ECSP077416A - Mimeticuerpos que se unen al receptor de melanocortina, composiciones, metodos y usos - Google Patents

Mimeticuerpos que se unen al receptor de melanocortina, composiciones, metodos y usos

Info

Publication number
ECSP077416A
ECSP077416A EC2007007416A ECSP077416A ECSP077416A EC SP077416 A ECSP077416 A EC SP077416A EC 2007007416 A EC2007007416 A EC 2007007416A EC SP077416 A ECSP077416 A EC SP077416A EC SP077416 A ECSP077416 A EC SP077416A
Authority
EC
Ecuador
Prior art keywords
methods
mimeticbodies
join
compositions
melanocortine
Prior art date
Application number
EC2007007416A
Other languages
English (en)
Inventor
Chichi Huang
Mark Cunningham
Vedrana Stojanovic-Susulic
Karyn O'neil
Jeffrey Luo
Original Assignee
Centocor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centocor Inc filed Critical Centocor Inc
Publication of ECSP077416A publication Critical patent/ECSP077416A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/68—Melanocyte-stimulating hormone [MSH]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1796—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se expone un polipéptido de mimeticuerpo de unión al receptor de melanocortina; se exponen también polinucleótidos que codifican estos polipéptidos, células que comprenden estos polinucleótidos o que expresan los mimeticuerpos, y métodos de hacer y usar los anteriores.
EC2007007416A 2004-10-25 2007-04-25 Mimeticuerpos que se unen al receptor de melanocortina, composiciones, metodos y usos ECSP077416A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62196004P 2004-10-25 2004-10-25

Publications (1)

Publication Number Publication Date
ECSP077416A true ECSP077416A (es) 2007-05-30

Family

ID=36228385

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2007007416A ECSP077416A (es) 2004-10-25 2007-04-25 Mimeticuerpos que se unen al receptor de melanocortina, composiciones, metodos y usos

Country Status (29)

Country Link
US (1) US20060105951A1 (es)
EP (1) EP1812046B1 (es)
JP (1) JP2008517605A (es)
KR (1) KR101255140B1 (es)
CN (1) CN101437540B (es)
AT (1) ATE501731T1 (es)
AU (1) AU2005299440B2 (es)
BR (1) BRPI0518411A2 (es)
CA (1) CA2585287A1 (es)
CY (1) CY1111486T1 (es)
DE (1) DE602005026970D1 (es)
DK (1) DK1812046T3 (es)
EA (1) EA200700944A1 (es)
EC (1) ECSP077416A (es)
ES (1) ES2363023T3 (es)
HK (1) HK1106445A1 (es)
HR (1) HRP20110405T1 (es)
IL (1) IL182683A0 (es)
MA (1) MA28943B1 (es)
ME (1) ME01234B (es)
MX (1) MX2007004974A (es)
NO (1) NO20072499L (es)
PL (1) PL1812046T3 (es)
PT (1) PT1812046E (es)
RS (1) RS51789B (es)
SI (1) SI1812046T1 (es)
TN (1) TNSN07157A1 (es)
WO (1) WO2006047535A2 (es)
ZA (1) ZA200704260B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7910101B2 (en) * 2004-10-25 2011-03-22 Centocor, Inc. Melanocortin receptor binding mimetibodies, compositions, methods and uses
US7790671B2 (en) * 2005-10-07 2010-09-07 Codman & Shurtleff, Inc. Implantable pump for protein delivery for obesity control by drug infusion into the brain
CN102131514B (zh) * 2008-06-09 2014-08-20 帕拉丁科技公司 用于治疗性功能障碍的黑皮质素受体特异性肽
US20090305960A1 (en) * 2008-06-09 2009-12-10 Palatin Technologies, Inc Melanocortin Receptor-Specific Peptides for Treatment of Obesity / 669
US8614185B2 (en) * 2009-05-04 2013-12-24 Centocor Ortho Biotech Inc. Fusion proteins of alpha-MSH derivatives and Fc
UY32690A (es) 2009-06-08 2011-01-31 Astrazeneca Ab Péptidos específicos para receptores de melanocortina
CN102458436B (zh) 2009-06-08 2015-06-03 帕拉丁科技公司 黑皮质素受体特异性肽
WO2010144341A2 (en) 2009-06-08 2010-12-16 Palatin Technologies, Inc. Lactam-bridged melanocortin receptor-specific peptides
MX2012005859A (es) 2009-11-23 2012-12-17 Palatin Technologies Inc Peptidos lineales especificos del receptor de melanocortina-1.
EA021897B1 (ru) 2009-11-23 2015-09-30 Палатин Текнолоджиз, Инк. Циклические пептиды, специфичные к рецептору меланокортина-1
JP2020141710A (ja) * 2011-07-06 2020-09-10 ゲンマブ エー／エス 抗体重鎖のｃ末端の修飾による補体依存性細胞傷害の調節
WO2020177627A1 (zh) * 2019-03-02 2020-09-10 上海一宸医药科技有限公司 一种双特异抗体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA01005818A (es) * 1998-12-09 2003-07-21 Eleanor Rooseveltl Inst Composicion y metodo para la regulacion del peso del cuerpo y condiciones asociadas.
WO2002006316A2 (en) * 2000-07-14 2002-01-24 Zycos, Inc. Alpha-msh related compounds and methods of use
EP1575499A2 (en) * 2002-06-28 2005-09-21 Centocor, Inc. Mammalian epo mimetic ch1 deleted mimetibodies, compositions, methods and uses
EP1545608A4 (en) * 2002-06-28 2006-09-13 Centocor Inc CH1-DELETED MAMMED MUICETIC BODIES, COMPOSITIONS, METHODS AND APPLICATIONS
SG151315A1 (en) * 2004-03-31 2009-04-30 Centocor Inc Human glp-1 mimetibodies, compositions, methods and uses

Also Published As

Publication number Publication date
CN101437540B (zh) 2012-12-19
NO20072499L (no) 2007-07-16
WO2006047535A2 (en) 2006-05-04
EA200700944A1 (ru) 2008-04-28
MX2007004974A (es) 2007-10-17
TNSN07157A1 (en) 2008-11-21
PL1812046T3 (pl) 2011-08-31
BRPI0518411A2 (pt) 2008-11-18
WO2006047535A3 (en) 2008-09-04
KR20070085416A (ko) 2007-08-27
HK1106445A1 (en) 2008-03-14
HRP20110405T1 (hr) 2011-06-30
RS51789B (en) 2011-12-31
US20060105951A1 (en) 2006-05-18
MA28943B1 (fr) 2007-10-01
ZA200704260B (en) 2009-03-25
CN101437540A (zh) 2009-05-20
JP2008517605A (ja) 2008-05-29
AU2005299440A1 (en) 2006-05-04
KR101255140B1 (ko) 2013-04-22
SI1812046T1 (sl) 2011-06-30
ATE501731T1 (de) 2011-04-15
DE602005026970D1 (de) 2011-04-28
EP1812046A2 (en) 2007-08-01
EP1812046A4 (en) 2009-11-11
ME01234B (me) 2013-06-20
CY1111486T1 (el) 2015-08-05
EP1812046B1 (en) 2011-03-16
AU2005299440B2 (en) 2011-12-15
IL182683A0 (en) 2007-09-20
DK1812046T3 (da) 2011-06-06
ES2363023T3 (es) 2011-07-19
PT1812046E (pt) 2011-06-28
CA2585287A1 (en) 2006-05-04

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