BG63872B1 - Азоли, съдържащи естери, с аминокиселини като противогъбични средства - Google Patents
Азоли, съдържащи естери, с аминокиселини като противогъбични средства Download PDFInfo
- Publication number
- BG63872B1 BG63872B1 BG103171A BG10317199A BG63872B1 BG 63872 B1 BG63872 B1 BG 63872B1 BG 103171 A BG103171 A BG 103171A BG 10317199 A BG10317199 A BG 10317199A BG 63872 B1 BG63872 B1 BG 63872B1
- Authority
- BG
- Bulgaria
- Prior art keywords
- formula
- phenyl
- triazol
- piperazinyl
- acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97200374 | 1997-02-11 | ||
| EP97203228 | 1997-10-15 | ||
| PCT/EP1998/000646 WO1998034934A1 (en) | 1997-02-11 | 1998-02-03 | Amino acid ester containing azole antifungals |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BG103171A BG103171A (en) | 1999-09-30 |
| BG63872B1 true BG63872B1 (bg) | 2003-04-30 |
Family
ID=26146124
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG103171A BG63872B1 (bg) | 1997-02-11 | 1999-02-11 | Азоли, съдържащи естери, с аминокиселини като противогъбични средства |
Country Status (31)
| Country | Link |
|---|---|
| US (3) | US6262052B1 (hu) |
| EP (1) | EP0958289B1 (hu) |
| JP (1) | JP4347911B2 (hu) |
| KR (1) | KR100509171B1 (hu) |
| CN (1) | CN1238353C (hu) |
| AT (1) | ATE270290T1 (hu) |
| AU (1) | AU725302C (hu) |
| BG (1) | BG63872B1 (hu) |
| BR (1) | BR9809744A (hu) |
| CA (1) | CA2262791C (hu) |
| CZ (1) | CZ297197B6 (hu) |
| DE (1) | DE69824834T2 (hu) |
| DK (1) | DK0958289T3 (hu) |
| EE (1) | EE03876B1 (hu) |
| ES (1) | ES2224364T3 (hu) |
| HU (1) | HU227744B1 (hu) |
| ID (1) | ID21755A (hu) |
| IL (2) | IL128513A (hu) |
| MY (1) | MY129537A (hu) |
| NO (1) | NO316668B1 (hu) |
| NZ (1) | NZ334477A (hu) |
| PL (1) | PL191152B1 (hu) |
| PT (1) | PT958289E (hu) |
| RU (1) | RU2197489C2 (hu) |
| SI (1) | SI0958289T1 (hu) |
| SK (1) | SK284910B6 (hu) |
| TR (1) | TR199900584T2 (hu) |
| TW (1) | TW495508B (hu) |
| UA (1) | UA61919C2 (hu) |
| WO (1) | WO1998034934A1 (hu) |
| ZA (1) | ZA981079B (hu) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0957101A1 (en) * | 1998-05-14 | 1999-11-17 | Janssen Pharmaceutica N.V. | Water soluble azoles as broad-spectrum antifungals |
| AU1915500A (en) | 1998-11-20 | 2000-06-13 | Bristol-Myers Squibb Company | Water soluble prodrugs of azole compounds |
| EP1177192B1 (en) | 1999-05-04 | 2003-03-19 | Janssen Pharmaceutica N.V. | Antifungal ethers |
| US20060199778A1 (en) * | 2001-09-19 | 2006-09-07 | Rutledge Ellis-Behnke | Methods and products related to non-viral transfection |
| ITMI20032020A1 (it) * | 2003-10-17 | 2005-04-18 | Italfarmaco Spa | Nuovi agenti antifungini azolici con diminuita interazione con i citocromi metabolici |
| CA2798002C (en) * | 2010-05-19 | 2019-12-03 | Sandoz Ag | Process for the preparation of chiral triazolones |
| BR102019004480B1 (pt) * | 2018-03-08 | 2023-03-28 | Dow Agrosciences Llc | Picolinamidas como fungicidas |
| CN111138421A (zh) * | 2019-12-26 | 2020-05-12 | 上海英诺富成生物科技有限公司 | 抗真菌水溶性化合物及其制备方法与应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4218458A (en) | 1978-06-23 | 1980-08-19 | Janssen Pharmaceutica, N.V. | Heterocyclic derivatives of (4-aryloxy-methyl-1,3-dioxolan-2-yl)methyl-1H-imidazoles and 1H-1,2,4-triazoles |
| US4791111A (en) * | 1985-12-23 | 1988-12-13 | Janssen Pharmaceutica, N.V. | [[4-[4-(4-phenyl-1-piperazinyl)phenoxymethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazoles and 1H-1,2,4-triazoles having anti-microbial properties |
| US4916134A (en) | 1987-03-25 | 1990-04-10 | Janssen Pharmacuetica N.V. | 4-[4-[4-[4-[[2-(2,4-difluorophenyl)-2-(1H-azolylmethyl)-1,3-dioxolan-4-yl]me]phenyl]-1-piperazinyl]phenyl]triazolones |
| CA1331757C (en) | 1988-02-29 | 1994-08-30 | Janssen Pharmaceutica Naamloze Vennootschap | 5-lipoxygenase inhibiting 4-(4-phenyl-1-piperazinyl)phenols |
| HU221189B1 (en) | 1992-03-18 | 2002-08-28 | Janssen Pharmaceutica Nv | Itraconazole and saperconazole stereoisomers, their cyclodextrin complexes and pharmaceutical compositions containing them and process for producing them |
| PT736030E (pt) * | 1993-12-21 | 2002-01-30 | Schering Corp | Antifungicos de tetra-hidrofurano |
| SI0741737T1 (en) * | 1994-01-24 | 2000-02-29 | Janssen Pharmaceutica N.V. | Watersoluble azole antifungals |
| HUP9701690A3 (en) | 1995-06-02 | 1998-04-28 | Schering Corp Kenilwort | Tetrahydrofuran derivatives as antifungals and pharmaceutical compositions containing the same |
| ATE247108T1 (de) * | 1995-06-19 | 2003-08-15 | Schering Corp | Antifungale tetrahydrofurane |
-
1998
- 1998-02-03 TR TR1999/00584T patent/TR199900584T2/xx unknown
- 1998-02-03 EP EP98908064A patent/EP0958289B1/en not_active Expired - Lifetime
- 1998-02-03 KR KR10-1999-7001983A patent/KR100509171B1/ko active IP Right Grant
- 1998-02-03 AT AT98908064T patent/ATE270290T1/de active
- 1998-02-03 SI SI9830687T patent/SI0958289T1/xx unknown
- 1998-02-03 CA CA002262791A patent/CA2262791C/en not_active Expired - Lifetime
- 1998-02-03 JP JP53376398A patent/JP4347911B2/ja not_active Expired - Lifetime
- 1998-02-03 CN CNB988011352A patent/CN1238353C/zh not_active Expired - Lifetime
- 1998-02-03 ID IDW990505A patent/ID21755A/id unknown
- 1998-02-03 WO PCT/EP1998/000646 patent/WO1998034934A1/en active IP Right Grant
- 1998-02-03 CZ CZ0283599A patent/CZ297197B6/cs not_active IP Right Cessation
- 1998-02-03 EE EEP199900100A patent/EE03876B1/xx unknown
- 1998-02-03 HU HU0001050A patent/HU227744B1/hu unknown
- 1998-02-03 NZ NZ334477A patent/NZ334477A/en not_active IP Right Cessation
- 1998-02-03 RU RU99106585/04A patent/RU2197489C2/ru active
- 1998-02-03 DE DE69824834T patent/DE69824834T2/de not_active Expired - Lifetime
- 1998-02-03 ES ES98908064T patent/ES2224364T3/es not_active Expired - Lifetime
- 1998-02-03 SK SK1059-99A patent/SK284910B6/sk not_active IP Right Cessation
- 1998-02-03 IL IL12851398A patent/IL128513A/en not_active IP Right Cessation
- 1998-02-03 PT PT98908064T patent/PT958289E/pt unknown
- 1998-02-03 BR BR9809744-0A patent/BR9809744A/pt not_active Application Discontinuation
- 1998-02-03 AU AU66207/98A patent/AU725302C/en not_active Expired
- 1998-02-03 DK DK98908064T patent/DK0958289T3/da active
- 1998-02-03 US US09/355,369 patent/US6262052B1/en not_active Expired - Lifetime
- 1998-02-03 PL PL332008A patent/PL191152B1/pl unknown
- 1998-02-09 TW TW087101662A patent/TW495508B/zh not_active IP Right Cessation
- 1998-02-09 MY MYPI98000513A patent/MY129537A/en unknown
- 1998-02-10 ZA ZA9801079A patent/ZA981079B/xx unknown
- 1998-03-02 UA UA99020835A patent/UA61919C2/uk unknown
-
1999
- 1999-02-02 NO NO19990484A patent/NO316668B1/no not_active IP Right Cessation
- 1999-02-11 BG BG103171A patent/BG63872B1/bg unknown
-
2001
- 2001-05-04 US US09/848,989 patent/US6512116B2/en not_active Expired - Lifetime
-
2002
- 2002-04-23 IL IL149285A patent/IL149285A/en not_active IP Right Cessation
- 2002-11-15 US US10/298,038 patent/US6703506B2/en not_active Expired - Lifetime
Also Published As
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