ATE380797T1 - Prenyl-transferase inhibitoren - Google Patents
Prenyl-transferase inhibitorenInfo
- Publication number
- ATE380797T1 ATE380797T1 AT97924606T AT97924606T ATE380797T1 AT E380797 T1 ATE380797 T1 AT E380797T1 AT 97924606 T AT97924606 T AT 97924606T AT 97924606 T AT97924606 T AT 97924606T AT E380797 T1 ATE380797 T1 AT E380797T1
- Authority
- AT
- Austria
- Prior art keywords
- transferase inhibitors
- prenyl transferase
- image
- prenyl
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/672,474 US5773455A (en) | 1996-06-28 | 1996-06-28 | Inhibitors of prenyl transferases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE380797T1 true ATE380797T1 (de) | 2007-12-15 |
Family
ID=24698698
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97924606T ATE380797T1 (de) | 1996-06-28 | 1997-05-06 | Prenyl-transferase inhibitoren |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5773455A (de) |
| EP (1) | EP0932606B1 (de) |
| JP (1) | JP2000514056A (de) |
| CN (1) | CN1081187C (de) |
| AT (1) | ATE380797T1 (de) |
| AU (1) | AU726784B2 (de) |
| CA (1) | CA2254759C (de) |
| CZ (1) | CZ295437B6 (de) |
| DE (1) | DE69738373T2 (de) |
| ES (1) | ES2296309T3 (de) |
| IL (1) | IL127574A (de) |
| NZ (1) | NZ332559A (de) |
| PL (1) | PL189835B1 (de) |
| RU (1) | RU2186776C2 (de) |
| TW (1) | TW415945B (de) |
| WO (1) | WO1998000409A1 (de) |
| ZA (1) | ZA975727B (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2780892B1 (fr) * | 1998-07-08 | 2001-08-17 | Sod Conseils Rech Applic | Utilisation d'inhibiteurs de prenyltransferases pour preparer un medicament destine a traiter les pathologies qui resultent de la fixation membranaire de la proteine g heterotrimerique |
| US6410576B1 (en) * | 1998-07-28 | 2002-06-25 | Santen Pharmaceutical Co., Ltd. | Thiazolidine derivatives |
| EP1691812A4 (de) | 2003-11-20 | 2010-01-13 | Childrens Hosp Medical Center | Gtpase-hemmer und anwendungsverfahren |
| CA2573125A1 (en) * | 2004-08-27 | 2006-03-02 | Schwarz Pharma Ag | Novel use of peptide compounds for treating bone cancer pain, chemotherapy-and nucleoside-induced pain |
| US7759383B2 (en) | 2005-02-22 | 2010-07-20 | The Regents Of The University Of Michigan | Small molecule inhibitors of MDM2 and the uses thereof |
| BRPI0609172A2 (pt) * | 2005-02-22 | 2010-02-23 | Univ Michigan | inibidores de pequenas moléculas de mdm2 e usos destes |
| AU2006275528B2 (en) | 2005-07-29 | 2012-03-08 | Children's Hospital Medical Center | GTPase inhibitors and methods of use and crystal structure of Rac-1 GTPase |
| US8222288B2 (en) | 2006-08-30 | 2012-07-17 | The Regents Of The University Of Michigan | Small molecule inhibitors of MDM2 and the uses thereof |
| US7737174B2 (en) | 2006-08-30 | 2010-06-15 | The Regents Of The University Of Michigan | Indole inhibitors of MDM2 and the uses thereof |
| WO2011060049A2 (en) | 2009-11-12 | 2011-05-19 | The Regents Of The University Of Michigan | Spiro-oxindole mdm2 antagonists |
| JP6034784B2 (ja) | 2010-07-28 | 2016-11-30 | ジャンセン ダイアグノスティックス，エルエルシー | ファルネシルトランスフェラーゼ阻害剤による治療に対する急性白血病応答を判定するための方法 |
| CN103298818B (zh) | 2010-11-12 | 2016-06-29 | 密歇根大学董事会 | 螺-吲哚酮mdm2拮抗剂 |
| CN103717605B (zh) | 2011-05-11 | 2016-05-18 | 密执安州立大学董事会 | 螺-羟吲哚mdm2拮抗剂 |
| US9980942B2 (en) | 2012-05-02 | 2018-05-29 | Children's Hospital Medical Center | Rejuvenation of precursor cells |
| US10028503B2 (en) | 2014-06-18 | 2018-07-24 | Children's Hospital Medical Center | Platelet storage methods and compositions for same |
| PT3277842T (pt) | 2015-08-17 | 2019-09-05 | Kura Oncology Inc | Métodos de tratamento de doentes com cancro usando inibidores da farnesiltransferase |
| LT3534885T (lt) | 2016-11-03 | 2021-07-12 | Kura Oncology, Inc. | Farneziltransferazės inhibitoriai, skirti naudoti vėžio gydymui |
| WO2019113269A1 (en) | 2017-12-08 | 2019-06-13 | Kura Oncology, Inc. | Methods of treating cancer patients with farnesyltransferase inhibitors |
| TW202108170A (zh) | 2019-03-15 | 2021-03-01 | 美商庫拉腫瘤技術股份有限公司 | 以法呢基轉移酶(farnesyltransferase)抑制劑治療癌症患者之方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2118985A1 (en) * | 1993-04-02 | 1994-10-03 | Dinesh V. Patel | Heterocyclic inhibitors of farnesyl protein transferase |
| US5408385A (en) * | 1993-04-30 | 1995-04-18 | Robertshaw Controls Company | Control device and method of making the same |
| US5439918A (en) * | 1994-03-14 | 1995-08-08 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| CA2155448A1 (en) * | 1994-08-11 | 1996-02-12 | Katerina Leftheris | Inhibitors of farnesyl protein transferase |
| US5491164A (en) * | 1994-09-29 | 1996-02-13 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| AU4915796A (en) * | 1995-01-12 | 1996-07-31 | University Of Pittsburgh | Inhibitors of prenyl transferases |
-
1996
- 1996-06-28 US US08/672,474 patent/US5773455A/en not_active Expired - Fee Related
-
1997
- 1997-05-06 PL PL97330908A patent/PL189835B1/pl not_active IP Right Cessation
- 1997-05-06 CN CN97195906A patent/CN1081187C/zh not_active Expired - Fee Related
- 1997-05-06 AT AT97924606T patent/ATE380797T1/de not_active IP Right Cessation
- 1997-05-06 AU AU29988/97A patent/AU726784B2/en not_active Ceased
- 1997-05-06 CA CA002254759A patent/CA2254759C/en not_active Expired - Fee Related
- 1997-05-06 DE DE69738373T patent/DE69738373T2/de not_active Expired - Fee Related
- 1997-05-06 IL IL12757497A patent/IL127574A/en not_active IP Right Cessation
- 1997-05-06 EP EP97924606A patent/EP0932606B1/de not_active Expired - Lifetime
- 1997-05-06 ES ES97924606T patent/ES2296309T3/es not_active Expired - Lifetime
- 1997-05-06 JP JP10504097A patent/JP2000514056A/ja not_active Ceased
- 1997-05-06 NZ NZ332559A patent/NZ332559A/xx unknown
- 1997-05-06 CZ CZ19984180A patent/CZ295437B6/cs not_active IP Right Cessation
- 1997-05-06 RU RU99101796/04A patent/RU2186776C2/ru not_active IP Right Cessation
- 1997-05-06 WO PCT/US1997/007711 patent/WO1998000409A1/en active IP Right Grant
- 1997-06-26 TW TW086108981A patent/TW415945B/zh active
- 1997-06-27 ZA ZA9705727A patent/ZA975727B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2296309T3 (es) | 2008-04-16 |
| AU2998897A (en) | 1998-01-21 |
| CZ418098A3 (cs) | 1999-05-12 |
| PL330908A1 (en) | 1999-06-07 |
| AU726784B2 (en) | 2000-11-23 |
| CN1223642A (zh) | 1999-07-21 |
| CN1081187C (zh) | 2002-03-20 |
| IL127574A (en) | 2002-12-01 |
| CZ295437B6 (cs) | 2005-08-17 |
| CA2254759C (en) | 2007-02-13 |
| WO1998000409A1 (en) | 1998-01-08 |
| TW415945B (en) | 2000-12-21 |
| US5773455A (en) | 1998-06-30 |
| DE69738373D1 (de) | 2008-01-24 |
| DE69738373T2 (de) | 2008-12-04 |
| EP0932606A4 (de) | 2000-01-19 |
| NZ332559A (en) | 2000-05-26 |
| RU2186776C2 (ru) | 2002-08-10 |
| PL189835B1 (pl) | 2005-09-30 |
| JP2000514056A (ja) | 2000-10-24 |
| EP0932606B1 (de) | 2007-12-12 |
| ZA975727B (en) | 1998-01-26 |
| IL127574A0 (en) | 1999-10-28 |
| CA2254759A1 (en) | 1998-01-08 |
| EP0932606A1 (de) | 1999-08-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |