BR0212026A - Sistema terapêutico transdérmico com fentanila ou substâncias análogas - Google Patents

Sistema terapêutico transdérmico com fentanila ou substâncias análogas

Info

Publication number
BR0212026A
BR0212026A BR0212026-7A BR0212026A BR0212026A BR 0212026 A BR0212026 A BR 0212026A BR 0212026 A BR0212026 A BR 0212026A BR 0212026 A BR0212026 A BR 0212026A
Authority
BR
Brazil
Prior art keywords
fentanyl
therapeutic system
transdermal therapeutic
weight
active substance
Prior art date
Application number
BR0212026-7A
Other languages
English (en)
Inventor
Walter Mueller
Thomas Hille
Original Assignee
Lohmann Therapie Syst Lts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7696568&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0212026(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lohmann Therapie Syst Lts filed Critical Lohmann Therapie Syst Lts
Publication of BR0212026A publication Critical patent/BR0212026A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

"SISTEMA TERAPêUTICO TRANSDéRMICO COM FENTANILA OU SUBSTâNCIAS ANáLOGAS". A invenção refere-se a um sistema terapêutico transdérmico (TTS), que consiste em uma camada posterior, que é impermeável para a substância ativa, pelo menos uma camada de matriz, que contém fentanila ou uma substância ativa análoga à fentanila, com base em poliacrilato, e uma camada de proteção, a ser removida antes do uso, caracterizado pelo fato de que o polímero de poliacrilato é auto-adesivo e livre de grupos carboxila, apresenta uma solubilidade de saturação para fentanila entre 3 e 20% em peso, preferivelmente, uma solubilidade de saturação de 4 a 12 e, de modo particularmente preferido, uma solubilidade de saturação entre 5 e 10% em peso e as camadas contêm pelo menos 80% em peso da substância ativa incorporada, em forma dissolvida de modo molecularmente disperso.
BR0212026-7A 2001-08-24 2002-07-10 Sistema terapêutico transdérmico com fentanila ou substâncias análogas BR0212026A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10141650A DE10141650C1 (de) 2001-08-24 2001-08-24 Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
PCT/EP2002/007664 WO2003018075A2 (de) 2001-08-24 2002-07-10 Transdermales therapeutisches system mit fentanyl bzw. verwandten substanzen

Publications (1)

Publication Number Publication Date
BR0212026A true BR0212026A (pt) 2004-08-03

Family

ID=7696568

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0212026-7A BR0212026A (pt) 2001-08-24 2002-07-10 Sistema terapêutico transdérmico com fentanila ou substâncias análogas

Country Status (17)

Country Link
US (3) US10568845B2 (pt)
EP (3) EP1418894B1 (pt)
JP (2) JP5405709B2 (pt)
KR (1) KR100895189B1 (pt)
CN (2) CN1713899A (pt)
AT (1) ATE352293T1 (pt)
AU (1) AU2002328328B2 (pt)
BR (1) BR0212026A (pt)
CA (1) CA2457401C (pt)
CY (1) CY1106411T1 (pt)
DE (2) DE10141650C1 (pt)
DK (1) DK1418894T3 (pt)
ES (1) ES2280563T3 (pt)
MX (1) MXPA04001676A (pt)
PT (1) PT1418894E (pt)
WO (1) WO2003018075A2 (pt)
ZA (1) ZA200400314B (pt)

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CN107106552A (zh) * 2014-12-19 2017-08-29 3M创新有限公司 包含芬太尼的透皮药物递送装置
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US10583093B2 (en) 2020-03-10
ES2280563T3 (es) 2007-09-16
EP1782799A2 (de) 2007-05-09
CN102258501A (zh) 2011-11-30
JP2011006493A (ja) 2011-01-13
MXPA04001676A (es) 2004-05-31
KR100895189B1 (ko) 2009-04-24
US10568845B2 (en) 2020-02-25
EP1418894B1 (de) 2007-01-24
JP2005501111A (ja) 2005-01-13
PT1418894E (pt) 2007-04-30
WO2003018075A2 (de) 2003-03-06
ATE352293T1 (de) 2007-02-15
DE10141650C1 (de) 2002-11-28
WO2003018075A3 (de) 2003-11-20
AU2002328328B2 (en) 2007-03-15
US20200206148A1 (en) 2020-07-02
CY1106411T1 (el) 2011-10-12
US20040234584A1 (en) 2004-11-25
EP1825849A1 (de) 2007-08-29
US10940122B2 (en) 2021-03-09
EP1418894A2 (de) 2004-05-19
DE50209364D1 (en) 2007-03-15
KR20040029007A (ko) 2004-04-03
DK1418894T3 (da) 2007-04-10
CN1713899A (zh) 2005-12-28
CA2457401A1 (en) 2003-03-06
ZA200400314B (en) 2004-11-01
EP1782799A3 (de) 2007-05-16
JP5405709B2 (ja) 2014-02-05
JP5639843B2 (ja) 2014-12-10
US20190262277A1 (en) 2019-08-29
CA2457401C (en) 2010-09-07

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