UA87122C2 - Агонисты рецепторов глюкагонподобного пептида-1, их применение и способ получения - Google Patents

Агонисты рецепторов глюкагонподобного пептида-1, их применение и способ получения

Info

Publication number
UA87122C2
UA87122C2 UAA200607009A UAA200607009A UA87122C2 UA 87122 C2 UA87122 C2 UA 87122C2 UA A200607009 A UAA200607009 A UA A200607009A UA A200607009 A UAA200607009 A UA A200607009A UA 87122 C2 UA87122 C2 UA 87122C2
Authority
UA
Ukraine
Prior art keywords
glucagon
peptide
preparation
same
receptor agonists
Prior art date
Application number
UAA200607009A
Other languages
English (en)
Ukrainian (uk)
Inventor
Файун Нан
Мингвей Вонг
Венлонг Вонг
Кайхонг Зхоу
Original Assignee
Шангхаи Инститьют Оф Матирия Медика, Чайниз Акедеми Оф Сайнс
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Шангхаи Инститьют Оф Матирия Медика, Чайниз Акедеми Оф Сайнс filed Critical Шангхаи Инститьют Оф Матирия Медика, Чайниз Акедеми Оф Сайнс
Publication of UA87122C2 publication Critical patent/UA87122C2/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)

Abstract

Объектом данного изобретения являются агонисты рецептора глюкагоноподобного пептида-1. Изобретение иллюстрирует с помощью фармакологических тестов способность агонистов связываться с рецептором глюкагонподобного пептида-1.Объектом данного изобретения является также способ получения агонистов.
UAA200607009A 2003-12-12 2003-12-25 Агонисты рецепторов глюкагонподобного пептида-1, их применение и способ получения UA87122C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNB2003101093310A CN100453533C (zh) 2003-12-12 2003-12-12 一类胰高血糖样肽－1受体激动剂及其制备方法和用途

Publications (1)

Publication Number Publication Date
UA87122C2 true UA87122C2 (ru) 2009-06-25

Family

ID=34661371

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200607009A UA87122C2 (ru) 2003-12-12 2003-12-25 Агонисты рецепторов глюкагонподобного пептида-1, их применение и способ получения

Country Status (13)

Country Link
US (1) US7838682B2 (ru)
EP (1) EP1695968A4 (ru)
JP (1) JP4527665B2 (ru)
KR (1) KR100764863B1 (ru)
CN (1) CN100453533C (ru)
AU (1) AU2003296205B2 (ru)
BR (1) BR0318631A (ru)
CA (1) CA2549355A1 (ru)
IL (1) IL176223A0 (ru)
RU (1) RU2342368C2 (ru)
UA (1) UA87122C2 (ru)
WO (1) WO2005056537A1 (ru)
ZA (1) ZA200605721B (ru)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1884278A (zh) * 2005-06-24 2006-12-27 中国科学院上海药物研究所 一类胰高血糖样肽－1受体调节剂、制备方法和用途
CN1896069B (zh) * 2005-07-15 2011-10-05 中国科学院上海药物研究所 一类取代噻唑-4酮化合物、制备方法和用途
CN101195613B (zh) * 2006-12-05 2012-08-08 中国科学院上海药物研究所 一类具有取代四元环结构的化合物及其医学用途
CN101195584A (zh) * 2006-12-05 2008-06-11 中国科学院上海药物研究所 一类具有取代环丙烷结构的化合物、制备方法及其医学用途
CN101195586A (zh) * 2006-12-05 2008-06-11 中国科学院上海药物研究所 一类具有取代环戊烷结构的化合物、制备方法及其医学用途
CN101195585A (zh) * 2006-12-05 2008-06-11 中国科学院上海药物研究所 一类具有取代环己烷结构的化合物、及其制备方法和医学用途
CN101195612B (zh) * 2006-12-05 2012-08-08 中国科学院上海药物研究所 一类具有取代环丁烷结构的化合物、及其制备方法和医学用途
CN101274927B (zh) * 2007-03-29 2011-04-27 中国科学院上海药物研究所 一类四元环状化合物的光化学反应制备方法及其用途
US20120264685A1 (en) 2009-10-22 2012-10-18 Rajesh Bahekar Short chain peptidomimetics based orally active glp 1 agonist and glucagon receptor antagonist
EP2668951B9 (en) 2011-01-25 2017-03-15 Viviabiotech, S.L. 1,2,4-oxadiazole derivatives as drugs modulating the glp-1 peptide receptor
US9409006B2 (en) 2011-04-10 2016-08-09 David Hirshberg Fat removal device and obesity treatment
EP3949963A4 (en) * 2019-04-02 2023-01-04 Yonsei University, University-Industry Foundation(UIF). NEW COMPOUND AND COMPOSITION FOR THE PREVENTION OR TREATMENT OF RESPIRATORY DISEASES COMPRISING THIS AS AN ACTIVE PRINCIPLE

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5811950B2 (ja) * 1976-12-25 1983-03-05 味の素株式会社 ２，４−置換−５−オキサゾロンの製法
US4912221A (en) * 1988-10-27 1990-03-27 Occidental Chemical Corporation Chiral 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid and precursors and preparation thereof
JPH0350532A (ja) * 1989-07-19 1991-03-05 Ajinomoto Co Inc 有機非線形光学材料
JPH09244229A (ja) * 1996-03-07 1997-09-19 Toshiba Corp 感光性組成物及びそれを用いたパターン形成方法
JP3050532B2 (ja) * 1997-04-02 2000-06-12 山進工業株式会社 ロール
JP3092583B2 (ja) * 1998-03-23 2000-09-25 日本電気株式会社 有機エレクトロルミネッセンス素子材料およびそれを使用した有機エレクトロルミネッセンス素子
AR037714A1 (es) * 2001-12-06 2004-12-01 Maxia Pharmaceuticals Inc Derivados de tiazolidinona y oxazolidinona 2-sustituidos para la inhibicion de fosfatasas y el tratamiento de cancer

Also Published As

Publication number Publication date
JP2007523828A (ja) 2007-08-23
RU2342368C2 (ru) 2008-12-27
US20070043093A1 (en) 2007-02-22
KR20060097065A (ko) 2006-09-13
CN1626521A (zh) 2005-06-15
CA2549355A1 (en) 2005-06-23
IL176223A0 (en) 2006-10-05
AU2003296205A1 (en) 2005-06-29
KR100764863B1 (ko) 2007-10-09
US7838682B2 (en) 2010-11-23
WO2005056537A1 (fr) 2005-06-23
EP1695968A4 (en) 2007-08-22
ZA200605721B (en) 2007-04-25
BR0318631A (pt) 2006-10-31
AU2003296205B2 (en) 2008-09-25
EP1695968A1 (en) 2006-08-30
RU2006124796A (ru) 2008-01-27
JP4527665B2 (ja) 2010-08-18
CN100453533C (zh) 2009-01-21

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