BR0116531A - Composição farmacêutica, kit e uso de um composto - Google Patents

Composição farmacêutica, kit e uso de um composto

Info

Publication number
BR0116531A
BR0116531A BR0116531-3A BR0116531A BR0116531A BR 0116531 A BR0116531 A BR 0116531A BR 0116531 A BR0116531 A BR 0116531A BR 0116531 A BR0116531 A BR 0116531A
Authority
BR
Brazil
Prior art keywords
kit
compound
pharmaceutical composition
tetrahydrothieno
cyclopropylcarbonyl
Prior art date
Application number
BR0116531-3A
Other languages
English (en)
Inventor
Fumitoshi Asai
Atsuhiro Sugidachi
Taketoshi Ogawa
Teruhiko Inoue
Original Assignee
Sankyo Co
Ube Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=18858878&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0116531(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sankyo Co, Ube Industries filed Critical Sankyo Co
Publication of BR0116531A publication Critical patent/BR0116531A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

"COMPOSIçãO FARMACêUTICA, KIT E USO DE UM COMPOSTO". Composições medicinais contendo, como ingredientes ativos, 2-acetoxi-5-(<244>-ciclopropilcarbonil-2-fluorobenzil)-4,5,6,7-tetraidr otieno [3,2-c]piridina ou seu sal farmacologicamente aceitável e aspirina. Devido a ter excelentes efeitos inibidores sobre a agregação de plaquetas e trombose, estas composições são utilizáveis como preventivos ou remédios para doenças induzidas por trombos ou embolização.
BR0116531-3A 2000-12-25 2001-12-20 Composição farmacêutica, kit e uso de um composto BR0116531A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000392983 2000-12-25
PCT/JP2001/011201 WO2002051412A1 (fr) 2000-12-25 2001-12-20 Compositions medicales contenant de l'aspirine

Publications (1)

Publication Number Publication Date
BR0116531A true BR0116531A (pt) 2004-02-25

Family

ID=18858878

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0116531-3A BR0116531A (pt) 2000-12-25 2001-12-20 Composição farmacêutica, kit e uso de um composto

Country Status (26)

Country Link
US (3) US20040024013A1 (pt)
EP (1) EP1350511B1 (pt)
KR (1) KR100692934B1 (pt)
CN (1) CN100341506C (pt)
AT (1) ATE407675T1 (pt)
AU (1) AU2002217464B2 (pt)
BR (1) BR0116531A (pt)
CA (1) CA2432644C (pt)
CY (1) CY1108626T1 (pt)
CZ (1) CZ297570B6 (pt)
DE (1) DE60135780D1 (pt)
DK (1) DK1350511T3 (pt)
ES (1) ES2311498T3 (pt)
HK (1) HK1056118A1 (pt)
HU (1) HUP0400644A3 (pt)
IL (2) IL156456A0 (pt)
MX (1) MXPA03005770A (pt)
NO (1) NO20032902L (pt)
NZ (1) NZ526540A (pt)
PL (1) PL206138B1 (pt)
PT (1) PT1350511E (pt)
RU (1) RU2262933C2 (pt)
SK (1) SK287972B6 (pt)
TW (1) TWI293249B (pt)
WO (1) WO2002051412A1 (pt)
ZA (1) ZA200304878B (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20090033917A (ko) * 2000-07-06 2009-04-06 다이이찌 산쿄 가부시키가이샤 히드로피리딘 유도체 산부가염
DE60135780D1 (de) 2000-12-25 2008-10-23 Daiichi Sankyo Co Ltd Aspirin enthaltende medizinische zusammensetzungen
EP1660183A2 (en) * 2003-05-05 2006-05-31 Eli Lilly and Company Treating cardiovascular diseases with a compound of formula 1 (cs 747 - prasugrel; rn 150322-43-4)
CN100488163C (zh) * 2005-01-19 2009-05-13 华为技术有限公司 组播业务处理方法和系统
KR20080016647A (ko) * 2005-06-17 2008-02-21 일라이 릴리 앤드 캄파니 프라수그렐에 대한 투여 계획
DE102005029612A1 (de) * 2005-06-23 2007-01-04 Hochschule Bremen Vorrichtung zum Erzeugen eines Panoramabildes
EP1940399A2 (en) * 2005-08-19 2008-07-09 Eli Lilly & Company Use of par-i/par- 4 inhibitors for treating or preventing vascular diseases
PL2032521T3 (pl) * 2006-06-27 2010-05-31 Sandoz Ag Nowy sposób wytwarzania soli
CA2672157C (en) * 2006-12-07 2016-07-26 Daiichi Sankyo Company, Limited Method for producing solid preparation
TWI482641B (zh) * 2006-12-07 2015-05-01 Daiichi Sankyo Co Ltd 含有低取代度羥丙基纖維素之醫藥組成物
US20100280064A1 (en) * 2006-12-07 2010-11-04 Tomoyuki Watanabe Pharmaceutical composition having improved storage stability
EP2100606A4 (en) * 2006-12-07 2009-12-30 Daiichi Sankyo Co Ltd COATED PREPARATION OF A FILM HAVING IMPROVED STABILITY
TWI428151B (zh) * 2006-12-07 2014-03-01 Daiichi Sankyo Co Ltd 含有甘露醇或乳糖之固形製劑
DK2123656T3 (da) * 2007-03-02 2014-09-08 Daiichi Sankyo Co Ltd Fremgangsmåde til fremstilling af prasugrelhydrochlorid med høg renhed
KR20150041173A (ko) 2007-04-27 2015-04-15 사이덱스 파마슈티칼스, 인크. 클로피도그렐 및 설포알킬 에테르 사이클로덱스트린을 함유하는 제형 및 사용 방법
CN101177430A (zh) * 2007-12-11 2008-05-14 鲁南制药集团股份有限公司 氢化吡啶衍生物及其盐的制备方法
US20090281136A1 (en) * 2008-05-08 2009-11-12 Sandeep Mhetre Prasugrel pharmaceutical formulations
KR20110045034A (ko) 2008-08-02 2011-05-03 루난 파마슈티컬 그룹 코퍼레이션 프라수그렐 황산수소염 및 이의 약제학적 조성물 및 용도
KR101991367B1 (ko) 2009-05-13 2019-06-21 사이덱스 파마슈티칼스, 인크. 프라수그렐 및 사이클로덱스트린 유도체를 포함하는 약학 조성물 및 그의 제조 및 사용 방법
CN102228691A (zh) * 2011-06-29 2011-11-02 北京阜康仁生物制药科技有限公司 阿司匹林和一种抗血小板药物的药物组合物
US9757395B2 (en) * 2012-12-20 2017-09-12 Otitopic Inc. Dry powder inhaler and methods of use
US9757529B2 (en) 2012-12-20 2017-09-12 Otitopic Inc. Dry powder inhaler and methods of use
EP2991634A1 (en) 2013-04-30 2016-03-09 Otitopic Inc. Dry powder formulations and methods of use
DK3107548T3 (da) 2014-02-20 2022-07-18 Otitopic Inc Tørpulverformuleringer til inhalation
WO2016122421A1 (en) 2015-01-29 2016-08-04 Pharmactive Ilaç Sanayi Ve Ticaret A.Ş. Stable pharmaceutical compositions containing prasugrel base

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2890240A (en) * 1956-03-28 1959-06-09 Monsanto Chemicals Aspirin crystallisation
US3235583A (en) * 1964-07-22 1966-02-15 Norwich Pharma Co Preparation of aspirin
US3890240A (en) * 1966-11-28 1975-06-17 Pitney Bowes Inc Toner compositions and methods for their preparation
FR2215948B1 (pt) 1973-02-01 1976-05-14 Centre Etd Ind Pharma
FR2345150A2 (fr) 1975-08-06 1977-10-21 Centre Etd Ind Pharma Nouveaux derives de la thienopyridine, et leur application
FR2307538A1 (fr) * 1975-04-18 1976-11-12 Centre Etd Ind Pharma Nouveau medicament anti-agregant plaquettaire
FR2312247A1 (fr) 1975-05-30 1976-12-24 Parcor Derives de la thieno-pyridine, leur procede de preparation et leurs applications
FR2358150A1 (fr) * 1976-07-13 1978-02-10 Parcor Nouvelles thieno (2,3-c) et (3,2-c) pyridines, leur procede de preparation et leur application
FR2376860A1 (fr) * 1977-01-07 1978-08-04 Parcor Tetrahydro-4,5,6,7 thieno (2,3-c) et (3,2-c) pyridines, leur procede de preparation et leur application therapeutique
GB1576511A (en) * 1977-03-29 1980-10-08 Parcor Thieno(2,3 - c) and (3,2 - c) pyridines process for their preparation and therapeutic applications thereof
GB2038625B (en) * 1978-12-29 1983-01-12 Parcor Therapeutic composition having an antithrombotic and antiblood-platelet-aggregating activity
CA1147658A (en) 1980-01-03 1983-06-07 Edouard Panak Therapeutic compositions having antithrombotic and anti-blood-platelet- aggregating activity
US4321266A (en) * 1980-10-06 1982-03-23 Sanofi 5-o-Cyanobenzyl-4,5,6,7-tetrahydrothieno [3,2-C] pyridine
US4400384A (en) * 1980-10-06 1983-08-23 Sanofi, S.A. 5-o-Cyanobenzyl-4,5,6,7-tetrahydrothieno [3,2-c] pyridine methanesulfonate and other novel salts thereof
FR2495156A1 (fr) * 1980-11-28 1982-06-04 Sanofi Sa Derives de la thieno-pyridinone, leur procede de preparation et leur application therapeutique
FR2528848A1 (fr) * 1982-06-16 1983-12-23 Sanofi Sa Nouveau derive de thieno-pyridone, son procede de preparation et son application therapeutique
FR2530247B1 (fr) * 1982-07-13 1986-05-16 Sanofi Sa Nouveaux derives de la thieno (3, 2-c) pyridine, leur procede de preparation et leur application therapeutique
FR2576901B1 (fr) * 1985-01-31 1987-03-20 Sanofi Sa Nouveaux derives de l'acide a-(oxo-2 hexahydro-2,4,5,6,7,7a thieno (3,2-c) pyridyl-5) phenyl acetique, leur procede de preparation et leur application therapeutique
FR2596392B1 (fr) 1986-03-27 1988-08-05 Sanofi Sa Derives de l'acide a-(hydroxy-3 oxo-2 hexahydro-2,4,5,6,7,7a thieno (3,2-c) pyridyl-5) phenylacetique, leur procede de preparation, leur application comme medicaments et les compositions les renfermant
FR2597102B1 (fr) 1986-04-14 1988-08-26 Sanofi Sa Derives de l'acide a-(hydroxy-7 tetrahydro-4,5,6,7 thieno (3,2-c) pyridyl-5) phenyl acetique, leur procede de preparation, leur application comme medicament et les compositions les renfermant
FR2652579B1 (fr) * 1989-10-02 1992-01-24 Sanofi Sa Derives d'hydroxy-2 thiophene et furanne condenses avec un cycle azote, sur procede de preparation et leur application en therapeutique.
US5401730A (en) * 1990-07-06 1995-03-28 The Hope Heart Institute Method for reducing platelet aggregation
FI101150B (fi) * 1991-09-09 1998-04-30 Sankyo Co Menetelmä lääkeaineina käyttökelpoisten tetrahydrotienopyridiinin johd annaisten valmistamiseksi
JP2712144B2 (ja) 1992-02-06 1998-02-10 田辺製薬株式会社 血小板凝集抑制組成物
EP0573975A1 (en) 1992-06-08 1993-12-15 Fuji Photo Film Co., Ltd. 2-alkoxycarbonyl-5-o-chlorobenzyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine derivative and process for producing the same
KR100196563B1 (ko) 1993-03-17 1999-06-15 기따사또 이찌로 혈소판 응집 저해작용을 갖는 신규한 화합물
JPH06271582A (ja) 1993-03-18 1994-09-27 Fuji Photo Film Co Ltd ４，５，６，７−テトラヒドロチエノ〔３，２−ｃ〕ピリジン誘導体の製造方法
JP3840662B2 (ja) * 1994-10-07 2006-11-01 宇部興産株式会社 ２−シリルオキシ−テトラヒドロチエノピリジン類、その塩およびその製造方法
JP3564791B2 (ja) 1995-04-21 2004-09-15 宇部興産株式会社 α−アミノケトン類の製造方法
FR2744918B1 (fr) * 1996-02-19 1998-05-07 Sanofi Sa Nouvelles associations de principes actifs contenant un derive de thieno(3,2-c)pyridine et un antithrombotique
ES2246575T3 (es) * 1998-06-17 2006-02-16 Bristol-Myers Squibb Company Prevencion del infarto cerebral mediante la administracion de una combinacion de un farmaco antiplaquetario bloqueador del receptor adp y un farmaco antihipertensivo.
US6509348B1 (en) * 1998-11-03 2003-01-21 Bristol-Myers Squibb Company Combination of an ADP-receptor blocking antiplatelet drug and a thromboxane A2 receptor antagonist and a method for inhibiting thrombus formation employing such combination
IT1306980B1 (it) 1999-01-13 2001-10-11 Magneti Marelli Spa Gruppo motore-cambio di velocita', in particolare per motocicli.
CN1108798C (zh) * 1999-01-26 2003-05-21 广东药学院 一种治疗、预防血栓形成及中风的复方制剂及其制备方法
JP2000266780A (ja) 1999-03-18 2000-09-29 Matsushita Electric Ind Co Ltd プローブカードとそれを用いた検査装置
IT1311924B1 (it) 1999-04-13 2002-03-20 Nicox Sa Composti farmaceutici.
IT1311923B1 (it) 1999-04-13 2002-03-20 Nicox Sa Composti farmaceutici.
FR2792836B3 (fr) 1999-04-30 2001-07-27 Sanofi Sa Composition pharmaceutique sous forme unitaire contenant de l'aspirine et de l'hydrogenosulfate de clopidogrel
MY125533A (en) * 1999-12-06 2006-08-30 Bristol Myers Squibb Co Heterocyclic dihydropyrimidine compounds
KR20090033917A (ko) 2000-07-06 2009-04-06 다이이찌 산쿄 가부시키가이샤 히드로피리딘 유도체 산부가염
JP4001199B2 (ja) 2000-07-06 2007-10-31 第一三共株式会社 ヒドロピリジン誘導体酸付加塩
HUP0400651A2 (hu) * 2000-11-07 2004-06-28 Bristol-Myers Squibb Company Szerin proteáz inhibitorokként alkalmazható savszármazékok és ezeket tartalmazó gyógyszerkészítmények
DE60135780D1 (de) 2000-12-25 2008-10-23 Daiichi Sankyo Co Ltd Aspirin enthaltende medizinische zusammensetzungen
US6670386B2 (en) * 2001-07-31 2003-12-30 Bristol-Myers Squibb Company Bicyclic modulators of androgen receptor function
DE10305984A1 (de) * 2003-02-13 2004-09-02 Helm Ag Salze organischer Säuren mit Clopidogrel und deren Verwendung zur Herstellung phamazeutischer Formulierungen
EP1704152A2 (en) * 2004-09-21 2006-09-27 Teva Pharmaceutical Industries Ltd Crystalline clopidogrel hydrobromide and processes for preparation thereof
DE112009000268T5 (de) * 2008-02-06 2011-06-01 Helm Ag Prasugrel-Salze mit verbesserten Eigenschaften
DE202008003557U1 (de) 2008-03-13 2008-06-05 Riela - Getreidetechnik Karl-Heinz Knoop E.K. Schubwendetrockner mit Feuchte-Messeinrichtung
DE602008002820D1 (de) 2008-04-25 2010-11-11 Sandoz Ag Hydrogensulfat von 2-Acetoxy-5-(a-cyclopropylcarbonyl-2-fluorbenzyl)-4,5,6,7-tetrahydrothienoÄ3,2-cÜpyridin und dessen Zubereitung
GB2469883A (en) 2009-04-30 2010-11-03 Sandoz Ag Novel crystalline form of Prasugrel hydrogensulphate
HU3745U (en) 2009-10-01 2010-03-29 Laszlo Borzan Disk guide device for target disk launcher or bowler equipments

Also Published As

Publication number Publication date
NZ526540A (en) 2004-11-26
HK1056118A1 (en) 2004-02-06
IL156456A0 (en) 2004-01-04
CA2432644C (en) 2013-07-23
EP1350511A1 (en) 2003-10-08
ES2311498T3 (es) 2009-02-16
CZ297570B6 (cs) 2007-02-07
HUP0400644A3 (en) 2009-06-29
US20070010499A1 (en) 2007-01-11
CZ20031660A3 (cs) 2003-12-17
KR100692934B1 (ko) 2007-03-12
US8569325B2 (en) 2013-10-29
DK1350511T3 (da) 2009-01-05
ZA200304878B (en) 2004-08-10
HUP0400644A2 (hu) 2004-06-28
ATE407675T1 (de) 2008-09-15
SK7542003A3 (en) 2003-12-02
WO2002051412A1 (fr) 2002-07-04
NO20032902D0 (no) 2003-06-24
US20040024013A1 (en) 2004-02-05
TWI293249B (en) 2008-02-11
EP1350511B1 (en) 2008-09-10
US8404703B2 (en) 2013-03-26
CY1108626T1 (el) 2014-04-09
NO20032902L (no) 2003-06-24
CN100341506C (zh) 2007-10-10
RU2262933C2 (ru) 2005-10-27
KR20030065558A (ko) 2003-08-06
IL156456A (en) 2006-12-10
CN1491109A (zh) 2004-04-21
MXPA03005770A (es) 2003-09-10
US20080108589A1 (en) 2008-05-08
EP1350511A4 (en) 2004-06-23
PL363183A1 (en) 2004-11-15
AU2002217464B2 (en) 2004-12-16
PL206138B1 (pl) 2010-07-30
DE60135780D1 (de) 2008-10-23
PT1350511E (pt) 2008-10-28
CA2432644A1 (en) 2002-07-04
SK287972B6 (sk) 2012-08-06

Similar Documents

Publication Publication Date Title
BR0116531A (pt) Composição farmacêutica, kit e uso de um composto
HRP20020880B1 (en) New pharmaceutical composition
BRPI0113331B8 (pt) derivados de fenilalanina ou seus sais parmaceuticamente aceitáveis, antagonista de integrina alfa 4, agente terapêutico ou agente preventivo para doenças inflamatórias, e, composição farmacêutica
CY1107554T1 (el) Αλατα προσθηκης οξεος παραγωγων υδροπυριδινης
AR037490A1 (es) Composiciones farmaceuticas solidas, proceso para su preparacion, kit para el tratamiento de la obesidad y uso de dichas composiciones en la elaboracion de medicamentos
ES2176684T3 (es) Nuevas asociaciones de principios activos que contienen clopidogrel y un antitrombotico.
BRPI0507653A (pt) derivados de imidazopiridina e imidazopiridina formulação farmacêutica compreendendo os mesmos e uso
EE200300033A (et) Tsüklopentanoindoolid, nende kasutamine ravimi valmistamiseks ning neid sisaldav farmatseutiline kompositsioon
AR014854A1 (es) POLIMORFO CRISTALINO DEL HIDROGENOSULFATO DE CLOPIDROGREL (FORMA2) (+)-(S)-ALFA-(2-CLOROFENIL)-4,5,6,7-TETRAHIDROTIENO[3,2-C]PIRIDINIL-5-ACETATO DE METILO ,PROCEDIMIENTO PARA SU PREPARACIoN Y COMPOSICIoN FARMACÉUTICA QUE LO CONTIENE
EE04799B1 (et) Ühendid, mis on kasulikud põletikuvastaste vahenditena, nende ühendite valmistamise meetodid ja neid sisaldavad farmatseutilised kompositsioonid
BR0014818A (pt) Imidazo-3-il-aminas bicìclicas procedimento de preparação e medicamentos que contém como substância ativa pelo menos uma imidazo-3-il-amina bicìclica
BR0112962B1 (pt) Composições farmacêuticas compreendendo ácido hialurônico, ácido glicirretínico e polivinilpirrolidona, e uso desses compostos na preparação de medicamentos
UY26258A1 (es) Derivados de 8-fenil-6,9-dihidro-[1,2,4] triazolo [3,4-i] purin-5-ona.
SV2005001979A (es) &#34;pirido[2,3-d]pirimidina-2,4-diaminas como inhibidores de pde 2 &#34; ref. pc25123a
HU0101333D0 (en) Diazepine derivatives and their salts, pharmaceutical compositions containing the same and activated blood coagulation factor x inhibitor composition
RU2003118638A (ru) Медицинские композиции, содержащие аспирин
BR0014826A (pt) Imidazo-3-il-aminas bicìclicas, procedimento de sua preparação e medicamentos que as contêm
PA8545001A1 (es) Sal citrato de 5,8,14-triazatetraciclo[10.3.1.0 2,11 .0 4,9] hexadeca-2(11),3,5,7,9-pentaeno y composiciones farmaceuticas de la mismas
HUP0201543A2 (en) Use of substituted imidazothiazoles as antidepressant agents, pharmaceutical compositions containing them and their preparation
BRPI0409818A (pt) compostos, composições farmacêuticas, método para o tratamento ou profilaxia de doenças, e, usos de compostos e de um ou mais compostos em combinação com outros compostos farmacologicamente ativos
BR0208566B1 (pt) Derivados de Beta-Carbolina, Seu Uso, e composição Farmacêutica
DE60137069D1 (de) Arzneizusammensetzungen enthaltend modafinilverbindungen
CR8678A (es) FORMAS POLIFORMICAS DE HIDROBROMURO ACETATO DE METIL (+)-(s)-ALFA-(-2-CLOROFENIL)-6,7-DIHIDROTIENO [3,2-C]PIRIDINA-5 (4H), HIDROBROMURO DE CLOPIDOGREL
AU1712700A (en) Restoration of platelet aggregation by antibody administration after gpiib/iiia antagonist treatment
ES2086195T3 (es) Nuevos derivados pseudopeptidicos de actividad antagonista de la bradiquinina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.

Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: UBE INDUSTRIES, LTD. (JP) , DAIICHI SANKYO COMPANY

Free format text: TRANSFERIDO POR INCORPORACAO DE: SANKYO COMPANY, LIMITED

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]

Free format text: DE ACORDO COM O ART.34 "II" DA LPI (LEI 9279, DE 14/05/96), O EXAME FICA SUSPENSO PARA QUE O REQUERENTE APRESENTE DOCUMENTOS NECESSARIOS A REGULARIZACAO DO PROCESSO E EXAME DO PEDIDO.

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) DA LPI

B12B Appeal against refusal [chapter 12.2 patent gazette]