HUP0400644A2 - Aszpirint tartalmazó gyógyászati kézítmények - Google Patents

Aszpirint tartalmazó gyógyászati kézítmények

Info

Publication number
HUP0400644A2
HUP0400644A2 HU0400644A HUP0400644A HUP0400644A2 HU P0400644 A2 HUP0400644 A2 HU P0400644A2 HU 0400644 A HU0400644 A HU 0400644A HU P0400644 A HUP0400644 A HU P0400644A HU P0400644 A2 HUP0400644 A2 HU P0400644A2
Authority
HU
Hungary
Prior art keywords
medicinal preparations
aspirin
pharmaceutical compositions
compositions containing
containing aspirin
Prior art date
Application number
HU0400644A
Other languages
English (en)
Inventor
Fumitoshi Asai
Teruhiko Inoue
Taketoshi Ogawa
Atsuhiro Sugidachi
Original Assignee
Sankyo Company Limited
Ube Industries, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=18858878&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0400644(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sankyo Company Limited, Ube Industries, Ltd. filed Critical Sankyo Company Limited
Publication of HUP0400644A2 publication Critical patent/HUP0400644A2/hu
Publication of HUP0400644A3 publication Critical patent/HUP0400644A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

A tatálmány aszpirint tartalmazó gyógyászati készítményekrevonatkozik. Közelebbről a találmány (I) képletű 2-acetoxi-5-(a-ciklopropilkarbonil-2-fluorobenzil)-4,5,6,7-tetrahidrotieno[3,2-c]piridint vagy ennek valamelyik gyógyászatilag elfogadható sóját ésaszpirint tartalmazó gyógyászati készítményekre vonatkozik. Mégközelebbről a találmány trombus vagy embólia által okozottmegbetegedések megelőzésére vagy kezelésére, különösen kezelésérealkalmas gyógyászati készítményekre vonatkozik, továbbá a gyógyászatikészítmények előállítására. A találmány szerinti gyógyászatikészítményekkel melegvérűek, különösen az ember kezelhető. Ó
HU0400644A 2000-12-25 2001-12-20 Pharmaceutical compositions containing aspirin HUP0400644A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000392983 2000-12-25
PCT/JP2001/011201 WO2002051412A1 (fr) 2000-12-25 2001-12-20 Compositions medicales contenant de l'aspirine

Publications (2)

Publication Number Publication Date
HUP0400644A2 true HUP0400644A2 (hu) 2004-06-28
HUP0400644A3 HUP0400644A3 (en) 2009-06-29

Family

ID=18858878

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0400644A HUP0400644A3 (en) 2000-12-25 2001-12-20 Pharmaceutical compositions containing aspirin

Country Status (26)

Country Link
US (3) US20040024013A1 (hu)
EP (1) EP1350511B1 (hu)
KR (1) KR100692934B1 (hu)
CN (1) CN100341506C (hu)
AT (1) ATE407675T1 (hu)
AU (1) AU2002217464B2 (hu)
BR (1) BR0116531A (hu)
CA (1) CA2432644C (hu)
CY (1) CY1108626T1 (hu)
CZ (1) CZ297570B6 (hu)
DE (1) DE60135780D1 (hu)
DK (1) DK1350511T3 (hu)
ES (1) ES2311498T3 (hu)
HK (1) HK1056118A1 (hu)
HU (1) HUP0400644A3 (hu)
IL (2) IL156456A0 (hu)
MX (1) MXPA03005770A (hu)
NO (1) NO20032902L (hu)
NZ (1) NZ526540A (hu)
PL (1) PL206138B1 (hu)
PT (1) PT1350511E (hu)
RU (1) RU2262933C2 (hu)
SK (1) SK287972B6 (hu)
TW (1) TWI293249B (hu)
WO (1) WO2002051412A1 (hu)
ZA (1) ZA200304878B (hu)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001267916B2 (en) * 2000-07-06 2004-09-09 Daiichi Sankyo Company, Limited Hydropyridine derivative acid addition salts
CZ297570B6 (cs) 2000-12-25 2007-02-07 Sankyo Company, Limited Farmaceutický prípravek obsahující 2-acetoxypyridinový derivát a aspirin, které spolu pusobí v synergickém úcinku, kit jej obsahující a pouzití
WO2004098713A2 (en) * 2003-05-05 2004-11-18 Eli Lilly And Company Treating cardiovascular diseases with a compound of formula (i) (cs 747 - prasugrel; rn 150322-43-4)
CN100488163C (zh) * 2005-01-19 2009-05-13 华为技术有限公司 组播业务处理方法和系统
BRPI0612624A2 (pt) * 2005-06-17 2016-11-29 Lilly Co Eli métodos para tratar doença vascular em um humano, e para prevenção e/ou tratamento de uma doença induzida por trombose ou uma doença induzida por tromboembolismo em um humano, e, uso de um composto
DE102005029612A1 (de) * 2005-06-23 2007-01-04 Hochschule Bremen Vorrichtung zum Erzeugen eines Panoramabildes
EP1940399A2 (en) * 2005-08-19 2008-07-09 Eli Lilly & Company Use of par-i/par- 4 inhibitors for treating or preventing vascular diseases
EP2032521B1 (en) * 2006-06-27 2009-10-28 Sandoz AG New method for salt preparation
BRPI0719393B8 (pt) * 2006-12-07 2021-05-25 Daiichi Sankyo Co Ltd composição farmacêutica
CA2672154C (en) * 2006-12-07 2014-11-18 Daiichi Sankyo Company, Limited Pharmaceutical composition having improved storage stability
WO2008072534A1 (ja) * 2006-12-07 2008-06-19 Daiichi Sankyo Company, Limited マンニトール又は乳糖を含有する固形製剤
US20110201814A1 (en) * 2006-12-07 2011-08-18 Daiichi Sankyo Company Limited Method for producing solid preparation
KR101665705B1 (ko) * 2006-12-07 2016-10-12 다이이찌 산쿄 가부시키가이샤 안정성이 개선된 필름 코팅 제제
MY151726A (en) * 2007-03-02 2014-06-30 Daiichi Sankyo Co Ltd Process for production of prasugrel hydrochloride having high purity
MX2009011619A (es) 2007-04-27 2010-01-18 Cydex Pharmaceuticals Inc Formulaciones que contienen clopidogrel y eter sulfoalquilico-ciclodextrina y metodos de uso.
CN101177430A (zh) * 2007-12-11 2008-05-14 鲁南制药集团股份有限公司 氢化吡啶衍生物及其盐的制备方法
WO2010015144A1 (zh) 2008-08-02 2010-02-11 鲁南制药集团股份有限公司 普拉格雷硫酸氢盐及其药物组合物和应用
US20090281136A1 (en) * 2008-05-08 2009-11-12 Sandeep Mhetre Prasugrel pharmaceutical formulations
WO2010132711A1 (en) 2009-05-13 2010-11-18 Cydex Pharmaceuticals, Inc. Pharmaceutical compositions comprising prasugrel and cyclodextrin derivatives and methods of making and using the same
CN102228691A (zh) * 2011-06-29 2011-11-02 北京阜康仁生物制药科技有限公司 阿司匹林和一种抗血小板药物的药物组合物
US9757529B2 (en) 2012-12-20 2017-09-12 Otitopic Inc. Dry powder inhaler and methods of use
US9757395B2 (en) * 2012-12-20 2017-09-12 Otitopic Inc. Dry powder inhaler and methods of use
WO2014178891A1 (en) 2013-04-30 2014-11-06 Otitopic Inc. Dry powder formulations and methods of use
EP3107548B8 (en) 2014-02-20 2022-07-20 Otitopic Inc. Dry powder formulations for inhalation
WO2016122421A1 (en) 2015-01-29 2016-08-04 Pharmactive Ilaç Sanayi Ve Ticaret A.Ş. Stable pharmaceutical compositions containing prasugrel base

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2890240A (en) * 1956-03-28 1959-06-09 Monsanto Chemicals Aspirin crystallisation
US3235583A (en) * 1964-07-22 1966-02-15 Norwich Pharma Co Preparation of aspirin
US3890240A (en) * 1966-11-28 1975-06-17 Pitney Bowes Inc Toner compositions and methods for their preparation
FR2345150A2 (fr) 1975-08-06 1977-10-21 Centre Etd Ind Pharma Nouveaux derives de la thienopyridine, et leur application
FR2215948B1 (hu) 1973-02-01 1976-05-14 Centre Etd Ind Pharma
FR2307538A1 (fr) * 1975-04-18 1976-11-12 Centre Etd Ind Pharma Nouveau medicament anti-agregant plaquettaire
FR2312247A1 (fr) 1975-05-30 1976-12-24 Parcor Derives de la thieno-pyridine, leur procede de preparation et leurs applications
FR2358150A1 (fr) * 1976-07-13 1978-02-10 Parcor Nouvelles thieno (2,3-c) et (3,2-c) pyridines, leur procede de preparation et leur application
FR2376860A1 (fr) * 1977-01-07 1978-08-04 Parcor Tetrahydro-4,5,6,7 thieno (2,3-c) et (3,2-c) pyridines, leur procede de preparation et leur application therapeutique
GB1576511A (en) * 1977-03-29 1980-10-08 Parcor Thieno(2,3 - c) and (3,2 - c) pyridines process for their preparation and therapeutic applications thereof
GB2038625B (en) * 1978-12-29 1983-01-12 Parcor Therapeutic composition having an antithrombotic and antiblood-platelet-aggregating activity
CA1147658A (en) 1980-01-03 1983-06-07 Edouard Panak Therapeutic compositions having antithrombotic and anti-blood-platelet- aggregating activity
US4400384A (en) * 1980-10-06 1983-08-23 Sanofi, S.A. 5-o-Cyanobenzyl-4,5,6,7-tetrahydrothieno [3,2-c] pyridine methanesulfonate and other novel salts thereof
US4321266A (en) * 1980-10-06 1982-03-23 Sanofi 5-o-Cyanobenzyl-4,5,6,7-tetrahydrothieno [3,2-C] pyridine
FR2495156A1 (fr) * 1980-11-28 1982-06-04 Sanofi Sa Derives de la thieno-pyridinone, leur procede de preparation et leur application therapeutique
FR2528848A1 (fr) * 1982-06-16 1983-12-23 Sanofi Sa Nouveau derive de thieno-pyridone, son procede de preparation et son application therapeutique
FR2530247B1 (fr) * 1982-07-13 1986-05-16 Sanofi Sa Nouveaux derives de la thieno (3, 2-c) pyridine, leur procede de preparation et leur application therapeutique
FR2576901B1 (fr) * 1985-01-31 1987-03-20 Sanofi Sa Nouveaux derives de l'acide a-(oxo-2 hexahydro-2,4,5,6,7,7a thieno (3,2-c) pyridyl-5) phenyl acetique, leur procede de preparation et leur application therapeutique
FR2596392B1 (fr) 1986-03-27 1988-08-05 Sanofi Sa Derives de l'acide a-(hydroxy-3 oxo-2 hexahydro-2,4,5,6,7,7a thieno (3,2-c) pyridyl-5) phenylacetique, leur procede de preparation, leur application comme medicaments et les compositions les renfermant
FR2597102B1 (fr) 1986-04-14 1988-08-26 Sanofi Sa Derives de l'acide a-(hydroxy-7 tetrahydro-4,5,6,7 thieno (3,2-c) pyridyl-5) phenyl acetique, leur procede de preparation, leur application comme medicament et les compositions les renfermant
FR2652579B1 (fr) * 1989-10-02 1992-01-24 Sanofi Sa Derives d'hydroxy-2 thiophene et furanne condenses avec un cycle azote, sur procede de preparation et leur application en therapeutique.
US5401730A (en) * 1990-07-06 1995-03-28 The Hope Heart Institute Method for reducing platelet aggregation
FI101150B (fi) * 1991-09-09 1998-04-30 Sankyo Co Menetelmä lääkeaineina käyttökelpoisten tetrahydrotienopyridiinin johd annaisten valmistamiseksi
CA2087743C (en) 1992-02-06 1999-04-27 Akio Odawara Pharmaceutical composition for inhibiting platelet aggregation
EP0573975A1 (en) 1992-06-08 1993-12-15 Fuji Photo Film Co., Ltd. 2-alkoxycarbonyl-5-o-chlorobenzyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine derivative and process for producing the same
WO1994021599A1 (en) 1993-03-17 1994-09-29 Meiji Seika Kabushiki Kaisha Novel compound with platelet aggregation inhibitor activity
JPH06271582A (ja) 1993-03-18 1994-09-27 Fuji Photo Film Co Ltd ４，５，６，７−テトラヒドロチエノ〔３，２−ｃ〕ピリジン誘導体の製造方法
DE69526443T2 (de) * 1994-10-07 2002-12-12 Ube Industries 2-silyloxy-tetrahydrothienopyridin, sein salz und verfahren zu seiner herstellung
JP3564791B2 (ja) 1995-04-21 2004-09-15 宇部興産株式会社 α−アミノケトン類の製造方法
FR2744918B1 (fr) * 1996-02-19 1998-05-07 Sanofi Sa Nouvelles associations de principes actifs contenant un derive de thieno(3,2-c)pyridine et un antithrombotique
WO1999065500A1 (en) * 1998-06-17 1999-12-23 Bristol-Myers Squibb Company Preventing cerebral infarction through administration of adp-receptor antiplatelet and antihypertensive drugs in combination
US6509348B1 (en) * 1998-11-03 2003-01-21 Bristol-Myers Squibb Company Combination of an ADP-receptor blocking antiplatelet drug and a thromboxane A2 receptor antagonist and a method for inhibiting thrombus formation employing such combination
IT1306980B1 (it) 1999-01-13 2001-10-11 Magneti Marelli Spa Gruppo motore-cambio di velocita', in particolare per motocicli.
CN1108798C (zh) * 1999-01-26 2003-05-21 广东药学院 一种治疗、预防血栓形成及中风的复方制剂及其制备方法
JP2000266780A (ja) 1999-03-18 2000-09-29 Matsushita Electric Ind Co Ltd プローブカードとそれを用いた検査装置
IT1311924B1 (it) 1999-04-13 2002-03-20 Nicox Sa Composti farmaceutici.
IT1311923B1 (it) 1999-04-13 2002-03-20 Nicox Sa Composti farmaceutici.
FR2792836B3 (fr) 1999-04-30 2001-07-27 Sanofi Sa Composition pharmaceutique sous forme unitaire contenant de l'aspirine et de l'hydrogenosulfate de clopidogrel
MY125533A (en) * 1999-12-06 2006-08-30 Bristol Myers Squibb Co Heterocyclic dihydropyrimidine compounds
JP4001199B2 (ja) 2000-07-06 2007-10-31 第一三共株式会社 ヒドロピリジン誘導体酸付加塩
AU2001267916B2 (en) 2000-07-06 2004-09-09 Daiichi Sankyo Company, Limited Hydropyridine derivative acid addition salts
EP1332131A2 (en) * 2000-11-07 2003-08-06 Bristol-Myers Squibb Company Acid derivatives useful as serine protease inhibitors
CZ297570B6 (cs) 2000-12-25 2007-02-07 Sankyo Company, Limited Farmaceutický prípravek obsahující 2-acetoxypyridinový derivát a aspirin, které spolu pusobí v synergickém úcinku, kit jej obsahující a pouzití
US6670386B2 (en) * 2001-07-31 2003-12-30 Bristol-Myers Squibb Company Bicyclic modulators of androgen receptor function
DE10305984A1 (de) * 2003-02-13 2004-09-02 Helm Ag Salze organischer Säuren mit Clopidogrel und deren Verwendung zur Herstellung phamazeutischer Formulierungen
US20060154957A1 (en) * 2004-09-21 2006-07-13 Nina Finkelstein Crystalline clopidogrel hydrobromide and processes for preparation thereof
EP2257556A1 (en) * 2008-02-06 2010-12-08 Helm AG Prasugrel salts with improved properties
DE202008003557U1 (de) 2008-03-13 2008-06-05 Riela - Getreidetechnik Karl-Heinz Knoop E.K. Schubwendetrockner mit Feuchte-Messeinrichtung
ATE482961T1 (de) 2008-04-25 2010-10-15 Sandoz Ag Hydrogensulfat von 2-acetoxy-5-(a- cyclopropylcarbonyl-2-fluorbenzyl)-4,5,6,7- tetrahydrothienoä3,2-cüpyridin und dessen zubereitung
GB2469883A (en) 2009-04-30 2010-11-03 Sandoz Ag Novel crystalline form of Prasugrel hydrogensulphate
HU3745U (en) 2009-10-01 2010-03-29 Laszlo Borzan Disk guide device for target disk launcher or bowler equipments

Also Published As

Publication number Publication date
EP1350511A1 (en) 2003-10-08
US8404703B2 (en) 2013-03-26
SK7542003A3 (en) 2003-12-02
IL156456A0 (en) 2004-01-04
CN100341506C (zh) 2007-10-10
US20070010499A1 (en) 2007-01-11
SK287972B6 (sk) 2012-08-06
EP1350511B1 (en) 2008-09-10
CZ297570B6 (cs) 2007-02-07
TWI293249B (en) 2008-02-11
NO20032902D0 (no) 2003-06-24
DE60135780D1 (de) 2008-10-23
DK1350511T3 (da) 2009-01-05
NO20032902L (no) 2003-06-24
EP1350511A4 (en) 2004-06-23
MXPA03005770A (es) 2003-09-10
AU2002217464B2 (en) 2004-12-16
CN1491109A (zh) 2004-04-21
PL206138B1 (pl) 2010-07-30
CA2432644A1 (en) 2002-07-04
ES2311498T3 (es) 2009-02-16
ZA200304878B (en) 2004-08-10
HUP0400644A3 (en) 2009-06-29
KR100692934B1 (ko) 2007-03-12
HK1056118A1 (en) 2004-02-06
US8569325B2 (en) 2013-10-29
CA2432644C (en) 2013-07-23
KR20030065558A (ko) 2003-08-06
IL156456A (en) 2006-12-10
US20080108589A1 (en) 2008-05-08
RU2262933C2 (ru) 2005-10-27
NZ526540A (en) 2004-11-26
CY1108626T1 (el) 2014-04-09
ATE407675T1 (de) 2008-09-15
PT1350511E (pt) 2008-10-28
CZ20031660A3 (cs) 2003-12-17
US20040024013A1 (en) 2004-02-05
PL363183A1 (en) 2004-11-15
BR0116531A (pt) 2004-02-25
WO2002051412A1 (fr) 2002-07-04

Similar Documents

Publication Publication Date Title
HUP0400644A2 (hu) Aszpirint tartalmazó gyógyászati kézítmények
MY128654A (en) Liquid pharmaceutical composition containing an erythropoietin derivative
SE9702001D0 (sv) Novel compounds
GEP20053511B (en) ) β-Carboline Derivatives Useful as Inhibitors of Phosphodiesterase
EA200600064A1 (ru) Производные тиенопиридона как ингибиторы киназ
EA200200306A1 (ru) Трициклические ингибиторы поли(адф-рибозо)полимераз
MXPA04004966A (es) Nucleosidos de 3-beta-d-ribofuranoziltiazol(4,5-d(pirimidina y uso de los mismos.
WO2001035950A3 (en) Benzamide therapeutics and methods for treating inflammatory bowel disease
NO20063768L (no) 1H-tieno[2,3c] pyrazolderivater anvendelige som kinaseinhibitorer
AR034343A1 (es) Combinaciones farmaceuticas
AP1564A (en) Piperazinyl sulfonic acid derivatives, their pharmaceutical compositions and methods of use.
NO20016201L (no) Tienopyrimidiner som fosfodiesteraseinhibitorer
WO2001057042A3 (de) 4-pyridyl- und 2,4-pyrimidinyl-substituierte pyrrolderivate und ihre anwendung in der pharmazie
ATE381568T1 (de) Pyrano(2,3-c)imidazo(1,2-a)pyridin-derivate zur behandlung von gastrointestinalen erkrankungen
HUP9901247A3 (en) Use of naphthimidazole-, naphthoxazole- and naphthothiazole-diones for the preparation of pharmaceutical compositions treating diseases caused by vascular function deficiency
IS6437A (is) Ný setin pýrazóló [4,3-e]díazepín lyfjasamsetningar sem innihalda þau, notkun sem læknandi afurðir og aðferðir við framleiðslu þeirra
DE60130253D1 (de) Zusammensetzungen zur verhinderung der adhäsion
AU2001255168A1 (en) Compositions and methods for the treatment of immune related diseases
NO20022739D0 (no) Nye terapeutiske kombinasjoner av (S)-2-(benzylamino-metyl)- 2,3,8,9-tetrahydro-7H-1,4-dioksino[2,3-e]indol-8-on ognevroleptika for behandling eller forhindring av psykotiskelidelser
GEP20043356B (en) Compounds Useful For Treatment or Prevention of Diseases Mediated By Alpha- 2B-Adrenoceptor
DE50212538D1 (de) Substituierte 5,6,6a,11b-tetrahydro-7-oxa-5-aza-benzoäcüfluoren-6-carbonsäurederivate als nmda-antagonisten
WO2001092331A8 (en) Compositions and methods for the treatment of immune related diseases

Legal Events

Date Code Title Description
GB9A Succession in title

Owner name: DAIICHI SANKYO COMPANY, LIMITED, JP

Free format text: FORMER OWNER(S): SANKYO COMPANY LIMITED, JP

Owner name: UBE INDUSTRIES, LTD., JP

Free format text: FORMER OWNER(S): SANKYO COMPANY LIMITED, JP

FC4A Lapse of provisional application due to refusal