ES2175337T3 - Compuesto bifenilicos y su utilizacion como agentes estrogenicos. - Google Patents
Compuesto bifenilicos y su utilizacion como agentes estrogenicos.Info
- Publication number
- ES2175337T3 ES2175337T3 ES97902408T ES97902408T ES2175337T3 ES 2175337 T3 ES2175337 T3 ES 2175337T3 ES 97902408 T ES97902408 T ES 97902408T ES 97902408 T ES97902408 T ES 97902408T ES 2175337 T3 ES2175337 T3 ES 2175337T3
- Authority
- ES
- Spain
- Prior art keywords
- pct
- bifenilic
- compound
- estrogen agent
- sec
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/24—Halogenated derivatives
- C07C39/38—Halogenated derivatives with at least one hydroxy group on a condensed ring system containing two rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
- C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
- C07C217/20—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
- C07C39/15—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings with all hydroxy groups on non-condensed rings, e.g. phenylphenol
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
LA INVENCION SE REFIERE A COMPUESTOS DE FORMULA (I), EN LA CUAL: (X) REPRESENTA LOS CARBOCICLOS AROMATICOS SIGUIENTES: (A) O (B), DONDE R 1 , R 2 , R 3 , R 4 , R 5 , R 6 Y R 7 SON TAL COMO SE DEFINEN EN LA DESCRIPCION, ASI COMO A SUS SALES, EL PROCEDIMIENTO Y LOS INTERMEDIARIOS PARA SU PREPARACION, SU APLICACION COMO MEDICAMENTO Y LAS COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9601212A FR2744444B1 (fr) | 1996-02-01 | 1996-02-01 | Nouveaux composes biphenyles, procede et intermediaires de preparation, application a titre de medicaments et compositions pharmaceutiques les renfermant |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2175337T3 true ES2175337T3 (es) | 2002-11-16 |
Family
ID=9488725
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES97902408T Expired - Lifetime ES2175337T3 (es) | 1996-02-01 | 1997-01-30 | Compuesto bifenilicos y su utilizacion como agentes estrogenicos. |
Country Status (10)
Country | Link |
---|---|
US (2) | US6147119A (es) |
EP (1) | EP0880496B1 (es) |
JP (1) | JP4143122B2 (es) |
AT (1) | ATE218122T1 (es) |
DE (1) | DE69712868T2 (es) |
DK (1) | DK0880496T3 (es) |
ES (1) | ES2175337T3 (es) |
FR (1) | FR2744444B1 (es) |
PT (1) | PT880496E (es) |
WO (1) | WO1997028116A1 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI306450B (en) * | 2001-12-13 | 2009-02-21 | Wyeth Corp | Substituted phenyl naphthalenes as estrogenic agents |
AU2005323242A1 (en) * | 2004-12-31 | 2006-07-13 | Aventis Pharmaceuticals Inc. | Use of selected compounds for protection of neurones and oligodendrocytes in the treatment of multiple sclerosis |
CA2593097A1 (en) * | 2004-12-31 | 2006-07-13 | Aventis Pharmaceuticals Inc. | Use of certain phenyl-naphthyl compounds that do not have significant affintiy to er alpha or beta for protection of neurons and oligodendrocytes in the treatment of multiple sclerosis |
JP2008526744A (ja) * | 2005-01-04 | 2008-07-24 | アベンティス・ファーマスーティカルズ・インコーポレイテツド | 多発性硬化症(ms)の治療における神経細胞及び乏突起膠細胞を保護するための或る種のフェニルナフチル化合物の使用 |
JP4590637B2 (ja) * | 2006-02-16 | 2010-12-01 | 国立大学法人 千葉大学 | ベンゼン誘導体の製造方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0532579A (ja) * | 1991-08-01 | 1993-02-09 | Banyu Pharmaceut Co Ltd | エストロゲン物質be−25327及びその製造法 |
-
1996
- 1996-02-01 FR FR9601212A patent/FR2744444B1/fr not_active Expired - Fee Related
-
1997
- 1997-01-30 PT PT97902408T patent/PT880496E/pt unknown
- 1997-01-30 WO PCT/FR1997/000184 patent/WO1997028116A1/fr active IP Right Grant
- 1997-01-30 EP EP97902408A patent/EP0880496B1/fr not_active Expired - Lifetime
- 1997-01-30 AT AT97902408T patent/ATE218122T1/de not_active IP Right Cessation
- 1997-01-30 US US09/117,634 patent/US6147119A/en not_active Expired - Lifetime
- 1997-01-30 ES ES97902408T patent/ES2175337T3/es not_active Expired - Lifetime
- 1997-01-30 DK DK97902408T patent/DK0880496T3/da active
- 1997-01-30 DE DE69712868T patent/DE69712868T2/de not_active Expired - Lifetime
- 1997-01-30 JP JP52736697A patent/JP4143122B2/ja not_active Expired - Fee Related
-
2000
- 2000-07-27 US US09/627,023 patent/US6365775B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
FR2744444A1 (fr) | 1997-08-08 |
DE69712868T2 (de) | 2002-11-28 |
JP4143122B2 (ja) | 2008-09-03 |
DK0880496T3 (da) | 2002-09-09 |
US6365775B1 (en) | 2002-04-02 |
DE69712868D1 (de) | 2002-07-04 |
EP0880496A1 (fr) | 1998-12-02 |
ATE218122T1 (de) | 2002-06-15 |
EP0880496B1 (fr) | 2002-05-29 |
PT880496E (pt) | 2002-10-31 |
US6147119A (en) | 2000-11-14 |
JP2000504003A (ja) | 2000-04-04 |
FR2744444B1 (fr) | 1998-05-29 |
WO1997028116A1 (fr) | 1997-08-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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