ATE247108T1 - Antifungale tetrahydrofurane - Google Patents

Antifungale tetrahydrofurane

Info

Publication number
ATE247108T1
ATE247108T1 AT96921326T AT96921326T ATE247108T1 AT E247108 T1 ATE247108 T1 AT E247108T1 AT 96921326 T AT96921326 T AT 96921326T AT 96921326 T AT96921326 T AT 96921326T AT E247108 T1 ATE247108 T1 AT E247108T1
Authority
AT
Austria
Prior art keywords
ester
group
tetrahydrofuranes
antifungal
ether
Prior art date
Application number
AT96921326T
Other languages
English (en)
Inventor
Raymond G Lovey
Viyyoor M Girijavallabhan
Anil K Saksena
Russell E Pike
Frank Bennet
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ATE247108T1 publication Critical patent/ATE247108T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT96921326T 1995-06-19 1996-06-17 Antifungale tetrahydrofurane ATE247108T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30595P 1995-06-19 1995-06-19
US59685296A 1996-02-05 1996-02-05
PCT/US1996/009242 WO1997000255A1 (en) 1995-06-19 1996-06-17 Tetrahydrofuran antifungals

Publications (1)

Publication Number Publication Date
ATE247108T1 true ATE247108T1 (de) 2003-08-15

Family

ID=26667465

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96921326T ATE247108T1 (de) 1995-06-19 1996-06-17 Antifungale tetrahydrofurane

Country Status (10)

Country Link
EP (1) EP0837859B1 (de)
JP (1) JPH11507668A (de)
AT (1) ATE247108T1 (de)
AU (1) AU6257396A (de)
CA (1) CA2224707A1 (de)
DE (1) DE69629474T2 (de)
ES (1) ES2203707T3 (de)
IL (1) IL118668A0 (de)
MX (1) MX9710270A (de)
WO (1) WO1997000255A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69824834T2 (de) * 1997-02-11 2005-07-21 Janssen Pharmaceutica N.V. Azole enthaltende antifungale aminosäure-ester
EP0957101A1 (de) * 1998-05-14 1999-11-17 Janssen Pharmaceutica N.V. Wasserlösliche Azole als Breitspektrum-antifungus
EE200100575A (et) * 1999-05-04 2003-02-17 Janssen Pharmaceutica N.V. Seentevastased eetrid, nende valmistamismeetod jakasutamine, kompositsioon ja selle valmistamismeetod
JP2012502028A (ja) * 2008-09-08 2012-01-26 ウ，ニアン トリアゾール抗真菌剤
AU2011254658B2 (en) * 2010-05-19 2016-02-18 Sandoz Ag Purification of posaconazole and of posaconazole intermediates
WO2011144656A1 (en) * 2010-05-19 2011-11-24 Sandoz Ag Preparation of posaconazole intermediates
WO2011144653A1 (en) 2010-05-19 2011-11-24 Sandoz Ag Process for the preparation of chiral triazolones
CN102892750B (zh) 2010-05-19 2016-03-02 桑多斯股份公司 制备手性酰肼的方法
CA2838051C (en) 2011-06-16 2019-09-24 Sandoz Ag Process for the preparation of a chiral compound

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL103558A0 (en) * 1991-10-30 1993-03-15 Schering Corp Tri-substituted tetrahydrofuran antifungals
AU681753B2 (en) * 1993-12-21 1997-09-04 Merck Sharp & Dohme Corp. Tetrahydrofuran antifungals
NZ278882A (en) * 1994-01-24 1997-06-24 Janssen Pharmaceutica Nv Piperazine-containing azole antifungal compounds

Also Published As

Publication number Publication date
AU6257396A (en) 1997-01-15
MX9710270A (es) 1998-08-30
DE69629474T2 (de) 2004-06-24
IL118668A0 (en) 1996-10-16
EP0837859A1 (de) 1998-04-29
WO1997000255A1 (en) 1997-01-03
DE69629474D1 (de) 2003-09-18
EP0837859B1 (de) 2003-08-13
ES2203707T3 (es) 2004-04-16
JPH11507668A (ja) 1999-07-06
CA2224707A1 (en) 1997-01-03

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties