BG91821A - Метод за получаване на производни на хиназолина - Google Patents

Метод за получаване на производни на хиназолина

Info

Publication number
BG91821A
BG91821A BG091821A BG9182190A BG91821A BG 91821 A BG91821 A BG 91821A BG 091821 A BG091821 A BG 091821A BG 9182190 A BG9182190 A BG 9182190A BG 91821 A BG91821 A BG 91821A
Authority
BG
Bulgaria
Prior art keywords
quinazoline derivatives
obtaining
obtaining quinazoline
derivatives
quinazoline
Prior art date
Application number
BG091821A
Other languages
Bulgarian (bg)
English (en)
Inventor
Jozsef Reiter
Laszlo Pongo
Frigyes Goergenyi
Marton Fekete
Margit Csoergo
Ilona Sztuhar
Original Assignee
Egis Gyogyszergyar Rt.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU193189A external-priority patent/HU203342B/hu
Priority claimed from HU193089A external-priority patent/HU203333B/hu
Application filed by Egis Gyogyszergyar Rt. filed Critical Egis Gyogyszergyar Rt.
Publication of BG91821A publication Critical patent/BG91821A/bg

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
BG091821A 1989-04-21 1990-04-20 Метод за получаване на производни на хиназолина BG91821A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU193189A HU203342B (en) 1989-04-21 1989-04-21 Process for producing quinazoline deivatives
HU193089A HU203333B (en) 1989-04-21 1989-04-21 Process for producing n-cyano-carboxamidine derivatives

Publications (1)

Publication Number Publication Date
BG91821A true BG91821A (bg) 1993-12-24

Family

ID=26317437

Family Applications (1)

Application Number Title Priority Date Filing Date
BG091821A BG91821A (bg) 1989-04-21 1990-04-20 Метод за получаване на производни на хиназолина

Country Status (16)

Country Link
JP (1) JPH02292282A (de)
KR (1) KR900016194A (de)
AT (1) AT398075B (de)
BG (1) BG91821A (de)
CA (2) CA2015066A1 (de)
CH (1) CH681300A5 (de)
DK (1) DK99090A (de)
ES (1) ES2019826A6 (de)
FI (1) FI902002A0 (de)
GB (1) GB2231571B (de)
GR (1) GR900100294A (de)
IT (1) IT1241128B (de)
PL (1) PL162976B1 (de)
RU (1) RU1838309C (de)
SE (1) SE9001402L (de)
YU (1) YU70890A (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2077252C (en) * 1992-08-31 2001-04-10 Khashayar Karimian Methods of making ureas and guanidines, and intermediates therefor
ES2096518B1 (es) * 1994-03-28 1997-12-01 Grupo Farmaceutico Almirall S Nuevas anilinas.
WO2008015525A2 (en) * 2006-07-31 2008-02-07 Orchid Chemicals & Pharmaceuticals Limited An improved process for the preparation of alfuzosin hydrochloride
WO2008152514A2 (en) 2007-05-04 2008-12-18 Actavis Group Ptc Ehf Process for the preparation of alfuzosin and salts thereof
EP2178864B1 (de) 2007-08-02 2014-07-23 Cipla Limited Verfahren zur Herstellung von Alfuzosinhydrochlorid

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4026894A (en) * 1975-10-14 1977-05-31 Abbott Laboratories Antihypertensive agents
US4044135A (en) * 1975-10-14 1977-08-23 Abbott Laboratories Antihypertensive agents
GB1591490A (en) * 1977-08-04 1981-06-24 Abbott Lab 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine hydrochloride dihydrate
US4138561A (en) * 1977-09-30 1979-02-06 Bristol-Myers Company Cyanocarboxamidines and quinazoline process
FI56836C (fi) * 1977-10-25 1980-04-10 Fermion Oy 4-substituerade piperazin-1-(n-aryl-n'-cyano)-karboximidamider som aer mellanprodukter vid framstaellningen av farmakologiskt vaerdefulla 6,7-dimetoxi- eller 6,7,8-trimetoxi-4-amino-2-(4-substituerade-piperazin-1-yl)-kinazoliner
FI57751C (fi) * 1977-10-25 1980-10-10 Fermion Oy Foerfarande foer framstaellning av 6,7-dimetoxi- eller 6,7,8-trimetoxi-4-amino-2-(4-substituerade-piperazin-1-yl)-kinazoliner med blodtryckssaenkande verkan
FR2421888A1 (fr) * 1978-02-06 1979-11-02 Synthelabo Amides d'alkylene-diamines et leur application en therapeutique
FI59800C (fi) * 1979-01-10 1981-10-12 Fermion Oy Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(furo-2-yl)-piperazin-1-yl)-kinazolin
FI67699C (fi) * 1979-01-31 1985-05-10 Orion Yhtymae Oy Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-1-piperazinyl)kinazolinhydroklorid med blodtryckssaenkande verkan
EP0146642B1 (de) * 1983-11-22 1988-01-20 LUDWIG HEUMANN & CO GMBH Verfahren zur Herstellung von 4-Amino-6,7-dimethoxy-2-(4-(furo-2-yl)-piperazin-1-yl)-chinazolin und dessen physiologisch annehmbarer Salze

Also Published As

Publication number Publication date
IT1241128B (it) 1993-12-29
FI902002A0 (fi) 1990-04-20
CA2028953A1 (en) 1990-10-22
ATA93190A (de) 1994-01-15
DK99090A (da) 1990-10-22
GB2231571B (en) 1992-09-16
PL162976B1 (pl) 1994-01-31
GB2231571A (en) 1990-11-21
SE9001402L (sv) 1990-10-22
IT9020092A0 (it) 1990-04-20
KR900016194A (ko) 1990-11-12
DK99090D0 (da) 1990-04-20
GR900100294A (el) 1991-09-27
CH681300A5 (de) 1993-02-26
RU1838309C (ru) 1993-08-30
CA2015066A1 (en) 1990-10-21
YU70890A (en) 1992-05-28
SE9001402D0 (sv) 1990-04-20
PL284860A1 (en) 1991-03-11
AT398075B (de) 1994-09-26
JPH02292282A (ja) 1990-12-03
GB9008941D0 (en) 1990-06-20
ES2019826A6 (es) 1991-07-01
IT9020092A1 (it) 1991-10-20

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