BR0313131A - Processo para a purificação de preproinsulina - Google Patents

Processo para a purificação de preproinsulina

Info

Publication number
BR0313131A
BR0313131A BR0313131-9A BR0313131A BR0313131A BR 0313131 A BR0313131 A BR 0313131A BR 0313131 A BR0313131 A BR 0313131A BR 0313131 A BR0313131 A BR 0313131A
Authority
BR
Brazil
Prior art keywords
preproinsulin
purification
preproinsulins
chromatography
preparing
Prior art date
Application number
BR0313131-9A
Other languages
English (en)
Portuguese (pt)
Inventor
Horst Thurow
Hans Blumenstock
Chantalle Havenith
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of BR0313131A publication Critical patent/BR0313131A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
BR0313131-9A 2002-08-01 2003-07-18 Processo para a purificação de preproinsulina BR0313131A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10235168A DE10235168A1 (de) 2002-08-01 2002-08-01 Verfahren zur Reinigung von Preproinsulin
PCT/EP2003/007820 WO2004013176A1 (de) 2002-08-01 2003-07-18 Verfahren zur reinigung von preproinsulin

Publications (1)

Publication Number Publication Date
BR0313131A true BR0313131A (pt) 2005-07-05

Family

ID=30128614

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0313131-9A BR0313131A (pt) 2002-08-01 2003-07-18 Processo para a purificação de preproinsulina

Country Status (16)

Country Link
US (2) US20050080000A1 (https=)
EP (1) EP1527097B1 (https=)
JP (1) JP4519646B2 (https=)
AT (1) ATE384742T1 (https=)
AU (1) AU2003254375B2 (https=)
BR (1) BR0313131A (https=)
CA (1) CA2493539C (https=)
CY (1) CY1108046T1 (https=)
DE (2) DE10235168A1 (https=)
DK (1) DK1527097T3 (https=)
ES (1) ES2297223T3 (https=)
IL (1) IL166438A (https=)
MX (1) MXPA05001042A (https=)
PT (1) PT1527097E (https=)
SI (1) SI1527097T1 (https=)
WO (1) WO2004013176A1 (https=)

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TR201809460T4 (tr) 2009-11-13 2018-07-23 Sanofi Aventis Deutschland Bir GLP- 1-agonisti, bir insülin ve metiyonin içeren farmasötik bileşim.
AU2011202239C1 (en) 2010-05-19 2017-03-16 Sanofi Long-acting formulations of insulins
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DE102011003944A1 (de) 2011-02-10 2012-08-16 Oxprotect Gmbh Detektion und Entfernung von missgefalteten Proteinen/Peptiden
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US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
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MX2014004983A (es) 2011-10-24 2014-09-22 Mannkid Corp Metodos y composiciones para tratar dolor.
KR102264177B1 (ko) 2012-07-12 2021-06-11 맨카인드 코포레이션 건조 분말 약물 전달 시스템 및 방법
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EP2931301B2 (en) 2012-12-17 2021-09-15 Merck Sharp & Dohme Corp. Process for purifying insulin and analogues thereof
EP3587404B1 (en) 2013-03-15 2022-07-13 MannKind Corporation Microcrystalline diketopiperazine compositions, methods for preparation and use thereof
EP2983697B1 (en) 2013-04-03 2018-10-31 Sanofi Treatment of diabetes mellitus by long acting formulations of insulins
MX375448B (es) 2013-07-18 2025-03-06 Mannkind Corp Composiciones farmacéuticas en polvo seco estables al calor y métodos.
EP3030294B1 (en) 2013-08-05 2020-10-07 MannKind Corporation Insufflation apparatus
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
CN106794156B (zh) * 2014-07-08 2021-03-09 美药星制药股份有限公司 微粒化胰岛素、微粒化胰岛素类似物及其制备方法
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PE20171622A1 (es) 2014-12-12 2017-11-02 Sanofi Aventis Deutschland Formulacion de relacion fija de insulina glargina/lixisenatida
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Also Published As

Publication number Publication date
AU2003254375B2 (en) 2009-01-08
JP2006513978A (ja) 2006-04-27
US20060183666A1 (en) 2006-08-17
US20050080000A1 (en) 2005-04-14
SI1527097T1 (sl) 2008-04-30
AU2003254375A1 (en) 2004-02-23
ATE384742T1 (de) 2008-02-15
JP4519646B2 (ja) 2010-08-04
DE50309087D1 (https=) 2008-03-13
PT1527097E (pt) 2008-02-25
ES2297223T3 (es) 2008-05-01
DK1527097T3 (da) 2008-05-26
EP1527097A1 (de) 2005-05-04
CY1108046T1 (el) 2013-09-04
WO2004013176A1 (de) 2004-02-12
US7803763B2 (en) 2010-09-28
IL166438A (en) 2010-11-30
DE10235168A1 (de) 2004-02-12
MXPA05001042A (es) 2005-04-08
CA2493539C (en) 2012-01-31
CA2493539A1 (en) 2004-02-12
EP1527097B1 (de) 2008-01-23
IL166438A0 (en) 2006-01-15

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Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved

Owner name: SANOFI-AVENTIS DEUTSCHLAND GMBH (DE)

Free format text: ALTERADO DE: AVENTIS PHARMA DEUTSCHLAND GMBH

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 13A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2385 DE 20-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]