PT880496E - Compostos bifenilos e sua utilizacao como agentes estrogenicos - Google Patents
Compostos bifenilos e sua utilizacao como agentes estrogenicosInfo
- Publication number
- PT880496E PT880496E PT97902408T PT97902408T PT880496E PT 880496 E PT880496 E PT 880496E PT 97902408 T PT97902408 T PT 97902408T PT 97902408 T PT97902408 T PT 97902408T PT 880496 E PT880496 E PT 880496E
- Authority
- PT
- Portugal
- Prior art keywords
- pct
- biphenyl compounds
- estrogenic agents
- sec
- date
- Prior art date
Links
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N diphenyl Chemical class C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 title 1
- 239000000262 estrogen Substances 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/24—Halogenated derivatives
- C07C39/38—Halogenated derivatives with at least one hydroxy group on a condensed ring system containing two rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
- C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
- C07C217/20—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
- C07C39/15—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings with all hydroxy groups on non-condensed rings, e.g. phenylphenol
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9601212A FR2744444B1 (fr) | 1996-02-01 | 1996-02-01 | Nouveaux composes biphenyles, procede et intermediaires de preparation, application a titre de medicaments et compositions pharmaceutiques les renfermant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT880496E true PT880496E (pt) | 2002-10-31 |
Family
ID=9488725
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT97902408T PT880496E (pt) | 1996-02-01 | 1997-01-30 | Compostos bifenilos e sua utilizacao como agentes estrogenicos |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6147119A (pt) |
| EP (1) | EP0880496B1 (pt) |
| JP (1) | JP4143122B2 (pt) |
| AT (1) | ATE218122T1 (pt) |
| DE (1) | DE69712868T2 (pt) |
| DK (1) | DK0880496T3 (pt) |
| ES (1) | ES2175337T3 (pt) |
| FR (1) | FR2744444B1 (pt) |
| PT (1) | PT880496E (pt) |
| WO (1) | WO1997028116A1 (pt) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6914074B2 (en) * | 2001-12-13 | 2005-07-05 | Wyeth | Substituted phenyl naphthalenes as estrogenic agents |
| RU2007129150A (ru) * | 2004-12-31 | 2009-02-10 | Авентис Фармасьютикалз Инк. (Us) | Применение ряда фенилнафтильных соединений, которые не проявляют значительной аффинности в отношениях эстрогеновых рецепторов (er) |
| AU2005323242A1 (en) * | 2004-12-31 | 2006-07-13 | Aventis Pharmaceuticals Inc. | Use of selected compounds for protection of neurones and oligodendrocytes in the treatment of multiple sclerosis |
| AU2005323163A1 (en) * | 2005-01-04 | 2006-07-13 | Aventis Pharmaceuticals Inc. | Use of certain phenyl napthyl compounds for protection of neurons and oligodendrocytes in the treatment of multiple sclerosis (MS) |
| JP4590637B2 (ja) * | 2006-02-16 | 2010-12-01 | 国立大学法人 千葉大学 | ベンゼン誘導体の製造方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0532579A (ja) * | 1991-08-01 | 1993-02-09 | Banyu Pharmaceut Co Ltd | エストロゲン物質ｂｅ−２５３２７及びその製造法 |
-
1996
- 1996-02-01 FR FR9601212A patent/FR2744444B1/fr not_active Expired - Fee Related
-
1997
- 1997-01-30 ES ES97902408T patent/ES2175337T3/es not_active Expired - Lifetime
- 1997-01-30 AT AT97902408T patent/ATE218122T1/de not_active IP Right Cessation
- 1997-01-30 DE DE69712868T patent/DE69712868T2/de not_active Expired - Lifetime
- 1997-01-30 DK DK97902408T patent/DK0880496T3/da active
- 1997-01-30 JP JP52736697A patent/JP4143122B2/ja not_active Expired - Fee Related
- 1997-01-30 EP EP97902408A patent/EP0880496B1/fr not_active Expired - Lifetime
- 1997-01-30 PT PT97902408T patent/PT880496E/pt unknown
- 1997-01-30 WO PCT/FR1997/000184 patent/WO1997028116A1/fr not_active Ceased
- 1997-01-30 US US09/117,634 patent/US6147119A/en not_active Expired - Lifetime
-
2000
- 2000-07-27 US US09/627,023 patent/US6365775B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| FR2744444A1 (fr) | 1997-08-08 |
| ATE218122T1 (de) | 2002-06-15 |
| ES2175337T3 (es) | 2002-11-16 |
| JP2000504003A (ja) | 2000-04-04 |
| EP0880496A1 (fr) | 1998-12-02 |
| JP4143122B2 (ja) | 2008-09-03 |
| WO1997028116A1 (fr) | 1997-08-07 |
| DE69712868T2 (de) | 2002-11-28 |
| DE69712868D1 (de) | 2002-07-04 |
| US6147119A (en) | 2000-11-14 |
| FR2744444B1 (fr) | 1998-05-29 |
| EP0880496B1 (fr) | 2002-05-29 |
| US6365775B1 (en) | 2002-04-02 |
| DK0880496T3 (da) | 2002-09-09 |
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