BR0005122A - Método para a preparação de inibidor de permutador de sódio-hidrogênio do tipo 1 - Google Patents

Método para a preparação de inibidor de permutador de sódio-hidrogênio do tipo 1

Info

Publication number
BR0005122A
BR0005122A BR0005122-5A BR0005122A BR0005122A BR 0005122 A BR0005122 A BR 0005122A BR 0005122 A BR0005122 A BR 0005122A BR 0005122 A BR0005122 A BR 0005122A
Authority
BR
Brazil
Prior art keywords
sodium
preparation
type
hydrogen exchanger
exchanger inhibitor
Prior art date
Application number
BR0005122-5A
Other languages
English (en)
Inventor
Norma Jacqueline Tom
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of BR0005122A publication Critical patent/BR0005122A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/10—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by doubly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Patente de Invenção: <B>"MéTODO PARA A PREPARAçãO DE INIBIDOR DE PERMUTADOR DE SóDIO-HIDROGêNIO DO TIPO 1"<D>. São divulgados métodos de preparação de inibidores de NHE-1. Os inibidores de NHE-1 são úteis para a redução dos danos nos tecidos que resultam da isquemia nos tecidos.
BR0005122-5A 1999-10-29 2000-10-30 Método para a preparação de inibidor de permutador de sódio-hidrogênio do tipo 1 BR0005122A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16237799P 1999-10-29 1999-10-29

Publications (1)

Publication Number Publication Date
BR0005122A true BR0005122A (pt) 2001-06-19

Family

ID=22585372

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0005122-5A BR0005122A (pt) 1999-10-29 2000-10-30 Método para a preparação de inibidor de permutador de sódio-hidrogênio do tipo 1

Country Status (20)

Country Link
US (1) US6441176B1 (pt)
EP (1) EP1101763A3 (pt)
JP (1) JP3342475B2 (pt)
KR (2) KR100449595B1 (pt)
CN (1) CN1146557C (pt)
AR (1) AR029188A1 (pt)
AU (1) AU779106B2 (pt)
BR (1) BR0005122A (pt)
CA (1) CA2324640A1 (pt)
CZ (1) CZ20004018A3 (pt)
HK (1) HK1036057A1 (pt)
HU (1) HUP0004187A2 (pt)
ID (1) ID27904A (pt)
IL (1) IL139198A0 (pt)
PL (1) PL343542A1 (pt)
RU (1) RU2190605C2 (pt)
TR (1) TR200003143A2 (pt)
TW (1) TWI221152B (pt)
YU (1) YU62900A (pt)
ZA (1) ZA200006007B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6852733B2 (en) 2000-04-28 2005-02-08 Pfizer Inc. Sodium-hydrogen exchanger type 1 inhibitor
CA2436539A1 (en) * 2001-01-31 2002-08-08 Pfizer Products Inc. Ethanolates of sodium-hydrogen exchanger type-1 inhibitor
JP2005511787A (ja) * 2001-12-19 2005-04-28 ファイザー・プロダクツ・インク ナトリウム−水素交換１型阻害物質を調製する方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4028381A (en) * 1975-05-05 1977-06-07 Ciba-Geigy Corporation Pyrazolobenzazepines
US6184380B1 (en) * 1999-01-25 2001-02-06 Pfizer Inc. Process for preparing naphthyridones and intermediates
EP1454902A1 (en) 1998-02-27 2004-09-08 Pfizer Products Inc. N- (substituted five-membered di-or triaza diunsaturated ring)carbonyl guanidine derivateives for the treatment of ischemia
UA72002C2 (en) 1999-10-29 2005-01-17 Pfizer Prod Inc Inhibitors crystals of sodium-hydrogen exchange of 1 type, a method for the preparation thereof (variants), a pharmaceuticalcomposition based thereon and a method for the reduction of tissue damage

Also Published As

Publication number Publication date
EP1101763A2 (en) 2001-05-23
CZ20004018A3 (cs) 2002-04-17
JP3342475B2 (ja) 2002-11-11
IL139198A0 (en) 2001-11-25
CN1146557C (zh) 2004-04-21
TR200003143A2 (tr) 2001-05-21
KR20010060211A (ko) 2001-07-06
ZA200006007B (en) 2002-04-26
TWI221152B (en) 2004-09-21
HK1036057A1 (en) 2003-07-10
YU62900A (sh) 2003-08-29
HU0004187D0 (pt) 2001-01-29
AU779106B2 (en) 2005-01-06
KR100449595B1 (ko) 2004-09-21
PL343542A1 (en) 2001-05-07
CN1295070A (zh) 2001-05-16
KR20030061767A (ko) 2003-07-22
ID27904A (id) 2001-05-03
US6441176B1 (en) 2002-08-27
CA2324640A1 (en) 2001-04-29
HUP0004187A2 (hu) 2002-11-28
KR100443851B1 (ko) 2004-08-11
AU6133300A (en) 2001-05-03
JP2001158784A (ja) 2001-06-12
RU2190605C2 (ru) 2002-10-10
AR029188A1 (es) 2003-06-18
EP1101763A3 (en) 2002-04-24

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1962 DE 12/08/2008.