CY1106104T1 - Αναστολεις φαρναζυλτρανσφepασης - Google Patents
Αναστολεις φαρναζυλτρανσφepασηςInfo
- Publication number
- CY1106104T1 CY1106104T1 CY20061100852T CY061100852T CY1106104T1 CY 1106104 T1 CY1106104 T1 CY 1106104T1 CY 20061100852 T CY20061100852 T CY 20061100852T CY 061100852 T CY061100852 T CY 061100852T CY 1106104 T1 CY1106104 T1 CY 1106104T1
- Authority
- CY
- Cyprus
- Prior art keywords
- transfepase
- farnazyl
- inhibitors
- farnesyltransferase
- inhibiting
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title 1
- 102000007317 Farnesyltranstransferase Human genes 0.000 abstract 3
- 108010007508 Farnesyltranstransferase Proteins 0.000 abstract 3
- 230000002401 inhibitory effect Effects 0.000 abstract 3
- 150000002460 imidazoles Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003557 thiazoles Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Abstract
Υποκατεστημένα ιμιδαζόλια και θειαζόλια που έχουν το τύπο (I), είναι χρήσιμα για αναστολή φαρνεζυλτρανσφεράσης. Αποκαλύπτονται επίσης ανασταλτικές της φαρναζυλτρανσφεράσης συνθέσεις και μέθοδοι αναστολής φαρνεζυλτρανσφεράσης σε έναν ασθενή.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72723000A | 2000-11-30 | 2000-11-30 | |
| US09/912,677 US20020115640A1 (en) | 2000-11-30 | 2001-07-25 | Farnesyltransferase inhibitors |
| PCT/US2001/043168 WO2002074747A1 (en) | 2000-11-30 | 2001-11-30 | Farnesyltransferase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1106104T1 true CY1106104T1 (el) | 2011-06-08 |
Family
ID=24921844
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20061100852T CY1106104T1 (el) | 2000-11-30 | 2006-06-23 | Αναστολεις φαρναζυλτρανσφepασης |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US20020115640A1 (el) |
| EP (1) | EP1339695B1 (el) |
| JP (1) | JP2004519503A (el) |
| KR (1) | KR20030060968A (el) |
| CN (1) | CN1487924A (el) |
| AR (1) | AR035375A1 (el) |
| AT (1) | ATE323681T1 (el) |
| BG (1) | BG107908A (el) |
| BR (1) | BR0112028A (el) |
| CA (1) | CA2430619A1 (el) |
| CY (1) | CY1106104T1 (el) |
| CZ (1) | CZ20031804A3 (el) |
| DE (1) | DE60118955T2 (el) |
| DK (1) | DK1339695T3 (el) |
| EC (1) | ECSP034634A (el) |
| ES (1) | ES2261340T3 (el) |
| HK (1) | HK1059260A1 (el) |
| HU (1) | HUP0600331A2 (el) |
| IL (2) | IL156212A0 (el) |
| MX (1) | MXPA03004879A (el) |
| MY (1) | MY136181A (el) |
| NO (1) | NO20032471L (el) |
| NZ (1) | NZ526313A (el) |
| PE (1) | PE20020687A1 (el) |
| PL (1) | PL363637A1 (el) |
| PT (1) | PT1339695E (el) |
| SA (1) | SA01220565B1 (el) |
| SI (1) | SI1339695T1 (el) |
| SK (1) | SK286686B6 (el) |
| UY (1) | UY27046A1 (el) |
| WO (1) | WO2002074747A1 (el) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0612925A2 (pt) * | 2005-04-27 | 2010-12-07 | Univ Florida Res Foudation Inc | uso de um composto, composição farmacêutica e kit |
| JP4592548B2 (ja) * | 2005-08-24 | 2010-12-01 | 株式会社エヌ・ティ・ティ・ドコモ | 送信電力制御方法及び移動通信システム |
| US7722316B2 (en) * | 2005-09-13 | 2010-05-25 | Rolls-Royce Power Engineering Plc | Acoustic viscous damper for centrifugal gas compressor |
| US7790770B2 (en) | 2005-11-23 | 2010-09-07 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
| TW200806284A (en) * | 2006-03-31 | 2008-02-01 | Alcon Mfg Ltd | Prenyltransferase inhibitors for ocular hypertension control and the treatment of glaucoma |
| US8084477B2 (en) * | 2007-10-31 | 2011-12-27 | Bristol-Myers Squibb Company | Alpha-(N-sulfonamido)acetamide compound as an inhibitor of beta amyloid peptide production |
| CA2728767A1 (en) * | 2008-06-26 | 2009-12-30 | Amgen Inc. | Alkynyl alcohols as kinase inhibitors |
| EP2643031B1 (de) * | 2010-11-26 | 2015-06-24 | Reza Ghotbi | Implant zur behandlung oder prävention eines aneurysmas |
| CN105693617B (zh) * | 2014-11-24 | 2018-06-08 | 中国科学院大连化学物理研究所 | 一种tmsn3参与的还原环化反应制备4-咪唑甲醛衍生物的方法 |
| EP3902100A1 (en) | 2015-10-07 | 2021-10-27 | Tc1 Llc | Resonant power transfer systems having efficiency optimization based on receiver impedance |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997036901A1 (en) * | 1996-04-03 | 1997-10-09 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| US6297239B1 (en) * | 1997-10-08 | 2001-10-02 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
| CA2341739C (en) * | 1998-08-27 | 2005-07-12 | Pfizer Products Inc. | Quinolin-2-one derivatives useful as anticancer agents |
-
2001
- 2001-07-25 US US09/912,677 patent/US20020115640A1/en not_active Abandoned
- 2001-10-24 MY MYPI20014939A patent/MY136181A/en unknown
- 2001-11-29 UY UY27046A patent/UY27046A1/es not_active Application Discontinuation
- 2001-11-29 PE PE2001001198A patent/PE20020687A1/es not_active Application Discontinuation
- 2001-11-29 AR ARP010105568A patent/AR035375A1/es unknown
- 2001-11-30 PT PT01273519T patent/PT1339695E/pt unknown
- 2001-11-30 JP JP2002573756A patent/JP2004519503A/ja active Pending
- 2001-11-30 CZ CZ20031804A patent/CZ20031804A3/cs unknown
- 2001-11-30 CN CNA018223427A patent/CN1487924A/zh active Pending
- 2001-11-30 SK SK823-2003A patent/SK286686B6/sk not_active IP Right Cessation
- 2001-11-30 NZ NZ526313A patent/NZ526313A/en unknown
- 2001-11-30 HU HU0600331A patent/HUP0600331A2/hu unknown
- 2001-11-30 CA CA002430619A patent/CA2430619A1/en not_active Abandoned
- 2001-11-30 SI SI200130573T patent/SI1339695T1/sl unknown
- 2001-11-30 PL PL01363637A patent/PL363637A1/xx not_active Application Discontinuation
- 2001-11-30 KR KR10-2003-7007345A patent/KR20030060968A/ko not_active Application Discontinuation
- 2001-11-30 DE DE60118955T patent/DE60118955T2/de not_active Expired - Fee Related
- 2001-11-30 DK DK01273519T patent/DK1339695T3/da active
- 2001-11-30 BR BR0112028-0A patent/BR0112028A/pt not_active IP Right Cessation
- 2001-11-30 EP EP01273519A patent/EP1339695B1/en not_active Expired - Lifetime
- 2001-11-30 WO PCT/US2001/043168 patent/WO2002074747A1/en active IP Right Grant
- 2001-11-30 IL IL15621201A patent/IL156212A0/xx active IP Right Grant
- 2001-11-30 MX MXPA03004879A patent/MXPA03004879A/es active IP Right Grant
- 2001-11-30 ES ES01273519T patent/ES2261340T3/es not_active Expired - Lifetime
- 2001-11-30 AT AT01273519T patent/ATE323681T1/de not_active IP Right Cessation
- 2001-12-02 SA SA01220565A patent/SA01220565B1/ar unknown
-
2003
- 2003-05-29 IL IL156212A patent/IL156212A/en not_active IP Right Cessation
- 2003-05-30 NO NO20032471A patent/NO20032471L/no not_active Application Discontinuation
- 2003-05-30 EC EC2003004634A patent/ECSP034634A/es unknown
- 2003-06-13 BG BG107908A patent/BG107908A/bg unknown
-
2004
- 2004-01-27 HK HK04100551A patent/HK1059260A1/xx not_active IP Right Cessation
-
2006
- 2006-06-23 CY CY20061100852T patent/CY1106104T1/el unknown
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