BR0112028A - Inibidores de farnesil transferase - Google Patents

Inibidores de farnesil transferase

Info

Publication number
BR0112028A
BR0112028A BR0112028-0A BR0112028A BR0112028A BR 0112028 A BR0112028 A BR 0112028A BR 0112028 A BR0112028 A BR 0112028A BR 0112028 A BR0112028 A BR 0112028A
Authority
BR
Brazil
Prior art keywords
farnesyl transferase
transferase inhibitors
transferase
inhibitors
inhibiting
Prior art date
Application number
BR0112028-0A
Other languages
English (en)
Inventor
Akiyo K Claiborne
Stephen L Ii Gwaltney
Lisa A Hasvold
Qun Li
Tomgmei Li
Nan-Horng Lin
Robert A Mantei
Todd W Rockway
Hing L Sham
Gerard M Sullivan
Yunsong Tong
Gary T Wang
Le Wang
Xilu Wang
Weibo Wang
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of BR0112028A publication Critical patent/BR0112028A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

"INIBIDORES DE FARNESIL TRANSFERASE". Os imidazóis e os tiazóis substituídos tendo a fórmula (I) são úteis para a inibição da farnesil transferase. As composições inibidoras da farnesil transferase e os métodos de inibir a farnesil transferase são também divulgados.
BR0112028-0A 2000-11-30 2001-11-30 Inibidores de farnesil transferase BR0112028A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72723000A 2000-11-30 2000-11-30
US09/912,677 US20020115640A1 (en) 2000-11-30 2001-07-25 Farnesyltransferase inhibitors
PCT/US2001/043168 WO2002074747A1 (en) 2000-11-30 2001-11-30 Farnesyltransferase inhibitors

Publications (1)

Publication Number Publication Date
BR0112028A true BR0112028A (pt) 2004-02-17

Family

ID=24921844

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0112028-0A BR0112028A (pt) 2000-11-30 2001-11-30 Inibidores de farnesil transferase

Country Status (31)

Country Link
US (1) US20020115640A1 (pt)
EP (1) EP1339695B1 (pt)
JP (1) JP2004519503A (pt)
KR (1) KR20030060968A (pt)
CN (1) CN1487924A (pt)
AR (1) AR035375A1 (pt)
AT (1) ATE323681T1 (pt)
BG (1) BG107908A (pt)
BR (1) BR0112028A (pt)
CA (1) CA2430619A1 (pt)
CY (1) CY1106104T1 (pt)
CZ (1) CZ20031804A3 (pt)
DE (1) DE60118955T2 (pt)
DK (1) DK1339695T3 (pt)
EC (1) ECSP034634A (pt)
ES (1) ES2261340T3 (pt)
HK (1) HK1059260A1 (pt)
HU (1) HUP0600331A2 (pt)
IL (2) IL156212A0 (pt)
MX (1) MXPA03004879A (pt)
MY (1) MY136181A (pt)
NO (1) NO20032471L (pt)
NZ (1) NZ526313A (pt)
PE (1) PE20020687A1 (pt)
PL (1) PL363637A1 (pt)
PT (1) PT1339695E (pt)
SA (1) SA01220565B1 (pt)
SI (1) SI1339695T1 (pt)
SK (1) SK286686B6 (pt)
UY (1) UY27046A1 (pt)
WO (1) WO2002074747A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2606226A1 (en) * 2005-04-27 2006-11-02 University Of Florida Research Foundation, Inc. Materials and methods for enhanced degradation of mutant proteins associated with human disease
JP4592548B2 (ja) * 2005-08-24 2010-12-01 株式会社エヌ・ティ・ティ・ドコモ 送信電力制御方法及び移動通信システム
US7722316B2 (en) * 2005-09-13 2010-05-25 Rolls-Royce Power Engineering Plc Acoustic viscous damper for centrifugal gas compressor
US7790770B2 (en) * 2005-11-23 2010-09-07 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
TW200806284A (en) * 2006-03-31 2008-02-01 Alcon Mfg Ltd Prenyltransferase inhibitors for ocular hypertension control and the treatment of glaucoma
US8084477B2 (en) * 2007-10-31 2011-12-27 Bristol-Myers Squibb Company Alpha-(N-sulfonamido)acetamide compound as an inhibitor of beta amyloid peptide production
WO2009158011A1 (en) * 2008-06-26 2009-12-30 Amgen Inc. Alkynyl alcohols as kinase inhibitors
US20130324521A1 (en) * 2010-11-26 2013-12-05 Reza Ghotbi Implant for treating or preventing an aneurysm
CN105693617B (zh) * 2014-11-24 2018-06-08 中国科学院大连化学物理研究所 一种tmsn3参与的还原环化反应制备4-咪唑甲醛衍生物的方法
EP3902100A1 (en) 2015-10-07 2021-10-27 Tc1 Llc Resonant power transfer systems having efficiency optimization based on receiver impedance

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2249607A1 (en) * 1996-04-03 1997-10-09 Neville J. Anthony Inhibitors of farnesyl-protein transferase
US6297239B1 (en) * 1997-10-08 2001-10-02 Merck & Co., Inc. Inhibitors of prenyl-protein transferase
ES2237125T3 (es) * 1998-08-27 2005-07-16 Pfizer Products Inc. Derivados de quinolin-2-ona utiles como agentes anticancerigenos.

Also Published As

Publication number Publication date
SK286686B6 (sk) 2009-03-05
ECSP034634A (es) 2003-07-25
CY1106104T1 (el) 2011-06-08
DE60118955D1 (de) 2006-05-24
PT1339695E (pt) 2006-08-31
WO2002074747A1 (en) 2002-09-26
IL156212A0 (en) 2003-12-23
NO20032471D0 (no) 2003-05-30
DK1339695T3 (da) 2006-07-31
JP2004519503A (ja) 2004-07-02
DE60118955T2 (de) 2007-01-04
UY27046A1 (es) 2002-07-31
KR20030060968A (ko) 2003-07-16
IL156212A (en) 2008-11-26
NO20032471L (no) 2003-07-25
PL363637A1 (en) 2004-11-29
ES2261340T3 (es) 2006-11-16
NZ526313A (en) 2004-11-26
SK8232003A3 (en) 2004-01-08
HK1059260A1 (en) 2004-06-25
SA01220565B1 (ar) 2007-01-27
CN1487924A (zh) 2004-04-07
ATE323681T1 (de) 2006-05-15
SI1339695T1 (sl) 2006-10-31
EP1339695B1 (en) 2006-04-19
BG107908A (bg) 2004-01-30
MXPA03004879A (es) 2004-05-04
MY136181A (en) 2008-08-29
CA2430619A1 (en) 2002-09-26
CZ20031804A3 (cs) 2003-11-12
AR035375A1 (es) 2004-05-12
PE20020687A1 (es) 2002-08-03
US20020115640A1 (en) 2002-08-22
HUP0600331A2 (en) 2006-10-28
EP1339695A1 (en) 2003-09-03

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: CONFORME ARTIGO 10O DA RESOLUCAO 124/06, CABE SER ARQUIVADO REFERENTE AO NAO RECOLHIMENTO DA 9A E 10A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2144 DE 07/02/2012.