EA200300306A1 - Спиропиримидин-2,4,6-трионовые ингибиторы металлопротеиназы - Google Patents

Спиропиримидин-2,4,6-трионовые ингибиторы металлопротеиназы

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Publication number
EA200300306A1
EA200300306A1 EA200300306A EA200300306A EA200300306A1 EA 200300306 A1 EA200300306 A1 EA 200300306A1 EA 200300306 A EA200300306 A EA 200300306A EA 200300306 A EA200300306 A EA 200300306A EA 200300306 A1 EA200300306 A1 EA 200300306A1
Authority
EA
Eurasian Patent Office
Prior art keywords
trione
spyropyrimidin
metalproteinase
inhibitors
spiropirimidine
Prior art date
Application number
EA200300306A
Other languages
English (en)
Other versions
EA005762B1 (ru
Inventor
Брайан Скотт Бронк
Марк Карл Ноу
Мартин Джеймс Уайтс
Original Assignee
Пфайзер Продактс Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Пфайзер Продактс Инк. filed Critical Пфайзер Продактс Инк.
Publication of EA200300306A1 publication Critical patent/EA200300306A1/ru
Publication of EA005762B1 publication Critical patent/EA005762B1/ru

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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
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Abstract

Настоящее изобретение относится к 5-спиропиримидин-2,4,6-трионовым ингибиторам металлопротеиназы формулы, где указанное "А" представляет собой 5-7-членное гетероциклическое кольцо, как определено в описании, и к фармацевтическим композициям и способам лечения воспаления, рака и других расстройств.Отчет о международном поиске был опубликован 2002.08.15.
EA200300306A 2000-10-26 2001-10-23 Спиро-пиримидин-2,4,6-трионовые ингибиторы металлопротеиназы EA005762B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24338900P 2000-10-26 2000-10-26
PCT/IB2001/001986 WO2002034753A2 (en) 2000-10-26 2001-10-23 Spiro-pyrimidine-2,4,6-trione metalloproteinase inhibitors

Publications (2)

Publication Number Publication Date
EA200300306A1 true EA200300306A1 (ru) 2003-08-28
EA005762B1 EA005762B1 (ru) 2005-06-30

Family

ID=22918584

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200300306A EA005762B1 (ru) 2000-10-26 2001-10-23 Спиро-пиримидин-2,4,6-трионовые ингибиторы металлопротеиназы

Country Status (32)

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EP (1) EP1332146A2 (ru)
JP (1) JP2004518635A (ru)
KR (1) KR20040004412A (ru)
CN (1) CN1501937A (ru)
AP (1) AP2001002318A0 (ru)
AR (1) AR035069A1 (ru)
AU (1) AU2002210813A1 (ru)
BG (1) BG107653A (ru)
BR (1) BR0114913A (ru)
CA (1) CA2425283A1 (ru)
CZ (1) CZ20031083A3 (ru)
EA (1) EA005762B1 (ru)
EC (1) ECSP034567A (ru)
EE (1) EE200300196A (ru)
GT (1) GT200100213A (ru)
HN (1) HN2001000244A (ru)
HR (1) HRP20030332A2 (ru)
HU (1) HUP0301577A3 (ru)
IL (1) IL154948A0 (ru)
IS (1) IS6762A (ru)
MA (1) MA26957A1 (ru)
MX (1) MXPA03003735A (ru)
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EP1332146A2 (en) 2003-08-06
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MXPA03003735A (es) 2003-07-28
AU2002210813A1 (en) 2002-05-06
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OA12529A (en) 2006-06-02
AR035069A1 (es) 2004-04-14
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EA005762B1 (ru) 2005-06-30
JP2004518635A (ja) 2004-06-24
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CA2425283A1 (en) 2002-05-02
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