BR0014826A - Imidazo-3-il-aminas bicìclicas, procedimento de sua preparação e medicamentos que as contêm - Google Patents

Imidazo-3-il-aminas bicìclicas, procedimento de sua preparação e medicamentos que as contêm

Info

Publication number
BR0014826A
BR0014826A BR0014826-1A BR0014826A BR0014826A BR 0014826 A BR0014826 A BR 0014826A BR 0014826 A BR0014826 A BR 0014826A BR 0014826 A BR0014826 A BR 0014826A
Authority
BR
Brazil
Prior art keywords
amines
preparation procedure
bicyclic imidazo
bicyclic
medications containing
Prior art date
Application number
BR0014826-1A
Other languages
English (en)
Inventor
Mathias Gerlach
Corinna Maul
Original Assignee
Gr Nenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE1999148437 external-priority patent/DE19948437A1/de
Priority claimed from DE19948434A external-priority patent/DE19948434A1/de
Application filed by Gr Nenthal Gmbh filed Critical Gr Nenthal Gmbh
Publication of BR0014826A publication Critical patent/BR0014826A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Imidazo-3-il-aminas bicíclicas, procedimento de sua preparação e medicamentos que as contêm ditas Imidazo-3-il-aminas bicíclicas de fórmula geral I: na forma de suas bases ou sais farmaceuticamente aceitáveis, procedimento de sua preparação e medicamento que contém como substância ativa pelo menos uma amidazo-3-il-amina bicíclica da fórmula geral I na sua forma de base ou sal farmaceuticamente aceitável.
BR0014826-1A 1999-10-08 2000-09-18 Imidazo-3-il-aminas bicìclicas, procedimento de sua preparação e medicamentos que as contêm BR0014826A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE1999148437 DE19948437A1 (de) 1999-10-08 1999-10-08 Am Sechsring substituierte, bicyclische Imidazo-3-aminderivate
DE19948434A DE19948434A1 (de) 1999-10-08 1999-10-08 Substanzbibliothek enthaltend bicyclische Imidazo-5-amine und/oder bicyclische Imidazo-3-amine
PCT/EP2000/009095 WO2001027110A2 (de) 1999-10-08 2000-09-18 Am sechsring substituierte, bicyclische imidazo-3-yl-aminderivate

Publications (1)

Publication Number Publication Date
BR0014826A true BR0014826A (pt) 2002-08-27

Family

ID=26055217

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0014826-1A BR0014826A (pt) 1999-10-08 2000-09-18 Imidazo-3-il-aminas bicìclicas, procedimento de sua preparação e medicamentos que as contêm

Country Status (27)

Country Link
US (1) US6849642B2 (pt)
EP (1) EP1218380B1 (pt)
JP (1) JP2003517466A (pt)
KR (1) KR20020038804A (pt)
CN (1) CN1222525C (pt)
AR (1) AR025961A1 (pt)
AT (1) ATE256684T1 (pt)
AU (1) AU780823B2 (pt)
BR (1) BR0014826A (pt)
CA (1) CA2386813C (pt)
CO (1) CO5210870A1 (pt)
CZ (1) CZ300315B6 (pt)
DE (1) DE50004817D1 (pt)
DK (1) DK1218380T3 (pt)
ES (1) ES2213044T3 (pt)
HK (1) HK1047748B (pt)
HU (1) HUP0203739A3 (pt)
IL (2) IL148998A0 (pt)
MX (1) MXPA02003547A (pt)
NO (1) NO20021563L (pt)
NZ (1) NZ518637A (pt)
PE (1) PE20010631A1 (pt)
PT (1) PT1218380E (pt)
RU (1) RU2002110282A (pt)
SK (1) SK286450B6 (pt)
UY (1) UY26371A1 (pt)
WO (1) WO2001027110A2 (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10043845A1 (de) * 2000-09-06 2002-03-14 Gruenenthal Gmbh Verfahren zur Messung der Aktivität der NO-Synthase
WO2002048146A2 (de) * 2000-12-13 2002-06-20 Basf Aktiengesellschaft Verwendung von substituierten imidazoazinen, neue imidazoazine, verfahren zu deren herstellung, sowie sie enthaltende mittel
US7186832B2 (en) 2003-02-20 2007-03-06 Sugen Inc. Use of 8-amino-aryl-substituted imidazopyrazines as kinase inhibitors
US7157460B2 (en) 2003-02-20 2007-01-02 Sugen Inc. Use of 8-amino-aryl-substituted imidazopyrazines as kinase inhibitors
DE102004021716A1 (de) * 2004-04-30 2005-12-01 Grünenthal GmbH Substituierte Imidazo[1,2-a]pyridin-Verbindungen und Arzneimittel enthaltend substituierte Imidazo[1,2-a]pyridin-Verbindungen
DE102004044884A1 (de) * 2004-09-14 2006-05-24 Grünenthal GmbH Substituierte bizyklische Imidazo-3-yl-amin-Verbindungen
DE102005016547A1 (de) * 2005-04-08 2006-10-12 Grünenthal GmbH Substituierte 5,6,7,8-Tetrahydro-imidazo(1,2-a)pyridin-2-ylamin-Verbindungen und deren Verwendung zur Herstellung von Arzneimitteln
CA2620223A1 (en) 2005-09-02 2007-03-08 Abbott Laboratories Novel imidazo based heterocycles
EA200870592A1 (ru) * 2006-05-31 2009-08-28 Галапагос Н.В. Триазолопиразиновые соединения, пригодные для лечения дегенеративных и воспалительных заболеваний
WO2008134553A1 (en) * 2007-04-26 2008-11-06 Xenon Pharmaceuticals Inc. Methods of using bicyclic compounds in treating sodium channel-mediated diseases
CN101801966A (zh) * 2007-07-18 2010-08-11 诺瓦提斯公司 双环杂芳基化合物和它们作为激酶抑制剂的用途
ES2552733T3 (es) 2007-11-16 2015-12-01 Rigel Pharmaceuticals, Inc. Compuestos de carboxamida, sulfonamida y amina para trastornos metabólicos
JP5650540B2 (ja) 2007-12-12 2015-01-07 ライジェル ファーマシューティカルズ， インコーポレイテッド 代謝障害のためのカルボキサミド、スルホンアミド、およびアミン化合物
PT2266990E (pt) * 2008-04-15 2012-12-27 Eisai R&D Man Co Ltd Composto de 3-fenilpirazolo[5,1-b]tiazole
US8314107B2 (en) 2008-04-23 2012-11-20 Rigel Pharmaceuticals, Inc. Carboxamide compounds and methods for using the same
WO2010032195A1 (en) 2008-09-16 2010-03-25 Csir Imidazopyridines and imidazopyrimidines as hiv-i reverse transcriptase inhibitors
AU2010233352B2 (en) * 2009-04-07 2014-06-26 The University Of The Witwatersrand, Johannesburg Imidazo[1,2-A] pyridine-6-carboxamide derivatives, their use for the treatment of colon cancer and their method of manufacture
AR078521A1 (es) * 2009-10-08 2011-11-16 Eisai R&D Man Co Ltd Compuesto pirazolotiazol
SG184073A1 (en) * 2010-03-18 2012-10-30 Pasteur Institut Korea Anti-infective compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3489755A (en) 1966-08-03 1970-01-13 Pfizer & Co C Imidazo (1,2-b) pyridazines
EP0068378B1 (en) 1981-06-26 1986-03-05 Schering Corporation Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
NZ221996A (en) * 1986-10-07 1989-08-29 Yamanouchi Pharma Co Ltd Imidazo-pyridine derivatives and pharmaceutical compositions
TW274551B (pt) * 1991-04-16 1996-04-21 Takeda Pharm Industry Co Ltd
KR19990007836A (ko) * 1995-04-21 1999-01-25 다나까 테츠오 융합된 이미다조[1, 2-a]피리딘

Also Published As

Publication number Publication date
HUP0203739A3 (en) 2004-07-28
EP1218380B1 (de) 2003-12-17
MXPA02003547A (es) 2002-09-18
HUP0203739A2 (hu) 2003-02-28
CA2386813A1 (en) 2001-04-19
WO2001027110A3 (de) 2001-09-20
NO20021563L (no) 2002-06-04
AR025961A1 (es) 2002-12-26
CN1222525C (zh) 2005-10-12
ES2213044T3 (es) 2004-08-16
NZ518637A (en) 2004-12-24
HK1047748A1 (en) 2003-03-07
AU780823B2 (en) 2005-04-21
IL148998A0 (en) 2002-11-10
WO2001027110A2 (de) 2001-04-19
RU2002110282A (ru) 2003-12-20
CO5210870A1 (es) 2002-10-30
PT1218380E (pt) 2004-05-31
KR20020038804A (ko) 2002-05-23
CN1402727A (zh) 2003-03-12
CZ20021243A3 (cs) 2003-12-17
JP2003517466A (ja) 2003-05-27
AU7519900A (en) 2001-04-23
CA2386813C (en) 2008-09-02
US20020183327A1 (en) 2002-12-05
SK4612002A3 (en) 2002-09-10
IL148998A (en) 2006-12-31
PE20010631A1 (es) 2001-07-07
CZ300315B6 (cs) 2009-04-15
UY26371A1 (es) 2000-10-31
PL364866A1 (en) 2004-12-27
US6849642B2 (en) 2005-02-01
SK286450B6 (sk) 2008-10-07
EP1218380A2 (de) 2002-07-03
HK1047748B (zh) 2004-10-21
DK1218380T3 (da) 2004-03-15
NO20021563D0 (no) 2002-04-03
ATE256684T1 (de) 2004-01-15
DE50004817D1 (de) 2004-01-29

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A, 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1929 DE 26/12/2007.