ATE247108T1 - Antifungale tetrahydrofurane - Google Patents

Antifungale tetrahydrofurane

Info

Publication number
ATE247108T1
ATE247108T1 AT96921326T AT96921326T ATE247108T1 AT E247108 T1 ATE247108 T1 AT E247108T1 AT 96921326 T AT96921326 T AT 96921326T AT 96921326 T AT96921326 T AT 96921326T AT E247108 T1 ATE247108 T1 AT E247108T1
Authority
AT
Austria
Prior art keywords
ester
group
tetrahydrofuranes
antifungal
ether
Prior art date
Application number
AT96921326T
Other languages
English (en)
Inventor
Raymond G Lovey
Viyyoor M Girijavallabhan
Anil K Saksena
Russell E Pike
Frank Bennet
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ATE247108T1 publication Critical patent/ATE247108T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT96921326T 1995-06-19 1996-06-17 Antifungale tetrahydrofurane ATE247108T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30595P 1995-06-19 1995-06-19
US59685296A 1996-02-05 1996-02-05
PCT/US1996/009242 WO1997000255A1 (en) 1995-06-19 1996-06-17 Tetrahydrofuran antifungals

Publications (1)

Publication Number Publication Date
ATE247108T1 true ATE247108T1 (de) 2003-08-15

Family

ID=26667465

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96921326T ATE247108T1 (de) 1995-06-19 1996-06-17 Antifungale tetrahydrofurane

Country Status (10)

Country Link
EP (1) EP0837859B1 (de)
JP (1) JPH11507668A (de)
AT (1) ATE247108T1 (de)
AU (1) AU6257396A (de)
CA (1) CA2224707A1 (de)
DE (1) DE69629474T2 (de)
ES (1) ES2203707T3 (de)
IL (1) IL118668A0 (de)
MX (1) MX9710270A (de)
WO (1) WO1997000255A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL128513A (en) * 1997-02-11 2002-11-10 Janssen Pharmaceutica Nv Aster derivatives of amino acids of Azuli substance against fungi, their preparation and pharmaceutical preparations containing them
EP0957101A1 (de) * 1998-05-14 1999-11-17 Janssen Pharmaceutica N.V. Wasserlösliche Azole als Breitspektrum-antifungus
CN1349540A (zh) * 1999-05-04 2002-05-15 詹森药业有限公司 抗真菌的醚类
WO2010027496A1 (en) * 2008-09-08 2010-03-11 Wu Nian Triazole antifungal agents
WO2011144655A1 (en) 2010-05-19 2011-11-24 Sandoz Ag Process for the preparation of chiral hydrazides
EP2571869B1 (de) 2010-05-19 2015-09-23 Sandoz AG Reinigung von posaconazol und posaconazol-zwischenprodukten
EP2571868B1 (de) 2010-05-19 2016-05-04 Sandoz AG Reinigung von posaconazol und posaconazol-zwischenprodukten
CA2798002C (en) 2010-05-19 2019-12-03 Sandoz Ag Process for the preparation of chiral triazolones
CN108329303A (zh) 2011-06-16 2018-07-27 桑多斯股份公司 制备手性化合物的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL103558A0 (en) * 1991-10-30 1993-03-15 Schering Corp Tri-substituted tetrahydrofuran antifungals
SK283035B6 (sk) * 1993-12-21 2003-02-04 Schering Corporation Tetrahydrofuránová zlúčenina, spôsob jej prípravy, jej farmaceuticky prijateľný ester, soľ a farmaceutický prostriedok
NZ278882A (en) * 1994-01-24 1997-06-24 Janssen Pharmaceutica Nv Piperazine-containing azole antifungal compounds

Also Published As

Publication number Publication date
MX9710270A (es) 1998-08-30
CA2224707A1 (en) 1997-01-03
AU6257396A (en) 1997-01-15
EP0837859B1 (de) 2003-08-13
JPH11507668A (ja) 1999-07-06
DE69629474T2 (de) 2004-06-24
DE69629474D1 (de) 2003-09-18
IL118668A0 (en) 1996-10-16
ES2203707T3 (es) 2004-04-16
WO1997000255A1 (en) 1997-01-03
EP0837859A1 (de) 1998-04-29

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties