BR0116169A - Composto, composição farmacêutica que compreende esse composto, processo para a preparação de uma composição farmacêutica, utilização dos compostos, processo para o tratamento profilático ou terapêutico de diabetes do tipo ii e processo para a preparação do composto. - Google Patents

Composto, composição farmacêutica que compreende esse composto, processo para a preparação de uma composição farmacêutica, utilização dos compostos, processo para o tratamento profilático ou terapêutico de diabetes do tipo ii e processo para a preparação do composto.

Info

Publication number
BR0116169A
BR0116169A BR0116169-5A BR0116169A BR0116169A BR 0116169 A BR0116169 A BR 0116169A BR 0116169 A BR0116169 A BR 0116169A BR 0116169 A BR0116169 A BR 0116169A
Authority
BR
Brazil
Prior art keywords
compound
pharmaceutical composition
type
diabetes
compounds
Prior art date
Application number
BR0116169-5A
Other languages
English (en)
Inventor
Kevin Richard Guertin
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BR0116169A publication Critical patent/BR0116169A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Abstract

"COMPOSTO, COMPOSIçãO FARMACêUTICA QUE COMPREENDE ESSE COMPOSTO, PROCESSO PARA A PREPARAçãO DE UMA COMPOSIçãO FARMACêUTICA, UTILIZAçãO DOS COMPOSTOS, PROCESSO PARA O TRATAMENTO PROFILáTICO OU TERAPêUTICO DE DIABETES DO TIPO II E PROCESSO PARA A PREPARAçãO DO COMPOSTO". Expõem-se estimuladores de glicoquinase de propionamida isoindolin-1-ona-substituída, os quais aumentam a secreção de insulina no tratamento de diabetes do tipo II.
BR0116169-5A 2000-12-13 2001-12-07 Composto, composição farmacêutica que compreende esse composto, processo para a preparação de uma composição farmacêutica, utilização dos compostos, processo para o tratamento profilático ou terapêutico de diabetes do tipo ii e processo para a preparação do composto. BR0116169A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25527300P 2000-12-13 2000-12-13
US31871501P 2001-09-13 2001-09-13
PCT/EP2001/014404 WO2002048106A2 (en) 2000-12-13 2001-12-07 Isoindolin-1-one glucokinase activators

Publications (1)

Publication Number Publication Date
BR0116169A true BR0116169A (pt) 2003-12-23

Family

ID=26944583

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0116169-5A BR0116169A (pt) 2000-12-13 2001-12-07 Composto, composição farmacêutica que compreende esse composto, processo para a preparação de uma composição farmacêutica, utilização dos compostos, processo para o tratamento profilático ou terapêutico de diabetes do tipo ii e processo para a preparação do composto.

Country Status (36)

Country Link
US (1) US6482951B2 (pt)
EP (1) EP1349856B1 (pt)
JP (1) JP4021766B2 (pt)
KR (1) KR100520651B1 (pt)
CN (1) CN1247574C (pt)
AT (1) ATE297922T1 (pt)
AU (2) AU3841502A (pt)
BG (1) BG107903A (pt)
BR (1) BR0116169A (pt)
CA (1) CA2430579C (pt)
CY (1) CY1105587T1 (pt)
CZ (1) CZ20031882A3 (pt)
DE (1) DE60111570T2 (pt)
DK (1) DK1349856T3 (pt)
EG (1) EG24358A (pt)
ES (1) ES2243578T3 (pt)
HK (1) HK1063314A1 (pt)
HR (1) HRP20030450B1 (pt)
HU (1) HUP0400587A3 (pt)
IL (2) IL156264A0 (pt)
MA (1) MA26973A1 (pt)
MX (1) MXPA03005170A (pt)
MY (1) MY136741A (pt)
NO (1) NO325810B1 (pt)
NZ (1) NZ526236A (pt)
PA (1) PA8534601A1 (pt)
PE (1) PE20020593A1 (pt)
PL (1) PL366006A1 (pt)
PT (1) PT1349856E (pt)
RS (1) RS50933B (pt)
RU (1) RU2249590C2 (pt)
SI (1) SI1349856T1 (pt)
SK (1) SK8732003A3 (pt)
TW (1) TWI294876B (pt)
UY (1) UY27069A1 (pt)
WO (1) WO2002048106A2 (pt)

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SE0102764D0 (sv) 2001-08-17 2001-08-17 Astrazeneca Ab Compounds
BR0314864A (pt) 2002-10-03 2005-08-02 Novartis Ag Compostos orgânicos
DK1549638T3 (da) 2002-10-03 2008-01-21 Hoffmann La Roche Indol-3-carboxamider som glucokinase (GK) aktivatorer
GB0226931D0 (en) 2002-11-19 2002-12-24 Astrazeneca Ab Chemical compounds
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WO2004072066A1 (en) * 2003-02-11 2004-08-26 Prosidion Limited Tri(cyclo) substituted amide glucokinase activator compounds
PL378117A1 (pl) * 2003-02-11 2006-03-06 Prosidion Limited Tricyklopodstawione związki amidowe
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MXPA06011365A (es) * 2004-04-02 2006-12-15 Novartis Ag Derivados de tiazolo-piridina, composiciones farmaceuticas que los contienen, y metodos para el tratamiento de condiciones mediadas por glucoquinasa.
BRPI0509573A (pt) 2004-04-02 2007-09-25 Novartis Ag derivados de sulfonamida-tiazolpiridina como ativadores de glicocinase úteis para o tratamento de diabetes do tipo 2
US20090281142A1 (en) * 2005-08-31 2009-11-12 Astellas Pharma Inc. Thiazole derivative
JP2007063225A (ja) 2005-09-01 2007-03-15 Takeda Chem Ind Ltd イミダゾピリジン化合物
WO2007039177A2 (en) 2005-09-29 2007-04-12 Sanofi-Aventis Phenyl- and pyridinyl- 1, 2 , 4 - oxadiazolone derivatives, processes for their preparation and their use as pharmaceuticals
GT200600428A (es) * 2005-09-30 2007-05-21 Compuestos organicos
GT200600429A (es) * 2005-09-30 2007-04-30 Compuestos organicos
US8796313B2 (en) 2005-11-01 2014-08-05 Janssen Pharmaceutica N.V. Substituted dihydroisoindolones as allosteric modulators of glucokinase
JP2009518286A (ja) * 2005-11-01 2009-05-07 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ グルコキナーゼのアロステリックモジュレーターとしてのジヒドロイソインドロン
WO2007053657A1 (en) * 2005-11-01 2007-05-10 Janssen Pharmaceutica N.V. Substituted pyrrolones as allosteric modulators of glucokinase
CN101321747A (zh) * 2005-11-01 2008-12-10 詹森药业有限公司 作为葡萄糖激酶变构调节剂的取代的环烷基吡咯酮类
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EP2231640B1 (en) * 2008-01-24 2012-06-06 Merck Patent GmbH Beta-amino acid derivatives for treatment of diabetes
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Also Published As

Publication number Publication date
NO20032674L (no) 2003-06-12
CZ20031882A3 (cs) 2003-12-17
TWI294876B (en) 2008-03-21
EP1349856B1 (en) 2005-06-15
RU2249590C2 (ru) 2005-04-10
SK8732003A3 (en) 2004-04-06
BG107903A (bg) 2004-02-27
HUP0400587A3 (en) 2011-03-28
CY1105587T1 (el) 2010-07-28
US20020082260A1 (en) 2002-06-27
NO325810B1 (no) 2008-07-21
DK1349856T3 (da) 2005-10-17
HRP20030450B1 (en) 2006-02-28
WO2002048106A3 (en) 2002-11-28
US6482951B2 (en) 2002-11-19
IL156264A (en) 2010-11-30
MY136741A (en) 2008-11-28
UY27069A1 (es) 2002-07-31
PL366006A1 (en) 2005-01-24
NZ526236A (en) 2004-12-24
CN1247574C (zh) 2006-03-29
HUP0400587A2 (hu) 2004-06-28
HK1063314A1 (en) 2004-12-24
AU3841502A (en) 2002-06-24
DE60111570T2 (de) 2006-05-11
CN1481382A (zh) 2004-03-10
YU47703A (sh) 2006-05-25
ES2243578T3 (es) 2005-12-01
KR20030064817A (ko) 2003-08-02
AU2002238415B2 (en) 2007-01-04
EP1349856A2 (en) 2003-10-08
NO20032674D0 (no) 2003-06-12
PT1349856E (pt) 2005-09-30
KR100520651B1 (ko) 2005-10-11
JP2004521095A (ja) 2004-07-15
RS50933B (sr) 2010-08-31
MA26973A1 (fr) 2004-12-20
DE60111570D1 (de) 2005-07-21
JP4021766B2 (ja) 2007-12-12
ATE297922T1 (de) 2005-07-15
SI1349856T1 (en) 2005-10-31
CA2430579A1 (en) 2002-06-20
EG24358A (en) 2009-03-04
CA2430579C (en) 2010-01-26
WO2002048106A2 (en) 2002-06-20
PE20020593A1 (es) 2002-07-06
HRP20030450A2 (en) 2005-04-30
MXPA03005170A (es) 2003-09-22
IL156264A0 (en) 2004-01-04
PA8534601A1 (es) 2002-08-26

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