BG64540B1 - Използване на дексмедетомидин за постигане на седативен ефект в отделение за интензивна терапия - Google Patents

Използване на дексмедетомидин за постигане на седативен ефект в отделение за интензивна терапия Download PDF

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Publication number
BG64540B1
BG64540B1 BG104797A BG10479700A BG64540B1 BG 64540 B1 BG64540 B1 BG 64540B1 BG 104797 A BG104797 A BG 104797A BG 10479700 A BG10479700 A BG 10479700A BG 64540 B1 BG64540 B1 BG 64540B1
Authority
BG
Bulgaria
Prior art keywords
dexmedetomidine
patient
patients
dose
sedation
Prior art date
Application number
BG104797A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG104797A (en
Inventor
Riku Aantaa
Romeo Bachand
Esa Heinonen
Original Assignee
Orion Corporation
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26763325&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BG64540(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Orion Corporation, Abbott Laboratories filed Critical Orion Corporation
Publication of BG104797A publication Critical patent/BG104797A/xx
Publication of BG64540B1 publication Critical patent/BG64540B1/bg

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BG104797A 1998-04-01 2000-09-26 Използване на дексмедетомидин за постигане на седативен ефект в отделение за интензивна терапия BG64540B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8028798P 1998-04-01 1998-04-01
US11094498P 1998-12-04 1998-12-04

Publications (2)

Publication Number Publication Date
BG104797A BG104797A (en) 2001-07-31
BG64540B1 true BG64540B1 (bg) 2005-07-29

Family

ID=26763325

Family Applications (1)

Application Number Title Priority Date Filing Date
BG104797A BG64540B1 (bg) 1998-04-01 2000-09-26 Използване на дексмедетомидин за постигане на седативен ефект в отделение за интензивна терапия

Country Status (27)

Country Link
EP (1) EP1069893B1 (zh)
JP (1) JP4606581B2 (zh)
KR (1) KR20010034728A (zh)
CN (1) CN1168441C (zh)
AR (1) AR015744A1 (zh)
AT (1) ATE347359T1 (zh)
AU (1) AU754484B2 (zh)
BG (1) BG64540B1 (zh)
BR (1) BR9909872A (zh)
CA (1) CA2326339C (zh)
CZ (1) CZ301013B6 (zh)
DE (1) DE69934305T2 (zh)
DK (1) DK1069893T3 (zh)
EA (1) EA005524B1 (zh)
ES (1) ES2278441T3 (zh)
GB (1) GB2352972B (zh)
HU (1) HU229162B1 (zh)
IL (1) IL138416A (zh)
NO (1) NO329194B1 (zh)
NZ (1) NZ507203A (zh)
PL (1) PL192517B1 (zh)
PT (1) PT1069893E (zh)
SI (1) SI1069893T1 (zh)
SK (1) SK286160B6 (zh)
TR (1) TR200002837T2 (zh)
TW (1) TW552136B (zh)
WO (1) WO1999049854A2 (zh)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1223931B1 (en) 1999-10-29 2005-12-14 Orion Corporation Use of a imidazole derivative for the treatment or prevention of hypotension and shock
AU2003224851B2 (en) * 2002-04-08 2008-04-03 Eisai Inc. Pharmaceutical compositions containing water-soluble prodrugs of propofol and methods of administering same
US7141597B2 (en) * 2003-09-12 2006-11-28 Allergan, Inc. Nonsedating α-2 agonists
US20060058700A1 (en) * 2004-08-26 2006-03-16 Marro Dominic P Patient sedation monitor
EP2081562B1 (en) 2006-09-20 2016-02-24 The Board of Regents of The University of Texas System Methods for delivering volatile anesthetics for regional anesthesia and/or pain relief
EP2244737B1 (en) 2008-01-22 2019-04-10 The Board of Regents of The University of Texas System Volatile anesthetic compositions comprising extractive solvents for regional anesthesia and/or pain relief
CA2762107A1 (en) * 2009-05-15 2010-11-18 Recro Pharma, Inc. Sublingual dexmedetomidine compositions and methods of use thereof
DE102009050016A1 (de) 2009-05-27 2011-05-05 Modine Manufacturing Co., Racine Wärmeübertragereinheit
US20130096170A1 (en) * 2011-10-14 2013-04-18 Hospira, Inc. Methods of treating pediatric patients using dexmedetomidine
CN104470516A (zh) 2011-12-11 2015-03-25 瑞克欧制药有限公司 鼻内右美托咪定组合物和其使用方法
US8242158B1 (en) * 2012-01-04 2012-08-14 Hospira, Inc. Dexmedetomidine premix formulation
JP5921928B2 (ja) * 2012-03-28 2016-05-24 テルモ株式会社 既希釈デクスメデトミジン製剤
ES2659271T3 (es) * 2012-10-15 2018-03-14 Orion Corporation Método veterinario para aliviar la aversión al ruido
CN105473669A (zh) 2013-07-24 2016-04-06 I-技术有限公司 作为抑制剂的对映异构体左旋美托咪啶在海洋生物污损表面附着的应用
KR101948779B1 (ko) 2013-10-07 2019-05-21 테이코쿠 팔마 유에스에이, 인코포레이티드 덱스메데토미딘 경피 전달 장치 및 이의 사용 방법
US10987342B2 (en) 2013-10-07 2021-04-27 Teikoku Pharma Usa, Inc. Methods and compositions for transdermal delivery of a non-sedative amount of dexmedetomidine
JP6310070B2 (ja) 2013-10-07 2018-04-11 テイコク ファーマ ユーエスエー インコーポレーテッド デクスメデトミジン経皮組成物を用いる、注意欠陥多動性障害、不安症及び不眠症の治療法及び組成物
CN113975273B (zh) * 2020-07-27 2023-07-11 宜昌人福药业有限责任公司 一种抗焦虑用纳米混悬鼻腔喷雾剂及其制备方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4544664A (en) * 1981-07-10 1985-10-01 Farmos Group, Ltd. Antihypertensive substituted imidazole derivatives
US4670455A (en) * 1984-12-04 1987-06-02 Farmos-Yhtyma Oy Method of bringing about sedation and/or analgesia in a mammal
US4910214A (en) * 1987-07-16 1990-03-20 Farmos Yhtyma Oy Optical isomer of an imidazole derivative medetomidine as an alpha-2-receptor agonist
US5344840A (en) * 1988-02-29 1994-09-06 Orion-Yhtyma Oy 4-substituted imidazole derivatives useful in perioperative care
US5712301A (en) * 1993-08-25 1998-01-27 Orion-yhtyma Oy Use of dexmedetomidine for treating ethanol-induced neurodegeneration

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2215206B (en) * 1988-02-29 1991-07-03 Farmos Oy 4-substituted imidazole derivatives useful in perioperative care
US5217718A (en) * 1989-08-18 1993-06-08 Cygnus Therapeutic Systems Method and device for administering dexmedetomidine transdermally
US5124157A (en) * 1989-08-18 1992-06-23 Cygnus Therapeutic Systems Method and device for administering dexmedetomidine transdermally
FI894911A0 (fi) * 1989-10-17 1989-10-17 Farmos Oy En terapeutiskt vaerdefull foerening.

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4544664A (en) * 1981-07-10 1985-10-01 Farmos Group, Ltd. Antihypertensive substituted imidazole derivatives
US4670455A (en) * 1984-12-04 1987-06-02 Farmos-Yhtyma Oy Method of bringing about sedation and/or analgesia in a mammal
US4910214A (en) * 1987-07-16 1990-03-20 Farmos Yhtyma Oy Optical isomer of an imidazole derivative medetomidine as an alpha-2-receptor agonist
US5344840A (en) * 1988-02-29 1994-09-06 Orion-Yhtyma Oy 4-substituted imidazole derivatives useful in perioperative care
US5712301A (en) * 1993-08-25 1998-01-27 Orion-yhtyma Oy Use of dexmedetomidine for treating ethanol-induced neurodegeneration

Also Published As

Publication number Publication date
JP4606581B2 (ja) 2011-01-05
AU3149499A (en) 1999-10-18
NZ507203A (en) 2003-03-28
NO20004931D0 (no) 2000-09-29
TR200002837T2 (tr) 2001-01-22
CN1295473A (zh) 2001-05-16
CZ301013B6 (cs) 2009-10-14
KR20010034728A (ko) 2001-04-25
HU229162B1 (hu) 2013-09-30
AU754484B2 (en) 2002-11-14
CA2326339C (en) 2008-12-23
PT1069893E (pt) 2007-01-31
SK14362000A3 (sk) 2002-03-05
BG104797A (en) 2001-07-31
IL138416A0 (en) 2001-10-31
CZ20003484A3 (cs) 2002-01-16
CA2326339A1 (en) 1999-10-07
IL138416A (en) 2005-07-25
EA005524B1 (ru) 2005-04-28
PL192517B1 (pl) 2006-10-31
CN1168441C (zh) 2004-09-29
SI1069893T1 (sl) 2007-04-30
JP2002509880A (ja) 2002-04-02
GB2352972B (en) 2003-05-21
NO329194B1 (no) 2010-09-13
PL343553A1 (en) 2001-08-27
GB2352972A (en) 2001-02-14
NO20004931L (no) 2000-09-29
EP1069893B1 (en) 2006-12-06
HUP0101498A1 (hu) 2002-03-28
BR9909872A (pt) 2007-11-20
AR015744A1 (es) 2001-05-16
TW552136B (en) 2003-09-11
ES2278441T3 (es) 2007-08-01
DK1069893T3 (da) 2007-03-19
GB0024932D0 (en) 2000-11-29
DE69934305D1 (de) 2007-01-18
WO1999049854A3 (en) 1999-11-18
HUP0101498A3 (en) 2002-06-28
ATE347359T1 (de) 2006-12-15
EA200001010A1 (ru) 2001-02-26
EP1069893A2 (en) 2001-01-24
WO1999049854A2 (en) 1999-10-07
DE69934305T2 (de) 2007-07-12
SK286160B6 (sk) 2008-04-07

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