AR026547A1 - Esteres del acido benzoico de oxazolidinonas que tienen un substituyente hidroxiacetilpiperazina - Google Patents

Esteres del acido benzoico de oxazolidinonas que tienen un substituyente hidroxiacetilpiperazina

Info

Publication number
AR026547A1
AR026547A1 ARP000106119A ARP000106119A AR026547A1 AR 026547 A1 AR026547 A1 AR 026547A1 AR P000106119 A ARP000106119 A AR P000106119A AR P000106119 A ARP000106119 A AR P000106119A AR 026547 A1 AR026547 A1 AR 026547A1
Authority
AR
Argentina
Prior art keywords
hydroxiacetilepiperazine
esteres
oxazolidinones
substituent
benzoic acid
Prior art date
Application number
ARP000106119A
Other languages
English (en)
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of AR026547A1 publication Critical patent/AR026547A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente provee un compuesto de formula (1) que tiene potente actividad contra bacterias grampositivas y gramnegativas. Los valores de los sustituyentesson como se definen en la descripcion.
ARP000106119A 1999-12-14 2000-11-20 Esteres del acido benzoico de oxazolidinonas que tienen un substituyente hidroxiacetilpiperazina AR026547A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17067599P 1999-12-14 1999-12-14

Publications (1)

Publication Number Publication Date
AR026547A1 true AR026547A1 (es) 2003-02-19

Family

ID=22620832

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000106119A AR026547A1 (es) 1999-12-14 2000-11-20 Esteres del acido benzoico de oxazolidinonas que tienen un substituyente hidroxiacetilpiperazina

Country Status (26)

Country Link
US (1) US6281210B1 (es)
EP (1) EP1242395B1 (es)
JP (1) JP2003516977A (es)
KR (1) KR20020062332A (es)
CN (1) CN1390211A (es)
AR (1) AR026547A1 (es)
AT (1) ATE288423T1 (es)
AU (1) AU1805801A (es)
BR (1) BR0015177A (es)
CA (1) CA2387047A1 (es)
CO (1) CO5261527A1 (es)
CZ (1) CZ20022389A3 (es)
DE (1) DE60017941T2 (es)
EA (1) EA200200673A1 (es)
ES (1) ES2236006T3 (es)
HU (1) HUP0203787A3 (es)
IL (1) IL150031A0 (es)
MX (1) MXPA02005909A (es)
NO (1) NO20022811D0 (es)
PE (1) PE20010851A1 (es)
PL (1) PL355369A1 (es)
PT (1) PT1242395E (es)
SK (1) SK5972002A3 (es)
TW (1) TW544449B (es)
WO (1) WO2001044212A1 (es)
ZA (1) ZA200202953B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19962924A1 (de) 1999-12-24 2001-07-05 Bayer Ag Substituierte Oxazolidinone und ihre Verwendung
DE60118241T2 (de) 2000-10-17 2006-12-28 Pharmacia & Upjohn Co. Llc, Kalamazoo Verfahren zur herstellung von oxazolidinonverbindungen
DE10129725A1 (de) 2001-06-20 2003-01-02 Bayer Ag Kombinationstherapie substituierter Oxazolidinone
TW200403240A (en) * 2002-06-28 2004-03-01 Upjohn Co Difluorothioacetamides of oxazolidinones as antibacterial agents
TW200404069A (en) * 2002-06-28 2004-03-16 Upjohn Co Difluorothioacetamides of oxazolidinones with a glycoloylpiperazine substituent
AR042086A1 (es) * 2002-11-21 2005-06-08 Upjohn Co N-aril-2- oxazolidinon -5- carboxamidas y sus derivados, usados como agentes antibacterianos
DE10300111A1 (de) * 2003-01-07 2004-07-15 Bayer Healthcare Ag Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid
DE10355461A1 (de) 2003-11-27 2005-06-23 Bayer Healthcare Ag Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung
DE102004062475A1 (de) * 2004-12-24 2006-07-06 Bayer Healthcare Ag Feste, oral applizierbare pharmazeutische Darreichungsformen mit modifizierter Freisetzung
EP1685841A1 (en) 2005-01-31 2006-08-02 Bayer Health Care Aktiengesellschaft Prevention and treatment of thromboembolic disorders
DE102005045518A1 (de) * 2005-09-23 2007-03-29 Bayer Healthcare Ag 2-Aminoethoxyessigsäure-Derivate und ihre Verwendung
DE102005047561A1 (de) 2005-10-04 2007-04-05 Bayer Healthcare Ag Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung
DE502006009169D1 (en) 2005-10-04 2011-05-05 Bayer Schering Pharma Ag NEUE POLYMORPHE FORM VON 5-CHLOR-N-(ä ( 5S )-2-0X0-3-Ä4-( 3-OXO-4-MORPHOLINYL)-PHENYLÜ-1,3-OXAZOLIDIN-5-YLü -METHYL)-2-THIOPHENCARBOXAMID
WO2008073444A2 (en) * 2006-12-12 2008-06-19 The Johns Hopkins University Phou (perf), a persistence switch involved in persister formation as a drug target for persister bacteria
WO2009001192A2 (en) * 2007-06-22 2008-12-31 Orchid Research Laboratories Limited Novel compounds and their use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0730591B1 (en) * 1993-11-22 1999-07-14 PHARMACIA & UPJOHN COMPANY Esters of substituted-hydroxyacetyl piperazine phenyl oxazolidinones
MY116093A (en) * 1996-02-26 2003-11-28 Upjohn Co Azolyl piperazinyl phenyl oxazolidinone antimicrobials
US6218413B1 (en) * 1997-05-30 2001-04-17 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
GB9812019D0 (en) * 1998-06-05 1998-07-29 Zeneca Ltd Chemical compounds

Also Published As

Publication number Publication date
BR0015177A (pt) 2002-06-18
EA200200673A1 (ru) 2002-12-26
HUP0203787A3 (en) 2005-06-28
DE60017941D1 (de) 2005-03-10
CZ20022389A3 (cs) 2002-10-16
HUP0203787A2 (hu) 2003-07-28
NO20022811L (no) 2002-06-13
CN1390211A (zh) 2003-01-08
WO2001044212A1 (en) 2001-06-21
CA2387047A1 (en) 2001-06-21
ZA200202953B (en) 2003-09-23
JP2003516977A (ja) 2003-05-20
IL150031A0 (en) 2002-12-01
KR20020062332A (ko) 2002-07-25
EP1242395B1 (en) 2005-02-02
SK5972002A3 (en) 2003-01-09
ATE288423T1 (de) 2005-02-15
PE20010851A1 (es) 2001-08-17
EP1242395A1 (en) 2002-09-25
NO20022811D0 (no) 2002-06-13
DE60017941T2 (de) 2006-03-30
PL355369A1 (en) 2004-04-19
TW544449B (en) 2003-08-01
US6281210B1 (en) 2001-08-28
ES2236006T3 (es) 2005-07-16
AU1805801A (en) 2001-06-25
PT1242395E (pt) 2005-05-31
MXPA02005909A (es) 2002-10-23
CO5261527A1 (es) 2003-03-31

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