NO20042729L - Heksasykliske forbindelser - Google Patents

Heksasykliske forbindelser

Info

Publication number
NO20042729L
NO20042729L NO20042729A NO20042729A NO20042729L NO 20042729 L NO20042729 L NO 20042729L NO 20042729 A NO20042729 A NO 20042729A NO 20042729 A NO20042729 A NO 20042729A NO 20042729 L NO20042729 L NO 20042729L
Authority
NO
Norway
Prior art keywords
sup
compounds
hexycyclic
identified
useful
Prior art date
Application number
NO20042729A
Other languages
English (en)
Other versions
NO329005B1 (no
Inventor
Nobuo Shimma
Takeshi Murata
Satoshi Niizuma
Hitomi Suda
Masao Tsukazaki
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of NO20042729L publication Critical patent/NO20042729L/no
Publication of NO329005B1 publication Critical patent/NO329005B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO20042729A 2001-11-30 2004-06-29 Heksasykliske forbindelser, farmasoytiske preparater som omfatter forbindelsene, anvendelser av forbindelsene til fremstilling av medikamenter samt fremgangsmate for fremstilling av forbindelsene og fremgangsmater for fremstilling av mellomprodukter NO329005B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01128361 2001-11-30
PCT/EP2002/013216 WO2003045952A2 (en) 2001-11-30 2002-11-25 Condensed camptothecins as antitumor agents

Publications (2)

Publication Number Publication Date
NO20042729L true NO20042729L (no) 2004-08-27
NO329005B1 NO329005B1 (no) 2010-07-19

Family

ID=8179394

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20042729A NO329005B1 (no) 2001-11-30 2004-06-29 Heksasykliske forbindelser, farmasoytiske preparater som omfatter forbindelsene, anvendelser av forbindelsene til fremstilling av medikamenter samt fremgangsmate for fremstilling av forbindelsene og fremgangsmater for fremstilling av mellomprodukter

Country Status (28)

Country Link
US (2) US6825194B2 (no)
EP (1) EP1480984B9 (no)
JP (1) JP4305909B2 (no)
KR (1) KR100895746B1 (no)
CN (1) CN100338066C (no)
AT (1) ATE398131T1 (no)
AU (1) AU2002356720B2 (no)
BR (1) BR0214615A (no)
CA (1) CA2468824C (no)
DE (1) DE60227113D1 (no)
ES (1) ES2307830T3 (no)
GT (1) GT200200250A (no)
HU (1) HUP0500062A3 (no)
IL (1) IL162058A0 (no)
MX (1) MXPA04005185A (no)
MY (1) MY136138A (no)
NO (1) NO329005B1 (no)
NZ (1) NZ533568A (no)
PA (1) PA8558901A1 (no)
PE (1) PE20030725A1 (no)
PL (1) PL207510B1 (no)
RS (1) RS51051B (no)
RU (1) RU2299212C2 (no)
TW (1) TWI258481B (no)
UA (1) UA80409C2 (no)
UY (1) UY27560A1 (no)
WO (1) WO2003045952A2 (no)
ZA (1) ZA200404522B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7595400B2 (en) 2003-02-21 2009-09-29 Chugai Seiyaku Kabushiki Kaisha Process for the preparation of hexacyclic compounds
US7910593B2 (en) 2004-04-09 2011-03-22 Chugai Seiyaku Kabushiki Kaisha Water-soluble prodrugs
TW200744603A (en) * 2005-08-22 2007-12-16 Chugai Pharmaceutical Co Ltd Novel anticancer concomitant drug
WO2007046456A1 (ja) * 2005-10-19 2007-04-26 Chugai Seiyaku Kabushiki Kaisha 新規水溶性プロドラッグを含有する、膵臓癌、卵巣癌または肝臓癌の予防または治療剤
RU2439073C1 (ru) * 2010-07-13 2012-01-10 Государственное образовательное учреждение высшего профессионального образования "Кубанский государственный технологический университет" (ГОУ ВПО "КубГТУ") СПОСОБ ПОЛУЧЕНИЯ ПРОИЗВОДНЫХ ИНДОЛИЗИНО[7,6-b]ИНДОЛА
CN118221763A (zh) 2019-03-29 2024-06-21 免疫医疗有限公司 化合物及其缀合物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4473692A (en) 1981-09-04 1984-09-25 Kabushiki Kaisha Yakult Honsha Camptothecin derivatives and process for preparing same
US4939255A (en) * 1987-06-24 1990-07-03 Daiichi Pharmaceutical Co., Ltd. Hexa-cyclic camptothecin derivatives
HU213136B (en) * 1990-08-14 1997-02-28 Kyorin Seiyaku Kk Process for producing fluoroethyl camptothecin derivatives and pharmaceutical compositions containing them
JP3008226B2 (ja) * 1991-01-16 2000-02-14 第一製薬株式会社 六環性化合物
JP3359955B2 (ja) * 1992-07-16 2002-12-24 第一製薬株式会社 抗腫瘍剤
GB9402934D0 (en) * 1994-02-16 1994-04-06 Erba Carlo Spa Camptothecin derivatives and process for their preparation
US5663177A (en) * 1995-05-31 1997-09-02 Smithkline Beecham Corporation Water soluble camptothecin analogs
CA2280905C (en) 1997-02-14 2006-08-29 Bionumerik Pharmaceuticals, Inc. Highly lipophilic camptothecin derivatives
GB9715821D0 (en) * 1997-07-25 1997-10-01 Pharmacia & Upjohn Spa Amidino-camptothecin derivatives

Also Published As

Publication number Publication date
UA80409C2 (en) 2007-09-25
TW200408642A (en) 2004-06-01
IL162058A0 (en) 2005-11-20
JP4305909B2 (ja) 2009-07-29
ZA200404522B (en) 2005-01-04
AU2002356720B2 (en) 2009-01-29
PE20030725A1 (es) 2003-08-28
AU2002356720A1 (en) 2003-06-10
CA2468824A1 (en) 2003-06-05
KR20040062976A (ko) 2004-07-09
ATE398131T1 (de) 2008-07-15
CN1617874A (zh) 2005-05-18
RS47004A (sr) 2007-02-05
EP1480984B1 (en) 2008-06-11
UY27560A1 (es) 2003-05-30
GT200200250A (es) 2004-01-15
NZ533568A (en) 2006-01-27
JP2005511643A (ja) 2005-04-28
RU2004119841A (ru) 2005-03-27
RS51051B (sr) 2010-10-31
WO2003045952A2 (en) 2003-06-05
PL207510B1 (pl) 2010-12-31
HUP0500062A3 (en) 2012-12-28
MXPA04005185A (es) 2004-08-11
HK1077303A1 (en) 2006-02-10
PA8558901A1 (es) 2003-06-30
US20030144304A1 (en) 2003-07-31
KR100895746B1 (ko) 2009-04-30
BR0214615A (pt) 2004-09-14
CA2468824C (en) 2011-01-11
US7109195B2 (en) 2006-09-19
NO329005B1 (no) 2010-07-19
US6825194B2 (en) 2004-11-30
DE60227113D1 (de) 2008-07-24
PL370479A1 (en) 2005-05-30
RU2299212C2 (ru) 2007-05-20
HUP0500062A2 (hu) 2005-04-28
ES2307830T3 (es) 2008-12-01
CN100338066C (zh) 2007-09-19
MY136138A (en) 2008-08-29
WO2003045952A3 (en) 2003-10-16
US20050059679A1 (en) 2005-03-17
EP1480984A2 (en) 2004-12-01
TWI258481B (en) 2006-07-21
HK1072935A1 (en) 2005-09-16
EP1480984B9 (en) 2009-03-11

Similar Documents

Publication Publication Date Title
SE0202463D0 (sv) Novel compounds
MY135841A (en) Novel benzodioxoles
JO2282B1 (en) Oxazole derivatives
AP2002002637A0 (en) Novel piperazine
EA200501009A1 (ru) Замещённые пирролопиразольные производные в качестве ингибиторов киназы
BG106013A (en) New compounds and compositions as protease inhibitors
EA200500174A1 (ru) Новые производные бензимидазола, полезные в качестве антипролиферативных агентов
DE60045508D1 (de) Dalda-analoge und ihre verwendung
DE60324544D1 (de) Muskarin antagonisten
SE0104250D0 (sv) Heterocyclic compounds
PE20030061A1 (es) 1-biaril-1,8-naftiridin-4-ona como inhibidores de fosfodiesterasa-4
SE9803518D0 (sv) Novel compounds
SE9802208D0 (sv) Novel compounds
PT992509E (pt) Novos derivados macrolidos
SE0102055D0 (sv) New Compounds
MXPA04006041A (es) Antivirales de piridoquinoxalina.
SE0302756D0 (sv) Novel Compounds
SE0203070D0 (en) Novel compounds
AU2001290480A1 (en) Cyclized benzamide neurokinin antagonists for use in therapy
FI970469A0 (fi) Bentsimidatsolijohdannaisia, joilla on dopaminerginen aktiivisuus
SE9803773D0 (sv) Compounds
CA2356985A1 (en) 5ht1 antagonists for antidepressant therapy
NO20042729L (no) Heksasykliske forbindelser
SE9802209D0 (sv) Novel compounds
ATE324368T1 (de) Heteroarylheteroalkylamin derivate und deren verwendung als inhibitoren der stickoxidsynthase

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees