Mammalian epo mimetic ch1 deleted mimetibodies, compositions, methods and uses
EP1545608A4 (en) * 2002-06-28 2006-09-13 Centocor Inc CH1-DELETED MAMMED MUICETIC BODIES, COMPOSITIONS, METHODS AND APPLICATIONS
JP2008537873A (ja) * 2004-03-31 2008-10-02 セントカー・インコーポレーテツド ヒトｇｌｐ−１ミメティボディ、組成物、方法および用途

Also Published As

Publication number Publication date
RS51789B (en) 2011-12-31
CN101437540A (zh) 2009-05-20
CN101437540B (zh) 2012-12-19
ZA200704260B (en) 2009-03-25
DK1812046T3 (da) 2011-06-06
DE602005026970D1 (de) 2011-04-28
PT1812046E (pt) 2011-06-28
MA28943B1 (fr) 2007-10-01
JP2008517605A (ja) 2008-05-29
SI1812046T1 (sl) 2011-06-30
WO2006047535A2 (en) 2006-05-04
WO2006047535A3 (en) 2008-09-04
AU2005299440B2 (en) 2011-12-15
ATE501731T1 (de) 2011-04-15
KR101255140B1 (ko) 2013-04-22
CA2585287A1 (en) 2006-05-04
AU2005299440A1 (en) 2006-05-04
EA200700944A1 (ru) 2008-04-28
KR20070085416A (ko) 2007-08-27
HK1106445A1 (en) 2008-03-14
IL182683A0 (en) 2007-09-20
ECSP077416A (es) 2007-05-30
EP1812046B1 (en) 2011-03-16
ES2363023T3 (es) 2011-07-19
HRP20110405T1 (hr) 2011-06-30
BRPI0518411A2 (pt) 2008-11-18
PL1812046T3 (pl) 2011-08-31
MX2007004974A (es) 2007-10-17
US20060105951A1 (en) 2006-05-18
EP1812046A2 (en) 2007-08-01
NO20072499L (no) 2007-07-16
EP1812046A4 (en) 2009-11-11
ME01234B (me) 2013-06-20
TNSN07157A1 (en) 2008-11-21

Similar Documents

Publication Publication Date Title
CY1111486T1 (el) Μιμητικα αντισωματα (mimetibodies) δεσμευμενα με υποδοχεα μελανοκορτινης, συνθεσεις, μεθοδοι και χρησεις
WO2007041635A3 (en) Fc variants with optimized fc receptor binding properties
ATE465176T1 (de) Il-7-varianten mit reduzierter immunogenität
ATE493081T1 (de) Faserverstärktes verbundmaterial
WO2004078938A3 (en) Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
TW200631594A (en) Toll like receptor 3 antagonists, methods and uses
DE112005001162B8 (de) Brennstoffzellensystem
DE602005014408D1 (de) Brennstoffzellensystem
DE602005020227D1 (de) Brennstoffzellensystem
BRPI0506777A (pt) antagonistas do receptor muscarìnico da acetilcolina
ATE458740T1 (de) 1,4,5,6,7,8-hexahydro-1,2,5-triaza-azulen- derivate als orexinrezeptor-antagonisten
TW200745159A (en) IL-6 binding proteins
MX2007011411A (es) Interaccion rage/diaphanous y composiciones relacionadas y metodos.
DE602005017547D1 (de) Brennstoffzellensystem
TW200711846A (en) Composite materials and methods of making the same
DE602005013216D1 (de) Mercaptoimidazole als ccr2-rezeptorantagonisten
DE602006010187D1 (de) Einzelsequenzhybridisierungssonden
WO2007056760A3 (en) Hcv-reactive t cell receptors
FI20045335A0 (fi) Polttokennojärjestely
ES1057969Y (es) Pieza constructiva tipo sandwich.
ES1057970Y (es) Pieza constructiva tipo sandwich.
TR200401831A2 (tr) Bims-Kiremit ve özel parçaları.
GB0419677D0 (en) Novel polypeptides, antibodies thereto and uses thereof
TH97791A (th) เอริโธรพอยเอทินรีเซปเตอร์อะโกนิสต์
ITTR20050009U1 (it) Quaderno, quadernone, blocco o album con copertina personalizzata.