BG64700B1 - Заместени 2-бензиламино-2-фенилацетамиди - Google Patents

Заместени 2-бензиламино-2-фенилацетамиди Download PDF

Info

Publication number
BG64700B1
BG64700B1 BG104569A BG10456900A BG64700B1 BG 64700 B1 BG64700 B1 BG 64700B1 BG 104569 A BG104569 A BG 104569A BG 10456900 A BG10456900 A BG 10456900A BG 64700 B1 BG64700 B1 BG 64700B1
Authority
BG
Bulgaria
Prior art keywords
benzylamino
phenylacetamide
compound
pharmaceutically acceptable
fluorobenzyloxy
Prior art date
Application number
BG104569A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG104569A (en
Inventor
Paolo Pevarello
Mario Varasi
Patricia Salvati
Claes Post
Original Assignee
Newron Pharmaceuticals S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Newron Pharmaceuticals S.P.A. filed Critical Newron Pharmaceuticals S.P.A.
Publication of BG104569A publication Critical patent/BG104569A/xx
Publication of BG64700B1 publication Critical patent/BG64700B1/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BG104569A 1997-12-31 2000-06-28 Заместени 2-бензиламино-2-фенилацетамиди BG64700B1 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9727521.8A GB9727521D0 (en) 1997-12-31 1997-12-31 Substituted 2-benzylamino-2-phenyl-acetamide compounds

Publications (2)

Publication Number Publication Date
BG104569A BG104569A (en) 2001-02-28
BG64700B1 true BG64700B1 (bg) 2005-12-30

Family

ID=10824340

Family Applications (1)

Application Number Title Priority Date Filing Date
BG104569A BG64700B1 (bg) 1997-12-31 2000-06-28 Заместени 2-бензиламино-2-фенилацетамиди

Country Status (23)

Country Link
US (1) US6303819B1 (cs)
EP (1) EP1044186B9 (cs)
JP (1) JP3839665B2 (cs)
KR (1) KR100629628B1 (cs)
AT (1) ATE319680T1 (cs)
BG (1) BG64700B1 (cs)
CA (1) CA2316082C (cs)
CZ (1) CZ296722B6 (cs)
DE (1) DE69833797T2 (cs)
EA (1) EA003097B1 (cs)
ES (1) ES2256976T3 (cs)
GB (1) GB9727521D0 (cs)
HK (1) HK1028021A1 (cs)
HR (1) HRP20000508B9 (cs)
HU (1) HUP0100184A3 (cs)
ID (1) ID26622A (cs)
IL (1) IL136735A0 (cs)
NO (1) NO327259B1 (cs)
NZ (1) NZ505441A (cs)
PL (1) PL194745B1 (cs)
PT (1) PT1044186E (cs)
TR (1) TR200001950T2 (cs)
WO (1) WO1999035123A1 (cs)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9727523D0 (en) * 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
WO2002048114A1 (en) * 2000-11-27 2002-06-20 Pharmacia Italia S.P.A. Phenylacetamido- pyrazole derivatives and their use as antitumor agents
WO2003020273A2 (en) 2001-09-03 2003-03-13 Newron Pharmaceuticals Spa Pharmaceutical composition comprising gabapentin or an analogue thereof and an $g(a)-aminoamide and its analgesic use
US6667327B2 (en) 2002-02-04 2003-12-23 Hoffmann-La Roche Inc. Pyridine amido derivatives
EP1438956A1 (en) 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful as antimigraine agents
WO2004087125A1 (en) * 2003-04-02 2004-10-14 Ionix Pharmaceuticals Limited Amino acid derivatives as inhibitors of mammalian sodium channels
EP1524267A1 (en) * 2003-10-15 2005-04-20 Newron Pharmaceuticals S.p.A. Substituted benzylaminoalkylene heterocycles
CN100441188C (zh) 2003-10-23 2008-12-10 弗·哈夫曼-拉罗切有限公司 作为mao－b抑制剂的苯并氮杂衍生物
EP1533298A1 (en) 2003-11-21 2005-05-25 Newron Pharmaceuticals S.p.A. 3-aminopyrrolidone derivatives
EP1533302A1 (en) * 2003-11-21 2005-05-25 Newron Pharmaceuticals S.p.A. Histidine derivatives
EP1535908A1 (en) 2003-11-24 2005-06-01 Newron Pharmaceuticals S.p.A. N-acyl-N'-benzyl-alkylendiamino drivatives
EP1588704A1 (en) 2004-04-22 2005-10-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders
AU2005282028B2 (en) * 2004-09-10 2011-03-24 Newron Pharmaceuticals S.P.A. (halobenzyloxy) benzylamino-propanamides as sodium and/or calcium channel selective modulators
CA2629065C (en) * 2005-12-22 2013-08-06 Newron Pharmaceuticals S.P.A. 2 -phenylethylamino derivatives as calcium and/or sodium channel modulators
EP1870097A1 (en) 2006-06-15 2007-12-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of cognitive disorders
KR101132534B1 (ko) * 2007-03-05 2012-08-22 에프. 호프만-라 로슈 아게 오렉신 길항제로서의 아미노아마이드
US11111208B2 (en) * 2019-06-17 2021-09-07 RK Pharma Solutions LLC Process for the preparation of safinamide mesylate intermediate

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5688830A (en) * 1996-01-25 1997-11-18 Syntex (U.S.A.) Inc. Treatment of neuropathic pain

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5541204A (en) * 1994-12-02 1996-07-30 Bristol-Myers Squibb Company Aryloxypropanolamine β 3 adrenergic agonists
KR0147963B1 (ko) * 1995-01-10 1998-08-17 강박광 엔-아릴알킬페닐아세트아미드 유도체와 그의 제조방법

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5688830A (en) * 1996-01-25 1997-11-18 Syntex (U.S.A.) Inc. Treatment of neuropathic pain

Also Published As

Publication number Publication date
DE69833797T2 (de) 2006-10-19
NO20003398L (no) 2000-08-02
EA003097B1 (ru) 2002-12-26
IL136735A0 (en) 2001-06-14
CA2316082C (en) 2006-02-07
HRP20000508A2 (en) 2001-02-28
JP2002500214A (ja) 2002-01-08
KR100629628B1 (ko) 2006-09-29
EA200000728A1 (ru) 2001-02-26
PL341514A1 (en) 2001-04-23
HRP20000508B1 (en) 2007-02-28
HUP0100184A3 (en) 2002-11-28
CZ20002496A3 (cs) 2000-12-13
HRP20000508B9 (en) 2008-05-31
BG104569A (en) 2001-02-28
NO20003398D0 (no) 2000-06-29
NZ505441A (en) 2001-12-21
WO1999035123A1 (en) 1999-07-15
DE69833797D1 (de) 2006-05-04
ATE319680T1 (de) 2006-03-15
US6303819B1 (en) 2001-10-16
PL194745B1 (pl) 2007-06-29
ES2256976T3 (es) 2006-07-16
EP1044186B1 (en) 2006-03-08
KR20010033779A (ko) 2001-04-25
HUP0100184A2 (hu) 2001-07-30
JP3839665B2 (ja) 2006-11-01
NO327259B1 (no) 2009-05-25
GB9727521D0 (en) 1998-02-25
HK1028021A1 (en) 2001-02-02
ID26622A (id) 2001-01-25
CZ296722B6 (cs) 2006-05-17
EP1044186A1 (en) 2000-10-18
EP1044186B9 (en) 2006-06-21
PT1044186E (pt) 2006-07-31
CA2316082A1 (en) 1999-07-15
TR200001950T2 (tr) 2000-11-21

Similar Documents

Publication Publication Date Title
BG64700B1 (bg) Заместени 2-бензиламино-2-фенилацетамиди
KR100525587B1 (ko) 알파-아미노아미드 유도체 및 이를 포함하는 진통제용 약제학적 조성물
US4559337A (en) 8-Chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-(alkoxy-containing acyl)hydrazides
RU2424230C2 (ru) Соединения и способы ингибирования взаимодействия белков bcl с компонентами связывания
EA001322B1 (ru) Производные 2-(4-замещенного)-бензиламино-2-метилпропанамида
US5446066A (en) Substituted (arylalkoxybenzyl)aminopropanamide derivatives and process for their preparation
US5912242A (en) N-(4-substituted-benzyl)-2-aminolactam derivatives
KR20000048601A (ko) 니트론 유도체
DE3687035T2 (de) 3-aminopropyloxyphenylabkoemmlinge, herstellung und arzneitmittel die sie enthalten.
AU3959893A (en) N-aryloxy(thio)alkyl-azacycloalkanes useful as calcium channel antagonists
MXPA00006354A (en) Substituted 2-benzylamino-2-phenyl-acetamide compounds
US5093355A (en) Benzylpyrrolidine derivatives as dopamine agonists
JPH11180950A (ja) ヒドロキサム酸化合物
FR2827863A1 (fr) Derives d'aminoalkylimidazole, leur preparation et leur utilisation en therapeutique
MXPA00006352A (en) Alpha-aminoamide derivatives useful as analgesic agents