BR0312456A - Anticorpo alterado ou fragmento funcional do mesmo, polinucleotìdeo, sequência de polinucleotìdeo, composição farmacêutica, métodos de tratamento ou profilaxia de derrame e outras doenças/distúrbios neurológicos em um ser humano, de inibição da neurodegeneração e/ou promoção da recuperação funcional e de promoção do desenvolvimento axonial, e, uso de um anticorpo anti-mag - Google Patents
Anticorpo alterado ou fragmento funcional do mesmo, polinucleotìdeo, sequência de polinucleotìdeo, composição farmacêutica, métodos de tratamento ou profilaxia de derrame e outras doenças/distúrbios neurológicos em um ser humano, de inibição da neurodegeneração e/ou promoção da recuperação funcional e de promoção do desenvolvimento axonial, e, uso de um anticorpo anti-magInfo
- Publication number
- BR0312456A BR0312456A BR0312456-8A BR0312456A BR0312456A BR 0312456 A BR0312456 A BR 0312456A BR 0312456 A BR0312456 A BR 0312456A BR 0312456 A BR0312456 A BR 0312456A
- Authority
- BR
- Brazil
- Prior art keywords
- promoting
- antibody
- polynucleotide
- treatment
- disorders
- Prior art date
Links
- 208000012902 Nervous system disease Diseases 0.000 title abstract 4
- 208000025966 Neurological disease Diseases 0.000 title abstract 4
- 102000040430 polynucleotide Human genes 0.000 title abstract 4
- 108091033319 polynucleotide Proteins 0.000 title abstract 4
- 239000002157 polynucleotide Substances 0.000 title abstract 4
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 238000011282 treatment Methods 0.000 title abstract 3
- 230000002401 inhibitory effect Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 230000004770 neurodegeneration Effects 0.000 title abstract 2
- 238000011321 prophylaxis Methods 0.000 title abstract 2
- 238000011084 recovery Methods 0.000 title abstract 2
- 230000001737 promoting effect Effects 0.000 title 2
- 230000003376 axonal effect Effects 0.000 title 1
- 239000012634 fragment Substances 0.000 title 1
- 102000017099 Myelin-Associated Glycoprotein Human genes 0.000 abstract 2
- 108010013731 Myelin-Associated Glycoprotein Proteins 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Psychology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Psychiatry (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Hospice & Palliative Care (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0218230A GB0218230D0 (en) | 2002-08-06 | 2002-08-06 | Antibodies |
| GB0218229A GB0218229D0 (en) | 2002-08-06 | 2002-08-06 | Antibodies |
| GB0218232A GB0218232D0 (en) | 2002-08-06 | 2002-08-06 | Antibodies |
| GB0218234A GB0218234D0 (en) | 2002-08-06 | 2002-08-06 | Antibodies |
| PCT/EP2003/008749 WO2004014953A2 (en) | 2002-08-06 | 2003-08-05 | Anti-myelin associated glycoprotein (mag) antibodies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0312456A true BR0312456A (pt) | 2005-04-19 |
Family
ID=31721633
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0312456-8A BR0312456A (pt) | 2002-08-06 | 2003-08-05 | Anticorpo alterado ou fragmento funcional do mesmo, polinucleotìdeo, sequência de polinucleotìdeo, composição farmacêutica, métodos de tratamento ou profilaxia de derrame e outras doenças/distúrbios neurológicos em um ser humano, de inibição da neurodegeneração e/ou promoção da recuperação funcional e de promoção do desenvolvimento axonial, e, uso de um anticorpo anti-mag |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US7612183B2 (enExample) |
| EP (1) | EP1526868B1 (enExample) |
| JP (1) | JP4528121B2 (enExample) |
| KR (1) | KR101078459B1 (enExample) |
| CN (1) | CN100542607C (enExample) |
| AR (1) | AR040778A1 (enExample) |
| AU (1) | AU2003255390B2 (enExample) |
| BR (1) | BR0312456A (enExample) |
| CA (1) | CA2494008C (enExample) |
| CY (1) | CY1114919T1 (enExample) |
| DK (1) | DK1526868T3 (enExample) |
| ES (1) | ES2440652T3 (enExample) |
| IL (1) | IL165478A (enExample) |
| IS (1) | IS7576A (enExample) |
| MX (1) | MXPA05001468A (enExample) |
| MY (1) | MY148409A (enExample) |
| NO (1) | NO333876B1 (enExample) |
| NZ (1) | NZ537123A (enExample) |
| PL (1) | PL211014B1 (enExample) |
| PT (1) | PT1526868E (enExample) |
| SI (1) | SI1526868T1 (enExample) |
| TW (1) | TWI323265B (enExample) |
| WO (1) | WO2004014953A2 (enExample) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7981420B2 (en) | 2000-12-22 | 2011-07-19 | Max-Planck-Gesellschaft Zur Foederung Der Wissenschaften E.V. | Therapeutic use of antibodies directed against repulsive guidance molecule (RGM) |
| GB0103174D0 (en) * | 2001-02-08 | 2001-03-28 | Smithkline Beecham Plc | Novel method of treatment |
| AR040778A1 (es) * | 2002-08-06 | 2005-04-20 | Glaxo Group Ltd | Anticuerpos alterados o fragmentos funcionales que se unen a mag (glicoproteina asociada a mielina). |
| GB0306309D0 (en) * | 2003-03-19 | 2003-04-23 | Glaxo Group Ltd | Method of treatment |
| EP2418278A3 (en) * | 2005-05-09 | 2012-07-04 | Ono Pharmaceutical Co., Ltd. | Human monoclonal antibodies to programmed death 1(PD-1) and methods for treating cancer using anti-PD-1 antibodies alone or in combination with other immunotherapeutics |
| WO2007039256A2 (de) | 2005-09-30 | 2007-04-12 | Abbott Gmbh & Co. Kg | Bindungsdomänen von proteinen der repulsive guidance molecule (rgm) proteinfamilie und funktionale fragmente davon sowie deren verwendung |
| SI2500030T2 (sl) | 2005-11-04 | 2018-11-30 | Genentech, Inc. | Uporaba inhibitorjev komplementarnih procesov za zdravljenje očesnih bolezni |
| EP2021373A4 (en) * | 2006-05-31 | 2010-06-02 | Hanwa Chemical Corp | MONOCLONAL ANTIBODY VCAM-1 SPECIFIC |
| RS58233B1 (sr) | 2006-11-02 | 2019-03-29 | Genentech Inc | Humanizovana anti-faktor d antitela i njihove upotrebe |
| WO2009051957A2 (en) * | 2007-10-16 | 2009-04-23 | Nuvelo, Inc. | Antibodies to irem-1 |
| US8962803B2 (en) | 2008-02-29 | 2015-02-24 | AbbVie Deutschland GmbH & Co. KG | Antibodies against the RGM A protein and uses thereof |
| CR20170001A (es) | 2008-04-28 | 2017-08-10 | Genentech Inc | Anticuerpos anti factor d humanizados |
| UY31809A (es) | 2008-05-06 | 2009-12-14 | Glaxo Group Ltd | Encapsulación de agentes biológicamente activos |
| TW201029662A (en) | 2008-12-19 | 2010-08-16 | Glaxo Group Ltd | Novel antigen binding proteins |
| SG172855A1 (en) * | 2009-01-29 | 2011-08-29 | Abbott Lab | Il-1 binding proteins |
| US20110165063A1 (en) * | 2009-01-29 | 2011-07-07 | Abbott Laboratories | Il-1 binding proteins |
| BR112012013734A2 (pt) | 2009-12-08 | 2017-01-10 | Abbott Gmbh & Co Kg | anticorpos monoclonais contra a proteína rgm a para uso no tratamento da degeneração da camada de fibras nervosas da retina. |
| US8663950B2 (en) | 2010-01-11 | 2014-03-04 | Arizona Board Of Regents | Production of a monoclonal antibody therapeutic against west nile virus in plants |
| TW201210612A (en) | 2010-06-03 | 2012-03-16 | Glaxo Group Ltd | Humanised antigen binding proteins |
| EP2579895A4 (en) | 2010-06-14 | 2013-12-18 | Vaccinex Inc | ANTI-VEGF ANTIBODIES AND USES THEREOF |
| US8974782B2 (en) * | 2011-02-07 | 2015-03-10 | Glaxo Group Limited | Treatment of stroke comprising anti-MAG antibodies |
| SG11201404263TA (en) | 2012-01-27 | 2014-08-28 | Abbvie Deutschland | Composition and method for diagnosis and treatment of diseases associated with neurite degeneration |
| US9308196B2 (en) * | 2012-05-18 | 2016-04-12 | Gruenenthal Gmbh | Pharmaceutical composition comprising (1 r,4r) -6'-fluoro-N ,N-dimethyl-4-phenyl-4',9'-d ihydro-3'H-spiro[cyclohexane-1,1'-pyrano-[3,4,b]indol]-4-amine and an oxicam |
| US10093978B2 (en) | 2013-08-12 | 2018-10-09 | Genentech, Inc. | Compositions for detecting complement factor H (CFH) and complement factor I (CFI) polymorphisms |
| WO2015091144A1 (en) | 2013-12-20 | 2015-06-25 | F. Hoffmann-La Roche Ag | Improved recombinant polypeptide production methods |
| CA2940579A1 (en) | 2014-03-13 | 2015-09-17 | Universitaet Basel | Carbohydrate ligands that bind to igm antibodies against myelin-associated glycoprotein |
| MX2016014160A (es) | 2014-05-01 | 2017-02-16 | Genentech Inc | Variantes del anticuerpo anti-factor d y sus usos. |
| IL302486A (en) | 2015-06-24 | 2023-06-01 | Hoffmann La Roche | Antibodies against the transnephrine receptor with adapted affinity |
| AU2016323377B2 (en) | 2015-09-16 | 2021-04-15 | Universität Basel | Carbohydrate ligands that bind to antibodies against glycoepitopes of glycosphingolipids |
| KR20180054824A (ko) * | 2015-09-29 | 2018-05-24 | 셀진 코포레이션 | Pd-1 결합 단백질 및 이의 사용 방법 |
| AR106189A1 (es) | 2015-10-02 | 2017-12-20 | Hoffmann La Roche | ANTICUERPOS BIESPECÍFICOS CONTRA EL A-b HUMANO Y EL RECEPTOR DE TRANSFERRINA HUMANO Y MÉTODOS DE USO |
| CN114057885A (zh) | 2015-10-02 | 2022-02-18 | 豪夫迈·罗氏有限公司 | 双特异性抗人cd20/人转铁蛋白受体抗体及使用方法 |
| CN108472382A (zh) | 2015-10-30 | 2018-08-31 | 豪夫迈·罗氏有限公司 | 抗-因子d抗体变体缀合物及其用途 |
| US10407510B2 (en) | 2015-10-30 | 2019-09-10 | Genentech, Inc. | Anti-factor D antibodies and conjugates |
| US10766958B2 (en) | 2016-09-19 | 2020-09-08 | Celgene Corporation | Methods of treating vitiligo using PD-1 binding antibodies |
| BR112019004733A2 (pt) | 2016-09-19 | 2019-05-28 | Celgene Corp | métodos de tratamento de distúrbios imunes usando proteínas de ligação a pd-1 |
| CN109481673A (zh) * | 2017-09-12 | 2019-03-19 | 中国科学院苏州纳米技术与纳米仿生研究所 | 促进脑损伤神经修复的组合物及其应用与评价方法 |
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| JPS57106673A (en) | 1980-12-24 | 1982-07-02 | Chugai Pharmaceut Co Ltd | Dibenzo(b,f)(1,4)oxazepin derivative |
| GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| DK84787D0 (da) | 1987-02-19 | 1987-02-19 | Axel Olsen | Listesystem til foering af elektriske stroemforsynings- og/eller svagstroemsledere |
| DE3883899T3 (de) | 1987-03-18 | 1999-04-22 | Sb2, Inc., Danville, Calif. | Geänderte antikörper. |
| US4873316A (en) | 1987-06-23 | 1989-10-10 | Biogen, Inc. | Isolation of exogenous recombinant proteins from the milk of transgenic mammals |
| US5250414A (en) | 1988-11-04 | 1993-10-05 | Erziehungsdirektion Of The Canton Zurich | Diagnostic methods using neurite growth regulatory factors |
| US5154927A (en) * | 1989-01-19 | 1992-10-13 | Wm. Wrigley Jr. Company | Gum composition containing dispersed porous beads containing active chewing gum ingredients and method |
| US5182107A (en) | 1989-09-07 | 1993-01-26 | Alkermes, Inc. | Transferrin receptor specific antibody-neuropharmaceutical or diagnostic agent conjugates |
| US5527527A (en) | 1989-09-07 | 1996-06-18 | Alkermes, Inc. | Transferrin receptor specific antibody-neuropharmaceutical agent conjugates |
| US5154924A (en) | 1989-09-07 | 1992-10-13 | Alkermes, Inc. | Transferrin receptor specific antibody-neuropharmaceutical agent conjugates |
| FI93513C (fi) | 1993-11-04 | 1995-04-25 | Matti Kangasvuori | Ketju sekä menetelmä ketjun tekemiseksi |
| AU703152B2 (en) * | 1994-01-25 | 1999-03-18 | Biogen Ma Inc. | Humanized antibodies against leukocyte adhesion molecule VLA-4 |
| GB9403250D0 (en) * | 1994-02-21 | 1994-04-13 | Univ Mcgill | Therapeutic use of myelin-associated glycoprotein (mag) |
| GB9424449D0 (en) | 1994-12-02 | 1995-01-18 | Wellcome Found | Antibodies |
| US6576607B1 (en) * | 1995-04-19 | 2003-06-10 | Acorda Therapeutics | Methods using CNS neurite outgrowth modulators |
| US5792743A (en) * | 1995-04-19 | 1998-08-11 | Acorda Therapeutics | Method for promoting neural growth comprising administering a soluble neural cell adhesion molecule |
| KR19990007893A (ko) | 1995-04-19 | 1999-01-25 | 론 코헨 | 중추신경계(cns) 축삭 성장 모듈레이터, 이를 구현 및 사용하는 조성물, 세포 및 방법 |
| CA2225691A1 (en) * | 1995-06-27 | 1997-01-16 | Research Foundation Of Cuny, Hunter College | Compositions and methods using myelin-associated glycoprotein (mag) and inhibitors thereof |
| CN1196733A (zh) * | 1995-06-30 | 1998-10-21 | 持田制药株式会社 | 抗Fas配体抗体和利用抗Fas配体抗体的测定方法 |
| US5962434A (en) | 1995-08-25 | 1999-10-05 | The Johns Hopkins University School Of Medicine | Compounds for stimulating nerve growth |
| US5834597A (en) * | 1996-05-20 | 1998-11-10 | Protein Design Labs, Inc. | Mutated nonactivating IgG2 domains and anti CD3 antibodies incorporating the same |
| US6114506A (en) * | 1996-09-20 | 2000-09-05 | General Hospital Corporation | Composition and method for enhancing fibrinolysis |
| AU748143B2 (en) * | 1997-10-28 | 2002-05-30 | University Of British Columbia, The | Immunological compositions and methods of use to transiently alter mammalian central nervous system myelin to promote neuronal regeneration |
| EP1032420A4 (en) * | 1997-11-14 | 2004-09-15 | Euro Celtique Sa | IMMUNOGLOBULIN MOLECULES WITH SYNTHETIC VARIABLE REGION AND MODIFIED SPECIFICITY |
| WO1999053945A1 (en) | 1998-04-16 | 1999-10-28 | Samuel David | Neuron growth inhibitory molecules or derivatives thereof used to immunize mammals thereby promoting axon regeneration |
| GB9809839D0 (en) | 1998-05-09 | 1998-07-08 | Glaxo Group Ltd | Antibody |
| DK1098972T3 (da) | 1998-07-22 | 2011-01-03 | Smithkline Beecham Ltd | Protein med lighed med neuroendokrinspecifikt protein samt cDNA kodende derfor |
| MXPA01002674A (es) * | 1998-09-14 | 2002-06-04 | Ostergaard Pedersen Lars | Un metodo para producir una proteina de la superfamilia de inmunoglobulina funcional. |
| ES2529196T3 (es) | 1998-11-06 | 2015-02-17 | University Of Zurich | Secuencias de nucleótidos y proteínas de genes Nogo y métodos basados en estas |
| CA2361124A1 (en) | 1999-01-22 | 2000-07-27 | Matthew John During | Vaccine-mediated treatment of neurological disorders |
| GB9908533D0 (en) | 1999-04-14 | 1999-06-09 | Novartis Ag | Organic compounds |
| US8101553B1 (en) | 2000-02-22 | 2012-01-24 | Medical & Biological Laboratories Co., Ltd. | Antibody library |
| GB0103174D0 (en) * | 2001-02-08 | 2001-03-28 | Smithkline Beecham Plc | Novel method of treatment |
| US20040002790A1 (en) * | 2002-06-28 | 2004-01-01 | Paul Senn | Sensitive devices and sensitive applications |
| AR040778A1 (es) | 2002-08-06 | 2005-04-20 | Glaxo Group Ltd | Anticuerpos alterados o fragmentos funcionales que se unen a mag (glicoproteina asociada a mielina). |
| GB0306309D0 (en) * | 2003-03-19 | 2003-04-23 | Glaxo Group Ltd | Method of treatment |
-
2003
- 2003-08-04 AR AR20030102790A patent/AR040778A1/es not_active Application Discontinuation
- 2003-08-04 TW TW092121286A patent/TWI323265B/zh not_active IP Right Cessation
- 2003-08-05 AU AU2003255390A patent/AU2003255390B2/en not_active Ceased
- 2003-08-05 WO PCT/EP2003/008749 patent/WO2004014953A2/en not_active Ceased
- 2003-08-05 MY MYPI20032945A patent/MY148409A/en unknown
- 2003-08-05 CN CNB03818477XA patent/CN100542607C/zh not_active Expired - Fee Related
- 2003-08-05 CA CA2494008A patent/CA2494008C/en not_active Expired - Fee Related
- 2003-08-05 MX MXPA05001468A patent/MXPA05001468A/es active IP Right Grant
- 2003-08-05 KR KR1020057002132A patent/KR101078459B1/ko not_active Expired - Fee Related
- 2003-08-05 EP EP03784195.4A patent/EP1526868B1/en not_active Expired - Lifetime
- 2003-08-05 PT PT37841954T patent/PT1526868E/pt unknown
- 2003-08-05 JP JP2004526901A patent/JP4528121B2/ja not_active Expired - Fee Related
- 2003-08-05 SI SI200332328T patent/SI1526868T1/sl unknown
- 2003-08-05 NZ NZ537123A patent/NZ537123A/en not_active IP Right Cessation
- 2003-08-05 US US10/523,295 patent/US7612183B2/en not_active Expired - Fee Related
- 2003-08-05 BR BR0312456-8A patent/BR0312456A/pt not_active IP Right Cessation
- 2003-08-05 DK DK03784195.4T patent/DK1526868T3/da active
- 2003-08-05 PL PL375405A patent/PL211014B1/pl unknown
- 2003-08-05 ES ES03784195.4T patent/ES2440652T3/es not_active Expired - Lifetime
-
2004
- 2004-11-30 IL IL165478A patent/IL165478A/en not_active IP Right Cessation
- 2004-11-30 IS IS7576A patent/IS7576A/is unknown
- 2004-12-03 NO NO20045323A patent/NO333876B1/no not_active IP Right Cessation
-
2008
- 2008-04-01 US US12/060,555 patent/US8071731B2/en not_active Expired - Fee Related
-
2014
- 2014-01-14 CY CY20141100027T patent/CY1114919T1/el unknown
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