BR0015275A - Cristais de inibidores de permutadores sódio-hidrogênio do tipo 1 - Google Patents

Cristais de inibidores de permutadores sódio-hidrogênio do tipo 1

Info

Publication number
BR0015275A
BR0015275A BR0015275-7A BR0015275A BR0015275A BR 0015275 A BR0015275 A BR 0015275A BR 0015275 A BR0015275 A BR 0015275A BR 0015275 A BR0015275 A BR 0015275A
Authority
BR
Brazil
Prior art keywords
crystals
sodium
type
nhe
hydrogen exchanger
Prior art date
Application number
BR0015275-7A
Other languages
English (en)
Inventor
Lyle Robinson Brostrom
Terrence Joseph Connolly
Zheng Jane Li
Susan Lee Orrill
Bharat Kiritkumar Shah
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of BR0015275A publication Critical patent/BR0015275A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Toxicology (AREA)
  • Surgery (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Treatment Of Water By Ion Exchange (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"CRISTAIS DE INIBIDORES DE PERMUTADORES SóDIO-HIDROGêNIO DO TIPO 1". Cristais inibidores de NHE-1, métodos para usar tais cristais inibidores de NHE-1, e composições farmacêuticas contendo tais cristais inibidores de NHE-1. Os cristais inibidores de NHE-1, são úteis para a redução de danos nos tecidos resultantes da isquemia dos tecidos.
BR0015275-7A 1999-10-29 2000-10-09 Cristais de inibidores de permutadores sódio-hidrogênio do tipo 1 BR0015275A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16237499P 1999-10-29 1999-10-29
PCT/IB2000/001460 WO2001030759A2 (en) 1999-10-29 2000-10-09 Sodium-hydrogen exchanger type 1 inhibitor crystals

Publications (1)

Publication Number Publication Date
BR0015275A true BR0015275A (pt) 2002-07-16

Family

ID=22585355

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0015275-7A BR0015275A (pt) 1999-10-29 2000-10-09 Cristais de inibidores de permutadores sódio-hidrogênio do tipo 1

Country Status (44)

Country Link
EP (1) EP1224179B1 (pt)
JP (1) JP2003512455A (pt)
KR (1) KR100464526B1 (pt)
CN (2) CN1205205C (pt)
AP (1) AP2002002493A0 (pt)
AR (1) AR029402A1 (pt)
AT (1) ATE271047T1 (pt)
AU (1) AU778573B2 (pt)
BG (1) BG106729A (pt)
BR (1) BR0015275A (pt)
CA (1) CA2389020A1 (pt)
CO (1) CO5271714A1 (pt)
CZ (1) CZ20021332A3 (pt)
DE (1) DE60012208T2 (pt)
DK (1) DK1224179T3 (pt)
DZ (1) DZ3463A1 (pt)
EA (1) EA004937B1 (pt)
EE (1) EE200200227A (pt)
ES (1) ES2222923T3 (pt)
GE (1) GEP20043222B (pt)
GT (1) GT200000180A (pt)
HK (1) HK1048472B (pt)
HR (1) HRP20020366B1 (pt)
HU (1) HUP0204009A3 (pt)
IL (1) IL148581A0 (pt)
IS (1) IS6302A (pt)
MA (1) MA26840A1 (pt)
MX (1) MXPA02004358A (pt)
NO (1) NO20021821L (pt)
NZ (1) NZ517738A (pt)
OA (1) OA12080A (pt)
PA (1) PA8505501A1 (pt)
PE (1) PE20010764A1 (pt)
PL (1) PL354869A1 (pt)
PT (1) PT1224179E (pt)
SI (1) SI1224179T1 (pt)
SK (1) SK5312002A3 (pt)
SV (1) SV2002000209A (pt)
TN (1) TNSN00210A1 (pt)
TR (1) TR200201167T2 (pt)
UA (1) UA72002C2 (pt)
WO (1) WO2001030759A2 (pt)
YU (1) YU31502A (pt)
ZA (1) ZA200203295B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6441176B1 (en) 1999-10-29 2002-08-27 Pfizer Inc. Method for preparing sodium-hydrogen exchanger type 1 inhibitor
EP1355899A1 (en) * 2001-01-31 2003-10-29 Pfizer Products Inc. Ethanolates of sodium-hydrogen exchanger type-1 inhibitor
MXPA04006615A (es) * 2002-01-30 2004-10-04 Pfizer Prod Inc Composiciones farmaceuticas de mesilato de zoniporida y procedimientos para mejorar la solubilidad de la zoniporida.
BR0309707A (pt) * 2002-05-02 2005-02-09 Pfizer Prod Inc Tratamento de diabetes e complicações diabéticas com inibidores nhe-1

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1454902A1 (en) * 1998-02-27 2004-09-08 Pfizer Products Inc. N- (substituted five-membered di-or triaza diunsaturated ring)carbonyl guanidine derivateives for the treatment of ischemia

Also Published As

Publication number Publication date
DK1224179T3 (da) 2004-10-25
AP2002002493A0 (en) 2002-06-30
KR100464526B1 (ko) 2005-01-03
AR029402A1 (es) 2003-06-25
ATE271047T1 (de) 2004-07-15
IL148581A0 (en) 2002-09-12
UA72002C2 (en) 2005-01-17
SI1224179T1 (en) 2004-10-31
TR200201167T2 (tr) 2002-08-21
ZA200203295B (en) 2003-06-25
HK1048472B (zh) 2005-09-16
DZ3463A1 (fr) 2001-05-03
MXPA02004358A (es) 2002-11-07
OA12080A (en) 2003-08-25
CN1636991A (zh) 2005-07-13
HUP0204009A3 (en) 2004-07-28
IS6302A (is) 2002-03-15
AU7441500A (en) 2001-05-08
WO2001030759A2 (en) 2001-05-03
HUP0204009A2 (hu) 2003-03-28
HRP20020366B1 (en) 2005-04-30
SV2002000209A (es) 2002-07-16
ES2222923T3 (es) 2005-02-16
PT1224179E (pt) 2004-10-29
GEP20043222B (en) 2004-04-26
EA004937B1 (ru) 2004-10-28
DE60012208T2 (de) 2005-07-21
TNSN00210A1 (fr) 2005-11-10
CO5271714A1 (es) 2003-04-30
EP1224179B1 (en) 2004-07-14
CN1384829A (zh) 2002-12-11
CA2389020A1 (en) 2001-05-03
PL354869A1 (en) 2004-03-08
AU778573B2 (en) 2004-12-09
EE200200227A (et) 2003-06-16
MA26840A1 (fr) 2004-12-20
JP2003512455A (ja) 2003-04-02
NO20021821D0 (no) 2002-04-18
HK1048472A1 (en) 2003-04-04
EA200200416A1 (ru) 2002-10-31
BG106729A (bg) 2002-12-29
PE20010764A1 (es) 2001-07-23
HRP20020366A2 (en) 2004-02-29
CZ20021332A3 (cs) 2002-10-16
GT200000180A (es) 2002-04-11
PA8505501A1 (es) 2003-09-05
DE60012208D1 (de) 2004-08-19
SK5312002A3 (en) 2003-01-09
KR20020040918A (ko) 2002-05-30
WO2001030759A3 (en) 2001-09-13
NO20021821L (no) 2002-04-18
CN1205205C (zh) 2005-06-08
NZ517738A (en) 2005-06-24
YU31502A (sh) 2004-12-31
EP1224179A2 (en) 2002-07-24

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2008 DE 30/06/2009.