DE69003465D1 - Chinazolinderivate. - Google Patents

Chinazolinderivate.

Info

Publication number
DE69003465D1
DE69003465D1 DE90304979T DE69003465T DE69003465D1 DE 69003465 D1 DE69003465 D1 DE 69003465D1 DE 90304979 T DE90304979 T DE 90304979T DE 69003465 T DE69003465 T DE 69003465T DE 69003465 D1 DE69003465 D1 DE 69003465D1
Authority
DE
Germany
Prior art keywords
quinazoline derivatives
quinazoline
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE90304979T
Other languages
English (en)
Other versions
DE69003465T2 (de
Inventor
Thomas Henry Brown
Robert John Ife
Colin Andrew Leach
David John Keeling
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Intercredit BV
Original Assignee
SmithKline Beecham Intercredit BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898910722A external-priority patent/GB8910722D0/en
Priority claimed from GB898918703A external-priority patent/GB8918703D0/en
Priority claimed from GB898928251A external-priority patent/GB8928251D0/en
Application filed by SmithKline Beecham Intercredit BV filed Critical SmithKline Beecham Intercredit BV
Publication of DE69003465D1 publication Critical patent/DE69003465D1/de
Application granted granted Critical
Publication of DE69003465T2 publication Critical patent/DE69003465T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE90304979T 1989-05-10 1990-05-09 Chinazolinderivate. Expired - Fee Related DE69003465T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB898910722A GB8910722D0 (en) 1989-05-10 1989-05-10 Compounds
GB898918703A GB8918703D0 (en) 1989-08-16 1989-08-16 Compounds
GB898928251A GB8928251D0 (en) 1989-12-14 1989-12-14 Compounds

Publications (2)

Publication Number Publication Date
DE69003465D1 true DE69003465D1 (de) 1993-10-28
DE69003465T2 DE69003465T2 (de) 1994-01-20

Family

ID=27264472

Family Applications (1)

Application Number Title Priority Date Filing Date
DE90304979T Expired - Fee Related DE69003465T2 (de) 1989-05-10 1990-05-09 Chinazolinderivate.

Country Status (9)

Country Link
EP (1) EP0404322B1 (de)
JP (1) JPH0317068A (de)
KR (1) KR900018047A (de)
AU (1) AU627576B2 (de)
CA (1) CA2015981A1 (de)
DE (1) DE69003465T2 (de)
IE (1) IE901683L (de)
NZ (1) NZ233598A (de)
PT (1) PT93982A (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT100905A (pt) * 1991-09-30 1994-02-28 Eisai Co Ltd Compostos heterociclicos azotados biciclicos contendo aneis de benzeno, ciclo-hexano ou piridina e de pirimidina, piridina ou imidazol substituidos e composicoes farmaceuticas que os contem
KR0144833B1 (ko) 1992-12-28 1998-07-15 김태훈 신규의 퀴나졸린 유도체 및 그의 제조방법
IN188411B (de) * 1997-03-27 2002-09-21 Yuhan Corp
WO2003055866A1 (en) * 2001-12-21 2003-07-10 Bayer Pharmaceuticals Corporation Quinazoline and quinoline derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents
US8309562B2 (en) 2003-07-03 2012-11-13 Myrexis, Inc. Compounds and therapeutical use thereof
EP1660092A2 (de) * 2003-07-03 2006-05-31 Myriad Genetics, Inc. 4-arylamino-chinazoline als aktivatoren von caspasen und apoptose-auslöser
US8258145B2 (en) 2005-01-03 2012-09-04 Myrexis, Inc. Method of treating brain cancer
US7981908B2 (en) 2005-05-11 2011-07-19 Vecta, Ltd. Compositions and methods for inhibiting gastric acid secretion
US7803817B2 (en) 2005-05-11 2010-09-28 Vecta, Ltd. Composition and methods for inhibiting gastric acid secretion
RU2467747C2 (ru) 2006-07-25 2012-11-27 Векта Лтд. Композиции и способы для ингибирования секреции желудочной кислоты с использованием производных малых дикарбоновых кислот в сочетании с ppi
EP3722297A1 (de) * 2015-03-04 2020-10-14 Gilead Sciences, Inc. Toll-like-rezeptor-modulator-verbindungen
AU2017318601B2 (en) 2016-09-02 2020-09-03 Gilead Sciences, Inc. Toll like receptor modulator compounds
TWI751517B (zh) 2019-04-17 2022-01-01 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TW202210480A (zh) 2019-04-17 2022-03-16 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TW202115056A (zh) 2019-06-28 2021-04-16 美商基利科學股份有限公司 類鐸受體調節劑化合物的製備方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3663706A (en) * 1969-09-29 1972-05-16 Pfizer Use of 2,4-diaminoquinazolines as hypotensive agents
DK140695C (da) * 1976-05-07 1980-05-12 Synthelabo Analogifremgangsmaade til fremstilling af 2,4-diamino-6,7-dimethoxyquinazolinderivater eller syreadditionssalte heraf
US4098788A (en) * 1977-06-20 1978-07-04 Bristol-Myers Company Process for preparing quinazolines
US4287341A (en) * 1979-11-01 1981-09-01 Pfizer Inc. Alkoxy-substituted-6-chloro-quinazoline-2,4-diones
YU47288B (sh) * 1987-07-11 1995-01-31 Schering Agrochemicals Limited Akrilatni fungicidi i postupak za njihovo dobijanje
IL88507A (en) * 1987-12-03 1993-02-21 Smithkline Beckman Intercredit 2,4-diaminoquinazolines, process for their preparation and pharmaceutical compositions comprising them
AU610328B2 (en) * 1987-12-03 1991-05-16 Smithkline Beckman Intercredit B.V. 2,4- diaminoquinazoline derivatives
IL89027A (en) * 1988-01-29 1993-01-31 Lilly Co Eli Quinazoline derivatives, process for their preparation and fungicidal, insecticidal and miticidal compositions containing them

Also Published As

Publication number Publication date
CA2015981A1 (en) 1990-11-10
PT93982A (pt) 1991-01-08
NZ233598A (en) 1991-04-26
EP0404322B1 (de) 1993-09-22
JPH0317068A (ja) 1991-01-25
AU627576B2 (en) 1992-08-27
DE69003465T2 (de) 1994-01-20
IE901683L (en) 1990-11-10
AU5486490A (en) 1990-11-15
KR900018047A (ko) 1990-12-20
EP0404322A1 (de) 1990-12-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee