BG64647B1 - Метод за получаване на сертралин - Google Patents

Метод за получаване на сертралин Download PDF

Info

Publication number
BG64647B1
BG64647B1 BG108878A BG10887800A BG64647B1 BG 64647 B1 BG64647 B1 BG 64647B1 BG 108878 A BG108878 A BG 108878A BG 10887800 A BG10887800 A BG 10887800A BG 64647 B1 BG64647 B1 BG 64647B1
Authority
BG
Bulgaria
Prior art keywords
sertraline
mixture
cis
monomethylamine
trans
Prior art date
Application number
BG108878A
Other languages
Bulgarian (bg)
English (en)
Inventor
Juan Colberg
David PFISTERED
Geraldine Taber
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22102365&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BG64647(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of BG64647B1 publication Critical patent/BG64647B1/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/02—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Cephalosporin Compounds (AREA)
BG108878A 1998-01-16 2000-08-07 Метод за получаване на сертралин BG64647B1 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7160098P 1998-01-16 1998-01-16

Publications (1)

Publication Number Publication Date
BG64647B1 true BG64647B1 (bg) 2005-10-31

Family

ID=22102365

Family Applications (2)

Application Number Title Priority Date Filing Date
BG108878A BG64647B1 (bg) 1998-01-16 2000-08-07 Метод за получаване на сертралин
BG104669A BG64621B1 (bg) 1998-01-16 2000-08-07 Метод за получаване на кетимин

Family Applications After (1)

Application Number Title Priority Date Filing Date
BG104669A BG64621B1 (bg) 1998-01-16 2000-08-07 Метод за получаване на кетимин

Country Status (48)

Country Link
US (1) US6232500B1 (uk)
EP (1) EP1047666B1 (uk)
JP (1) JP3533179B2 (uk)
KR (1) KR100362788B1 (uk)
CN (1) CN1121381C (uk)
AP (1) AP956A (uk)
AR (1) AR016168A1 (uk)
AT (1) ATE231121T1 (uk)
AU (1) AU747861B2 (uk)
BG (2) BG64647B1 (uk)
BR (1) BR9814248A (uk)
CA (1) CA2315761C (uk)
CO (1) CO5040154A1 (uk)
CZ (1) CZ20002594A3 (uk)
DE (1) DE69810815T2 (uk)
DK (1) DK1047666T3 (uk)
DZ (1) DZ2705A1 (uk)
EA (1) EA004952B1 (uk)
EG (1) EG21515A (uk)
ES (1) ES2186226T3 (uk)
GT (1) GT199800176A (uk)
HK (1) HK1032039A1 (uk)
HN (1) HN1998000167A (uk)
HR (1) HRP20000473A2 (uk)
HU (1) HUP0101253A3 (uk)
ID (1) ID24971A (uk)
IL (2) IL136888A0 (uk)
IN (1) IN191358B (uk)
IS (1) IS5538A (uk)
MA (1) MA24744A1 (uk)
MY (1) MY132956A (uk)
NO (1) NO20003625L (uk)
NZ (1) NZ505027A (uk)
OA (1) OA11439A (uk)
PA (1) PA8461901A1 (uk)
PE (1) PE20000171A1 (uk)
PL (1) PL192489B1 (uk)
PT (1) PT1047666E (uk)
RS (1) RS49773B (uk)
SI (1) SI1047666T1 (uk)
SK (1) SK10182000A3 (uk)
TN (1) TNSN99004A1 (uk)
TR (1) TR200002065T2 (uk)
TW (1) TW505624B (uk)
UA (1) UA55504C2 (uk)
UY (1) UY25348A1 (uk)
WO (1) WO1999036394A1 (uk)
ZA (1) ZA99278B (uk)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU226423B1 (en) * 1998-05-05 2008-12-29 Egis Gyogyszergyar Nyrt Process for producing a 1(2h)-naphtalene-1-ylidene derivative
EP1124792B1 (de) * 1998-10-30 2004-08-04 Ciba SC Holding AG Verfahren zur herstellung von ketiminen
EP1630156A1 (en) * 1998-11-27 2006-03-01 Teva Pharmaceutical Industries Ltd Sertraline hydrochloride polymorphs
IN185109B (uk) * 1999-09-01 2000-11-18 Torrent Pharmaceuticals Ltd
ES2245652T3 (es) * 1999-11-16 2006-01-16 Ciba Specialty Chemicals Holding Inc. Procedimiento para la preparacion de cetiminas.
DE60020153T2 (de) * 1999-11-16 2006-01-26 Ciba Speciality Chemicals Holding Inc. Verfahren zur herstellung von ketiminen
IN187170B (uk) 2000-01-04 2002-02-23 Sun Pharmaceutical Ind Ltd
JP2003527359A (ja) * 2000-03-14 2003-09-16 テバ ファーマシューティカル インダストリーズ リミティド （＋）−シス−セルトラリンの製造のための新規方法
EP1397342A1 (en) * 2001-05-31 2004-03-17 Orion Corporation Fermion Process for preparing sertraline intermediates
US6723878B2 (en) 2001-06-15 2004-04-20 Orion Corporation Fermion Method for preparing sertraline
KR20030061474A (ko) * 2002-01-14 2003-07-22 한미약품 주식회사 서트랄린 제조용 중간체로서 사용되는 시스-라세메이트화합물의 개선된 제조방법
WO2006129324A2 (en) 2005-06-03 2006-12-07 Hetero Drugs Limited A highly stereoselective synthesis of sertraline

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4536518A (en) * 1979-11-01 1985-08-20 Pfizer Inc. Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine
US4855500A (en) * 1988-05-04 1989-08-08 Pfizer Inc. Process for preparing a ketimine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU226424B1 (en) 1998-05-05 2008-12-29 Egis Gyogyszergyar Nyrt Process for producing enantiomer mixture for preparation of sertraline

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4536518A (en) * 1979-11-01 1985-08-20 Pfizer Inc. Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine
US4855500A (en) * 1988-05-04 1989-08-08 Pfizer Inc. Process for preparing a ketimine

Also Published As

Publication number Publication date
HUP0101253A3 (en) 2002-06-28
MY132956A (en) 2007-10-31
YU44300A (sh) 2002-09-19
AR016168A1 (es) 2001-06-20
CO5040154A1 (es) 2001-05-29
EP1047666A1 (en) 2000-11-02
BG104669A (en) 2001-04-30
NZ505027A (en) 2002-08-28
BR9814248A (pt) 2000-10-10
EG21515A (en) 2001-11-28
WO1999036394A1 (en) 1999-07-22
OA11439A (en) 2004-04-26
AP956A (en) 2001-04-06
MA24744A1 (fr) 1999-10-01
HN1998000167A (es) 1999-02-09
JP2002509132A (ja) 2002-03-26
EP1047666B1 (en) 2003-01-15
CN1121381C (zh) 2003-09-17
DK1047666T3 (da) 2003-02-24
EA004952B1 (ru) 2004-10-28
HUP0101253A2 (hu) 2002-05-29
CA2315761C (en) 2004-08-31
GT199800176A (es) 1998-11-09
CZ20002594A3 (cs) 2001-12-12
IS5538A (is) 2000-06-16
TR200002065T2 (tr) 2000-11-21
RS49773B (sr) 2008-06-05
ES2186226T3 (es) 2003-05-01
CA2315761A1 (en) 1999-07-22
UA55504C2 (uk) 2003-04-15
ID24971A (id) 2000-08-31
PA8461901A1 (es) 2000-05-24
JP3533179B2 (ja) 2004-05-31
KR20010034117A (ko) 2001-04-25
AP9901441A0 (en) 1999-03-31
NO20003625L (no) 2000-09-13
TNSN99004A1 (fr) 2005-11-10
PE20000171A1 (es) 2000-03-09
EA200000661A1 (ru) 2000-12-25
KR100362788B1 (ko) 2002-11-29
AU9278698A (en) 1999-08-02
DE69810815D1 (de) 2003-02-20
PL192489B1 (pl) 2006-10-31
CN1285819A (zh) 2001-02-28
HRP20000473A2 (en) 2001-04-30
ZA99278B (en) 2000-07-17
NO20003625D0 (no) 2000-07-14
ATE231121T1 (de) 2003-02-15
DE69810815T2 (de) 2003-08-07
IL136888A0 (en) 2001-06-14
SI1047666T1 (en) 2003-04-30
PT1047666E (pt) 2003-03-31
AU747861B2 (en) 2002-05-23
HK1032039A1 (en) 2001-07-06
IL136888A (en) 2006-12-10
PL341648A1 (en) 2001-04-23
BG64621B1 (bg) 2005-09-30
UY25348A1 (es) 1999-09-27
IN191358B (uk) 2003-11-29
SK10182000A3 (sk) 2002-06-04
US6232500B1 (en) 2001-05-15
TW505624B (en) 2002-10-11
DZ2705A1 (fr) 2003-09-01

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