BR0014818A - Imidazo-3-il-aminas bicìclicas procedimento de preparação e medicamentos que contém como substância ativa pelo menos uma imidazo-3-il-amina bicìclica - Google Patents

Imidazo-3-il-aminas bicìclicas procedimento de preparação e medicamentos que contém como substância ativa pelo menos uma imidazo-3-il-amina bicìclica

Info

Publication number
BR0014818A
BR0014818A BR0014818-0A BR0014818A BR0014818A BR 0014818 A BR0014818 A BR 0014818A BR 0014818 A BR0014818 A BR 0014818A BR 0014818 A BR0014818 A BR 0014818A
Authority
BR
Brazil
Prior art keywords
amines
imidazo
bicyclic imidazo
bicyclic
drugs containing
Prior art date
Application number
BR0014818-0A
Other languages
English (en)
Inventor
Mathias Gerlach
Corinna Maul
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19948434A external-priority patent/DE19948434A1/de
Priority claimed from DE1999148438 external-priority patent/DE19948438B4/de
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of BR0014818A publication Critical patent/BR0014818A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures

Abstract

"IMIDAZO-3-IL-AMINAS BICìCLICAS PROCEDIMENTO DE PREPARAçãO E MEDICAMENTOS QUE CONTêM COMO SUBSTâNCIA ATIVA PELO MENOS UMA IMIDAZO-3-IL-AMINA BICìCLICA". Onde uma Imidazo-3-il-aminas bicíclicas da fórmula geral I sob a forma de suas bases ou seus sais farmaceuticamente toleráveis, procedimento para sua preparação e medicamentos que contêm como substância ativa pelo menos uma imidazo-3-il-amina bicíclica da fórmula geral I sob a forma de sua base ou um sal farmaceuticamente tolerável.
BR0014818-0A 1999-10-08 2000-09-18 Imidazo-3-il-aminas bicìclicas procedimento de preparação e medicamentos que contém como substância ativa pelo menos uma imidazo-3-il-amina bicìclica BR0014818A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19948434A DE19948434A1 (de) 1999-10-08 1999-10-08 Substanzbibliothek enthaltend bicyclische Imidazo-5-amine und/oder bicyclische Imidazo-3-amine
DE1999148438 DE19948438B4 (de) 1999-10-08 1999-10-08 Bicyclische Imidazo-3-aminderivate
PCT/EP2000/009096 WO2001027111A2 (de) 1999-10-08 2000-09-18 Bicyclische imidazo-3-yl-aminderivate

Publications (1)

Publication Number Publication Date
BR0014818A true BR0014818A (pt) 2002-06-18

Family

ID=26055218

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0014818-0A BR0014818A (pt) 1999-10-08 2000-09-18 Imidazo-3-il-aminas bicìclicas procedimento de preparação e medicamentos que contém como substância ativa pelo menos uma imidazo-3-il-amina bicìclica

Country Status (26)

Country Link
US (1) US6638933B2 (pt)
EP (1) EP1218382B1 (pt)
JP (1) JP2003511451A (pt)
KR (1) KR100756592B1 (pt)
CN (1) CN1257169C (pt)
AR (1) AR025962A1 (pt)
AT (1) ATE258554T1 (pt)
AU (1) AU779197B2 (pt)
BR (1) BR0014818A (pt)
CA (1) CA2382919C (pt)
CO (1) CO5251378A1 (pt)
CZ (1) CZ20021210A3 (pt)
DE (1) DE50005155D1 (pt)
DK (1) DK1218382T3 (pt)
ES (1) ES2213611T3 (pt)
HK (1) HK1047747B (pt)
HU (1) HUP0203052A3 (pt)
NO (1) NO322754B1 (pt)
NZ (2) NZ518390A (pt)
PE (1) PE20010634A1 (pt)
PL (1) PL355206A1 (pt)
PT (1) PT1218382E (pt)
RU (1) RU2264402C2 (pt)
SK (1) SK286788B6 (pt)
UY (1) UY26372A1 (pt)
WO (1) WO2001027111A2 (pt)

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US20040077605A1 (en) * 2001-06-20 2004-04-22 Salvati Mark E. Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
DE10043845A1 (de) * 2000-09-06 2002-03-14 Gruenenthal Gmbh Verfahren zur Messung der Aktivität der NO-Synthase
EP1854798A3 (en) 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
EP1343785A2 (de) * 2000-12-13 2003-09-17 Basf Aktiengesellschaft Verwendung von substituierten imidazoazinen, neue imidazoazine, verfahren zu deren herstellung, sowie sie enthaltende mittel
US20040087548A1 (en) 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
DE102004021716A1 (de) * 2004-04-30 2005-12-01 Grünenthal GmbH Substituierte Imidazo[1,2-a]pyridin-Verbindungen und Arzneimittel enthaltend substituierte Imidazo[1,2-a]pyridin-Verbindungen
EP1765351B9 (en) * 2004-06-09 2010-03-24 Oncalis AG Protein kinase inhibitors
US7923041B2 (en) * 2005-02-03 2011-04-12 Signum Biosciences, Inc. Compositions and methods for enhancing cognitive function
CA2602444C (en) * 2005-03-23 2013-03-19 F.Hoffmann-La Roche Ag Acetylenyl-pyrazolo-pyrimidine derivatives as mglur2 antagonists
CN101263142A (zh) * 2005-05-20 2008-09-10 阿雷生物药品公司 Raf抑制剂化合物及其使用方法
EP1901748B1 (en) * 2005-06-09 2010-09-08 Oncalis AG Angiogenesis inhibitors
WO2007028051A2 (en) 2005-09-02 2007-03-08 Abbott Laboratories Novel imidazo based heterocycles
EP1845098A1 (en) * 2006-03-29 2007-10-17 Ferrer Internacional, S.A. Imidazo[1,2-b]pyridazines, their processes of preparation and their use as GABA receptor ligands
BRPI0712531A2 (pt) * 2006-05-31 2012-12-25 Galapagos Nv composto de triazolopirazina éteis para o tratamento de doenÇas degenarativas e inflamatàrias
US20100173930A1 (en) * 2006-08-01 2010-07-08 Alex Muci Certain Chemical Entities, Compositions and Methods
US8227603B2 (en) * 2006-08-01 2012-07-24 Cytokinetics, Inc. Modulating skeletal muscle
US8299248B2 (en) * 2006-08-02 2012-10-30 Cytokinetics, Incorporated Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols and methods for their use
PL2583970T3 (pl) * 2006-08-02 2016-05-31 Cytokinetics Inc Określone cząstki chemiczne, kompozycje i sposoby zawierające imidazopirymidyny
EP1974729A1 (en) * 2007-03-28 2008-10-01 Santhera Pharmaceuticals (Schweiz) AG Substituted imidazopyridine derivates as melanocortin- 4 receptor antagonists
US7851484B2 (en) * 2007-03-30 2010-12-14 Cytokinetics, Inc. Certain chemical entities, compositions, and methods
GB0708188D0 (en) * 2007-04-27 2007-06-06 Merck Sharp & Dohme Therapeutic compounds
JP4654325B2 (ja) * 2008-04-15 2011-03-16 エーザイ・アール・アンド・ディー・マネジメント株式会社 ３−フェニルピラゾロ［５，１−ｂ］チアゾール化合物
US20110178106A1 (en) * 2008-07-10 2011-07-21 Southern Research Institute Office Of Commercializ 5-quinolinone and imidazopyridine compounds and use thereof
CN102216298B (zh) * 2008-09-16 2014-04-16 Csir公司 作为hiv-1逆转录酶抑制剂的咪唑并吡啶和咪唑并嘧啶
SG10201503671TA (en) 2008-12-05 2015-06-29 Takeda Vaccines Inc Compositions, methods and uses for inducing viral growth
AR078521A1 (es) * 2009-10-08 2011-11-16 Eisai R&D Man Co Ltd Compuesto pirazolotiazol
SG10201605707UA (en) 2011-07-13 2016-09-29 Cytokinetics Inc Combination als therapy
WO2014076021A1 (en) * 2012-11-14 2014-05-22 F. Hoffmann-La Roche Ag Imidazopyridine derivatives
BR112015020998B1 (pt) * 2013-03-14 2022-10-18 Galapagos Nv Compostos e composições farmacêuticas dos mesmos para o tratamento de distúrbios inflamatórios
WO2017160922A1 (en) 2016-03-16 2017-09-21 Kalyra Pharmaceuticals, Inc. Analgesic compounds
US11731967B2 (en) 2017-04-28 2023-08-22 Dana-Farber Cancer Institute, Inc. Inhibitors of TRIM33 and methods of use
WO2019070943A1 (en) * 2017-10-04 2019-04-11 Dana-Farber Cancer Institute, Inc. SMALL MOLECULE INHIBITION OF SALL4 TRANSCRIPTION FACTOR AND USES THEREOF

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EP0068378B1 (en) 1981-06-26 1986-03-05 Schering Corporation Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
NZ221996A (en) * 1986-10-07 1989-08-29 Yamanouchi Pharma Co Ltd Imidazo-pyridine derivatives and pharmaceutical compositions
TW274551B (pt) * 1991-04-16 1996-04-21 Takeda Pharm Industry Co Ltd
DE4327027A1 (de) * 1993-02-15 1994-08-18 Bayer Ag Imidazoazine
CA2218705A1 (en) * 1995-04-21 1996-10-24 Shinnippon Pharmaceutical Inc. Fused imidazo¬1,2-a|pyridines
WO2002002557A2 (en) * 2000-06-30 2002-01-10 Neurogen Corporation 2-phenylimidazo[1,2-a]pyridine derivatives: a new class of gaba brain receptor ligands

Also Published As

Publication number Publication date
WO2001027111A2 (de) 2001-04-19
CO5251378A1 (es) 2003-02-28
CN1391573A (zh) 2003-01-15
JP2003511451A (ja) 2003-03-25
CA2382919C (en) 2008-12-09
HK1047747A1 (en) 2003-03-07
UY26372A1 (es) 2000-12-29
US20030018032A1 (en) 2003-01-23
DE50005155D1 (de) 2004-03-04
PE20010634A1 (es) 2001-07-07
ATE258554T1 (de) 2004-02-15
DK1218382T3 (da) 2004-03-22
HUP0203052A2 (hu) 2003-01-28
AU7777100A (en) 2001-04-23
NO322754B1 (no) 2006-12-04
CZ20021210A3 (cs) 2002-08-14
HUP0203052A3 (en) 2004-06-28
EP1218382A2 (de) 2002-07-03
NO20021565L (no) 2002-05-27
ES2213611T3 (es) 2004-09-01
NZ518390A (en) 2003-10-31
KR100756592B1 (ko) 2007-09-10
CA2382919A1 (en) 2001-04-19
WO2001027111A3 (de) 2001-06-14
NZ518439A (en) 2003-10-31
KR20020038805A (ko) 2002-05-23
HK1047747B (zh) 2004-12-03
EP1218382B1 (de) 2004-01-28
RU2264402C2 (ru) 2005-11-20
US6638933B2 (en) 2003-10-28
PL355206A1 (en) 2004-04-05
AU779197B2 (en) 2005-01-13
SK286788B6 (sk) 2009-05-07
AR025962A1 (es) 2002-12-26
PT1218382E (pt) 2004-06-30
NO20021565D0 (no) 2002-04-03
SK4362002A3 (en) 2002-08-06
CN1257169C (zh) 2006-05-24

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Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements