HRP20000508B9 - Substituted 2-benzylamino-2-phenyl-acetamide compounds - Google Patents
Substituted 2-benzylamino-2-phenyl-acetamide compoundsInfo
- Publication number
- HRP20000508B9 HRP20000508B9 HR20000508A HRP20000508A HRP20000508B9 HR P20000508 B9 HRP20000508 B9 HR P20000508B9 HR 20000508 A HR20000508 A HR 20000508A HR P20000508 A HRP20000508 A HR P20000508A HR P20000508 B9 HRP20000508 B9 HR P20000508B9
- Authority
- HR
- Croatia
- Prior art keywords
- benzylamino
- phenyl
- substituted
- acetamide compounds
- alkyl
- Prior art date
Links
- PYVTTZQYAVUMNV-UHFFFAOYSA-N 2-(benzylamino)-2-phenylacetamide Chemical class C=1C=CC=CC=1C(C(=O)N)NCC1=CC=CC=C1 PYVTTZQYAVUMNV-UHFFFAOYSA-N 0.000 title abstract 2
- 150000002431 hydrogen Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9727521.8A GB9727521D0 (en) | 1997-12-31 | 1997-12-31 | Substituted 2-benzylamino-2-phenyl-acetamide compounds |
| PCT/EP1998/008158 WO1999035123A1 (en) | 1997-12-31 | 1998-12-12 | Substituted 2-benzylamino-2-phenyl-acetamide compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| HRP20000508A2 HRP20000508A2 (en) | 2001-02-28 |
| HRP20000508B1 HRP20000508B1 (en) | 2007-02-28 |
| HRP20000508B9 true HRP20000508B9 (en) | 2008-05-31 |
Family
ID=10824340
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20000508A HRP20000508B9 (en) | 1997-12-31 | 2000-07-27 | Substituted 2-benzylamino-2-phenyl-acetamide compounds |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US6303819B1 (cs) |
| EP (1) | EP1044186B9 (cs) |
| JP (1) | JP3839665B2 (cs) |
| KR (1) | KR100629628B1 (cs) |
| AT (1) | ATE319680T1 (cs) |
| BG (1) | BG64700B1 (cs) |
| CA (1) | CA2316082C (cs) |
| CZ (1) | CZ296722B6 (cs) |
| DE (1) | DE69833797T2 (cs) |
| EA (1) | EA003097B1 (cs) |
| ES (1) | ES2256976T3 (cs) |
| GB (1) | GB9727521D0 (cs) |
| HK (1) | HK1028021A1 (cs) |
| HR (1) | HRP20000508B9 (cs) |
| HU (1) | HUP0100184A3 (cs) |
| ID (1) | ID26622A (cs) |
| IL (1) | IL136735A0 (cs) |
| NO (1) | NO327259B1 (cs) |
| NZ (1) | NZ505441A (cs) |
| PL (1) | PL194745B1 (cs) |
| PT (1) | PT1044186E (cs) |
| TR (1) | TR200001950T2 (cs) |
| WO (1) | WO1999035123A1 (cs) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9727523D0 (en) * | 1997-12-31 | 1998-02-25 | Pharmacia & Upjohn Spa | Alpha-aminoamide derivatives useful as analgesic agents |
| MXPA03004644A (es) * | 2000-11-27 | 2003-09-05 | Pharmacia Italia Spa | Derivados de fenilacetamdia-pirazol y su uso como agentes antitumorales. |
| ES2253579T3 (es) | 2001-09-03 | 2006-06-01 | Newron Pharmaceuticals S.P.A. | Composicion farmaceutica que comprende gabapentina o un analogo suyo y una alfa-aminoamida y su uso analgesico. |
| US6667327B2 (en) | 2002-02-04 | 2003-12-23 | Hoffmann-La Roche Inc. | Pyridine amido derivatives |
| EP1438956A1 (en) | 2003-01-16 | 2004-07-21 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful as antimigraine agents |
| WO2004087125A1 (en) * | 2003-04-02 | 2004-10-14 | Ionix Pharmaceuticals Limited | Amino acid derivatives as inhibitors of mammalian sodium channels |
| EP1524267A1 (en) * | 2003-10-15 | 2005-04-20 | Newron Pharmaceuticals S.p.A. | Substituted benzylaminoalkylene heterocycles |
| AU2004283452A1 (en) | 2003-10-23 | 2005-05-06 | F. Hoffmann-La Roche Ag | Benzazepine derivatives as MAO-B inhibitors |
| EP1533302A1 (en) * | 2003-11-21 | 2005-05-25 | Newron Pharmaceuticals S.p.A. | Histidine derivatives |
| EP1533298A1 (en) | 2003-11-21 | 2005-05-25 | Newron Pharmaceuticals S.p.A. | 3-aminopyrrolidone derivatives |
| EP1535908A1 (en) | 2003-11-24 | 2005-06-01 | Newron Pharmaceuticals S.p.A. | N-acyl-N'-benzyl-alkylendiamino drivatives |
| EP1588704A1 (en) | 2004-04-22 | 2005-10-26 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders |
| US20080096965A1 (en) * | 2004-09-10 | 2008-04-24 | Newron Pharmaceuticals S.P.A. | (Halobenzyloxy) Benzylamino-Propanamides as Sodium and/or Calcium Channel Selective Modulators |
| US7855227B2 (en) * | 2005-12-22 | 2010-12-21 | Newron Pharmaceuticals S.P.A. | 2-phenylethylamino derivatives as calcium and/or sodium channel modulators |
| EP1870097A1 (en) | 2006-06-15 | 2007-12-26 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful in the treatment of cognitive disorders |
| CA2679039A1 (en) * | 2007-03-05 | 2008-09-12 | F. Hoffmann-La Roche Ag | Aminoamides as orexin antagonists |
| US11111208B2 (en) * | 2019-06-17 | 2021-09-07 | RK Pharma Solutions LLC | Process for the preparation of safinamide mesylate intermediate |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5541204A (en) * | 1994-12-02 | 1996-07-30 | Bristol-Myers Squibb Company | Aryloxypropanolamine β 3 adrenergic agonists |
| KR0147963B1 (ko) * | 1995-01-10 | 1998-08-17 | 강박광 | 엔-아릴알킬페닐아세트아미드 유도체와 그의 제조방법 |
| US5688830A (en) * | 1996-01-25 | 1997-11-18 | Syntex (U.S.A.) Inc. | Treatment of neuropathic pain |
-
1997
- 1997-12-31 GB GBGB9727521.8A patent/GB9727521D0/en not_active Ceased
-
1998
- 1998-12-12 JP JP2000527525A patent/JP3839665B2/ja not_active Expired - Fee Related
- 1998-12-12 EP EP98964511A patent/EP1044186B9/en not_active Expired - Lifetime
- 1998-12-12 CZ CZ20002496A patent/CZ296722B6/cs not_active IP Right Cessation
- 1998-12-12 EA EA200000728A patent/EA003097B1/ru not_active IP Right Cessation
- 1998-12-12 TR TR2000/01950T patent/TR200001950T2/xx unknown
- 1998-12-12 ES ES98964511T patent/ES2256976T3/es not_active Expired - Lifetime
- 1998-12-12 CA CA002316082A patent/CA2316082C/en not_active Expired - Fee Related
- 1998-12-12 AT AT98964511T patent/ATE319680T1/de not_active IP Right Cessation
- 1998-12-12 KR KR1020007007306A patent/KR100629628B1/ko not_active IP Right Cessation
- 1998-12-12 IL IL13673598A patent/IL136735A0/xx not_active IP Right Cessation
- 1998-12-12 DE DE69833797T patent/DE69833797T2/de not_active Expired - Fee Related
- 1998-12-12 PT PT98964511T patent/PT1044186E/pt unknown
- 1998-12-12 HU HU0100184A patent/HUP0100184A3/hu unknown
- 1998-12-12 ID IDW20001444A patent/ID26622A/id unknown
- 1998-12-12 NZ NZ505441A patent/NZ505441A/en unknown
- 1998-12-12 PL PL98341514A patent/PL194745B1/pl not_active IP Right Cessation
- 1998-12-12 WO PCT/EP1998/008158 patent/WO1999035123A1/en active IP Right Grant
- 1998-12-12 US US09/581,254 patent/US6303819B1/en not_active Expired - Fee Related
-
2000
- 2000-06-28 BG BG104569A patent/BG64700B1/bg unknown
- 2000-06-29 NO NO20003398A patent/NO327259B1/no not_active IP Right Cessation
- 2000-07-27 HR HR20000508A patent/HRP20000508B9/xx not_active IP Right Cessation
- 2000-11-20 HK HK00107399A patent/HK1028021A1/xx not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A1OB | Publication of a patent application | ||
| AIPI | Request for the grant of a patent on the basis of a substantive examination of a patent application | ||
| ARAI | Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application | ||
| PNAN | Change of the applicant name, address/residence |
Owner name: NEWRON PHARMACEUTICALS S.P.A., IT |
|
| B1PR | Patent granted | ||
| B9IS | Complete republication of an hr-b document | ||
| B9IS | Complete republication of an hr-b document | ||
| ODRP | Renewal fee for the maintenance of a patent |
Payment date: 20081114 Year of fee payment: 11 |
|
| PBON | Lapse due to non-payment of renewal fee |
Effective date: 20091213 |