UY25348A1 - Procedimiento para preparar una cetoimina - Google Patents
Procedimiento para preparar una cetoiminaInfo
- Publication number
- UY25348A1 UY25348A1 UY25348A UY25348A UY25348A1 UY 25348 A1 UY25348 A1 UY 25348A1 UY 25348 A UY25348 A UY 25348A UY 25348 A UY25348 A UY 25348A UY 25348 A1 UY25348 A1 UY 25348A1
- Authority
- UY
- Uruguay
- Prior art keywords
- formula
- monomethylamine
- dichlorophenyl
- dihydro
- cetoimin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C249/02—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cephalosporin Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
Esta invención se refiere a un procedimiento para preparar N-[4,(3,4-diclorofenil)-3,4-dihidro-1(2H)-naftaleniliden]metanamina de fórmula l que comprende hacer reaccionar 4-(3,4-diclorofenil)-3,4-dihidro-1(2H)-naftalenona de fórmula ll y monometilamina en un alcohol como disolvente, seleccionado de alcanoles primarios, secundarios y terciarios, lineales o ramificados, y otro alcoholes que tengan un punto de ebullición en las condiciones de reacción, mayor que 55ºC y en los que sea soluble la monometilamina. Un procedimiento en el que la cetoimina producto de fórmula ll se hidrogena in situ en el mismo alcohol en el que se ha formado, proporcionando una mezcla de cis sertralina racémica y trans sertralina racémica.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7160098P | 1998-01-16 | 1998-01-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
UY25348A1 true UY25348A1 (es) | 1999-09-27 |
Family
ID=22102365
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY25348A UY25348A1 (es) | 1998-01-16 | 1999-01-13 | Procedimiento para preparar una cetoimina |
Country Status (48)
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU226423B1 (en) * | 1998-05-05 | 2008-12-29 | Egis Gyogyszergyar Nyrt | Process for producing a 1(2h)-naphtalene-1-ylidene derivative |
ES2226501T3 (es) * | 1998-10-30 | 2005-03-16 | Ciba Specialty Chemicals Holding Inc. | Procedimiento para la obtrencion de cetiminas. |
EP1637516A1 (en) * | 1998-11-27 | 2006-03-22 | Teva Pharmaceutical Industries Ltd | Sertraline hydrochloride polymorphs |
IN185109B (es) * | 1999-09-01 | 2000-11-18 | Torrent Pharmaceuticals Ltd | |
WO2001036378A1 (en) | 1999-11-16 | 2001-05-25 | Ciba Specialty Chemicals Holding Inc. | Process for the preparation of ketimines |
ES2241680T3 (es) * | 1999-11-16 | 2005-11-01 | Ciba Specialty Chemicals Holding Inc. | Procedimiento para la preparacion de cetiminas. |
IN187170B (es) | 2000-01-04 | 2002-02-23 | Sun Pharmaceutical Ind Ltd | |
US6552227B2 (en) * | 2000-03-14 | 2003-04-22 | Teva Pharmaceutical Industries Ltd. | Process for preparing (+)-cis-sertraline |
WO2002096860A1 (en) * | 2001-05-31 | 2002-12-05 | Orion Corporation Fermion | Process for preparing sertraline intermediates |
US6723878B2 (en) | 2001-06-15 | 2004-04-20 | Orion Corporation Fermion | Method for preparing sertraline |
KR20030061474A (ko) * | 2002-01-14 | 2003-07-22 | 한미약품 주식회사 | 서트랄린 제조용 중간체로서 사용되는 시스-라세메이트화합물의 개선된 제조방법 |
US20070260090A1 (en) | 2005-06-03 | 2007-11-08 | Hetero Drugs Limited | Highly Steroselective Synthesis of Sertraline |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4536518A (en) | 1979-11-01 | 1985-08-20 | Pfizer Inc. | Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine |
US4855500A (en) * | 1988-05-04 | 1989-08-08 | Pfizer Inc. | Process for preparing a ketimine |
HU226424B1 (en) | 1998-05-05 | 2008-12-29 | Egis Gyogyszergyar Nyrt | Process for producing enantiomer mixture for preparation of sertraline |
-
1998
- 1998-06-24 IN IN8499DE1998 patent/IN191358B/en unknown
- 1998-10-15 UA UA2000074225A patent/UA55504C2/uk unknown
- 1998-10-15 EA EA200000661A patent/EA004952B1/ru not_active IP Right Cessation
- 1998-10-15 SI SI9830331T patent/SI1047666T1/xx unknown
- 1998-10-15 PL PL341648A patent/PL192489B1/pl not_active IP Right Cessation
- 1998-10-15 AT AT98945508T patent/ATE231121T1/de not_active IP Right Cessation
- 1998-10-15 BR BR9814248-8A patent/BR9814248A/pt not_active Application Discontinuation
- 1998-10-15 AU AU92786/98A patent/AU747861B2/en not_active Ceased
- 1998-10-15 RS YUP-443/00A patent/RS49773B/sr unknown
- 1998-10-15 HU HU0101253A patent/HUP0101253A3/hu unknown
- 1998-10-15 DK DK98945508T patent/DK1047666T3/da active
- 1998-10-15 CZ CZ20002594A patent/CZ20002594A3/cs unknown
- 1998-10-15 SK SK1018-2000A patent/SK10182000A3/sk unknown
- 1998-10-15 ID IDW20001367A patent/ID24971A/id unknown
- 1998-10-15 EP EP98945508A patent/EP1047666B1/en not_active Revoked
- 1998-10-15 KR KR1020007007730A patent/KR100362788B1/ko not_active IP Right Cessation
- 1998-10-15 ES ES98945508T patent/ES2186226T3/es not_active Expired - Lifetime
- 1998-10-15 NZ NZ505027A patent/NZ505027A/xx unknown
- 1998-10-15 WO PCT/IB1998/001619 patent/WO1999036394A1/en not_active Application Discontinuation
- 1998-10-15 JP JP2000540112A patent/JP3533179B2/ja not_active Expired - Fee Related
- 1998-10-15 TR TR2000/02065T patent/TR200002065T2/xx unknown
- 1998-10-15 DE DE69810815T patent/DE69810815T2/de not_active Revoked
- 1998-10-15 US US09/380,562 patent/US6232500B1/en not_active Expired - Fee Related
- 1998-10-15 CN CN98813087A patent/CN1121381C/zh not_active Expired - Fee Related
- 1998-10-15 CA CA002315761A patent/CA2315761C/en not_active Expired - Fee Related
- 1998-10-15 IL IL13688898A patent/IL136888A0/xx active IP Right Grant
- 1998-10-15 PT PT98945508T patent/PT1047666E/pt unknown
- 1998-10-22 PA PA19988461901A patent/PA8461901A1/es unknown
- 1998-10-26 HN HN1998000167A patent/HN1998000167A/es unknown
- 1998-11-09 GT GT199800176A patent/GT199800176A/es unknown
- 1998-11-30 CO CO98070715A patent/CO5040154A1/es unknown
-
1999
- 1999-01-11 EG EG2799A patent/EG21515A/xx active
- 1999-01-11 PE PE1999000023A patent/PE20000171A1/es not_active Application Discontinuation
- 1999-01-13 MY MYPI99000116A patent/MY132956A/en unknown
- 1999-01-13 TW TW088100478A patent/TW505624B/zh not_active IP Right Cessation
- 1999-01-13 DZ DZ990006A patent/DZ2705A1/xx active
- 1999-01-13 TN TNTNSN99004A patent/TNSN99004A1/fr unknown
- 1999-01-13 MA MA25427A patent/MA24744A1/fr unknown
- 1999-01-13 UY UY25348A patent/UY25348A1/es not_active IP Right Cessation
- 1999-01-14 AP APAP/P/1999/001441A patent/AP956A/en active
- 1999-01-15 AR ARP990100129A patent/AR016168A1/es active IP Right Grant
- 1999-01-15 ZA ZA9900278A patent/ZA99278B/xx unknown
-
2000
- 2000-06-16 IS IS5538A patent/IS5538A/is unknown
- 2000-06-19 IL IL136888A patent/IL136888A/en not_active IP Right Cessation
- 2000-06-30 OA OA1200000193A patent/OA11439A/en unknown
- 2000-07-14 NO NO20003625A patent/NO20003625L/no not_active Application Discontinuation
- 2000-07-14 HR HR20000473A patent/HRP20000473A2/hr not_active Application Discontinuation
- 2000-08-07 BG BG104669A patent/BG64621B1/bg unknown
- 2000-08-07 BG BG108878A patent/BG64647B1/bg unknown
-
2001
- 2001-04-10 HK HK01102504A patent/HK1032039A1/xx not_active IP Right Cessation
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
VENC | Patent expired |
Effective date: 20190113 |