BR0114913A - Inibidores de metaloproteinase de espiro-pirimidina-2,4,6-triona - Google Patents

Inibidores de metaloproteinase de espiro-pirimidina-2,4,6-triona

Info

Publication number
BR0114913A
BR0114913A BR0114913-0A BR0114913A BR0114913A BR 0114913 A BR0114913 A BR 0114913A BR 0114913 A BR0114913 A BR 0114913A BR 0114913 A BR0114913 A BR 0114913A
Authority
BR
Brazil
Prior art keywords
spiro
pyrimidine
metalloproteinase inhibitors
trione metalloproteinase
trione
Prior art date
Application number
BR0114913-0A
Other languages
English (en)
Portuguese (pt)
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of BR0114913A publication Critical patent/BR0114913A/pt

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10Spiro-condensed systems
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10Spiro-condensed systems

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pregnancy & Childbirth (AREA)
  • Virology (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
BR0114913-0A 2000-10-26 2001-10-23 Inibidores de metaloproteinase de espiro-pirimidina-2,4,6-triona BR0114913A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24338900P 2000-10-26 2000-10-26
PCT/IB2001/001986 WO2002034753A2 (en) 2000-10-26 2001-10-23 Spiro-pyrimidine-2,4,6-trione metalloproteinase inhibitors

Publications (1)

Publication Number Publication Date
BR0114913A true BR0114913A (pt) 2003-07-01

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ID=22918584

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0114913-0A BR0114913A (pt) 2000-10-26 2001-10-23 Inibidores de metaloproteinase de espiro-pirimidina-2,4,6-triona

Country Status (32)

Country Link
EP (1) EP1332146A2 (is)
JP (1) JP2004518635A (is)
KR (1) KR20040004412A (is)
CN (1) CN1501937A (is)
AP (1) AP2001002318A0 (is)
AR (1) AR035069A1 (is)
AU (1) AU2002210813A1 (is)
BG (1) BG107653A (is)
BR (1) BR0114913A (is)
CA (1) CA2425283A1 (is)
CZ (1) CZ20031083A3 (is)
EA (1) EA005762B1 (is)
EC (1) ECSP034567A (is)
EE (1) EE200300196A (is)
GT (1) GT200100213A (is)
HN (1) HN2001000244A (is)
HR (1) HRP20030332A2 (is)
HU (1) HUP0301577A3 (is)
IL (1) IL154948A0 (is)
IS (1) IS6762A (is)
MA (1) MA26957A1 (is)
MX (1) MXPA03003735A (is)
NO (1) NO20031853L (is)
OA (1) OA12529A (is)
PA (1) PA8531401A1 (is)
PE (1) PE20020589A1 (is)
PL (1) PL366201A1 (is)
SK (1) SK4972003A3 (is)
SV (1) SV2003000705A (is)
TN (1) TNSN01149A1 (is)
WO (1) WO2002034753A2 (is)
ZA (1) ZA200302190B (is)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
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DOP2002000333A (es) 2001-02-14 2002-09-30 Warner Lambert Co Derivados de acido isoftalico como inhibidores de metaloproteinasas de la matriz
ES2231708T3 (es) 2001-02-14 2005-05-16 Warner-Lambert Company Llc Benzotiadicinas inhibidoras de metaloproteinasa de matriz.
DOP2002000332A (es) 2001-02-14 2002-08-30 Warner Lambert Co Inhibidores de piridina de metaloproteinasas de la matriz
EP1368323B1 (en) 2001-02-14 2010-06-30 Warner-Lambert Company LLC Pyrimidine matrix metalloproteinase inhibitors
PA8539501A1 (es) 2001-02-14 2002-09-30 Warner Lambert Co Compuestos triazolo como inhibidores de mmp
US6924276B2 (en) 2001-09-10 2005-08-02 Warner-Lambert Company Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors
CA2462442A1 (en) 2001-10-12 2003-04-24 Warner-Lambert Company Llc Alkyne matrix metalloproteinase inhibitors
US6962922B2 (en) 2001-10-12 2005-11-08 Warner-Lambert Company Llc Alkynylated quinazoline compounds
US6894057B2 (en) 2002-03-08 2005-05-17 Warner-Lambert Company Oxo-azabicyclic compounds
WO2003091252A1 (en) * 2002-04-25 2003-11-06 Bristol-Myers Squibb Company Spirobarbituric acid derivatives useful as inhibitors of matrix metalloproteases
EP1501833B1 (en) * 2002-04-26 2005-11-02 Pfizer Products Inc. N-substituted-heteroaryloxy-aryl-spiro-pyrimidine-2,4,6-trione metalloproteinase inhibitors
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