BR0214615A - Composto hexacìclico - Google Patents

Composto hexacìclico

Info

Publication number
BR0214615A
BR0214615A BR0214615-0A BR0214615A BR0214615A BR 0214615 A BR0214615 A BR 0214615A BR 0214615 A BR0214615 A BR 0214615A BR 0214615 A BR0214615 A BR 0214615A
Authority
BR
Brazil
Prior art keywords
hexacyclic compound
hexacyclic
compound
compounds
useful
Prior art date
Application number
BR0214615-0A
Other languages
English (en)
Portuguese (pt)
Inventor
Takeshi Murata
Satoshi Niizuma
Nobuo Shimma
Hitomi Suda
Masao Tsukasaki
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of BR0214615A publication Critical patent/BR0214615A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BR0214615-0A 2001-11-30 2002-11-25 Composto hexacìclico BR0214615A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01128361 2001-11-30
PCT/EP2002/013216 WO2003045952A2 (en) 2001-11-30 2002-11-25 Condensed camptothecins as antitumor agents

Publications (1)

Publication Number Publication Date
BR0214615A true BR0214615A (pt) 2004-09-14

Family

ID=8179394

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0214615-0A BR0214615A (pt) 2001-11-30 2002-11-25 Composto hexacìclico

Country Status (28)

Country Link
US (2) US6825194B2 (OSRAM)
EP (1) EP1480984B9 (OSRAM)
JP (1) JP4305909B2 (OSRAM)
KR (1) KR100895746B1 (OSRAM)
CN (1) CN100338066C (OSRAM)
AT (1) ATE398131T1 (OSRAM)
AU (1) AU2002356720B2 (OSRAM)
BR (1) BR0214615A (OSRAM)
CA (1) CA2468824C (OSRAM)
DE (1) DE60227113D1 (OSRAM)
ES (1) ES2307830T3 (OSRAM)
GT (1) GT200200250A (OSRAM)
HU (1) HUP0500062A3 (OSRAM)
IL (1) IL162058A0 (OSRAM)
MX (1) MXPA04005185A (OSRAM)
MY (1) MY136138A (OSRAM)
NO (1) NO329005B1 (OSRAM)
NZ (1) NZ533568A (OSRAM)
PA (1) PA8558901A1 (OSRAM)
PE (1) PE20030725A1 (OSRAM)
PL (1) PL207510B1 (OSRAM)
RS (1) RS51051B (OSRAM)
RU (1) RU2299212C2 (OSRAM)
TW (1) TWI258481B (OSRAM)
UA (1) UA80409C2 (OSRAM)
UY (1) UY27560A1 (OSRAM)
WO (1) WO2003045952A2 (OSRAM)
ZA (1) ZA200404522B (OSRAM)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004073601A2 (en) * 2003-02-21 2004-09-02 Chugai Seiyaku Kabushiki Kaisha Process for the preparation of hexacyclic camptothecin derivatives
EP1757609B1 (en) 2004-04-09 2013-10-16 Chugai Seiyaku Kabushiki Kaisha Novel water-soluble prodrug
TW200744603A (en) 2005-08-22 2007-12-16 Chugai Pharmaceutical Co Ltd Novel anticancer concomitant drug
CA2626330A1 (en) * 2005-10-19 2007-04-26 Chugai Seiyaku Kabushiki Kaisha Preventive or therapeutic agents for pancreatic cancer, ovarian cancer, or liver cancer comprising a novel water-solube prodrug
RU2439073C1 (ru) * 2010-07-13 2012-01-10 Государственное образовательное учреждение высшего профессионального образования "Кубанский государственный технологический университет" (ГОУ ВПО "КубГТУ") СПОСОБ ПОЛУЧЕНИЯ ПРОИЗВОДНЫХ ИНДОЛИЗИНО[7,6-b]ИНДОЛА
PH12021552363A1 (en) 2019-03-29 2022-09-05 Medimmune Ltd Compounds and conjugates thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4473692A (en) 1981-09-04 1984-09-25 Kabushiki Kaisha Yakult Honsha Camptothecin derivatives and process for preparing same
US4939255A (en) * 1987-06-24 1990-07-03 Daiichi Pharmaceutical Co., Ltd. Hexa-cyclic camptothecin derivatives
HU213136B (en) * 1990-08-14 1997-02-28 Kyorin Seiyaku Kk Process for producing fluoroethyl camptothecin derivatives and pharmaceutical compositions containing them
JP3008226B2 (ja) * 1991-01-16 2000-02-14 第一製薬株式会社 六環性化合物
JP3359955B2 (ja) * 1992-07-16 2002-12-24 第一製薬株式会社 抗腫瘍剤
GB9402934D0 (en) * 1994-02-16 1994-04-06 Erba Carlo Spa Camptothecin derivatives and process for their preparation
US5663177A (en) * 1995-05-31 1997-09-02 Smithkline Beecham Corporation Water soluble camptothecin analogs
CA2280905C (en) 1997-02-14 2006-08-29 Bionumerik Pharmaceuticals, Inc. Highly lipophilic camptothecin derivatives
GB9715821D0 (en) * 1997-07-25 1997-10-01 Pharmacia & Upjohn Spa Amidino-camptothecin derivatives

Also Published As

Publication number Publication date
UY27560A1 (es) 2003-05-30
RS47004A (sr) 2007-02-05
MXPA04005185A (es) 2004-08-11
NO329005B1 (no) 2010-07-19
ES2307830T3 (es) 2008-12-01
GT200200250A (es) 2004-01-15
PE20030725A1 (es) 2003-08-28
TW200408642A (en) 2004-06-01
US20050059679A1 (en) 2005-03-17
ATE398131T1 (de) 2008-07-15
JP4305909B2 (ja) 2009-07-29
RU2004119841A (ru) 2005-03-27
HUP0500062A3 (en) 2012-12-28
RU2299212C2 (ru) 2007-05-20
UA80409C2 (en) 2007-09-25
WO2003045952A3 (en) 2003-10-16
US20030144304A1 (en) 2003-07-31
PL370479A1 (en) 2005-05-30
CN1617874A (zh) 2005-05-18
CN100338066C (zh) 2007-09-19
US7109195B2 (en) 2006-09-19
HK1077303A1 (en) 2006-02-10
EP1480984A2 (en) 2004-12-01
AU2002356720A1 (en) 2003-06-10
PA8558901A1 (es) 2003-06-30
KR20040062976A (ko) 2004-07-09
MY136138A (en) 2008-08-29
AU2002356720B2 (en) 2009-01-29
HK1072935A1 (en) 2005-09-16
NZ533568A (en) 2006-01-27
HUP0500062A2 (hu) 2005-04-28
EP1480984B9 (en) 2009-03-11
TWI258481B (en) 2006-07-21
ZA200404522B (en) 2005-01-04
JP2005511643A (ja) 2005-04-28
IL162058A0 (en) 2005-11-20
NO20042729L (no) 2004-08-27
CA2468824C (en) 2011-01-11
DE60227113D1 (de) 2008-07-24
RS51051B (sr) 2010-10-31
WO2003045952A2 (en) 2003-06-05
EP1480984B1 (en) 2008-06-11
KR100895746B1 (ko) 2009-04-30
US6825194B2 (en) 2004-11-30
CA2468824A1 (en) 2003-06-05
PL207510B1 (pl) 2010-12-31

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 11A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2259 DE 22/04/2014.