IL150031A0 - Benzoic acid esters of oxazolidines having a hydroxyacetylpiperazine substituent - Google Patents

Benzoic acid esters of oxazolidines having a hydroxyacetylpiperazine substituent

Info

Publication number
IL150031A0
IL150031A0 IL15003100A IL15003100A IL150031A0 IL 150031 A0 IL150031 A0 IL 150031A0 IL 15003100 A IL15003100 A IL 15003100A IL 15003100 A IL15003100 A IL 15003100A IL 150031 A0 IL150031 A0 IL 150031A0
Authority
IL
Israel
Prior art keywords
oxazolidines
benzoic acid
acid esters
hydroxyacetylpiperazine
substituent
Prior art date
Application number
IL15003100A
Other languages
English (en)
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of IL150031A0 publication Critical patent/IL150031A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL15003100A 1999-12-14 2000-12-06 Benzoic acid esters of oxazolidines having a hydroxyacetylpiperazine substituent IL150031A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17067599P 1999-12-14 1999-12-14
PCT/US2000/032432 WO2001044212A1 (en) 1999-12-14 2000-12-06 Benzoic acid esters of oxazolidinones having a hydroxyacetylpiperazine substituent

Publications (1)

Publication Number Publication Date
IL150031A0 true IL150031A0 (en) 2002-12-01

Family

ID=22620832

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15003100A IL150031A0 (en) 1999-12-14 2000-12-06 Benzoic acid esters of oxazolidines having a hydroxyacetylpiperazine substituent

Country Status (26)

Country Link
US (1) US6281210B1 (xx)
EP (1) EP1242395B1 (xx)
JP (1) JP2003516977A (xx)
KR (1) KR20020062332A (xx)
CN (1) CN1390211A (xx)
AR (1) AR026547A1 (xx)
AT (1) ATE288423T1 (xx)
AU (1) AU1805801A (xx)
BR (1) BR0015177A (xx)
CA (1) CA2387047A1 (xx)
CO (1) CO5261527A1 (xx)
CZ (1) CZ20022389A3 (xx)
DE (1) DE60017941T2 (xx)
EA (1) EA200200673A1 (xx)
ES (1) ES2236006T3 (xx)
HU (1) HUP0203787A3 (xx)
IL (1) IL150031A0 (xx)
MX (1) MXPA02005909A (xx)
NO (1) NO20022811L (xx)
PE (1) PE20010851A1 (xx)
PL (1) PL355369A1 (xx)
PT (1) PT1242395E (xx)
SK (1) SK5972002A3 (xx)
TW (1) TW544449B (xx)
WO (1) WO2001044212A1 (xx)
ZA (1) ZA200202953B (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19962924A1 (de) 1999-12-24 2001-07-05 Bayer Ag Substituierte Oxazolidinone und ihre Verwendung
ATE321024T1 (de) * 2000-10-17 2006-04-15 Pharmacia & Upjohn Co Llc Verfahren zur herstellung von oxazolidinonverbindungen
DE10129725A1 (de) 2001-06-20 2003-01-02 Bayer Ag Kombinationstherapie substituierter Oxazolidinone
TW200403240A (en) * 2002-06-28 2004-03-01 Upjohn Co Difluorothioacetamides of oxazolidinones as antibacterial agents
TW200404069A (en) * 2002-06-28 2004-03-16 Upjohn Co Difluorothioacetamides of oxazolidinones with a glycoloylpiperazine substituent
BR0316483A (pt) 2002-11-21 2005-10-11 Upjohn Co Derivados de n-(4-(piperazin-1-il)-fenil-2-oxazolidinona-5-carboxami da e compostos relacionados como agentes antibacterianos
DE10300111A1 (de) * 2003-01-07 2004-07-15 Bayer Healthcare Ag Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid
DE10355461A1 (de) 2003-11-27 2005-06-23 Bayer Healthcare Ag Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung
DE102004062475A1 (de) * 2004-12-24 2006-07-06 Bayer Healthcare Ag Feste, oral applizierbare pharmazeutische Darreichungsformen mit modifizierter Freisetzung
EP1685841A1 (en) * 2005-01-31 2006-08-02 Bayer Health Care Aktiengesellschaft Prevention and treatment of thromboembolic disorders
DE102005045518A1 (de) * 2005-09-23 2007-03-29 Bayer Healthcare Ag 2-Aminoethoxyessigsäure-Derivate und ihre Verwendung
DE102005047561A1 (de) 2005-10-04 2007-04-05 Bayer Healthcare Ag Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung
CA2624310C (en) 2005-10-04 2014-01-07 Bayer Healthcare Ag Polymorphic form of 5-chloro-n-({5s)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophenecarboxamide
US20100210602A1 (en) * 2006-12-12 2010-08-19 The Johns Hopkins University PhoU (PerF), A PERSISTENCE SWITCH INVOLVED IN PERSISTER FORMATION AND TOLERANCE TO MULTIPLE ANTIBIOTICS AND STRESSES AS A DRUG TARGET FOR PERSISTER BACTERIA
EP2170874A4 (en) * 2007-06-22 2011-08-31 Orchid Res Lab Ltd NEW COMPOUNDS AND THEIR USE

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0730591T3 (da) * 1993-11-22 2000-01-31 Upjohn Co Estere af substituerede hydroxyacetyl-piperazin-phenyl-oxazolidinoner
MY116093A (en) * 1996-02-26 2003-11-28 Upjohn Co Azolyl piperazinyl phenyl oxazolidinone antimicrobials
US6218413B1 (en) * 1997-05-30 2001-04-17 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
GB9812019D0 (en) * 1998-06-05 1998-07-29 Zeneca Ltd Chemical compounds

Also Published As

Publication number Publication date
US6281210B1 (en) 2001-08-28
SK5972002A3 (en) 2003-01-09
WO2001044212A1 (en) 2001-06-21
NO20022811D0 (no) 2002-06-13
TW544449B (en) 2003-08-01
CO5261527A1 (es) 2003-03-31
HUP0203787A2 (hu) 2003-07-28
JP2003516977A (ja) 2003-05-20
AR026547A1 (es) 2003-02-19
ES2236006T3 (es) 2005-07-16
BR0015177A (pt) 2002-06-18
EA200200673A1 (ru) 2002-12-26
PL355369A1 (en) 2004-04-19
KR20020062332A (ko) 2002-07-25
ATE288423T1 (de) 2005-02-15
CZ20022389A3 (cs) 2002-10-16
MXPA02005909A (es) 2002-10-23
PT1242395E (pt) 2005-05-31
ZA200202953B (en) 2003-09-23
CA2387047A1 (en) 2001-06-21
PE20010851A1 (es) 2001-08-17
DE60017941T2 (de) 2006-03-30
AU1805801A (en) 2001-06-25
CN1390211A (zh) 2003-01-08
EP1242395A1 (en) 2002-09-25
NO20022811L (no) 2002-06-13
DE60017941D1 (de) 2005-03-10
HUP0203787A3 (en) 2005-06-28
EP1242395B1 (en) 2005-02-02

Similar Documents

Publication Publication Date Title
IL150031A0 (en) Benzoic acid esters of oxazolidines having a hydroxyacetylpiperazine substituent
EE05215B1 (et) Meetod tskloproplkarbokslhappe estrite ja derivaatide valmistamiseks
IL146288A0 (en) Vla-4 inhibitor compounds
HUP0200638A2 (en) Compounds derived from benzoic acid esters, composition containing said compounds and use thereof
EP1219662A4 (en) POLYAMIDSÄUREESTER
IL145954A0 (en) A new inhibitor of carboxypeptidase u
HUP0105011A3 (en) Synthesis method of nitroxymethylphenyl esters of aspirin derivatives
IL147216A0 (en) Arylsulfonamido-substituted hydroxamic acid derivatives
ZA9810298B (en) Isothiazole carboxylic acid derivatives
HUP0201766A2 (en) A process for obtaining (nitroxymethyl) phenyl esters of salicylic acid derivatives
HK1047274A1 (zh) 氨基苯甲酸衍生物
IL145953A0 (en) A new inhibitor of carboxypeptidase u
GB9929979D0 (en) Hydroxamic acid derivatives
PL335601A1 (en) Derivatives of 2-substituted benzoylcycloalkyl carboxylic acid
SI1242395T1 (en) Benzoic acid esters of oxazolidinones having a hydroxyacetylpiperazine substituent
IL164773A0 (en) Ester derivatives of a decahydroisoquinoline-3-carboxlic acid as analgesics
IL146171A0 (en) A proceess for the purification of diacerein
GB9907082D0 (en) The preparation of carboxylic acid derivatives
AU2001289723A1 (en) Novel use of difluoromalonic acid esters
GB9817348D0 (en) Pharmaceutical use of esters
PL358688A1 (en) Carbamic acid esters as inhibitors of factor xa
PL345621A1 (en) Α-amino acid phenyl ester derivatives
HU9904011D0 (en) Novel salts of dipeptid derivatives
PL368419A1 (en) Novel $g(a)-oxygenated or $g(a)-thiolated carboxylic acid phenethylamide derivatives
GB9924911D0 (en) Novel phosphonocarboxylic acid esters