BG98194A - Фибриногенни рецепторни антагонисти - Google Patents

Фибриногенни рецепторни антагонисти Download PDF

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Publication number
BG98194A
BG98194A BG98194A BG9819493A BG98194A BG 98194 A BG98194 A BG 98194A BG 98194 A BG98194 A BG 98194A BG 9819493 A BG9819493 A BG 9819493A BG 98194 A BG98194 A BG 98194A
Authority
BG
Bulgaria
Prior art keywords
agent
mammal
pharmaceutically acceptable
administered
inhibiting
Prior art date
Application number
BG98194A
Other languages
Bulgarian (bg)
English (en)
Inventor
Mark Duggan
George Hartman
Melissa Egbertson
Nathan Ihle
Laura Turchi
Wiliam Hoffman
Original Assignee
Merck & Co. Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co. Inc. filed Critical Merck & Co. Inc.
Publication of BG98194A publication Critical patent/BG98194A/bg

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms
    • C07D211/76—Oxygen atoms attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/06—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Materials For Medical Uses (AREA)
BG98194A 1991-05-07 1993-11-02 Фибриногенни рецепторни антагонисти BG98194A (bg)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US69689391A 1991-05-07 1991-05-07
US72035791A 1991-06-25 1991-06-25
US87126292A 1992-04-23 1992-04-23
PCT/US1992/003463 WO1992019595A1 (en) 1991-05-07 1992-04-27 Fibrinogen receptor antagonists

Publications (1)

Publication Number Publication Date
BG98194A true BG98194A (bg) 1994-09-30

Family

ID=27418643

Family Applications (1)

Application Number Title Priority Date Filing Date
BG98194A BG98194A (bg) 1991-05-07 1993-11-02 Фибриногенни рецепторни антагонисти

Country Status (20)

Country Link
US (2) US5281585A (ja)
EP (1) EP0512831B1 (ja)
JP (1) JP2531562B2 (ja)
KR (1) KR920021531A (ja)
CN (1) CN1067883A (ja)
AT (1) ATE184874T1 (ja)
AU (1) AU647618B2 (ja)
BG (1) BG98194A (ja)
CA (1) CA2068064C (ja)
DE (1) DE69230013T2 (ja)
ES (1) ES2137175T3 (ja)
FI (1) FI934894A0 (ja)
HU (1) HUT68769A (ja)
IE (1) IE921463A1 (ja)
IL (1) IL101779A0 (ja)
MX (1) MXPA92002103A (ja)
NO (1) NO933999D0 (ja)
NZ (1) NZ242609A (ja)
WO (1) WO1992019595A1 (ja)
YU (1) YU47992A (ja)

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US5753659A (en) * 1993-03-29 1998-05-19 Zeneca Limited Heterocyclic compouds
CZ250995A3 (en) * 1993-03-29 1996-01-17 Zeneca Ltd Pyridine derivatives, process of their preparation and intermediates employed in this process as well as pharmaceutical compositions containing thereof
GB9313285D0 (en) * 1993-06-28 1993-08-11 Zeneca Ltd Acid derivatives
US5463011A (en) * 1993-06-28 1995-10-31 Zeneca Limited Acid derivatives
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Also Published As

Publication number Publication date
NO933999L (no) 1993-11-05
CA2068064C (en) 2001-01-02
WO1992019595A1 (en) 1992-11-12
MXPA92002103A (es) 2005-08-25
EP0512831B1 (en) 1999-09-22
IL101779A0 (en) 1992-12-30
ATE184874T1 (de) 1999-10-15
DE69230013D1 (de) 1999-10-28
ES2137175T3 (es) 1999-12-16
NO933999D0 (no) 1993-11-05
IE921463A1 (en) 1992-11-18
AU1611192A (en) 1992-11-12
CN1067883A (zh) 1993-01-13
JP2531562B2 (ja) 1996-09-04
EP0512831A1 (en) 1992-11-11
AU647618B2 (en) 1994-03-24
FI934894A (fi) 1993-11-05
US5281585A (en) 1994-01-25
KR920021531A (ko) 1992-12-18
HU9303145D0 (en) 1994-01-28
HUT68769A (en) 1995-07-28
NZ242609A (en) 1995-04-27
US5455243A (en) 1995-10-03
JPH069525A (ja) 1994-01-18
DE69230013T2 (de) 2000-04-27
CA2068064A1 (en) 1992-11-08
FI934894A0 (fi) 1993-11-05
YU47992A (sh) 1995-03-27

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