HUP0203787A3 - Benzoic acid esters of oxazolidinones having a hydroxyacetylpiperazine substituent, pharmaceutical compositions containing them and their use - Google Patents
Benzoic acid esters of oxazolidinones having a hydroxyacetylpiperazine substituent, pharmaceutical compositions containing them and their useInfo
- Publication number
- HUP0203787A3 HUP0203787A3 HU0203787A HUP0203787A HUP0203787A3 HU P0203787 A3 HUP0203787 A3 HU P0203787A3 HU 0203787 A HU0203787 A HU 0203787A HU P0203787 A HUP0203787 A HU P0203787A HU P0203787 A3 HUP0203787 A3 HU P0203787A3
- Authority
- HU
- Hungary
- Prior art keywords
- oxazolidinones
- pharmaceutical compositions
- benzoic acid
- acid esters
- compositions containing
- Prior art date
Links
- IZXIZTKNFFYFOF-UHFFFAOYSA-N 2-Oxazolidone Chemical class O=C1NCCO1 IZXIZTKNFFYFOF-UHFFFAOYSA-N 0.000 title 1
- YKZWLZLFBNIZCC-UHFFFAOYSA-N 2-hydroxy-1-piperazin-1-ylethanone Chemical group OCC(=O)N1CCNCC1 YKZWLZLFBNIZCC-UHFFFAOYSA-N 0.000 title 1
- 150000001558 benzoic acid derivatives Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17067599P | 1999-12-14 | 1999-12-14 | |
| PCT/US2000/032432 WO2001044212A1 (en) | 1999-12-14 | 2000-12-06 | Benzoic acid esters of oxazolidinones having a hydroxyacetylpiperazine substituent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0203787A2 HUP0203787A2 (hu) | 2003-07-28 |
| HUP0203787A3 true HUP0203787A3 (en) | 2005-06-28 |
Family
ID=22620832
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0203787A HUP0203787A3 (en) | 1999-12-14 | 2000-12-06 | Benzoic acid esters of oxazolidinones having a hydroxyacetylpiperazine substituent, pharmaceutical compositions containing them and their use |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US6281210B1 (hu) |
| EP (1) | EP1242395B1 (hu) |
| JP (1) | JP2003516977A (hu) |
| KR (1) | KR20020062332A (hu) |
| CN (1) | CN1390211A (hu) |
| AR (1) | AR026547A1 (hu) |
| AT (1) | ATE288423T1 (hu) |
| AU (1) | AU1805801A (hu) |
| BR (1) | BR0015177A (hu) |
| CA (1) | CA2387047A1 (hu) |
| CO (1) | CO5261527A1 (hu) |
| CZ (1) | CZ20022389A3 (hu) |
| DE (1) | DE60017941T2 (hu) |
| EA (1) | EA200200673A1 (hu) |
| ES (1) | ES2236006T3 (hu) |
| HU (1) | HUP0203787A3 (hu) |
| IL (1) | IL150031A0 (hu) |
| MX (1) | MXPA02005909A (hu) |
| NO (1) | NO20022811L (hu) |
| PE (1) | PE20010851A1 (hu) |
| PL (1) | PL355369A1 (hu) |
| PT (1) | PT1242395E (hu) |
| SK (1) | SK5972002A3 (hu) |
| TW (1) | TW544449B (hu) |
| WO (1) | WO2001044212A1 (hu) |
| ZA (1) | ZA200202953B (hu) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19962924A1 (de) | 1999-12-24 | 2001-07-05 | Bayer Ag | Substituierte Oxazolidinone und ihre Verwendung |
| ATE321024T1 (de) * | 2000-10-17 | 2006-04-15 | Pharmacia & Upjohn Co Llc | Verfahren zur herstellung von oxazolidinonverbindungen |
| DE10129725A1 (de) | 2001-06-20 | 2003-01-02 | Bayer Ag | Kombinationstherapie substituierter Oxazolidinone |
| TW200403240A (en) * | 2002-06-28 | 2004-03-01 | Upjohn Co | Difluorothioacetamides of oxazolidinones as antibacterial agents |
| TW200404069A (en) * | 2002-06-28 | 2004-03-16 | Upjohn Co | Difluorothioacetamides of oxazolidinones with a glycoloylpiperazine substituent |
| BR0316483A (pt) | 2002-11-21 | 2005-10-11 | Upjohn Co | Derivados de n-(4-(piperazin-1-il)-fenil-2-oxazolidinona-5-carboxami da e compostos relacionados como agentes antibacterianos |
| DE10300111A1 (de) * | 2003-01-07 | 2004-07-15 | Bayer Healthcare Ag | Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid |
| DE10355461A1 (de) | 2003-11-27 | 2005-06-23 | Bayer Healthcare Ag | Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung |
| DE102004062475A1 (de) * | 2004-12-24 | 2006-07-06 | Bayer Healthcare Ag | Feste, oral applizierbare pharmazeutische Darreichungsformen mit modifizierter Freisetzung |
| EP1685841A1 (en) * | 2005-01-31 | 2006-08-02 | Bayer Health Care Aktiengesellschaft | Prevention and treatment of thromboembolic disorders |
| DE102005045518A1 (de) * | 2005-09-23 | 2007-03-29 | Bayer Healthcare Ag | 2-Aminoethoxyessigsäure-Derivate und ihre Verwendung |
| DE102005047561A1 (de) | 2005-10-04 | 2007-04-05 | Bayer Healthcare Ag | Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung |
| CA2624310C (en) | 2005-10-04 | 2014-01-07 | Bayer Healthcare Ag | Polymorphic form of 5-chloro-n-({5s)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophenecarboxamide |
| US20100210602A1 (en) * | 2006-12-12 | 2010-08-19 | The Johns Hopkins University | PhoU (PerF), A PERSISTENCE SWITCH INVOLVED IN PERSISTER FORMATION AND TOLERANCE TO MULTIPLE ANTIBIOTICS AND STRESSES AS A DRUG TARGET FOR PERSISTER BACTERIA |
| EP2170874A4 (en) * | 2007-06-22 | 2011-08-31 | Orchid Res Lab Ltd | NEW COMPOUNDS AND THEIR USE |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0730591T3 (da) * | 1993-11-22 | 2000-01-31 | Upjohn Co | Estere af substituerede hydroxyacetyl-piperazin-phenyl-oxazolidinoner |
| MY116093A (en) * | 1996-02-26 | 2003-11-28 | Upjohn Co | Azolyl piperazinyl phenyl oxazolidinone antimicrobials |
| US6218413B1 (en) * | 1997-05-30 | 2001-04-17 | Pharmacia & Upjohn Company | Oxazolidinone antibacterial agents having a thiocarbonyl functionality |
| GB9812019D0 (en) * | 1998-06-05 | 1998-07-29 | Zeneca Ltd | Chemical compounds |
-
2000
- 2000-11-15 PE PE2000001220A patent/PE20010851A1/es not_active Application Discontinuation
- 2000-11-20 AR ARP000106119A patent/AR026547A1/es unknown
- 2000-11-24 TW TW089125030A patent/TW544449B/zh not_active IP Right Cessation
- 2000-12-06 HU HU0203787A patent/HUP0203787A3/hu unknown
- 2000-12-06 MX MXPA02005909A patent/MXPA02005909A/es not_active Application Discontinuation
- 2000-12-06 AU AU18058/01A patent/AU1805801A/en not_active Abandoned
- 2000-12-06 DE DE60017941T patent/DE60017941T2/de not_active Expired - Fee Related
- 2000-12-06 BR BR0015177-7A patent/BR0015177A/pt not_active IP Right Cessation
- 2000-12-06 JP JP2001544702A patent/JP2003516977A/ja active Pending
- 2000-12-06 CZ CZ20022389A patent/CZ20022389A3/cs unknown
- 2000-12-06 IL IL15003100A patent/IL150031A0/xx unknown
- 2000-12-06 CN CN00815710A patent/CN1390211A/zh active Pending
- 2000-12-06 ES ES00980849T patent/ES2236006T3/es not_active Expired - Lifetime
- 2000-12-06 WO PCT/US2000/032432 patent/WO2001044212A1/en active IP Right Grant
- 2000-12-06 SK SK597-2002A patent/SK5972002A3/sk unknown
- 2000-12-06 CA CA002387047A patent/CA2387047A1/en not_active Abandoned
- 2000-12-06 EA EA200200673A patent/EA200200673A1/ru unknown
- 2000-12-06 KR KR1020027007514A patent/KR20020062332A/ko not_active Application Discontinuation
- 2000-12-06 PL PL00355369A patent/PL355369A1/xx not_active Application Discontinuation
- 2000-12-06 US US09/732,088 patent/US6281210B1/en not_active Expired - Fee Related
- 2000-12-06 EP EP00980849A patent/EP1242395B1/en not_active Expired - Lifetime
- 2000-12-06 PT PT00980849T patent/PT1242395E/pt unknown
- 2000-12-06 AT AT00980849T patent/ATE288423T1/de not_active IP Right Cessation
- 2000-12-12 CO CO00094338A patent/CO5261527A1/es not_active Application Discontinuation
-
2002
- 2002-04-15 ZA ZA200202953A patent/ZA200202953B/xx unknown
- 2002-06-13 NO NO20022811A patent/NO20022811L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US6281210B1 (en) | 2001-08-28 |
| SK5972002A3 (en) | 2003-01-09 |
| WO2001044212A1 (en) | 2001-06-21 |
| NO20022811D0 (no) | 2002-06-13 |
| TW544449B (en) | 2003-08-01 |
| CO5261527A1 (es) | 2003-03-31 |
| IL150031A0 (en) | 2002-12-01 |
| HUP0203787A2 (hu) | 2003-07-28 |
| JP2003516977A (ja) | 2003-05-20 |
| AR026547A1 (es) | 2003-02-19 |
| ES2236006T3 (es) | 2005-07-16 |
| BR0015177A (pt) | 2002-06-18 |
| EA200200673A1 (ru) | 2002-12-26 |
| PL355369A1 (en) | 2004-04-19 |
| KR20020062332A (ko) | 2002-07-25 |
| ATE288423T1 (de) | 2005-02-15 |
| CZ20022389A3 (cs) | 2002-10-16 |
| MXPA02005909A (es) | 2002-10-23 |
| PT1242395E (pt) | 2005-05-31 |
| ZA200202953B (en) | 2003-09-23 |
| CA2387047A1 (en) | 2001-06-21 |
| PE20010851A1 (es) | 2001-08-17 |
| DE60017941T2 (de) | 2006-03-30 |
| AU1805801A (en) | 2001-06-25 |
| CN1390211A (zh) | 2003-01-08 |
| EP1242395A1 (en) | 2002-09-25 |
| NO20022811L (no) | 2002-06-13 |
| DE60017941D1 (de) | 2005-03-10 |
| EP1242395B1 (en) | 2005-02-02 |
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