BR0015177A - ésteres de ácido benzóico de oxazolidinonas possuindo um substituinte hidroxiacetilpiperazina - Google Patents

ésteres de ácido benzóico de oxazolidinonas possuindo um substituinte hidroxiacetilpiperazina

Info

Publication number
BR0015177A
BR0015177A BR0015177-7A BR0015177A BR0015177A BR 0015177 A BR0015177 A BR 0015177A BR 0015177 A BR0015177 A BR 0015177A BR 0015177 A BR0015177 A BR 0015177A
Authority
BR
Brazil
Prior art keywords
oxazolidinones
benzoic acid
acid esters
hydroxyacetylpiperazine
substituent
Prior art date
Application number
BR0015177-7A
Other languages
English (en)
Inventor
Jackson B Hester Jr
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of BR0015177A publication Critical patent/BR0015177A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Abstract

"éSTERES DE áCIDO BENZóICO DE OXAZOLIDINONAS POSSUINDO UM SUBSTITUINTE HIDROXIACETILPIPERAZINA". A presente invenção provê um composto da fórmula I, que possui atividade potente contra bactérias grampositivas e gram-negativas.
BR0015177-7A 1999-12-14 2000-12-06 ésteres de ácido benzóico de oxazolidinonas possuindo um substituinte hidroxiacetilpiperazina BR0015177A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17067599P 1999-12-14 1999-12-14
PCT/US2000/032432 WO2001044212A1 (en) 1999-12-14 2000-12-06 Benzoic acid esters of oxazolidinones having a hydroxyacetylpiperazine substituent

Publications (1)

Publication Number Publication Date
BR0015177A true BR0015177A (pt) 2002-06-18

Family

ID=22620832

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0015177-7A BR0015177A (pt) 1999-12-14 2000-12-06 ésteres de ácido benzóico de oxazolidinonas possuindo um substituinte hidroxiacetilpiperazina

Country Status (26)

Country Link
US (1) US6281210B1 (pt)
EP (1) EP1242395B1 (pt)
JP (1) JP2003516977A (pt)
KR (1) KR20020062332A (pt)
CN (1) CN1390211A (pt)
AR (1) AR026547A1 (pt)
AT (1) ATE288423T1 (pt)
AU (1) AU1805801A (pt)
BR (1) BR0015177A (pt)
CA (1) CA2387047A1 (pt)
CO (1) CO5261527A1 (pt)
CZ (1) CZ20022389A3 (pt)
DE (1) DE60017941T2 (pt)
EA (1) EA200200673A1 (pt)
ES (1) ES2236006T3 (pt)
HU (1) HUP0203787A3 (pt)
IL (1) IL150031A0 (pt)
MX (1) MXPA02005909A (pt)
NO (1) NO20022811D0 (pt)
PE (1) PE20010851A1 (pt)
PL (1) PL355369A1 (pt)
PT (1) PT1242395E (pt)
SK (1) SK5972002A3 (pt)
TW (1) TW544449B (pt)
WO (1) WO2001044212A1 (pt)
ZA (1) ZA200202953B (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19962924A1 (de) 1999-12-24 2001-07-05 Bayer Ag Substituierte Oxazolidinone und ihre Verwendung
ATE321024T1 (de) * 2000-10-17 2006-04-15 Pharmacia & Upjohn Co Llc Verfahren zur herstellung von oxazolidinonverbindungen
DE10129725A1 (de) 2001-06-20 2003-01-02 Bayer Ag Kombinationstherapie substituierter Oxazolidinone
TW200404069A (en) * 2002-06-28 2004-03-16 Upjohn Co Difluorothioacetamides of oxazolidinones with a glycoloylpiperazine substituent
TW200403240A (en) * 2002-06-28 2004-03-01 Upjohn Co Difluorothioacetamides of oxazolidinones as antibacterial agents
ES2271660T3 (es) * 2002-11-21 2007-04-16 PHARMACIA & UPJOHN COMPANY LLC Derivados de n-(4-piperazin-1-il)-fenil-2-oxazolidinona-5-carboxamida y compuestos relacionados como agentes antibacterianos.
DE10300111A1 (de) * 2003-01-07 2004-07-15 Bayer Healthcare Ag Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid
DE10355461A1 (de) 2003-11-27 2005-06-23 Bayer Healthcare Ag Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung
DE102004062475A1 (de) * 2004-12-24 2006-07-06 Bayer Healthcare Ag Feste, oral applizierbare pharmazeutische Darreichungsformen mit modifizierter Freisetzung
EP1685841A1 (en) 2005-01-31 2006-08-02 Bayer Health Care Aktiengesellschaft Prevention and treatment of thromboembolic disorders
DE102005045518A1 (de) * 2005-09-23 2007-03-29 Bayer Healthcare Ag 2-Aminoethoxyessigsäure-Derivate und ihre Verwendung
PL1934208T3 (pl) 2005-10-04 2011-09-30 Bayer Ip Gmbh Nowa polimorficzna postać 5-chloro-N-({ (5S)-2-okso-3-[4-( 3-okso-4-morfolinylo)-fenylo]-1,3-oksazolidyn-5-ylo}-metylo)-2-tiofenokarboksamidu
DE102005047561A1 (de) 2005-10-04 2007-04-05 Bayer Healthcare Ag Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung
WO2008073444A2 (en) * 2006-12-12 2008-06-19 The Johns Hopkins University Phou (perf), a persistence switch involved in persister formation as a drug target for persister bacteria
EP2170874A4 (en) * 2007-06-22 2011-08-31 Orchid Res Lab Ltd NEW COMPOUNDS AND THEIR USE

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3698724B2 (ja) * 1993-11-22 2005-09-21 ファルマシア・アンド・アップジョン・カンパニー 置換−ヒドロキシアセチルピペラジンフェニルオキサゾリジノンのエステル
MY116093A (en) * 1996-02-26 2003-11-28 Upjohn Co Azolyl piperazinyl phenyl oxazolidinone antimicrobials
EP0984947B8 (en) * 1997-05-30 2005-06-15 Pharmacia & Upjohn Company LLC Oxazolidinone antibacterial agents having a thiocarbonyl functionality
GB9812019D0 (en) * 1998-06-05 1998-07-29 Zeneca Ltd Chemical compounds

Also Published As

Publication number Publication date
CO5261527A1 (es) 2003-03-31
DE60017941D1 (de) 2005-03-10
EP1242395B1 (en) 2005-02-02
PL355369A1 (en) 2004-04-19
PE20010851A1 (es) 2001-08-17
TW544449B (en) 2003-08-01
AR026547A1 (es) 2003-02-19
EP1242395A1 (en) 2002-09-25
CN1390211A (zh) 2003-01-08
NO20022811L (no) 2002-06-13
ZA200202953B (en) 2003-09-23
MXPA02005909A (es) 2002-10-23
HUP0203787A2 (hu) 2003-07-28
WO2001044212A1 (en) 2001-06-21
AU1805801A (en) 2001-06-25
NO20022811D0 (no) 2002-06-13
ES2236006T3 (es) 2005-07-16
CA2387047A1 (en) 2001-06-21
HUP0203787A3 (en) 2005-06-28
KR20020062332A (ko) 2002-07-25
US6281210B1 (en) 2001-08-28
SK5972002A3 (en) 2003-01-09
ATE288423T1 (de) 2005-02-15
DE60017941T2 (de) 2006-03-30
CZ20022389A3 (cs) 2002-10-16
PT1242395E (pt) 2005-05-31
EA200200673A1 (ru) 2002-12-26
IL150031A0 (en) 2002-12-01
JP2003516977A (ja) 2003-05-20

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2008 DE 30/06/2009.