NO20021563L - På seksringen substituerte, bisykliske imidazo-3-yl- aminderivater - Google Patents

På seksringen substituerte, bisykliske imidazo-3-yl- aminderivater

Info

Publication number
NO20021563L
NO20021563L NO20021563A NO20021563A NO20021563L NO 20021563 L NO20021563 L NO 20021563L NO 20021563 A NO20021563 A NO 20021563A NO 20021563 A NO20021563 A NO 20021563A NO 20021563 L NO20021563 L NO 20021563L
Authority
NO
Norway
Prior art keywords
substituted
ring
amine derivatives
bicyclic imidazo
imidazo
Prior art date
Application number
NO20021563A
Other languages
English (en)
Other versions
NO20021563D0 (no
Inventor
Matthias Gerlach
Corinna Maul
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19948434A external-priority patent/DE19948434A1/de
Priority claimed from DE1999148437 external-priority patent/DE19948437A1/de
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of NO20021563D0 publication Critical patent/NO20021563D0/no
Publication of NO20021563L publication Critical patent/NO20021563L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO20021563A 1999-10-08 2002-04-03 På seksringen substituerte, bisykliske imidazo-3-yl- aminderivater NO20021563L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19948434A DE19948434A1 (de) 1999-10-08 1999-10-08 Substanzbibliothek enthaltend bicyclische Imidazo-5-amine und/oder bicyclische Imidazo-3-amine
DE1999148437 DE19948437A1 (de) 1999-10-08 1999-10-08 Am Sechsring substituierte, bicyclische Imidazo-3-aminderivate
PCT/EP2000/009095 WO2001027110A2 (de) 1999-10-08 2000-09-18 Am sechsring substituierte, bicyclische imidazo-3-yl-aminderivate

Publications (2)

Publication Number Publication Date
NO20021563D0 NO20021563D0 (no) 2002-04-03
NO20021563L true NO20021563L (no) 2002-06-04

Family

ID=26055217

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20021563A NO20021563L (no) 1999-10-08 2002-04-03 På seksringen substituerte, bisykliske imidazo-3-yl- aminderivater

Country Status (27)

Country Link
US (1) US6849642B2 (no)
EP (1) EP1218380B1 (no)
JP (1) JP2003517466A (no)
KR (1) KR20020038804A (no)
CN (1) CN1222525C (no)
AR (1) AR025961A1 (no)
AT (1) ATE256684T1 (no)
AU (1) AU780823B2 (no)
BR (1) BR0014826A (no)
CA (1) CA2386813C (no)
CO (1) CO5210870A1 (no)
CZ (1) CZ300315B6 (no)
DE (1) DE50004817D1 (no)
DK (1) DK1218380T3 (no)
ES (1) ES2213044T3 (no)
HK (1) HK1047748B (no)
HU (1) HUP0203739A3 (no)
IL (2) IL148998A0 (no)
MX (1) MXPA02003547A (no)
NO (1) NO20021563L (no)
NZ (1) NZ518637A (no)
PE (1) PE20010631A1 (no)
PT (1) PT1218380E (no)
RU (1) RU2002110282A (no)
SK (1) SK286450B6 (no)
UY (1) UY26371A1 (no)
WO (1) WO2001027110A2 (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10043845A1 (de) * 2000-09-06 2002-03-14 Gruenenthal Gmbh Verfahren zur Messung der Aktivität der NO-Synthase
AU2002224927A1 (en) * 2000-12-13 2002-06-24 Basf Aktiengesellschaft Use of substituted imidazoazines, novel imidazoazines, methods for the production thereof, and agents containing these compounds
US7157460B2 (en) 2003-02-20 2007-01-02 Sugen Inc. Use of 8-amino-aryl-substituted imidazopyrazines as kinase inhibitors
US7186832B2 (en) 2003-02-20 2007-03-06 Sugen Inc. Use of 8-amino-aryl-substituted imidazopyrazines as kinase inhibitors
DE102004021716A1 (de) * 2004-04-30 2005-12-01 Grünenthal GmbH Substituierte Imidazo[1,2-a]pyridin-Verbindungen und Arzneimittel enthaltend substituierte Imidazo[1,2-a]pyridin-Verbindungen
DE102004044884A1 (de) 2004-09-14 2006-05-24 Grünenthal GmbH Substituierte bizyklische Imidazo-3-yl-amin-Verbindungen
DE102005016547A1 (de) * 2005-04-08 2006-10-12 Grünenthal GmbH Substituierte 5,6,7,8-Tetrahydro-imidazo(1,2-a)pyridin-2-ylamin-Verbindungen und deren Verwendung zur Herstellung von Arzneimitteln
WO2007028051A2 (en) 2005-09-02 2007-03-08 Abbott Laboratories Novel imidazo based heterocycles
NZ573015A (en) * 2006-05-31 2010-11-26 Galapagos Nv Triazolopyrazine compounds useful for the treatment of degenerative & inflammatory diseases
WO2008134553A1 (en) * 2007-04-26 2008-11-06 Xenon Pharmaceuticals Inc. Methods of using bicyclic compounds in treating sodium channel-mediated diseases
JP2010533680A (ja) 2007-07-18 2010-10-28 ノバルティス アーゲー 二環ヘテロアリール化合物およびそれらのキナーゼ阻害剤としての使用
CA2705947C (en) 2007-11-16 2016-08-09 Rigel Pharmaceuticals, Inc. Carboxamide, sulfonamide and amine compounds for metabolic disorders
ES2553340T3 (es) 2007-12-12 2015-12-07 Rigel Pharmaceuticals, Inc. Compuestos de carboxamida, sulfonamida y amina para trastornos metabólicos
CA2721670C (en) * 2008-04-15 2013-09-10 Eisai R&D Management Co., Ltd. 3-phenylpyrazolo[5,1-b]thiazole compound
CN102099357B (zh) 2008-04-23 2014-07-02 里格尔药品股份有限公司 用于治疗代谢障碍的甲酰胺化合物
WO2010032195A1 (en) * 2008-09-16 2010-03-25 Csir Imidazopyridines and imidazopyrimidines as hiv-i reverse transcriptase inhibitors
CA2758019C (en) * 2009-04-07 2014-09-23 University Of The Witwatersrand, Johannesburg Imidaz0[1,2-a] pyridine-6-carboxamide derivatives, their use for the treatment of colon cancer and their method of manufacture
AR078521A1 (es) * 2009-10-08 2011-11-16 Eisai R&D Man Co Ltd Compuesto pirazolotiazol
EP2547678B1 (en) * 2010-03-18 2016-03-16 Institut Pasteur Korea Anti-infective compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3489755A (en) 1966-08-03 1970-01-13 Pfizer & Co C Imidazo (1,2-b) pyridazines
DE3269604D1 (en) * 1981-06-26 1986-04-10 Schering Corp Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
NZ221996A (en) * 1986-10-07 1989-08-29 Yamanouchi Pharma Co Ltd Imidazo-pyridine derivatives and pharmaceutical compositions
TW274551B (no) * 1991-04-16 1996-04-21 Takeda Pharm Industry Co Ltd
EP0822194A4 (en) * 1995-04-21 1998-04-29 Shinnippon Pharmaceutical Inc ANNELLLIED IMIDAZO [1,2-a] PYRIDINE

Also Published As

Publication number Publication date
WO2001027110A2 (de) 2001-04-19
NO20021563D0 (no) 2002-04-03
CZ300315B6 (cs) 2009-04-15
IL148998A0 (en) 2002-11-10
IL148998A (en) 2006-12-31
CO5210870A1 (es) 2002-10-30
MXPA02003547A (es) 2002-09-18
SK286450B6 (sk) 2008-10-07
AU7519900A (en) 2001-04-23
AU780823B2 (en) 2005-04-21
CA2386813C (en) 2008-09-02
CN1222525C (zh) 2005-10-12
RU2002110282A (ru) 2003-12-20
BR0014826A (pt) 2002-08-27
CZ20021243A3 (cs) 2003-12-17
EP1218380B1 (de) 2003-12-17
PL364866A1 (en) 2004-12-27
US20020183327A1 (en) 2002-12-05
SK4612002A3 (en) 2002-09-10
CA2386813A1 (en) 2001-04-19
DE50004817D1 (de) 2004-01-29
AR025961A1 (es) 2002-12-26
JP2003517466A (ja) 2003-05-27
US6849642B2 (en) 2005-02-01
HK1047748A1 (en) 2003-03-07
HK1047748B (zh) 2004-10-21
EP1218380A2 (de) 2002-07-03
CN1402727A (zh) 2003-03-12
WO2001027110A3 (de) 2001-09-20
KR20020038804A (ko) 2002-05-23
ATE256684T1 (de) 2004-01-15
UY26371A1 (es) 2000-10-31
DK1218380T3 (da) 2004-03-15
HUP0203739A2 (hu) 2003-02-28
ES2213044T3 (es) 2004-08-16
PE20010631A1 (es) 2001-07-07
PT1218380E (pt) 2004-05-31
NZ518637A (en) 2004-12-24
HUP0203739A3 (en) 2004-07-28

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Legal Events

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