DE602005026970D1 - Melanocortin-rezeptor-bindende mimetibodies, zusammensetzungen, verfahren und verwendungen - Google Patents

Melanocortin-rezeptor-bindende mimetibodies, zusammensetzungen, verfahren und verwendungen

Info

Publication number
DE602005026970D1
DE602005026970D1 DE602005026970T DE602005026970T DE602005026970D1 DE 602005026970 D1 DE602005026970 D1 DE 602005026970D1 DE 602005026970 T DE602005026970 T DE 602005026970T DE 602005026970 T DE602005026970 T DE 602005026970T DE 602005026970 D1 DE602005026970 D1 DE 602005026970D1
Authority
DE
Germany
Prior art keywords
receptor binding
compositions
processes
melanocortin receptor
mimetibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005026970T
Other languages
English (en)
Inventor
Mark Cunningham
Vedrana Stojanovic-Susulic
Karyn O'neil
Chichi Huang
Jeffrey Luo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Biotech Inc
Original Assignee
Centocor Ortho Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centocor Ortho Biotech Inc filed Critical Centocor Ortho Biotech Inc
Publication of DE602005026970D1 publication Critical patent/DE602005026970D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/68—Melanocyte-stimulating hormone [MSH]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1796—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH] (Somatotropin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE602005026970T 2004-10-25 2005-10-25 Melanocortin-rezeptor-bindende mimetibodies, zusammensetzungen, verfahren und verwendungen Active DE602005026970D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62196004P 2004-10-25 2004-10-25
PCT/US2005/038431 WO2006047535A2 (en) 2004-10-25 2005-10-25 Melanocortin receptor binding mimetibodies, compositions, methods and uses

Publications (1)

Publication Number Publication Date
DE602005026970D1 true DE602005026970D1 (de) 2011-04-28

Family

ID=36228385

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005026970T Active DE602005026970D1 (de) 2004-10-25 2005-10-25 Melanocortin-rezeptor-bindende mimetibodies, zusammensetzungen, verfahren und verwendungen

Country Status (29)

Country Link
US (1) US20060105951A1 (de)
EP (1) EP1812046B1 (de)
JP (1) JP2008517605A (de)
KR (1) KR101255140B1 (de)
CN (1) CN101437540B (de)
AT (1) ATE501731T1 (de)
AU (1) AU2005299440B2 (de)
BR (1) BRPI0518411A2 (de)
CA (1) CA2585287A1 (de)
CY (1) CY1111486T1 (de)
DE (1) DE602005026970D1 (de)
DK (1) DK1812046T3 (de)
EA (1) EA200700944A1 (de)
EC (1) ECSP077416A (de)
ES (1) ES2363023T3 (de)
HK (1) HK1106445A1 (de)
HR (1) HRP20110405T1 (de)
IL (1) IL182683A0 (de)
MA (1) MA28943B1 (de)
ME (1) ME01234B (de)
MX (1) MX2007004974A (de)
NO (1) NO20072499L (de)
PL (1) PL1812046T3 (de)
PT (1) PT1812046E (de)
RS (1) RS51789B (de)
SI (1) SI1812046T1 (de)
TN (1) TNSN07157A1 (de)
WO (1) WO2006047535A2 (de)
ZA (1) ZA200704260B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7910101B2 (en) * 2004-10-25 2011-03-22 Centocor, Inc. Melanocortin receptor binding mimetibodies, compositions, methods and uses
US7790671B2 (en) * 2005-10-07 2010-09-07 Codman & Shurtleff, Inc. Implantable pump for protein delivery for obesity control by drug infusion into the brain
NZ590254A (en) * 2008-06-09 2012-07-27 Palatin Technologies Inc Melanocortin receptor-specific cyclic peptides for treatment of sexual dysfunction
WO2009151383A1 (en) * 2008-06-09 2009-12-17 Palatin Technologies, Inc. Melanocortin receptor-specific peptides for the treatment of obesity and other diseases associated with melanocortin receptor function
US8614185B2 (en) * 2009-05-04 2013-12-24 Centocor Ortho Biotech Inc. Fusion proteins of alpha-MSH derivatives and Fc
UY32690A (es) 2009-06-08 2011-01-31 Astrazeneca Ab Péptidos específicos para receptores de melanocortina
WO2010144341A2 (en) 2009-06-08 2010-12-16 Palatin Technologies, Inc. Lactam-bridged melanocortin receptor-specific peptides
CN102458436B (zh) 2009-06-08 2015-06-03 帕拉丁科技公司 黑皮质素受体特异性肽
EP2504351A4 (de) 2009-11-23 2013-10-30 Palatin Technologies Inc Melanocortin-1-rezeptor-spezifische lineare peptide
BR112012011787B1 (pt) 2009-11-23 2022-03-03 Palatin Technologies, Inc Peptídeo cíclico e composição farmacêutica
JP2020141710A (ja) * 2011-07-06 2020-09-10 ゲンマブ エー／エス 抗体重鎖のｃ末端の修飾による補体依存性細胞傷害の調節
CN113272330A (zh) * 2019-03-02 2021-08-17 上海一宸医药科技有限公司 一种双特异抗体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1137340A4 (de) * 1998-12-09 2005-12-21 Eleanor Roosevelt Inst Zusammensetzung und verfahren zur regulation des körpergewichtes und damit zusammenhängender zustände
AU7593001A (en) * 2000-07-14 2002-01-30 Zycos Inc Alpha-msh related compounds and methods of use
EP1575499A2 (de) * 2002-06-28 2005-09-21 Centocor, Inc. Säugetier-mimetikkörper mit epo mimetikum ch1 deletion, zusammensetzungen, verfahren und verwendungen
EP1545608A4 (de) * 2002-06-28 2006-09-13 Centocor Inc Ch1-deletierte säugetier-mimetikörper, zusammensetzungen, verfahren und anwendungen
JP2008537873A (ja) * 2004-03-31 2008-10-02 セントカー・インコーポレーテツド ヒトｇｌｐ−１ミメティボディ、組成物、方法および用途

Also Published As

Publication number Publication date
RS51789B (en) 2011-12-31
CN101437540A (zh) 2009-05-20
CN101437540B (zh) 2012-12-19
ZA200704260B (en) 2009-03-25
DK1812046T3 (da) 2011-06-06
PT1812046E (pt) 2011-06-28
MA28943B1 (fr) 2007-10-01
JP2008517605A (ja) 2008-05-29
SI1812046T1 (sl) 2011-06-30
WO2006047535A2 (en) 2006-05-04
WO2006047535A3 (en) 2008-09-04
AU2005299440B2 (en) 2011-12-15
ATE501731T1 (de) 2011-04-15
KR101255140B1 (ko) 2013-04-22
CA2585287A1 (en) 2006-05-04
AU2005299440A1 (en) 2006-05-04
EA200700944A1 (ru) 2008-04-28
KR20070085416A (ko) 2007-08-27
HK1106445A1 (en) 2008-03-14
IL182683A0 (en) 2007-09-20
CY1111486T1 (el) 2015-08-05
ECSP077416A (es) 2007-05-30
EP1812046B1 (de) 2011-03-16
ES2363023T3 (es) 2011-07-19
HRP20110405T1 (hr) 2011-06-30
BRPI0518411A2 (pt) 2008-11-18
PL1812046T3 (pl) 2011-08-31
MX2007004974A (es) 2007-10-17
US20060105951A1 (en) 2006-05-18
EP1812046A2 (de) 2007-08-01
NO20072499L (no) 2007-07-16
EP1812046A4 (de) 2009-11-11
ME01234B (me) 2013-06-20
TNSN07157A1 (en) 2008-11-21

Similar Documents

Publication Publication Date Title
DE602005026970D1 (de) Melanocortin-rezeptor-bindende mimetibodies, zusammensetzungen, verfahren und verwendungen
NL301145I2 (nl) Tirbanibulin
HRP20190220T1 (hr) Anti-il-23 protutijela, pripravci, postupci i upotrebe
EA200702278A1 (ru) Антитела, специфичные в отношении tgf-бета 1
WO2007041635A3 (en) Fc variants with optimized fc receptor binding properties
DK1864132T3 (da) Fra amnion stammende cellesammensætninger, fremgangsmåder til fremstilling deraf og anvendelser deraf
TW200611910A (en) Interferon-alpha polypeptides and conjugates
WO2007014169A3 (en) Anti-cd26 antibodies and methods of use thereof
WO2006017538A3 (en) Hk1-binding proteins
WO2006055689A3 (en) Protein scaffolds and uses thereof
GB0700909D0 (en) Novel antigen-binding polypeptides and their uses
WO2006105338A3 (en) Fc VARIANTS WITH OPTIMIZED PROPERTIES
WO2006083276A3 (en) Interferon-alpha polypeptides and conjugates
EP1799700A4 (de) Srage-mimetikörper, -zusammensetzungen, -verfahren und -verwendungen
MX2008001652A (es) Copolimeros de poliamonio-polisiloxano.
NO20055686L (no) Sammensetning, fremgangsmate til fremstilling derav, og anvendelse derav.
DK1919514T3 (da) Polynucleotider kodende for isoprenoid-modificerende enzymer og fremgangsmåder til anvendelse deraf
TW200745159A (en) IL-6 binding proteins
WO2007044083A3 (en) Evolved interferon-alpha polypeptides
MX2007011411A (es) Interaccion rage/diaphanous y composiciones relacionadas y metodos.
TW200711846A (en) Composite materials and methods of making the same
WO2005082088A3 (en) Functional genomics and gene trapping in haploid or hypodiploid cells
ATE486895T1 (de) Pfropfcopolymer enthaltende abweisende zusammensetzung, pfropfcopolymer und herstellungsverfahren dafür